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The map label for this gene is nanI

Identifier: 18309707

GI number: 18309707

Start: 900997

End: 903081

Strand: Direct

Name: nanI

Synonym: CPE0725

Alternate gene names: NA

Gene position: 900997-903081 (Clockwise)

Preceding gene: 18309706

Following gene: 18309708

Centisome position: 29.72

GC content: 28.63

Gene sequence:

>2085_bases
ATGAATTACAAAGGGATAACTTTAATTTTAACAGCTGCTATGGTTATAAGTGGTGGTAATTATGTATTGGTTAAAGGAAG
TACTTTAGACTCAGGGAAAAATAATAGTGGGTATGAGATTAAAGTAAATAATAGTGAAAGTTTAAGTTCACTAGGAGAAT
ATAAGGATATAAATTTAGAAAGTTCAAATGCTTCTAATATTACTTATGATTTAGAAAAATATAAAAATTTAGATGAAGGT
ACTATTGTTGTAAGATTTAATTCTAAAGATTCTAAAATACAAAGCTTATTAGGAATAAGTAATAGCAAAACTAAAAATGG
ATATTTTAATTTTTATGTTACTAATTCAAGAGTTGGTTTTGAGCTTAGAAATCAAAAAAATGAGGGAAATACACAAAGTG
GAACTGAAAATCTAGTACATATGTATAAAGACGTTGCTTTAAATGATGGTGATAATACTGTTGCCTTAAAGATTGAAAAA
AACAAAGGTTATAAGCTTTTCCTTAATGGAAAAATCATAAAAGAAGTTAAAGATACAAATACAAAGTTTTTAAATAATAT
AGAAAATTTAGATAGTGCTTTTATTGGAAAAACTAATAGATATGGACAATCTAATGAATATAATTTTAAGGGCAATATAG
GTTTTATGAATATATATAATGAACCTTTAGGCGATGATTATTTACTTAGTAAGACTGGAGAGACAAAAGCTAAAGAAGAA
GTTCTTGTAGAGGGAGCTGTAAAGACAGAGCCAGTTGATTTATTTCATCCAGGATTTTTAAATTCTAGTAATTACAGAAT
ACCAGCCTTATTTAAAACAAAAGAAGGAACTTTAATAGCTTCAATAGATGCAAGAAGACATGGTGGGGCCGATGCTCCTA
ACAATGATATAGATACAGCAGTTAGAAGAAGTGAAGATGGAGGGAAAACTTGGGATGAAGGACAAATAATAATGGACTAT
CCTGATAAATCCTCTGTTATAGATACAACTTTAATTCAAGATGATGAAACAGGAAGAATATTCTTGTTGGTAACTCATTT
CCCTTCAAAATATGGTTTTTGGAATGCTGGATTAGGAAGTGGATTTAAAAATATTGATGGAAAAGAATATTTATGTCTTT
ACGATTCATCAGGTAAAGAATTTACTGTAAGAGAAAATGTAGTATATGACAAAGATGGCAATAAAACAGAATATACAACA
AATGCTTTAGGAGATTTATTTAAAAATGGAACTAAGATAGATAATATAAATTCTAGTACAGCACCTTTAAAAGCAAAAGG
GACAAGCTATATAAATCTTGTATATAGTGATGATGATGGAAAGACTTGGAGTGAGCCACAAAATATTAATTTCCAAGTTA
AAAAGGATTGGATGAAGTTTTTAGGAATAGCTCCAGGTAGAGGAATACAAATAAAAAATGGAGAACATAAAGGAAGAATA
GTAGTTCCTGTTTACTATACAAATGAAAAAGGTAAACAATCTAGTGCTGTAATATATAGTGATGATAGTGGTAAGAATTG
GACAATAGGAGAATCTCCAAATGATAATAGAAAATTAGAAAATGGAAAAATAATAAATTCTAAAACCTTATCAGATGATG
CACCTCAATTAACTGAATGTCAAGTAGTAGAAATGCCAAATGGTCAACTAAAATTATTTATGAGAAATTTAAGTGGATAT
TTAAATATTGCTACAAGTTTTGATGGGGGAGCTACTTGGGACGAGACAGTAGAGAAAGATACTAATGTTTTAGAGCCATA
TTGCCAATTAAGTGTTATAAATTATAGTCAAAAGATAGATGGAAAGGATGCTGTTATCTTCTCAAATCCAAACGCAAGAA
GTAGATCAAATGGTACTGTGAGAATTGGATTGATTAATCAAGTTGGAACATATGAAAATGGTGAACCTAAATATGAATTT
GATTGGAAATATAATAAATTAGTTAAACCAGGGTATTATGCTTATTCTTGTTTAACAGAATTAAGCAATGGAAATATTGG
ATTATTATATGAGGGTACACCAAGTGAAGAAATGTCTTATATTGAAATGAATTTAAAATATTTAGAGAGTGGAGCTAATA
AATAA

Upstream 100 bases:

>100_bases
AGTTACAAATACAATAATAAAAATTTTACTTCGTATGTCATAGTATTTTAAATTAATACTATTTCAAAATAATAAAAAAT
TATTTATGGGAGGATGTAAA

Downstream 100 bases:

>100_bases
GAAATTATTAAAAATATTATTTTATGGTTTGAAAGGGGTAAAAGATTATGAAAAAGATATGGAAGTATGGGGTACTACTT
GCATTACCATTAGTTTTAGC

Product: exo-alpha-sialidase

Products: NA

Alternate protein names: Neuraminidase [H]

Number of amino acids: Translated: 694; Mature: 694

Protein sequence:

>694_residues
MNYKGITLILTAAMVISGGNYVLVKGSTLDSGKNNSGYEIKVNNSESLSSLGEYKDINLESSNASNITYDLEKYKNLDEG
TIVVRFNSKDSKIQSLLGISNSKTKNGYFNFYVTNSRVGFELRNQKNEGNTQSGTENLVHMYKDVALNDGDNTVALKIEK
NKGYKLFLNGKIIKEVKDTNTKFLNNIENLDSAFIGKTNRYGQSNEYNFKGNIGFMNIYNEPLGDDYLLSKTGETKAKEE
VLVEGAVKTEPVDLFHPGFLNSSNYRIPALFKTKEGTLIASIDARRHGGADAPNNDIDTAVRRSEDGGKTWDEGQIIMDY
PDKSSVIDTTLIQDDETGRIFLLVTHFPSKYGFWNAGLGSGFKNIDGKEYLCLYDSSGKEFTVRENVVYDKDGNKTEYTT
NALGDLFKNGTKIDNINSSTAPLKAKGTSYINLVYSDDDGKTWSEPQNINFQVKKDWMKFLGIAPGRGIQIKNGEHKGRI
VVPVYYTNEKGKQSSAVIYSDDSGKNWTIGESPNDNRKLENGKIINSKTLSDDAPQLTECQVVEMPNGQLKLFMRNLSGY
LNIATSFDGGATWDETVEKDTNVLEPYCQLSVINYSQKIDGKDAVIFSNPNARSRSNGTVRIGLINQVGTYENGEPKYEF
DWKYNKLVKPGYYAYSCLTELSNGNIGLLYEGTPSEEMSYIEMNLKYLESGANK

Sequences:

>Translated_694_residues
MNYKGITLILTAAMVISGGNYVLVKGSTLDSGKNNSGYEIKVNNSESLSSLGEYKDINLESSNASNITYDLEKYKNLDEG
TIVVRFNSKDSKIQSLLGISNSKTKNGYFNFYVTNSRVGFELRNQKNEGNTQSGTENLVHMYKDVALNDGDNTVALKIEK
NKGYKLFLNGKIIKEVKDTNTKFLNNIENLDSAFIGKTNRYGQSNEYNFKGNIGFMNIYNEPLGDDYLLSKTGETKAKEE
VLVEGAVKTEPVDLFHPGFLNSSNYRIPALFKTKEGTLIASIDARRHGGADAPNNDIDTAVRRSEDGGKTWDEGQIIMDY
PDKSSVIDTTLIQDDETGRIFLLVTHFPSKYGFWNAGLGSGFKNIDGKEYLCLYDSSGKEFTVRENVVYDKDGNKTEYTT
NALGDLFKNGTKIDNINSSTAPLKAKGTSYINLVYSDDDGKTWSEPQNINFQVKKDWMKFLGIAPGRGIQIKNGEHKGRI
VVPVYYTNEKGKQSSAVIYSDDSGKNWTIGESPNDNRKLENGKIINSKTLSDDAPQLTECQVVEMPNGQLKLFMRNLSGY
LNIATSFDGGATWDETVEKDTNVLEPYCQLSVINYSQKIDGKDAVIFSNPNARSRSNGTVRIGLINQVGTYENGEPKYEF
DWKYNKLVKPGYYAYSCLTELSNGNIGLLYEGTPSEEMSYIEMNLKYLESGANK
>Mature_694_residues
MNYKGITLILTAAMVISGGNYVLVKGSTLDSGKNNSGYEIKVNNSESLSSLGEYKDINLESSNASNITYDLEKYKNLDEG
TIVVRFNSKDSKIQSLLGISNSKTKNGYFNFYVTNSRVGFELRNQKNEGNTQSGTENLVHMYKDVALNDGDNTVALKIEK
NKGYKLFLNGKIIKEVKDTNTKFLNNIENLDSAFIGKTNRYGQSNEYNFKGNIGFMNIYNEPLGDDYLLSKTGETKAKEE
VLVEGAVKTEPVDLFHPGFLNSSNYRIPALFKTKEGTLIASIDARRHGGADAPNNDIDTAVRRSEDGGKTWDEGQIIMDY
PDKSSVIDTTLIQDDETGRIFLLVTHFPSKYGFWNAGLGSGFKNIDGKEYLCLYDSSGKEFTVRENVVYDKDGNKTEYTT
NALGDLFKNGTKIDNINSSTAPLKAKGTSYINLVYSDDDGKTWSEPQNINFQVKKDWMKFLGIAPGRGIQIKNGEHKGRI
VVPVYYTNEKGKQSSAVIYSDDSGKNWTIGESPNDNRKLENGKIINSKTLSDDAPQLTECQVVEMPNGQLKLFMRNLSGY
LNIATSFDGGATWDETVEKDTNVLEPYCQLSVINYSQKIDGKDAVIFSNPNARSRSNGTVRIGLINQVGTYENGEPKYEF
DWKYNKLVKPGYYAYSCLTELSNGNIGLLYEGTPSEEMSYIEMNLKYLESGANK

Specific function: Sialidases have been suggested to be pathogenic factors in microbial infections [H]

COG id: COG4409

COG function: function code G; Neuraminidase (sialidase)

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 F5/8 type C domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002860
- InterPro:   IPR000421
- InterPro:   IPR008985
- InterPro:   IPR013320
- InterPro:   IPR008979
- InterPro:   IPR004124
- InterPro:   IPR011040 [H]

Pfam domain/function: PF02012 BNR; PF00754 F5_F8_type_C; PF02973 Sialidase [H]

EC number: =3.2.1.18 [H]

Molecular weight: Translated: 77315; Mature: 77315

Theoretical pI: Translated: 5.23; Mature: 5.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNYKGITLILTAAMVISGGNYVLVKGSTLDSGKNNSGYEIKVNNSESLSSLGEYKDINLE
CCCCCEEHEEEEEHHEECCCEEEEECCCCCCCCCCCCEEEEECCCHHHHHCCCCEECEEC
SSNASNITYDLEKYKNLDEGTIVVRFNSKDSKIQSLLGISNSKTKNGYFNFYVTNSRVGF
CCCCCCEEEEHHHHCCCCCCEEEEEECCCHHHHHHHHCCCCCCCCCCEEEEEEECCEEEE
ELRNQKNEGNTQSGTENLVHMYKDVALNDGDNTVALKIEKNKGYKLFLNGKIIKEVKDTN
EEECCCCCCCCCCCHHHHHHHHHHHEECCCCCEEEEEEECCCCEEEEECCEEEEHHHCCC
TKFLNNIENLDSAFIGKTNRYGQSNEYNFKGNIGFMNIYNEPLGDDYLLSKTGETKAKEE
HHHHHHHHHHHHHHCCCCCCCCCCCCCEEECCEEEEEECCCCCCCCEEEECCCCCCCHHH
VLVEGAVKTEPVDLFHPGFLNSSNYRIPALFKTKEGTLIASIDARRHGGADAPNNDIDTA
HEEECCCCCCCCEEECCCCCCCCCEEEEEEEEECCCCEEEEECCCCCCCCCCCCCCHHHH
VRRSEDGGKTWDEGQIIMDYPDKSSVIDTTLIQDDETGRIFLLVTHFPSKYGFWNAGLGS
HHCCCCCCCCCCCCEEEEECCCCCCEEEEEEEECCCCCEEEEEEEECCCCCCEEECCCCC
GFKNIDGKEYLCLYDSSGKEFTVRENVVYDKDGNKTEYTTNALGDLFKNGTKIDNINSST
CCCCCCCCEEEEEECCCCCEEEEECCEEECCCCCCCEEEHHHHHHHHHCCCEECCCCCCC
APLKAKGTSYINLVYSDDDGKTWSEPQNINFQVKKDWMKFLGIAPGRGIQIKNGEHKGRI
CCEEECCCEEEEEEEECCCCCCCCCCCCCCEEEHHHHHHHHCCCCCCCEEEECCCCCCEE
VVPVYYTNEKGKQSSAVIYSDDSGKNWTIGESPNDNRKLENGKIINSKTLSDDAPQLTEC
EEEEEEECCCCCCCCEEEEECCCCCEEECCCCCCCCCCCCCCEEEECCCCCCCCCCCCCE
QVVEMPNGQLKLFMRNLSGYLNIATSFDGGATWDETVEKDTNVLEPYCQLSVINYSQKID
EEEECCCCCEEEEEECCCCEEEEEEECCCCCCCHHHHHCCCCCCCCCCEEEEEECCCCCC
GKDAVIFSNPNARSRSNGTVRIGLINQVGTYENGEPKYEFDWKYNKLVKPGYYAYSCLTE
CCCEEEECCCCCCCCCCCEEEEEEEECCCCCCCCCCCEEECCCCCCCCCCCHHHHHHHHH
LSNGNIGLLYEGTPSEEMSYIEMNLKYLESGANK
HCCCCEEEEECCCCCCCEEEEEEEHHHHHCCCCC
>Mature Secondary Structure
MNYKGITLILTAAMVISGGNYVLVKGSTLDSGKNNSGYEIKVNNSESLSSLGEYKDINLE
CCCCCEEHEEEEEHHEECCCEEEEECCCCCCCCCCCCEEEEECCCHHHHHCCCCEECEEC
SSNASNITYDLEKYKNLDEGTIVVRFNSKDSKIQSLLGISNSKTKNGYFNFYVTNSRVGF
CCCCCCEEEEHHHHCCCCCCEEEEEECCCHHHHHHHHCCCCCCCCCCEEEEEEECCEEEE
ELRNQKNEGNTQSGTENLVHMYKDVALNDGDNTVALKIEKNKGYKLFLNGKIIKEVKDTN
EEECCCCCCCCCCCHHHHHHHHHHHEECCCCCEEEEEEECCCCEEEEECCEEEEHHHCCC
TKFLNNIENLDSAFIGKTNRYGQSNEYNFKGNIGFMNIYNEPLGDDYLLSKTGETKAKEE
HHHHHHHHHHHHHHCCCCCCCCCCCCCEEECCEEEEEECCCCCCCCEEEECCCCCCCHHH
VLVEGAVKTEPVDLFHPGFLNSSNYRIPALFKTKEGTLIASIDARRHGGADAPNNDIDTA
HEEECCCCCCCCEEECCCCCCCCCEEEEEEEEECCCCEEEEECCCCCCCCCCCCCCHHHH
VRRSEDGGKTWDEGQIIMDYPDKSSVIDTTLIQDDETGRIFLLVTHFPSKYGFWNAGLGS
HHCCCCCCCCCCCCEEEEECCCCCCEEEEEEEECCCCCEEEEEEEECCCCCCEEECCCCC
GFKNIDGKEYLCLYDSSGKEFTVRENVVYDKDGNKTEYTTNALGDLFKNGTKIDNINSST
CCCCCCCCEEEEEECCCCCEEEEECCEEECCCCCCCEEEHHHHHHHHHCCCEECCCCCCC
APLKAKGTSYINLVYSDDDGKTWSEPQNINFQVKKDWMKFLGIAPGRGIQIKNGEHKGRI
CCEEECCCEEEEEEEECCCCCCCCCCCCCCEEEHHHHHHHHCCCCCCCEEEECCCCCCEE
VVPVYYTNEKGKQSSAVIYSDDSGKNWTIGESPNDNRKLENGKIINSKTLSDDAPQLTEC
EEEEEEECCCCCCCCEEEEECCCCCEEECCCCCCCCCCCCCCEEEECCCCCCCCCCCCCE
QVVEMPNGQLKLFMRNLSGYLNIATSFDGGATWDETVEKDTNVLEPYCQLSVINYSQKID
EEEECCCCCEEEEEECCCCEEEEEEECCCCCCCHHHHHCCCCCCCCCCEEEEEECCCCCC
GKDAVIFSNPNARSRSNGTVRIGLINQVGTYENGEPKYEFDWKYNKLVKPGYYAYSCLTE
CCCEEEECCCCCCCCCCCEEEEEEEECCCCCCCCCCCEEECCCCCCCCCCCHHHHHHHHH
LSNGNIGLLYEGTPSEEMSYIEMNLKYLESGANK
HCCCCEEEEECCCCCCCEEEEEEEHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2034213 [H]