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The map label for this gene is fhuG [H]

Identifier: 18309794

GI number: 18309794

Start: 996104

End: 997117

Strand: Direct

Name: fhuG [H]

Synonym: CPE0812

Alternate gene names: 18309794

Gene position: 996104-997117 (Clockwise)

Preceding gene: 18309793

Following gene: 18309795

Centisome position: 32.86

GC content: 28.9

Gene sequence:

>1014_bases
ATGAATATAAAAAAGAATCATAAATTTATATGGGTAACGGGAATTTTAATAGGTTTAATTTTTATTACCTTTTTAATAAG
TTTAAACATGGGTTCACTTTCAATAGAGCCAGGAGAAGTTATTAAAACTTTAATTGGACAAGGTACAAAAAGTAATGAAA
TAGCTATATTTAAGCTTAGACTTCCTAGAATAGTCATAGGAATATTAGTAGGAACAGCTCTAGCAACTGCAGGTACAATC
CTGCAAGGGGTTACTAAAAATGATTTAGCTGATTCAGGAATACTTGGAATAAATTCAGGAGCTGCCTTATTTGTTGTAGT
ATATATATATATAATGAATGGAAATGTATATGATGGTGTAAGTAATTTAACTATTTTTACTATGCCTATAGTAGCTTTAA
GTGGAGCTATATTTGGAGCATTTTTAATATACATATTAGCATGGAAGAATGGAATAAATTCATCAAGACTATTATTAATA
GGTATAGGTATAAATATAGCTTTTACATCCTTATTAACAATATTTCAGTTAAGATTTACTACTCAAGAATTTAATAGAGT
TATGGCTTGGATATCAGGAAGTATATGGGGAGCAAGTTGGAAATATGTATTAGCAATATTACCATTTATAATTATATTTA
TGGCTTTAACTATATATAAATCAAGATATTTAGATGGATTAAATTTAGGAGACGAAGTTGCCACAGGTATAGGGATTGAA
GTGGAAAAAGAAAGAAGAAAACTAATTATATATGCAGTTATATTAGCAGGGGTAGCTACATCAGTTGCAGGTAGCATAGG
TTTCCTAGGTTTAGTATCTCCTCATATAGCAAGAAAATTAATAGGGCCAAAGCATAAGAAATTAATTCCTGTATCAGCCC
TTATTGGAAGTTTAATATTATTAGTGTCAGATACTATAGCAAGAAATTTAATTGCACCAATGGAAATGCCAGTAGGTATA
ATCGTATCTATAATAGGAGTTCCATATTTTATTTATTTAATGTTATCAAAATAG

Upstream 100 bases:

>100_bases
GATTATAAACCCTCCTTATGAAACACCAATAGGATCTTTAACTGCCTTATTAGGAGTGCCAGTGTTTATATACTTAGTTA
GAAAGGGAGGTAAGTAATTT

Downstream 100 bases:

>100_bases
ATATTTATATACCTAGGCATAAATTAATATTTATAAATAAAAACGAAAGTAGAAGGAGATAATTATGAATTGTATAACTA
CTGATAATTTAAATATTTCA

Product: ferrichrome ABC transporter

Products: ADP; phosphate; iron dicitrate [Cytoplasm] [C]

Alternate protein names: Ferric hydroxamate uptake protein G; Ferrichrome transport system permease protein fhuG; Iron(III)-hydroxamate import system permease protein fhuG [H]

Number of amino acids: Translated: 337; Mature: 337

Protein sequence:

>337_residues
MNIKKNHKFIWVTGILIGLIFITFLISLNMGSLSIEPGEVIKTLIGQGTKSNEIAIFKLRLPRIVIGILVGTALATAGTI
LQGVTKNDLADSGILGINSGAALFVVVYIYIMNGNVYDGVSNLTIFTMPIVALSGAIFGAFLIYILAWKNGINSSRLLLI
GIGINIAFTSLLTIFQLRFTTQEFNRVMAWISGSIWGASWKYVLAILPFIIIFMALTIYKSRYLDGLNLGDEVATGIGIE
VEKERRKLIIYAVILAGVATSVAGSIGFLGLVSPHIARKLIGPKHKKLIPVSALIGSLILLVSDTIARNLIAPMEMPVGI
IVSIIGVPYFIYLMLSK

Sequences:

>Translated_337_residues
MNIKKNHKFIWVTGILIGLIFITFLISLNMGSLSIEPGEVIKTLIGQGTKSNEIAIFKLRLPRIVIGILVGTALATAGTI
LQGVTKNDLADSGILGINSGAALFVVVYIYIMNGNVYDGVSNLTIFTMPIVALSGAIFGAFLIYILAWKNGINSSRLLLI
GIGINIAFTSLLTIFQLRFTTQEFNRVMAWISGSIWGASWKYVLAILPFIIIFMALTIYKSRYLDGLNLGDEVATGIGIE
VEKERRKLIIYAVILAGVATSVAGSIGFLGLVSPHIARKLIGPKHKKLIPVSALIGSLILLVSDTIARNLIAPMEMPVGI
IVSIIGVPYFIYLMLSK
>Mature_337_residues
MNIKKNHKFIWVTGILIGLIFITFLISLNMGSLSIEPGEVIKTLIGQGTKSNEIAIFKLRLPRIVIGILVGTALATAGTI
LQGVTKNDLADSGILGINSGAALFVVVYIYIMNGNVYDGVSNLTIFTMPIVALSGAIFGAFLIYILAWKNGINSSRLLLI
GIGINIAFTSLLTIFQLRFTTQEFNRVMAWISGSIWGASWKYVLAILPFIIIFMALTIYKSRYLDGLNLGDEVATGIGIE
VEKERRKLIIYAVILAGVATSVAGSIGFLGLVSPHIARKLIGPKHKKLIPVSALIGSLILLVSDTIARNLIAPMEMPVGI
IVSIIGVPYFIYLMLSK

Specific function: Part of the ABC transporter complex fhuBGCD involved in iron(3+)-hydroxamate import. Responsible for the translocation of the substrate across the membrane [H]

COG id: COG0609

COG function: function code P; ABC-type Fe3+-siderophore transport system, permease component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790740, Length=321, Percent_Identity=34.8909657320872, Blast_Score=186, Evalue=2e-48,
Organism=Escherichia coli, GI1786347, Length=278, Percent_Identity=34.5323741007194, Blast_Score=140, Evalue=2e-34,
Organism=Escherichia coli, GI1786804, Length=310, Percent_Identity=30.6451612903226, Blast_Score=135, Evalue=4e-33,
Organism=Escherichia coli, GI1790741, Length=341, Percent_Identity=28.1524926686217, Blast_Score=129, Evalue=3e-31,
Organism=Escherichia coli, GI1788004, Length=307, Percent_Identity=30.2931596091205, Blast_Score=128, Evalue=4e-31,
Organism=Escherichia coli, GI1786805, Length=313, Percent_Identity=29.073482428115, Blast_Score=107, Evalue=1e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000522 [H]

Pfam domain/function: PF01032 FecCD [H]

EC number: NA

Molecular weight: Translated: 36439; Mature: 36439

Theoretical pI: Translated: 10.36; Mature: 10.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIKKNHKFIWVTGILIGLIFITFLISLNMGSLSIEPGEVIKTLIGQGTKSNEIAIFKLR
CCCCCCCCEEEHHHHHHHHHHHHHHHHCCCCCEECCHHHHHHHHHCCCCCCCCEEEEEEE
LPRIVIGILVGTALATAGTILQGVTKNDLADSGILGINSGAALFVVVYIYIMNGNVYDGV
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEECCCCHHHHHHHHHHHCCCCEECCC
SNLTIFTMPIVALSGAIFGAFLIYILAWKNGINSSRLLLIGIGINIAFTSLLTIFQLRFT
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECHHHHHHHHHHHHHHHHH
TQEFNRVMAWISGSIWGASWKYVLAILPFIIIFMALTIYKSRYLDGLNLGDEVATGIGIE
HHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHCCCCE
VEKERRKLIIYAVILAGVATSVAGSIGFLGLVSPHIARKLIGPKHKKLIPVSALIGSLIL
EEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHCCCCCCCEEEHHHHHHHHHH
LVSDTIARNLIAPMEMPVGIIVSIIGVPYFIYLMLSK
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNIKKNHKFIWVTGILIGLIFITFLISLNMGSLSIEPGEVIKTLIGQGTKSNEIAIFKLR
CCCCCCCCEEEHHHHHHHHHHHHHHHHCCCCCEECCHHHHHHHHHCCCCCCCCEEEEEEE
LPRIVIGILVGTALATAGTILQGVTKNDLADSGILGINSGAALFVVVYIYIMNGNVYDGV
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEECCCCHHHHHHHHHHHCCCCEECCC
SNLTIFTMPIVALSGAIFGAFLIYILAWKNGINSSRLLLIGIGINIAFTSLLTIFQLRFT
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECHHHHHHHHHHHHHHHHH
TQEFNRVMAWISGSIWGASWKYVLAILPFIIIFMALTIYKSRYLDGLNLGDEVATGIGIE
HHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHCCCCE
VEKERRKLIIYAVILAGVATSVAGSIGFLGLVSPHIARKLIGPKHKKLIPVSALIGSLIL
EEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHCCCCCCCEEEHHHHHHHHHH
LVSDTIARNLIAPMEMPVGIIVSIIGVPYFIYLMLSK
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; iron dicitrate [Periplasm]; H2O [C]

Specific reaction: ATP + iron dicitrate [Periplasm] + H2O = ADP + phosphate + iron dicitrate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9639930; 9384377 [H]