Click here to switch to the map view.

The map label for this gene is aroC [H]

Identifier: 161485643

GI number: 161485643

Start: 872716

End: 873789

Strand: Direct

Name: aroC [H]

Synonym: CPE0697

Alternate gene names: 161485643

Gene position: 872716-873789 (Clockwise)

Preceding gene: 18309678

Following gene: 18309680

Centisome position: 28.79

GC content: 32.31

Gene sequence:

>1074_bases
ATGGGAGGAGTTTGGGGTAATAAAATAAAATTATCTATATTTGGAGAATCTCATGGAGAAGGAATAGGAATAGTAATAGA
TGGAATAGAACCTGGAATCAAAGTAAATATGGATAACATAGAAAAAGATATGGAAAGAAGAGCACCAGGAAGAAATAGTT
TATCAACTCAGAGAAAAGAAGGGGATAAACCAGAAATTTTAAGTGGAATATTTAATGGAATCACCACAGGGGCTCCTATT
TCAATGATAATAAGAAATACAGATAAAAGATCTAGGGATTATTCAAAAATAAAAGATGTAATGAGACCAGGTCATGCGGA
TTTCCCAGGGTATGTAAGATATAATGGCTTTAATGATTATAGAGGGGGAGGACATTTCTCAGGAAGAATAACAGCTCCAT
TAGTTTTTGCTGGAGCCTTAGCTAAGGAAATACTTAAGGAAAAAGGTATAACTATTGGTTCTCATATTAAGCAAGTTGGA
AAAGTTAAGGATTCTTCCTTTGATGCATTAAATTTAAAGAAAGAAGGTTTAGAAGAACTTTTAACTAAAGAACTTCCAGT
AATAGATACAAATAAAATAGAAGAAATTAAGGAAGAGATTACTTCATATAGAATGGAAGGAGATTCTATTGGAGGAATTG
TTGAGTGTGCCATAGTAGGACTAGAGGCTGGTATAGGAAATCCATTCTTTGATTCTTTAGAAAGTACCATAGCTCATTTA
GCTTTTTCAGTACCAGCTGTAAAGGGAATTGAATTTGGAGCAGGTTTTGACTTTGTAAATATGAAAGGCTCAGAAGCAAA
TGACGAATATTTCATAGAAGATGAAAAAGTTAAGACATACTCTAATAATAATGGAGGAATAACTGGTGGAATATCAAATG
GAATGCCAGTTATATTCAGAGTTGTTATAAAACCTACACCATCTATTTCTAAAGAACAAAGAACTATAAATATAAAAAAT
ATGACAGAGGAAGTTCTAAGTGTAAATGGGAGACACGATCCTTGTATAGTTCAAAGAGCCTTAGTTGTTATAGAAGCCAT
TGCAGCTATTTCTATATTAGAGTTAATAAAATAA

Upstream 100 bases:

>100_bases
TTTTAAGAGCTTAGGTGGAATTTTAAGAGAAGAATAATATATAGAATATTCAACAGAAGGGAGGAAGCTTTTAGAGATAA
TAAGCTTTAAAAGCAAATAA

Downstream 100 bases:

>100_bases
AAAGTTTAAAGTATAGTAGACTTTTATGATAATAGGATATTAATTAAAATTAATCTTTGTCTACTATATTTAAAAATATT
TCAAAGTGATTCACTTTATC

Product: chorismate synthase

Products: NA

Alternate protein names: 5-enolpyruvylshikimate-3-phosphate phospholyase [H]

Number of amino acids: Translated: 357; Mature: 356

Protein sequence:

>357_residues
MGGVWGNKIKLSIFGESHGEGIGIVIDGIEPGIKVNMDNIEKDMERRAPGRNSLSTQRKEGDKPEILSGIFNGITTGAPI
SMIIRNTDKRSRDYSKIKDVMRPGHADFPGYVRYNGFNDYRGGGHFSGRITAPLVFAGALAKEILKEKGITIGSHIKQVG
KVKDSSFDALNLKKEGLEELLTKELPVIDTNKIEEIKEEITSYRMEGDSIGGIVECAIVGLEAGIGNPFFDSLESTIAHL
AFSVPAVKGIEFGAGFDFVNMKGSEANDEYFIEDEKVKTYSNNNGGITGGISNGMPVIFRVVIKPTPSISKEQRTINIKN
MTEEVLSVNGRHDPCIVQRALVVIEAIAAISILELIK

Sequences:

>Translated_357_residues
MGGVWGNKIKLSIFGESHGEGIGIVIDGIEPGIKVNMDNIEKDMERRAPGRNSLSTQRKEGDKPEILSGIFNGITTGAPI
SMIIRNTDKRSRDYSKIKDVMRPGHADFPGYVRYNGFNDYRGGGHFSGRITAPLVFAGALAKEILKEKGITIGSHIKQVG
KVKDSSFDALNLKKEGLEELLTKELPVIDTNKIEEIKEEITSYRMEGDSIGGIVECAIVGLEAGIGNPFFDSLESTIAHL
AFSVPAVKGIEFGAGFDFVNMKGSEANDEYFIEDEKVKTYSNNNGGITGGISNGMPVIFRVVIKPTPSISKEQRTINIKN
MTEEVLSVNGRHDPCIVQRALVVIEAIAAISILELIK
>Mature_356_residues
GGVWGNKIKLSIFGESHGEGIGIVIDGIEPGIKVNMDNIEKDMERRAPGRNSLSTQRKEGDKPEILSGIFNGITTGAPIS
MIIRNTDKRSRDYSKIKDVMRPGHADFPGYVRYNGFNDYRGGGHFSGRITAPLVFAGALAKEILKEKGITIGSHIKQVGK
VKDSSFDALNLKKEGLEELLTKELPVIDTNKIEEIKEEITSYRMEGDSIGGIVECAIVGLEAGIGNPFFDSLESTIAHLA
FSVPAVKGIEFGAGFDFVNMKGSEANDEYFIEDEKVKTYSNNNGGITGGISNGMPVIFRVVIKPTPSISKEQRTINIKNM
TEEVLSVNGRHDPCIVQRALVVIEAIAAISILELIK

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; seventh step. [C]

COG id: COG0082

COG function: function code E; Chorismate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the chorismate synthase family [H]

Homologues:

Organism=Escherichia coli, GI1788669, Length=355, Percent_Identity=43.943661971831, Blast_Score=253, Evalue=2e-68,
Organism=Saccharomyces cerevisiae, GI6321290, Length=364, Percent_Identity=37.0879120879121, Blast_Score=244, Evalue=1e-65,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000453
- InterPro:   IPR020541 [H]

Pfam domain/function: PF01264 Chorismate_synt [H]

EC number: =4.2.3.5 [H]

Molecular weight: Translated: 38843; Mature: 38712

Theoretical pI: Translated: 6.02; Mature: 6.02

Prosite motif: PS00788 CHORISMATE_SYNTHASE_2 ; PS00789 CHORISMATE_SYNTHASE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGGVWGNKIKLSIFGESHGEGIGIVIDGIEPGIKVNMDNIEKDMERRAPGRNSLSTQRKE
CCCCCCCEEEEEEECCCCCCEEEEEEECCCCCCEECHHHHHHHHHHCCCCCCCCCHHHHC
GDKPEILSGIFNGITTGAPISMIIRNTDKRSRDYSKIKDVMRPGHADFPGYVRYNGFNDY
CCCHHHHHHHHHHHCCCCCCEEEEECCCCCCHHHHHHHHHHCCCCCCCCCEEEECCCCCC
RGGGHFSGRITAPLVFAGALAKEILKEKGITIGSHIKQVGKVKDSSFDALNLKKEGLEEL
CCCCCCCCEEHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHH
LTKELPVIDTNKIEEIKEEITSYRMEGDSIGGIVECAIVGLEAGIGNPFFDSLESTIAHL
HHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
AFSVPAVKGIEFGAGFDFVNMKGSEANDEYFIEDEKVKTYSNNNGGITGGISNGMPVIFR
HHHCCCCCCCCCCCCCCEEECCCCCCCCCEEEECCCEEEEECCCCCEECCCCCCCCEEEE
VVIKPTPSISKEQRTINIKNMTEEVLSVNGRHDPCIVQRALVVIEAIAAISILELIK
EEECCCCCCCCCHHEEEHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure 
GGVWGNKIKLSIFGESHGEGIGIVIDGIEPGIKVNMDNIEKDMERRAPGRNSLSTQRKE
CCCCCCEEEEEEECCCCCCEEEEEEECCCCCCEECHHHHHHHHHHCCCCCCCCCHHHHC
GDKPEILSGIFNGITTGAPISMIIRNTDKRSRDYSKIKDVMRPGHADFPGYVRYNGFNDY
CCCHHHHHHHHHHHCCCCCCEEEEECCCCCCHHHHHHHHHHCCCCCCCCCEEEECCCCCC
RGGGHFSGRITAPLVFAGALAKEILKEKGITIGSHIKQVGKVKDSSFDALNLKKEGLEEL
CCCCCCCCEEHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHH
LTKELPVIDTNKIEEIKEEITSYRMEGDSIGGIVECAIVGLEAGIGNPFFDSLESTIAHL
HHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
AFSVPAVKGIEFGAGFDFVNMKGSEANDEYFIEDEKVKTYSNNNGGITGGISNGMPVIFR
HHHCCCCCCCCCCCCCCEEECCCCCCCCCEEEECCCEEEEECCCCCEECCCCCCCCEEEE
VVIKPTPSISKEQRTINIKNMTEEVLSVNGRHDPCIVQRALVVIEAIAAISILELIK
EEECCCCCCCCCHHEEEHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12622808 [H]