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The map label for this gene is manA [H]

Identifier: 18310169

GI number: 18310169

Start: 1383211

End: 1384188

Strand: Reverse

Name: manA [H]

Synonym: CPE1187

Alternate gene names: 18310169

Gene position: 1384188-1383211 (Counterclockwise)

Preceding gene: 18310172

Following gene: 18310168

Centisome position: 45.66

GC content: 30.27

Gene sequence:

>978_bases
ATGTATCCAATAAGATTTGAAAACTTATACTATGATAAAGTTTGGGGTGGAAGAGATTTCGAACTTTTCAGAGACAATAT
GCCAGAGGGAATGATAGGAGAAACTTGGGATGTTGCTTGTCATCAAAATGGAATGAGTATAGTTGAAAATGGTGAATATA
AAGGGTTAAGATTTGATGAGTTAATAGATAAATTAGGAAGTGACTTAGTAGGTACTGAAATATCAAAAGAGAAATTTCCT
CTACTTATAAAATTAATAAACGCTAAGGATAAATTATCAGTTCAAGTTCATCCAAATGATGAATATGGTATGAGAGTTGA
AGGAGAGCTTGGAAAAACTGAAATTTGGTATGTTGTTGAAGCTTTTGAAGGAGCTAATTTAATAGTAGGAACAAAGGATT
GTACTAAAGAACAATTTGTTAAAGCTATAGAAACTGGTGAATTTGATCAGTATTTAAATAGAGTAGAAGTAAAAAAAGGG
GATACTTTCTTTGTAAGAAGTGGACTAGTTCATGCTATATGCGAAGGTGTTATAATAGCTGAAATCCAACAAAATAGTGA
TACAACTTATAGAGTATATGACTATAACAGAGGAAGAGAAATCCATGTTGAAAAAGCTTTAGATTGTATCGATTTCTCAT
TAAAAGGAGAAAAAGCTAAGGGATTAAAAGTTTCATATGATCAATATGATAAAACTTATCTTTCACTATGTGAATATTTC
TCATTAGAAAAATATGATATACATGGAGTATGTGAAGAAGAGAGTGATAAAGAAAGATTCTTCATATTTACATGTGTTGA
AGGAGAAGGAATCATAACTTCAGAAGAAGGAGAATTAGCAATTAAAAAAGGAGATAGTATATTCATACCTGCATCCTTAG
GAAAATATTCTTTAAAAGGAAACATGACATTATTAAAGAGTTATGTTCCAAAAGAAGGTGCTGTTGAAGAGGAAATACTT
TCAGTAGTAAAAGCTTAA

Upstream 100 bases:

>100_bases
TTTACAATGCAATATATGTAGAAATATTGTATTATATATAGGAAGGATATAATTAAGTAGCATTAATTATACAAATAAAC
TAGACTAGGGGGAATACTAA

Downstream 100 bases:

>100_bases
TAAGATTTATTAAGAAAATTAATAATATATTTAATTGTATAATTTAAAGAAAGAGTATATGAAAACTAATTTAAAATAAT
AAATGATTATGAATTACTTT

Product: mannose-6-phosphate isomerase, class I

Products: NA

Alternate protein names: Phosphohexomutase; Phosphomannose isomerase; PMI [H]

Number of amino acids: Translated: 325; Mature: 325

Protein sequence:

>325_residues
MYPIRFENLYYDKVWGGRDFELFRDNMPEGMIGETWDVACHQNGMSIVENGEYKGLRFDELIDKLGSDLVGTEISKEKFP
LLIKLINAKDKLSVQVHPNDEYGMRVEGELGKTEIWYVVEAFEGANLIVGTKDCTKEQFVKAIETGEFDQYLNRVEVKKG
DTFFVRSGLVHAICEGVIIAEIQQNSDTTYRVYDYNRGREIHVEKALDCIDFSLKGEKAKGLKVSYDQYDKTYLSLCEYF
SLEKYDIHGVCEEESDKERFFIFTCVEGEGIITSEEGELAIKKGDSIFIPASLGKYSLKGNMTLLKSYVPKEGAVEEEIL
SVVKA

Sequences:

>Translated_325_residues
MYPIRFENLYYDKVWGGRDFELFRDNMPEGMIGETWDVACHQNGMSIVENGEYKGLRFDELIDKLGSDLVGTEISKEKFP
LLIKLINAKDKLSVQVHPNDEYGMRVEGELGKTEIWYVVEAFEGANLIVGTKDCTKEQFVKAIETGEFDQYLNRVEVKKG
DTFFVRSGLVHAICEGVIIAEIQQNSDTTYRVYDYNRGREIHVEKALDCIDFSLKGEKAKGLKVSYDQYDKTYLSLCEYF
SLEKYDIHGVCEEESDKERFFIFTCVEGEGIITSEEGELAIKKGDSIFIPASLGKYSLKGNMTLLKSYVPKEGAVEEEIL
SVVKA
>Mature_325_residues
MYPIRFENLYYDKVWGGRDFELFRDNMPEGMIGETWDVACHQNGMSIVENGEYKGLRFDELIDKLGSDLVGTEISKEKFP
LLIKLINAKDKLSVQVHPNDEYGMRVEGELGKTEIWYVVEAFEGANLIVGTKDCTKEQFVKAIETGEFDQYLNRVEVKKG
DTFFVRSGLVHAICEGVIIAEIQQNSDTTYRVYDYNRGREIHVEKALDCIDFSLKGEKAKGLKVSYDQYDKTYLSLCEYF
SLEKYDIHGVCEEESDKERFFIFTCVEGEGIITSEEGELAIKKGDSIFIPASLGKYSLKGNMTLLKSYVPKEGAVEEEIL
SVVKA

Specific function: Unknown

COG id: COG1482

COG function: function code G; Phosphomannose isomerase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mannose-6-phosphate isomerase type 1 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011051
- InterPro:   IPR001250
- InterPro:   IPR014628
- InterPro:   IPR014710 [H]

Pfam domain/function: PF01238 PMI_typeI [H]

EC number: =5.3.1.8 [H]

Molecular weight: Translated: 37032; Mature: 37032

Theoretical pI: Translated: 4.51; Mature: 4.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYPIRFENLYYDKVWGGRDFELFRDNMPEGMIGETWDVACHQNGMSIVENGEYKGLRFDE
CCCEEECCEEEECCCCCCCHHHHHCCCCCCCCCCCEEEEECCCCCEEEECCCCCCCCHHH
LIDKLGSDLVGTEISKEKFPLLIKLINAKDKLSVQVHPNDEYGMRVEGELGKTEIWYVVE
HHHHHCCCCCCCCCCCCCCCEEEEEECCCCEEEEEECCCCCCCEEEECCCCCEEEEEEEE
AFEGANLIVGTKDCTKEQFVKAIETGEFDQYLNRVEVKKGDTFFVRSGLVHAICEGVIIA
ECCCCEEEEECCCCCHHHHHHHHHCCCHHHHHHHEEECCCCEEEEHHHHHHHHHCCEEEE
EIQQNSDTTYRVYDYNRGREIHVEKALDCIDFSLKGEKAKGLKVSYDQYDKTYLSLCEYF
EEECCCCCEEEEEECCCCCEEEHHHHHHHHCEEECCCCCCCEEEEHHHHHHHHHHHHHHH
SLEKYDIHGVCEEESDKERFFIFTCVEGEGIITSEEGELAIKKGDSIFIPASLGKYSLKG
CCCCEEEEEECCCCCCCCEEEEEEEECCCCEEECCCCCEEEECCCEEEEECCCCCEEECC
NMTLLKSYVPKEGAVEEEILSVVKA
CHHHHHHHCCCCCCHHHHHHHHHCC
>Mature Secondary Structure
MYPIRFENLYYDKVWGGRDFELFRDNMPEGMIGETWDVACHQNGMSIVENGEYKGLRFDE
CCCEEECCEEEECCCCCCCHHHHHCCCCCCCCCCCEEEEECCCCCEEEECCCCCCCCHHH
LIDKLGSDLVGTEISKEKFPLLIKLINAKDKLSVQVHPNDEYGMRVEGELGKTEIWYVVE
HHHHHCCCCCCCCCCCCCCCEEEEEECCCCEEEEEECCCCCCCEEEECCCCCEEEEEEEE
AFEGANLIVGTKDCTKEQFVKAIETGEFDQYLNRVEVKKGDTFFVRSGLVHAICEGVIIA
ECCCCEEEEECCCCCHHHHHHHHHCCCHHHHHHHEEECCCCEEEEHHHHHHHHHCCEEEE
EIQQNSDTTYRVYDYNRGREIHVEKALDCIDFSLKGEKAKGLKVSYDQYDKTYLSLCEYF
EEECCCCCEEEEEECCCCCEEEHHHHHHHHCEEECCCCCCCEEEEHHHHHHHHHHHHHHH
SLEKYDIHGVCEEESDKERFFIFTCVEGEGIITSEEGELAIKKGDSIFIPASLGKYSLKG
CCCCEEEEEECCCCCCCCEEEEEEEECCCCEEECCCCCEEEECCCEEEEECCCCCEEECC
NMTLLKSYVPKEGAVEEEILSVVKA
CHHHHHHHCCCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]