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The map label for this gene is helD [H]

Identifier: 18309581

GI number: 18309581

Start: 748076

End: 750196

Strand: Direct

Name: helD [H]

Synonym: CPE0599

Alternate gene names: 18309581

Gene position: 748076-750196 (Clockwise)

Preceding gene: 18309580

Following gene: 18309582

Centisome position: 24.68

GC content: 26.97

Gene sequence:

>2121_bases
ATGACTGATAAAAAAGATATAGAATTTTTAGTTGAAGAGAAAAAATTAGAGGAAGTTTCTAATATATTAAATGAAGAAAT
GCTTTCATATATAAATAAAAGAAAATTTGTAACACAATATATATTAGATTATAGAAAAAATGCAGTTGAAGAATATAAAG
ATGATGAAGATAAATTAATAGAGTACTTTGACCATGAAAGATATGTAAAAGAACAAGCCTTTACTACAATAGATAAAAAA
TTAAAGGAATTAACAATCTTAAAGGAATCACCTTACTTTGGAAGAGTTACTTTTAATGATTTAGAGTTTGATCAAAAGGA
TACTTTATATGTTGGTAGATTTGGAGTAACTCCAGAGGGAAGCTATGAGCCTGTAATAGTAGATTGGAGAGCCCCTGTGG
CTTCACTTTTTTATCATGGTAGTTTAGGAGAAGCAAGTTATACATCACCAGATGGACCTATAAAATGTGATATAGAAGGT
AGAAGACAGATTATAGTTAAAAAAGGAGAATTAAAGGGAGTTTTTGATTCAGCCATAGATGTAAAAGATGATATTTTACA
AATGGTTCTAAGTAATAATAGTTCTGATAAGCTTAAAGATGTAATAATGACAATTCAACAAGAGCAAGATGAAATCATAA
GAAAAGAGAGGACTTCTAATATAGTTGTAAATGGAGTAGCAGGTAGTGGTAAAACTACAATAGCACTTCATAGAGTTGCA
TACCTTTTATATAACTATAGAAAAGAATTAGAAGATAAAGTTATTATCTTAGGTCCAAATGGTATATTTATGGAGTATAT
TTCACAAGTATTACCTAGTCTTGGGGAAGTGGGAGTAAAACAGGAGACTTTTGCTAGTTTTGCTTTAAAAGAAATGGATA
GTGAATTATACATAATGAGTTTTGATAAGTATTTAGAAAAAATACTTTCAGAGGATATAGAGTTTATAGAGGATGCTAAA
TATAAAAATTCATATGAGATAATTGAAGATTTAGATAACCTAGTAAAAGAAATGGATAAGGATTATTTCCATGTTGAAGA
TGTAAAATACTTTGGTGATTTAGTTATTTCAAAAGAAGAAATAGAAGAAATGTTTAATAAACATTATGAGTATATGCCTT
TATTCAGAAGAAGTGAAAAAATTAAAAGAATAATATTATCTAAGATTAAGGATAAGAGAGACGAGAAAGTTTGGGAGCTT
AATGAAGAATTAAGAAAAGAAAAGGAAAAATTAACTCCTGAAGAACTTTTAATTGAAGAAAATAACTTAGAATTTAGAAG
AAAATTAAGAATAAGAGAAATTGTTAAGGAAGTAATGGATTCAAGAGCTAAGTTAGATAGATGGATTTCAAGAGAAGATG
TTTTAGATATCTATGATAGATTCAATGGAAATAAAAAAGAATATACAATAAATGATTTAGCACCAATATTATACTTAGCA
ATAAAATTAGAAGGTAAAAAAGCAACAAAAGATTATAGACATGTGGTTATAGATGAAGCTCAAGATTATTCACCACTTCA
ATTTAAAGTTGTAAGAGAATTAACAGGAACTAAGTATTTTACTGTTGTGGGAGACGTAAATCAAAGACTTATTAAATATT
CAGACTTAGCTCCTATGATGGAACTAGGAAAAATATTTGATGATGTAAATCCAGAGATTTATAACTTAAATAAAAGTTAT
AGAAGTACTTATGAAATAATGGAATATGCAAATAAATATCTTGATGAAGATAGAATAATTCCTATAGTTAGACATGGTAA
ACCAGTTGAGGAAATTGAATTCCATAATGATGAAGAACTTTCAGAAAGCATTATTGAGTCTTTAAAAGAATTTTCAAATG
AAGGCTTAGAAAGTATTGCTATTATAACAAGAGATAAAGAAGAGTTAGAAAAGGTGTATAATCTTATAAGCAATAAAGTG
CATTTAGTTAAGTTTGATAACGAAGATGTATTATATAAAGGTGGAAATGTTATAATACCATCTTACTTTGCAAAGGGATT
AGAATTTGATGGGGTTATTATTGTAGATAATGGATCATCAAAAGATGAAAATGAAGATCTAATAAAATATATAATGAGTA
CTAGAGCACTTCATAGATTAAAAGAAATACAATTTAAATAA

Upstream 100 bases:

>100_bases
TCATGCACTTTTTGACTTTTCATTTGTATTTTTAATGAGAGGAAAGTTAATGTTATAATTGGGTATAATGTAATAGAGAA
AGTAAGAAAGGAAGATTCTA

Downstream 100 bases:

>100_bases
TTTTACTTTTTAAAAGGATTTTATAAAAATAGATTTTAATGAAAGTTACAAGCATATTTTGAGAATTTCTAAACTAGATA
TTTTCATTATACTCCCTGTA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 706; Mature: 705

Protein sequence:

>706_residues
MTDKKDIEFLVEEKKLEEVSNILNEEMLSYINKRKFVTQYILDYRKNAVEEYKDDEDKLIEYFDHERYVKEQAFTTIDKK
LKELTILKESPYFGRVTFNDLEFDQKDTLYVGRFGVTPEGSYEPVIVDWRAPVASLFYHGSLGEASYTSPDGPIKCDIEG
RRQIIVKKGELKGVFDSAIDVKDDILQMVLSNNSSDKLKDVIMTIQQEQDEIIRKERTSNIVVNGVAGSGKTTIALHRVA
YLLYNYRKELEDKVIILGPNGIFMEYISQVLPSLGEVGVKQETFASFALKEMDSELYIMSFDKYLEKILSEDIEFIEDAK
YKNSYEIIEDLDNLVKEMDKDYFHVEDVKYFGDLVISKEEIEEMFNKHYEYMPLFRRSEKIKRIILSKIKDKRDEKVWEL
NEELRKEKEKLTPEELLIEENNLEFRRKLRIREIVKEVMDSRAKLDRWISREDVLDIYDRFNGNKKEYTINDLAPILYLA
IKLEGKKATKDYRHVVIDEAQDYSPLQFKVVRELTGTKYFTVVGDVNQRLIKYSDLAPMMELGKIFDDVNPEIYNLNKSY
RSTYEIMEYANKYLDEDRIIPIVRHGKPVEEIEFHNDEELSESIIESLKEFSNEGLESIAIITRDKEELEKVYNLISNKV
HLVKFDNEDVLYKGGNVIIPSYFAKGLEFDGVIIVDNGSSKDENEDLIKYIMSTRALHRLKEIQFK

Sequences:

>Translated_706_residues
MTDKKDIEFLVEEKKLEEVSNILNEEMLSYINKRKFVTQYILDYRKNAVEEYKDDEDKLIEYFDHERYVKEQAFTTIDKK
LKELTILKESPYFGRVTFNDLEFDQKDTLYVGRFGVTPEGSYEPVIVDWRAPVASLFYHGSLGEASYTSPDGPIKCDIEG
RRQIIVKKGELKGVFDSAIDVKDDILQMVLSNNSSDKLKDVIMTIQQEQDEIIRKERTSNIVVNGVAGSGKTTIALHRVA
YLLYNYRKELEDKVIILGPNGIFMEYISQVLPSLGEVGVKQETFASFALKEMDSELYIMSFDKYLEKILSEDIEFIEDAK
YKNSYEIIEDLDNLVKEMDKDYFHVEDVKYFGDLVISKEEIEEMFNKHYEYMPLFRRSEKIKRIILSKIKDKRDEKVWEL
NEELRKEKEKLTPEELLIEENNLEFRRKLRIREIVKEVMDSRAKLDRWISREDVLDIYDRFNGNKKEYTINDLAPILYLA
IKLEGKKATKDYRHVVIDEAQDYSPLQFKVVRELTGTKYFTVVGDVNQRLIKYSDLAPMMELGKIFDDVNPEIYNLNKSY
RSTYEIMEYANKYLDEDRIIPIVRHGKPVEEIEFHNDEELSESIIESLKEFSNEGLESIAIITRDKEELEKVYNLISNKV
HLVKFDNEDVLYKGGNVIIPSYFAKGLEFDGVIIVDNGSSKDENEDLIKYIMSTRALHRLKEIQFK
>Mature_705_residues
TDKKDIEFLVEEKKLEEVSNILNEEMLSYINKRKFVTQYILDYRKNAVEEYKDDEDKLIEYFDHERYVKEQAFTTIDKKL
KELTILKESPYFGRVTFNDLEFDQKDTLYVGRFGVTPEGSYEPVIVDWRAPVASLFYHGSLGEASYTSPDGPIKCDIEGR
RQIIVKKGELKGVFDSAIDVKDDILQMVLSNNSSDKLKDVIMTIQQEQDEIIRKERTSNIVVNGVAGSGKTTIALHRVAY
LLYNYRKELEDKVIILGPNGIFMEYISQVLPSLGEVGVKQETFASFALKEMDSELYIMSFDKYLEKILSEDIEFIEDAKY
KNSYEIIEDLDNLVKEMDKDYFHVEDVKYFGDLVISKEEIEEMFNKHYEYMPLFRRSEKIKRIILSKIKDKRDEKVWELN
EELRKEKEKLTPEELLIEENNLEFRRKLRIREIVKEVMDSRAKLDRWISREDVLDIYDRFNGNKKEYTINDLAPILYLAI
KLEGKKATKDYRHVVIDEAQDYSPLQFKVVRELTGTKYFTVVGDVNQRLIKYSDLAPMMELGKIFDDVNPEIYNLNKSYR
STYEIMEYANKYLDEDRIIPIVRHGKPVEEIEFHNDEELSESIIESLKEFSNEGLESIAIITRDKEELEKVYNLISNKVH
LVKFDNEDVLYKGGNVIIPSYFAKGLEFDGVIIVDNGSSKDENEDLIKYIMSTRALHRLKEIQFK

Specific function: Catalyzes the unwinding of duplex DNA in the 3' to 5' direction; this reaction is dependent on the hydrolysis of ATP [H]

COG id: COG3973

COG function: function code R; Superfamily I DNA and RNA helicases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 uvrD-like helicase ATP-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000212
- InterPro:   IPR014016 [H]

Pfam domain/function: PF00580 UvrD-helicase [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 82993; Mature: 82861

Theoretical pI: Translated: 4.68; Mature: 4.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDKKDIEFLVEEKKLEEVSNILNEEMLSYINKRKFVTQYILDYRKNAVEEYKDDEDKLI
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
EYFDHERYVKEQAFTTIDKKLKELTILKESPYFGRVTFNDLEFDQKDTLYVGRFGVTPEG
HHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCEEEECCCCCCCCCCEEEEEECCCCCC
SYEPVIVDWRAPVASLFYHGSLGEASYTSPDGPIKCDIEGRRQIIVKKGELKGVFDSAID
CCCCEEEECCCCHHHHHHCCCCCCCCCCCCCCCEEEEECCCEEEEEECCCCCHHHHHHCC
VKDDILQMVLSNNSSDKLKDVIMTIQQEQDEIIRKERTSNIVVNGVAGSGKTTIALHRVA
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHH
YLLYNYRKELEDKVIILGPNGIFMEYISQVLPSLGEVGVKQETFASFALKEMDSELYIMS
HHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCEEEEE
FDKYLEKILSEDIEFIEDAKYKNSYEIIEDLDNLVKEMDKDYFHVEDVKYFGDLVISKEE
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHCCHHH
IEEMFNKHYEYMPLFRRSEKIKRIILSKIKDKRDEKVWELNEELRKEKEKLTPEELLIEE
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHEEEC
NNLEFRRKLRIREIVKEVMDSRAKLDRWISREDVLDIYDRFNGNKKEYTINDLAPILYLA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHCCCCCCEEEHHHHHHHHHEE
IKLEGKKATKDYRHVVIDEAQDYSPLQFKVVRELTGTKYFTVVGDVNQRLIKYSDLAPMM
EEECCCCCCCHHHHEEECCCCCCCCHHHHHHHHHHCCEEEEEEECHHHHHHHHHHHHHHH
ELGKIFDDVNPEIYNLNKSYRSTYEIMEYANKYLDEDRIIPIVRHGKPVEEIEFHNDEEL
HHHHHHHCCCCCEEECCHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHCCCCHHHH
SESIIESLKEFSNEGLESIAIITRDKEELEKVYNLISNKVHLVKFDNEDVLYKGGNVIIP
HHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHCCCEEEEEECCCCEEEECCCEEEC
SYFAKGLEFDGVIIVDNGSSKDENEDLIKYIMSTRALHRLKEIQFK
HHHHCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TDKKDIEFLVEEKKLEEVSNILNEEMLSYINKRKFVTQYILDYRKNAVEEYKDDEDKLI
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
EYFDHERYVKEQAFTTIDKKLKELTILKESPYFGRVTFNDLEFDQKDTLYVGRFGVTPEG
HHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCEEEECCCCCCCCCCEEEEEECCCCCC
SYEPVIVDWRAPVASLFYHGSLGEASYTSPDGPIKCDIEGRRQIIVKKGELKGVFDSAID
CCCCEEEECCCCHHHHHHCCCCCCCCCCCCCCCEEEEECCCEEEEEECCCCCHHHHHHCC
VKDDILQMVLSNNSSDKLKDVIMTIQQEQDEIIRKERTSNIVVNGVAGSGKTTIALHRVA
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHH
YLLYNYRKELEDKVIILGPNGIFMEYISQVLPSLGEVGVKQETFASFALKEMDSELYIMS
HHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCEEEEE
FDKYLEKILSEDIEFIEDAKYKNSYEIIEDLDNLVKEMDKDYFHVEDVKYFGDLVISKEE
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHCCHHH
IEEMFNKHYEYMPLFRRSEKIKRIILSKIKDKRDEKVWELNEELRKEKEKLTPEELLIEE
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHEEEC
NNLEFRRKLRIREIVKEVMDSRAKLDRWISREDVLDIYDRFNGNKKEYTINDLAPILYLA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHCCCCCCEEEHHHHHHHHHEE
IKLEGKKATKDYRHVVIDEAQDYSPLQFKVVRELTGTKYFTVVGDVNQRLIKYSDLAPMM
EEECCCCCCCHHHHEEECCCCCCCCHHHHHHHHHHCCEEEEEEECHHHHHHHHHHHHHHH
ELGKIFDDVNPEIYNLNKSYRSTYEIMEYANKYLDEDRIIPIVRHGKPVEEIEFHNDEEL
HHHHHHHCCCCCEEECCHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHCCCCHHHH
SESIIESLKEFSNEGLESIAIITRDKEELEKVYNLISNKVHLVKFDNEDVLYKGGNVIIP
HHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHCCCEEEEEECCCCEEEECCCEEEC
SYFAKGLEFDGVIIVDNGSSKDENEDLIKYIMSTRALHRLKEIQFK
HHHHCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]