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The map label for this gene is citC [H]

Identifier: 18310128

GI number: 18310128

Start: 1340264

End: 1341301

Strand: Direct

Name: citC [H]

Synonym: CPE1146

Alternate gene names: 18310128

Gene position: 1340264-1341301 (Clockwise)

Preceding gene: 18310125

Following gene: 18310129

Centisome position: 44.21

GC content: 24.57

Gene sequence:

>1038_bases
ATGTCAGAATGGAATTATGAAAATACTTTTGAAGAGGAGTTAACTTTCTTTTCCTTTAATCCACAAATAAATAAAAAATA
TAAATTTCAAGTTGAAGAATTTTTAAAGAAAGAAAATTTGCGATTTGTAAAAAGTATTAACTTTACAGTGTGTGTATTTA
ATAATAAAGAGCTTATAGCTACTGGATCCTTAGATGAATATATACTAAAATGTTTTGCTGTTAGAAGTGATTATAGAAAA
AAAGGCATTAGTGAGAAGATATTAAGAATATTAACAGAAAAAGCTTTTGAAAATGGAGAAACACATCTTTTTATATACAC
AAAACCAAAGAACTCAAAGCTTTTTGAAAGTCTAGGTTATCACCAATTAATAAATATTCCTAATTTAGTTTCTCTATTAG
AAAATAAATCAACAGGAATTAGAACTTATATACTTAATTTACAAAAAAAATCTTATCTACAAGGAGTAAAGGTAGCTTCA
ATAGTTATGAATTGTAATCCATTTACAAATGGGCATAAGTATTTAATTGAAAAAGCTTCAAAGGAAAATGATGTTGTTCA
TTTATTTATATTAACAGAAGATAAATCAGAATTTTCTACTAAAGATAGAATTAACATGGTTAAACTTGGAACTAAACATC
TAAAAAATGTTTTAATACATGAGGCGGGAAAATATATTATTTCAAGTGCCACATTTCCTTCATACTTTATAAAAGAACAA
AAAAATATTACAAAAGCTCATGCTTATTTAGATTTAACTTTATTTTGTGAGTATATATCAAAAGCATTAAACATTAAATA
CAGATATGTAGGAGAAGAACCTTTTTCGAATTTAACAAATGAATATAACCAATATATGAAAGAGATACTTCCTAAACATA
ATATACAAGTCATAGAAGTTAAAAGATTAAAAGAAGATGGTCAAGCAATTTCAGCTTCTAGTGTAAGGAGTTTTTTGAAA
GAAGGAAATCTAGAAAAAGTAGAGAGTTTAGTTCCTAAAACAACATTTGATTATTTATTAAACATAAGTAAAAAATAA

Upstream 100 bases:

>100_bases
AATATAGAAAATCTATTGTACTTTAAAAAGAGTGTGGTAAAATAAAATTGTAAGTAACAAATGTTTAAAAAATAAACAAA
TGTTAAAAAGGAGAAATGAA

Downstream 100 bases:

>100_bases
TAAATATTTTGGAGGGGTTTCATATGGAAATTAAAAAACCAGCTTTAGCTGGAACATTAGAATCAAGTGATTGTATAGTT
TCAGTAGAGCCTTCAATGGA

Product: citrate (pro-3S)-lyase ligase

Products: NA

Alternate protein names: Acetate:SH-citrate lyase ligase; Citrate lyase synthetase [H]

Number of amino acids: Translated: 345; Mature: 344

Protein sequence:

>345_residues
MSEWNYENTFEEELTFFSFNPQINKKYKFQVEEFLKKENLRFVKSINFTVCVFNNKELIATGSLDEYILKCFAVRSDYRK
KGISEKILRILTEKAFENGETHLFIYTKPKNSKLFESLGYHQLINIPNLVSLLENKSTGIRTYILNLQKKSYLQGVKVAS
IVMNCNPFTNGHKYLIEKASKENDVVHLFILTEDKSEFSTKDRINMVKLGTKHLKNVLIHEAGKYIISSATFPSYFIKEQ
KNITKAHAYLDLTLFCEYISKALNIKYRYVGEEPFSNLTNEYNQYMKEILPKHNIQVIEVKRLKEDGQAISASSVRSFLK
EGNLEKVESLVPKTTFDYLLNISKK

Sequences:

>Translated_345_residues
MSEWNYENTFEEELTFFSFNPQINKKYKFQVEEFLKKENLRFVKSINFTVCVFNNKELIATGSLDEYILKCFAVRSDYRK
KGISEKILRILTEKAFENGETHLFIYTKPKNSKLFESLGYHQLINIPNLVSLLENKSTGIRTYILNLQKKSYLQGVKVAS
IVMNCNPFTNGHKYLIEKASKENDVVHLFILTEDKSEFSTKDRINMVKLGTKHLKNVLIHEAGKYIISSATFPSYFIKEQ
KNITKAHAYLDLTLFCEYISKALNIKYRYVGEEPFSNLTNEYNQYMKEILPKHNIQVIEVKRLKEDGQAISASSVRSFLK
EGNLEKVESLVPKTTFDYLLNISKK
>Mature_344_residues
SEWNYENTFEEELTFFSFNPQINKKYKFQVEEFLKKENLRFVKSINFTVCVFNNKELIATGSLDEYILKCFAVRSDYRKK
GISEKILRILTEKAFENGETHLFIYTKPKNSKLFESLGYHQLINIPNLVSLLENKSTGIRTYILNLQKKSYLQGVKVASI
VMNCNPFTNGHKYLIEKASKENDVVHLFILTEDKSEFSTKDRINMVKLGTKHLKNVLIHEAGKYIISSATFPSYFIKEQK
NITKAHAYLDLTLFCEYISKALNIKYRYVGEEPFSNLTNEYNQYMKEILPKHNIQVIEVKRLKEDGQAISASSVRSFLKE
GNLEKVESLVPKTTFDYLLNISKK

Specific function: Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase [H]

COG id: COG3053

COG function: function code C; Citrate lyase synthetase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 N-acetyltransferase domain [H]

Homologues:

Organism=Escherichia coli, GI87081765, Length=324, Percent_Identity=37.6543209876543, Blast_Score=241, Evalue=5e-65,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000182
- InterPro:   IPR016181
- InterPro:   IPR005216
- InterPro:   IPR013166
- InterPro:   IPR004821
- InterPro:   IPR014729 [H]

Pfam domain/function: PF08218 Citrate_ly_lig [H]

EC number: =6.2.1.22 [H]

Molecular weight: Translated: 40229; Mature: 40098

Theoretical pI: Translated: 9.57; Mature: 9.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEWNYENTFEEELTFFSFNPQINKKYKFQVEEFLKKENLRFVKSINFTVCVFNNKELIA
CCCCCCCCCHHHCCEEEEECCCCCCCHHHHHHHHHHHCCCCEEEECCEEEEEECCCEEEE
TGSLDEYILKCFAVRSDYRKKGISEKILRILTEKAFENGETHLFIYTKPKNSKLFESLGY
ECCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHCCH
HQLINIPNLVSLLENKSTGIRTYILNLQKKSYLQGVKVASIVMNCNPFTNGHKYLIEKAS
HHHCCCHHHHHHHHCCCCCEEEEEEECHHHHHHHHHEEEHEEEECCCCCCCHHHHHHHCC
KENDVVHLFILTEDKSEFSTKDRINMVKLGTKHLKNVLIHEAGKYIISSATFPSYFIKEQ
CCCCEEEEEEEECCCHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCHHHHHHH
KNITKAHAYLDLTLFCEYISKALNIKYRYVGEEPFSNLTNEYNQYMKEILPKHNIQVIEV
HCHHHHHHHHHHHHHHHHHHHHHCEEEEEECCCHHHHHHHHHHHHHHHHCCCCCEEEEEE
KRLKEDGQAISASSVRSFLKEGNLEKVESLVPKTTFDYLLNISKK
EHHHHCCCEECHHHHHHHHHCCCHHHHHHHCCCHHHHHHHCCCCC
>Mature Secondary Structure 
SEWNYENTFEEELTFFSFNPQINKKYKFQVEEFLKKENLRFVKSINFTVCVFNNKELIA
CCCCCCCCHHHCCEEEEECCCCCCCHHHHHHHHHHHCCCCEEEECCEEEEEECCCEEEE
TGSLDEYILKCFAVRSDYRKKGISEKILRILTEKAFENGETHLFIYTKPKNSKLFESLGY
ECCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHCCH
HQLINIPNLVSLLENKSTGIRTYILNLQKKSYLQGVKVASIVMNCNPFTNGHKYLIEKAS
HHHCCCHHHHHHHHCCCCCEEEEEEECHHHHHHHHHEEEHEEEECCCCCCCHHHHHHHCC
KENDVVHLFILTEDKSEFSTKDRINMVKLGTKHLKNVLIHEAGKYIISSATFPSYFIKEQ
CCCCEEEEEEEECCCHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCHHHHHHH
KNITKAHAYLDLTLFCEYISKALNIKYRYVGEEPFSNLTNEYNQYMKEILPKHNIQVIEV
HCHHHHHHHHHHHHHHHHHHHHHCEEEEEECCCHHHHHHHHHHHHHHHHCCCCCEEEEEE
KRLKEDGQAISASSVRSFLKEGNLEKVESLVPKTTFDYLLNISKK
EHHHHCCCEECHHHHHHHHHCCCHHHHHHHCCCHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503 [H]