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The map label for this gene is 18309857

Identifier: 18309857

GI number: 18309857

Start: 1075490

End: 1076617

Strand: Direct

Name: 18309857

Synonym: CPE0875

Alternate gene names: NA

Gene position: 1075490-1076617 (Clockwise)

Preceding gene: 18309856

Following gene: 18309858

Centisome position: 35.48

GC content: 33.69

Gene sequence:

>1128_bases
ATGGCAGATCAAAGATTAAATAAGTTAGCTAAACTGCTTGTAAATTATTCAACAGGAGTTAAGGAAGGGAACTTTGTTTT
TGTATCTTGTAATGAGGTTGCAAATCCTTGGCTTACTGAGGTAGTAAAGGAAGCTACTAAGGCAGGAGCTCATGTTGAGT
ATATTTTAGAATCAGAAGAAGCTAAGGAGGCAAGACTTAAATTTTCTACAAAGGATCAATTATTATCAGGAAATTTAATA
ATGGAAACTATGCTTGAAAAGGCAGATGTTTGGTTAAGTGCATGGGGAGCTAGAAATACTAGAGCCTTTAGCAATATAGA
TTCAGAAAAAATAAAAGATAGCAGAGCTGGAGAAAAGGGATGGAGAAAGTTCTATTCAGGAAGAATGGGAGATGGCTCTT
TAAGATGGTGTGGAACTCAATTTCCTACATATGCAGATGCACAGGAAGCTTCAATGAGTTTTAGTGAATATGAAGATTTT
GTTTATGGAGCAGGACTTTTAGACCATGAAGATCCTGTAGCAGAATGGAATAGAGTAAGCAAAGAACAAGAAAGATGGGT
TAAATATTTAGATACTAAAAAAGAACTTCATATTTTAGCAGAAGAAACTGATATTAAGGTCTCAGTAGAGGGAAGAAAGT
GGATAAATTGTGATGGTAGAGTAAACTTTCCAGATGGTGAAATATTTACATCACCAGTTGAAAATAAGATAAATGGACAT
ATAACTTTTTCATTCCCAGGTATTTATGCAGGAAAGGAAATAGAGGGTATAGAGCTTGAAGTTAAAGATGGTAAAGTTGT
TTCATATAAAGCTAAAAAAGGAGAAGATTTATTAAAGGCTTTATTAGAAACTGATGAAGGAGCAAGCCATTTTGGAGAAG
TAGCTATAGGTACAAACTATGGAATTAAGAAGTTTACTAGAAATATGCTATTTGATGAGAAAATAGGAGGAACAGTTCAT
ATGGCTATAGGAGATTCTATGCCAGAGGCTGGTGGTAAAAATAGATCATCACTTCATTGGGACATGCTTTGTGACATGAG
AAATGGTGGAAGAATATATGCAGATGGAGAACTTTTCTATGAAAATGGAGAGTTTAAAAAAGAAATATTAGAAAAATATA
ATCTTTAA

Upstream 100 bases:

>100_bases
AACTAGTTTTAAAAATTTATTGTTATTAATAAAAAATAGTAAGTTAAAATAGAATTCAAAAATTAAAATATATAAATTTG
TATGTTTAGGAGGTATATGT

Downstream 100 bases:

>100_bases
TATTATATATAAATTATAGAATAATAATTAAATTAGGGGATGAAGAGACTCATCTCCTAATTTAATTCTAGTTGAATTTT
AAAATAATGGGAGTATAAGA

Product: metalloprotease family protein

Products: NA

Alternate protein names: Aminopeptidase II; AP-II [H]

Number of amino acids: Translated: 375; Mature: 374

Protein sequence:

>375_residues
MADQRLNKLAKLLVNYSTGVKEGNFVFVSCNEVANPWLTEVVKEATKAGAHVEYILESEEAKEARLKFSTKDQLLSGNLI
METMLEKADVWLSAWGARNTRAFSNIDSEKIKDSRAGEKGWRKFYSGRMGDGSLRWCGTQFPTYADAQEASMSFSEYEDF
VYGAGLLDHEDPVAEWNRVSKEQERWVKYLDTKKELHILAEETDIKVSVEGRKWINCDGRVNFPDGEIFTSPVENKINGH
ITFSFPGIYAGKEIEGIELEVKDGKVVSYKAKKGEDLLKALLETDEGASHFGEVAIGTNYGIKKFTRNMLFDEKIGGTVH
MAIGDSMPEAGGKNRSSLHWDMLCDMRNGGRIYADGELFYENGEFKKEILEKYNL

Sequences:

>Translated_375_residues
MADQRLNKLAKLLVNYSTGVKEGNFVFVSCNEVANPWLTEVVKEATKAGAHVEYILESEEAKEARLKFSTKDQLLSGNLI
METMLEKADVWLSAWGARNTRAFSNIDSEKIKDSRAGEKGWRKFYSGRMGDGSLRWCGTQFPTYADAQEASMSFSEYEDF
VYGAGLLDHEDPVAEWNRVSKEQERWVKYLDTKKELHILAEETDIKVSVEGRKWINCDGRVNFPDGEIFTSPVENKINGH
ITFSFPGIYAGKEIEGIELEVKDGKVVSYKAKKGEDLLKALLETDEGASHFGEVAIGTNYGIKKFTRNMLFDEKIGGTVH
MAIGDSMPEAGGKNRSSLHWDMLCDMRNGGRIYADGELFYENGEFKKEILEKYNL
>Mature_374_residues
ADQRLNKLAKLLVNYSTGVKEGNFVFVSCNEVANPWLTEVVKEATKAGAHVEYILESEEAKEARLKFSTKDQLLSGNLIM
ETMLEKADVWLSAWGARNTRAFSNIDSEKIKDSRAGEKGWRKFYSGRMGDGSLRWCGTQFPTYADAQEASMSFSEYEDFV
YGAGLLDHEDPVAEWNRVSKEQERWVKYLDTKKELHILAEETDIKVSVEGRKWINCDGRVNFPDGEIFTSPVENKINGHI
TFSFPGIYAGKEIEGIELEVKDGKVVSYKAKKGEDLLKALLETDEGASHFGEVAIGTNYGIKKFTRNMLFDEKIGGTVHM
AIGDSMPEAGGKNRSSLHWDMLCDMRNGGRIYADGELFYENGEFKKEILEKYNL

Specific function: Broad specificity metal-dependent exopeptidase, releasing all N-terminal amino acids [H]

COG id: COG2309

COG function: function code E; Leucyl aminopeptidase (aminopeptidase T)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M29 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000787 [H]

Pfam domain/function: PF02073 Peptidase_M29 [H]

EC number: NA

Molecular weight: Translated: 42322; Mature: 42191

Theoretical pI: Translated: 5.00; Mature: 5.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADQRLNKLAKLLVNYSTGVKEGNFVFVSCNEVANPWLTEVVKEATKAGAHVEYILESEE
CCHHHHHHHHHHHHHHCCCCCCCCEEEEECHHHCCHHHHHHHHHHHHCCCEEEEEECCCH
AKEARLKFSTKDQLLSGNLIMETMLEKADVWLSAWGARNTRAFSNIDSEKIKDSRAGEKG
HHHHHEEECCHHHHHCCCHHHHHHHHHHHHHEEECCCCCCCHHHCCCHHHHHHHCCCHHH
WRKFYSGRMGDGSLRWCGTQFPTYADAQEASMSFSEYEDFVYGAGLLDHEDPVAEWNRVS
HHHHHCCCCCCCCEEEECCCCCCCCCHHHHHCCHHHHHHHHHCCCCCCCCCHHHHHHHCC
KEQERWVKYLDTKKELHILAEETDIKVSVEGRKWINCDGRVNFPDGEIFTSPVENKINGH
HHHHHHHHHHCCCCCEEEEEECCCEEEEECCCEEECCCCEEECCCCCEECCCCCCCCCCE
ITFSFPGIYAGKEIEGIELEVKDGKVVSYKAKKGEDLLKALLETDEGASHFGEVAIGTNY
EEEECCCEECCCCCCCEEEEEECCEEEEEECCCCHHHHHHHHHCCCCCHHHCCEEECCCC
GIKKFTRNMLFDEKIGGTVHMAIGDSMPEAGGKNRSSLHWDMLCDMRNGGRIYADGELFY
CHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCEEEEEEEEECCCCEEEECCEEEE
ENGEFKKEILEKYNL
ECCCHHHHHHHHHCC
>Mature Secondary Structure 
ADQRLNKLAKLLVNYSTGVKEGNFVFVSCNEVANPWLTEVVKEATKAGAHVEYILESEE
CHHHHHHHHHHHHHHCCCCCCCCEEEEECHHHCCHHHHHHHHHHHHCCCEEEEEECCCH
AKEARLKFSTKDQLLSGNLIMETMLEKADVWLSAWGARNTRAFSNIDSEKIKDSRAGEKG
HHHHHEEECCHHHHHCCCHHHHHHHHHHHHHEEECCCCCCCHHHCCCHHHHHHHCCCHHH
WRKFYSGRMGDGSLRWCGTQFPTYADAQEASMSFSEYEDFVYGAGLLDHEDPVAEWNRVS
HHHHHCCCCCCCCEEEECCCCCCCCCHHHHHCCHHHHHHHHHCCCCCCCCCHHHHHHHCC
KEQERWVKYLDTKKELHILAEETDIKVSVEGRKWINCDGRVNFPDGEIFTSPVENKINGH
HHHHHHHHHHCCCCCEEEEEECCCEEEEECCCEEECCCCEEECCCCCEECCCCCCCCCCE
ITFSFPGIYAGKEIEGIELEVKDGKVVSYKAKKGEDLLKALLETDEGASHFGEVAIGTNY
EEEECCCEECCCCCCCEEEEEECCEEEEEECCCCHHHHHHHHHCCCCCHHHCCEEECCCC
GIKKFTRNMLFDEKIGGTVHMAIGDSMPEAGGKNRSSLHWDMLCDMRNGGRIYADGELFY
CHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCEEEEEEEEECCCCEEEECCEEEE
ENGEFKKEILEKYNL
ECCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9362117; 938681 [H]