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The map label for this gene is ribAB [H]

Identifier: 229259638

GI number: 229259638

Start: 760616

End: 761746

Strand: Reverse

Name: ribAB [H]

Synonym: RSc0713

Alternate gene names: 229259638

Gene position: 761746-760616 (Counterclockwise)

Preceding gene: 17545433

Following gene: 17545431

Centisome position: 20.5

GC content: 68.08

Gene sequence:

>1131_bases
ATGTCCATCGCCACAGTCGAAGAAATCATTGCCGAAATCCGCGCCGGCCGGATGGTCATCCTGGTCGATGAGGAAGACCG
CGAAAACGAAGGTGACCTGATCCTGGCAGCCGATTTCGTCACGCCCGAGGCCATCAACTTCATGGCCAGGTTCGGCCGTG
GCCTGATCTGCCTGACGCTGACCGCCGAGCGCTGCCGCCAGCTCGACCTGCCGCTGATGGTCACCCGCAACGGCACGCCG
CATGGCACCAATTTCACCGTTTCCATCGAGGCCGCCGAGGGCGTCACCACCGGCATCTCGGCCGCCGACCGTGCGCGCAC
CGTGCAAGTCGCCGTGGCCCGCAGTGCCAGCCCCGACGATCTGGTCCAGCCCGGCCACATCTTCCCGCTGATGGCGCAGC
CCGGCGGCGTGCTGATGCGCGCAGGCCATACCGAAGCCGGCTGCGACCTGGCCTCGCTGGCCGGCCTGACGCCCGCCTCG
GTCATCTGCGAGATCATGAAGGACGATGGCACCATGGCCCGCCTGCCGGACCTGGTGGAATTCGCCCGCGAGCACGGCCT
GAAGATCGGCACCATCGCCGACCTGATCCAATACCGCAGCCGCACCGAGAGCATCGTCGAGCGCATCGGCGAGCGCAACA
TGGAAACCCAGTTCGGCACCTTCCGCGCCGTGGCCTTCCGTGACCATGCCGCCGGCCGCGCGCACCTGGCGCTGGTCAAG
GGCACGCCGACGCCCGCCACCGAGACGCTGGTGCGCGTGCACGAGCCGCTGTCGGTGCTGGACCTGCTGGAATGTCAGCG
CACCACACACTCGTGGAGCGTGCCCGCCGCCCTGCGCGCGGTGCAAGCGGCACCGACCGGCGTGGTCGTGCTGCTCAACT
GCGGCGACTCGCCCGAGCGGCTGTTCACCCAGTTCAGCGCCCTGGATGCTCCGCAGGAACGTCCGCGCAGCAAGCCCGAT
CCGCGCATCTACGGCATCGGCGCGCAGATCCTCAAGGACGTGGGCGTGGGCAAGATGCGTGTGCTTGCCTCACCGCTCAA
GCTGCCGAGCATGGCCGGCTATGACCTGGAGGTCACGGCCTACCAGTCGATGGCCGATACGCCGCAGGCAACAACGGCCG
CCACGCATTGA

Upstream 100 bases:

>100_bases
CCCGGCCCCCGGGCCGCCTTCGCGTACAATAATGGGTTCCCATTTTTGCCGTCGCGCGGCCGCCAACGCGCTGGCCGGCG
GCCCGCTCCAGTTACCCGCC

Downstream 100 bases:

>100_bases
GGTTCCGGCGGTGGCCGCGCGCCGCCGCTGCTGTCTTTCTTCTTCCCTGACGTTGCCCTGACGGCGACACCAACCGGACT
ACACCATGGATCACGGCTTC

Product: bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II-like protein

Products: NA

Alternate protein names: DHBP synthase [H]

Number of amino acids: Translated: 376; Mature: 375

Protein sequence:

>376_residues
MSIATVEEIIAEIRAGRMVILVDEEDRENEGDLILAADFVTPEAINFMARFGRGLICLTLTAERCRQLDLPLMVTRNGTP
HGTNFTVSIEAAEGVTTGISAADRARTVQVAVARSASPDDLVQPGHIFPLMAQPGGVLMRAGHTEAGCDLASLAGLTPAS
VICEIMKDDGTMARLPDLVEFAREHGLKIGTIADLIQYRSRTESIVERIGERNMETQFGTFRAVAFRDHAAGRAHLALVK
GTPTPATETLVRVHEPLSVLDLLECQRTTHSWSVPAALRAVQAAPTGVVVLLNCGDSPERLFTQFSALDAPQERPRSKPD
PRIYGIGAQILKDVGVGKMRVLASPLKLPSMAGYDLEVTAYQSMADTPQATTAATH

Sequences:

>Translated_376_residues
MSIATVEEIIAEIRAGRMVILVDEEDRENEGDLILAADFVTPEAINFMARFGRGLICLTLTAERCRQLDLPLMVTRNGTP
HGTNFTVSIEAAEGVTTGISAADRARTVQVAVARSASPDDLVQPGHIFPLMAQPGGVLMRAGHTEAGCDLASLAGLTPAS
VICEIMKDDGTMARLPDLVEFAREHGLKIGTIADLIQYRSRTESIVERIGERNMETQFGTFRAVAFRDHAAGRAHLALVK
GTPTPATETLVRVHEPLSVLDLLECQRTTHSWSVPAALRAVQAAPTGVVVLLNCGDSPERLFTQFSALDAPQERPRSKPD
PRIYGIGAQILKDVGVGKMRVLASPLKLPSMAGYDLEVTAYQSMADTPQATTAATH
>Mature_375_residues
SIATVEEIIAEIRAGRMVILVDEEDRENEGDLILAADFVTPEAINFMARFGRGLICLTLTAERCRQLDLPLMVTRNGTPH
GTNFTVSIEAAEGVTTGISAADRARTVQVAVARSASPDDLVQPGHIFPLMAQPGGVLMRAGHTEAGCDLASLAGLTPASV
ICEIMKDDGTMARLPDLVEFAREHGLKIGTIADLIQYRSRTESIVERIGERNMETQFGTFRAVAFRDHAAGRAHLALVKG
TPTPATETLVRVHEPLSVLDLLECQRTTHSWSVPAALRAVQAAPTGVVVLLNCGDSPERLFTQFSALDAPQERPRSKPDP
RIYGIGAQILKDVGVGKMRVLASPLKLPSMAGYDLEVTAYQSMADTPQATTAATH

Specific function: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate [H]

COG id: COG0108

COG function: function code H; 3,4-dihydroxy-2-butanone 4-phosphate synthase

Gene ontology:

Cell location: Membrane-Associated [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the GTP cyclohydrolase II family [H]

Homologues:

Organism=Escherichia coli, GI1789420, Length=198, Percent_Identity=55.5555555555556, Blast_Score=230, Evalue=1e-61,
Organism=Saccharomyces cerevisiae, GI6320695, Length=204, Percent_Identity=42.156862745098, Blast_Score=169, Evalue=6e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017945
- InterPro:   IPR000422
- InterPro:   IPR000926
- InterPro:   IPR016299 [H]

Pfam domain/function: PF00926 DHBP_synthase; PF00925 GTP_cyclohydro2 [H]

EC number: =4.1.99.12 [H]

Molecular weight: Translated: 40427; Mature: 40296

Theoretical pI: Translated: 5.43; Mature: 5.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIATVEEIIAEIRAGRMVILVDEEDRENEGDLILAADFVTPEAINFMARFGRGLICLTL
CCCHHHHHHHHHHHCCCEEEEECCCCCCCCCCEEEEECCCCHHHHHHHHHHCCCEEEEEE
TAERCRQLDLPLMVTRNGTPHGTNFTVSIEAAEGVTTGISAADRARTVQVAVARSASPDD
EHHHHHHCCCCEEEECCCCCCCCEEEEEEECCCCCCCCCCHHHHCEEEEEEEECCCCCHH
LVQPGHIFPLMAQPGGVLMRAGHTEAGCDLASLAGLTPASVICEIMKDDGTMARLPDLVE
CCCCCCEEEEEECCCCEEEECCCCCCCCCHHHHCCCCHHHHHHHHHHCCCCHHHHHHHHH
FAREHGLKIGTIADLIQYRSRTESIVERIGERNMETQFGTFRAVAFRDHAAGRAHLALVK
HHHHCCCEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEECCCCCCEEEEEEE
GTPTPATETLVRVHEPLSVLDLLECQRTTHSWSVPAALRAVQAAPTGVVVLLNCGDSPER
CCCCCHHHHHHHHHCCHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCEEEEEECCCCHHH
LFTQFSALDAPQERPRSKPDPRIYGIGAQILKDVGVGKMRVLASPLKLPSMAGYDLEVTA
HHHHHHHCCCCHHCCCCCCCCEEEECHHHHHHHCCCCHHHHHHCCCCCCCCCCCCEEEEE
YQSMADTPQATTAATH
HHHHCCCCCCCCCCCC
>Mature Secondary Structure 
SIATVEEIIAEIRAGRMVILVDEEDRENEGDLILAADFVTPEAINFMARFGRGLICLTL
CCHHHHHHHHHHHCCCEEEEECCCCCCCCCCEEEEECCCCHHHHHHHHHHCCCEEEEEE
TAERCRQLDLPLMVTRNGTPHGTNFTVSIEAAEGVTTGISAADRARTVQVAVARSASPDD
EHHHHHHCCCCEEEECCCCCCCCEEEEEEECCCCCCCCCCHHHHCEEEEEEEECCCCCHH
LVQPGHIFPLMAQPGGVLMRAGHTEAGCDLASLAGLTPASVICEIMKDDGTMARLPDLVE
CCCCCCEEEEEECCCCEEEECCCCCCCCCHHHHCCCCHHHHHHHHHHCCCCHHHHHHHHH
FAREHGLKIGTIADLIQYRSRTESIVERIGERNMETQFGTFRAVAFRDHAAGRAHLALVK
HHHHCCCEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEECCCCCCEEEEEEE
GTPTPATETLVRVHEPLSVLDLLECQRTTHSWSVPAALRAVQAAPTGVVVLLNCGDSPER
CCCCCHHHHHHHHHCCHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCEEEEEECCCCHHH
LFTQFSALDAPQERPRSKPDPRIYGIGAQILKDVGVGKMRVLASPLKLPSMAGYDLEVTA
HHHHHHHCCCCHHCCCCCCCCEEEECHHHHHHHCCCCHHHHHHCCCCCCCCCCCCEEEEE
YQSMADTPQATTAATH
HHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10761919 [H]