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The map label for this gene is tcp [H]

Identifier: 17547855

GI number: 17547855

Start: 3382588

End: 3384573

Strand: Reverse

Name: tcp [H]

Synonym: RSc3136

Alternate gene names: 17547855

Gene position: 3384573-3382588 (Counterclockwise)

Preceding gene: 17547856

Following gene: 17547847

Centisome position: 91.07

GC content: 71.25

Gene sequence:

>1986_bases
ATGCGAACGTCCGCCCCTCAGCACGCCCCCCAATCCGCGACCAGCCTGGGCTCCCGGCTGGCCGTCGCCGGCCTGGCCGC
CCTGGTCCTGGTGTTCGGCGCCTTTGCGCTGGCGATCTCGCAATCCAGCCTGCGCACGCTGGAAGACCATGCGCAGTCGG
CCATGCGCGACCAGGAAGCCGCCATGCGCGACATGATCGCCCTGTTCGACGGCACCATGCGCACCGAGGCCGACCGCTTC
CTGACCGCCTTCGCGGATGCGGCGCCCGGCCCGTACAGCGTGGACCCGGCGCAGACCGTGGCGGTGGCCGGCAAGCCCAC
GCCCACCTTCAGGAGCGGCGACACGGCGATGAACCTCGATTTCGCCATCCCCGACAAGTTCTTCGCCCGCACCGGCGGCA
CCATCGCCACCGTGTTCGCCCGCACCGGCGACGATTTCGTGCGCGTGACCACCTCGCTCAAGAAAGAGAACGGCGAGCGC
GCCATCGGCACGCTGCTCGACCGCGCCCATCCGAGCTACAGGGCGCTGATGGCGGGCGAGTCGTTCCGCGGGCTGGCATG
GCTGTTCGGCGTGCCCTACATGAGCAAGTACGAGCCGGTGCGCGATGCCGCGGGCAAGGTGGTCGGCGCCCTGTACGTGG
GCGTGGACGTGCGCGCGGAACTGGCGCTGCTCAAGGACAAGATCCGCTCGCACGGCATCGGCAAGACCGGCGGCTACTTC
GTCATCGACGGCAAGGCGGGCGCCGACCAGGGCAAGGTGCTGATCGACCGCGACCCGGGCCGCGAAGGCAAGAACCTGCT
GGATGCCAAGGACGCCGACGGCCTGGCCTGGGTGCGCGAGATGATCGAGCGCAGGGACGGCATCCTGCGCCACACGCTGG
CCGACACCGAAGGCGGCCCGGCGCGCGCGCGCTTCACCGTGTTCACGCAGTATCCGGACTGGAAGCTGGTGATTGCCGGC
ACCGCCTACGTGGATGAGCTGGAGGCCGACCTGGTCTCGGCGCGCAACCGCTTCCTGCTGCTCGGCCTGGCGCTGGGCGC
GCTGCTGGCGGGCGGCCTGTACTGGATGCTGCGCCGCGCGGTCAGCGCGCCGCTGGCCGAGGTGGCGGGCGTGGCCCGGC
GCGTGGCCGCCGGCGACCTGACGCACCGCTTCTCCGGCACCCGCCGCGACGAGATCGGCCAACTGATGCACGCCATCAAC
GGCTTGGGCGACGGCCTGAGCGGCATTGTCGACAAGGTGCGCGCGAGCGCCTCGACCATCGCCTCGAGCACCGGCCAGAT
CGCCGCCGGCAACGTCGACCTGTCGGCGCGTACCGAGGCGCAGGCCGGCAACCTGGAGCGCACCGCCTCCAGCATCGAGC
AACTGGCCGCCACCGTGCGCCAGAACGCCGACAGCGCTCAGCATGCGCACGACATGGTGCAGTCCGCCAGCGAGGCCGCC
AACGCGGGCGGCCGGACGGTGGCGCGGCTGGTCGGCACCATGTCGGGCATCCACACGACGGCGCAGAAGATTGCCGACAT
CACCGGCATCATCGACGGCATCGCCTTCCAGACCAACATCCTGGCGCTGAACGCCGCCGTGGAGGCGGCCCGCGCGGGCG
AACAGGGTCGCGGCTTCGCGGTCGTGGCCGGCGAGGTGCGCAGCCTCGCGCAACGCAGCGCGGCGGCCGCCAAGGAAATC
AAGGAACTGATCAGCCGCTCGGTGCAGGAAGTGCAGGCCGGCAACGAAGCGGCGCGCGGCGCGGGCGAGGCCATGCAGGA
CATCGTCACGCGGGTCGAGCGCATCGCCGGCATCATGGGCGAGATCAGCCACGCCTCGCGCGAGCAGTCGCAGGGCATCG
AGGAGGTCAACCGCGCGGTGACCTCGATGGATGAGGTGACGCAGCAGAACGCCGCGCTGGTGGAAGAAGCCGCCGCCGCG
GCCGAGAGCCTGCGGCAGCAGGCCCAGGAACTGCGCGGCGCGGTGGATGTGTTCCGGCTGGCCTGA

Upstream 100 bases:

>100_bases
CGAAGATCAACAAAGTTTGAGGATTGCAAAACGTTTGCGCTCAAGCTTTTTTCCGATGATCCGTTTTTAGTGCAAACGAC
GATCATCCGAAAACGCCCCC

Downstream 100 bases:

>100_bases
GCCGCGCCGGCGCGCGGGCCGCTAGTGCAGCATCACGCGCCGCACCAGCGCCACCAGCGGCGGCCGGATCGAGCGCTCGA
TGCCCGGCTTGAGCCGCAGC

Product: methyl-accepting chemotaxis transmembrane protein

Products: NA

Alternate protein names: Citrate chemoreceptor protein [H]

Number of amino acids: Translated: 661; Mature: 661

Protein sequence:

>661_residues
MRTSAPQHAPQSATSLGSRLAVAGLAALVLVFGAFALAISQSSLRTLEDHAQSAMRDQEAAMRDMIALFDGTMRTEADRF
LTAFADAAPGPYSVDPAQTVAVAGKPTPTFRSGDTAMNLDFAIPDKFFARTGGTIATVFARTGDDFVRVTTSLKKENGER
AIGTLLDRAHPSYRALMAGESFRGLAWLFGVPYMSKYEPVRDAAGKVVGALYVGVDVRAELALLKDKIRSHGIGKTGGYF
VIDGKAGADQGKVLIDRDPGREGKNLLDAKDADGLAWVREMIERRDGILRHTLADTEGGPARARFTVFTQYPDWKLVIAG
TAYVDELEADLVSARNRFLLLGLALGALLAGGLYWMLRRAVSAPLAEVAGVARRVAAGDLTHRFSGTRRDEIGQLMHAIN
GLGDGLSGIVDKVRASASTIASSTGQIAAGNVDLSARTEAQAGNLERTASSIEQLAATVRQNADSAQHAHDMVQSASEAA
NAGGRTVARLVGTMSGIHTTAQKIADITGIIDGIAFQTNILALNAAVEAARAGEQGRGFAVVAGEVRSLAQRSAAAAKEI
KELISRSVQEVQAGNEAARGAGEAMQDIVTRVERIAGIMGEISHASREQSQGIEEVNRAVTSMDEVTQQNAALVEEAAAA
AESLRQQAQELRGAVDVFRLA

Sequences:

>Translated_661_residues
MRTSAPQHAPQSATSLGSRLAVAGLAALVLVFGAFALAISQSSLRTLEDHAQSAMRDQEAAMRDMIALFDGTMRTEADRF
LTAFADAAPGPYSVDPAQTVAVAGKPTPTFRSGDTAMNLDFAIPDKFFARTGGTIATVFARTGDDFVRVTTSLKKENGER
AIGTLLDRAHPSYRALMAGESFRGLAWLFGVPYMSKYEPVRDAAGKVVGALYVGVDVRAELALLKDKIRSHGIGKTGGYF
VIDGKAGADQGKVLIDRDPGREGKNLLDAKDADGLAWVREMIERRDGILRHTLADTEGGPARARFTVFTQYPDWKLVIAG
TAYVDELEADLVSARNRFLLLGLALGALLAGGLYWMLRRAVSAPLAEVAGVARRVAAGDLTHRFSGTRRDEIGQLMHAIN
GLGDGLSGIVDKVRASASTIASSTGQIAAGNVDLSARTEAQAGNLERTASSIEQLAATVRQNADSAQHAHDMVQSASEAA
NAGGRTVARLVGTMSGIHTTAQKIADITGIIDGIAFQTNILALNAAVEAARAGEQGRGFAVVAGEVRSLAQRSAAAAKEI
KELISRSVQEVQAGNEAARGAGEAMQDIVTRVERIAGIMGEISHASREQSQGIEEVNRAVTSMDEVTQQNAALVEEAAAA
AESLRQQAQELRGAVDVFRLA
>Mature_661_residues
MRTSAPQHAPQSATSLGSRLAVAGLAALVLVFGAFALAISQSSLRTLEDHAQSAMRDQEAAMRDMIALFDGTMRTEADRF
LTAFADAAPGPYSVDPAQTVAVAGKPTPTFRSGDTAMNLDFAIPDKFFARTGGTIATVFARTGDDFVRVTTSLKKENGER
AIGTLLDRAHPSYRALMAGESFRGLAWLFGVPYMSKYEPVRDAAGKVVGALYVGVDVRAELALLKDKIRSHGIGKTGGYF
VIDGKAGADQGKVLIDRDPGREGKNLLDAKDADGLAWVREMIERRDGILRHTLADTEGGPARARFTVFTQYPDWKLVIAG
TAYVDELEADLVSARNRFLLLGLALGALLAGGLYWMLRRAVSAPLAEVAGVARRVAAGDLTHRFSGTRRDEIGQLMHAIN
GLGDGLSGIVDKVRASASTIASSTGQIAAGNVDLSARTEAQAGNLERTASSIEQLAATVRQNADSAQHAHDMVQSASEAA
NAGGRTVARLVGTMSGIHTTAQKIADITGIIDGIAFQTNILALNAAVEAARAGEQGRGFAVVAGEVRSLAQRSAAAAKEI
KELISRSVQEVQAGNEAARGAGEAMQDIVTRVERIAGIMGEISHASREQSQGIEEVNRAVTSMDEVTQQNAALVEEAAAA
AESLRQQAQELRGAVDVFRLA

Specific function: Acts as a receptor for citrate and mediates taxis away from phenol. Also mediates an attractant response to metal-citrate complexes [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1787690, Length=336, Percent_Identity=51.4880952380952, Blast_Score=293, Evalue=2e-80,
Organism=Escherichia coli, GI1788194, Length=391, Percent_Identity=44.5012787723785, Blast_Score=285, Evalue=9e-78,
Organism=Escherichia coli, GI1788195, Length=308, Percent_Identity=54.5454545454545, Blast_Score=281, Evalue=8e-77,
Organism=Escherichia coli, GI2367378, Length=324, Percent_Identity=53.0864197530864, Blast_Score=268, Evalue=8e-73,
Organism=Escherichia coli, GI1789453, Length=318, Percent_Identity=40.251572327044, Blast_Score=223, Evalue=2e-59,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR003122
- InterPro:   IPR004091
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal; PF02203 TarH [H]

EC number: NA

Molecular weight: Translated: 69762; Mature: 69762

Theoretical pI: Translated: 6.46; Mature: 6.46

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRTSAPQHAPQSATSLGSRLAVAGLAALVLVFGAFALAISQSSLRTLEDHAQSAMRDQEA
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AMRDMIALFDGTMRTEADRFLTAFADAAPGPYSVDPAQTVAVAGKPTPTFRSGDTAMNLD
HHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCHHHEEEECCCCCCCCCCCCCEEEEE
FAIPDKFFARTGGTIATVFARTGDDFVRVTTSLKKENGERAIGTLLDRAHPSYRALMAGE
EECCHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHCCC
SFRGLAWLFGVPYMSKYEPVRDAAGKVVGALYVGVDVRAELALLKDKIRSHGIGKTGGYF
CCCCHHHHHCCCCHHHCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCEE
VIDGKAGADQGKVLIDRDPGREGKNLLDAKDADGLAWVREMIERRDGILRHTLADTEGGP
EEECCCCCCCCCEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHCCCCCCC
ARARFTVFTQYPDWKLVIAGTAYVDELEADLVSARNRFLLLGLALGALLAGGLYWMLRRA
CEEEEEEEEECCCEEEEEECHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
VSAPLAEVAGVARRVAAGDLTHRFSGTRRDEIGQLMHAINGLGDGLSGIVDKVRASASTI
HHCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
ASSTGQIAAGNVDLSARTEAQAGNLERTASSIEQLAATVRQNADSAQHAHDMVQSASEAA
HCCCCCEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
NAGGRTVARLVGTMSGIHTTAQKIADITGIIDGIAFQTNILALNAAVEAARAGEQGRGFA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEE
VVAGEVRSLAQRSAAAAKEIKELISRSVQEVQAGNEAARGAGEAMQDIVTRVERIAGIMG
EEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
EISHASREQSQGIEEVNRAVTSMDEVTQQNAALVEEAAAAAESLRQQAQELRGAVDVFRL
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
A
C
>Mature Secondary Structure
MRTSAPQHAPQSATSLGSRLAVAGLAALVLVFGAFALAISQSSLRTLEDHAQSAMRDQEA
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AMRDMIALFDGTMRTEADRFLTAFADAAPGPYSVDPAQTVAVAGKPTPTFRSGDTAMNLD
HHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCHHHEEEECCCCCCCCCCCCCEEEEE
FAIPDKFFARTGGTIATVFARTGDDFVRVTTSLKKENGERAIGTLLDRAHPSYRALMAGE
EECCHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHCCC
SFRGLAWLFGVPYMSKYEPVRDAAGKVVGALYVGVDVRAELALLKDKIRSHGIGKTGGYF
CCCCHHHHHCCCCHHHCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCEE
VIDGKAGADQGKVLIDRDPGREGKNLLDAKDADGLAWVREMIERRDGILRHTLADTEGGP
EEECCCCCCCCCEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHCCCCCCC
ARARFTVFTQYPDWKLVIAGTAYVDELEADLVSARNRFLLLGLALGALLAGGLYWMLRRA
CEEEEEEEEECCCEEEEEECHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
VSAPLAEVAGVARRVAAGDLTHRFSGTRRDEIGQLMHAINGLGDGLSGIVDKVRASASTI
HHCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
ASSTGQIAAGNVDLSARTEAQAGNLERTASSIEQLAATVRQNADSAQHAHDMVQSASEAA
HCCCCCEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
NAGGRTVARLVGTMSGIHTTAQKIADITGIIDGIAFQTNILALNAAVEAARAGEQGRGFA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEE
VVAGEVRSLAQRSAAAAKEIKELISRSVQEVQAGNEAARGAGEAMQDIVTRVERIAGIMG
EEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
EISHASREQSQGIEEVNRAVTSMDEVTQQNAALVEEAAAAAESLRQQAQELRGAVDVFRL
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
A
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8419927; 11677609 [H]