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The map label for this gene is mocR [H]

Identifier: 17547838

GI number: 17547838

Start: 3358523

End: 3359989

Strand: Reverse

Name: mocR [H]

Synonym: RSc3119

Alternate gene names: 17547838

Gene position: 3359989-3358523 (Counterclockwise)

Preceding gene: 17547842

Following gene: 17547824

Centisome position: 90.41

GC content: 72.73

Gene sequence:

>1467_bases
ATGGACTACGGTGTCCTGCTGTCGACCTACGAACGCGAGACCGGCCGCGAGGCAATCGCCCGGATGCCCCAGCAGCATCG
GCTGTACGCCTGCCTGCGCGCCGCCATCCTGAGCGGCAAGCTCGAGGAAGGCACGCGGCTGCTGGCGTCGCGCACGCTGG
CCGAGGAGCTGGGCATGGCCCGCAACTCGGTGCTGTATGCGTACGAACGGCTGGCGTCCGAGGGTTTCGTCGTCGGGCGG
CGGCAGGGTACGGTGGTCGCCCGCGTGGGCCTGCAGCAGTCGCCCGCCGCCACGCCCGGCGATGCGCCCGTCCTGTCGCG
GCGCGTCGCCCGGATCGAACGCCCCGGCGACGGCATGGACGATCCGCTGCCCTTCCTGCCCGGCACGCCCGCGCTGGGTG
CCTTTCCGCTCGCGCAATGGCGGCGCTGCGTGGAGCGCGCCTGGCGCAGCATCGGCCCGGCGCAGCTCGGCTACATGCCG
GTCGAAGGCAACGCTGCCCTGCGCCAGGCGATCGCCGAATACCTGCGCGTCTCGCGCGGCGTGCGCTGCGAGGCCAGGCA
GGTTTTCATCACCGACGGCACGCAGAACAGCCTCGACCTGTGCGCCCGCACCCTGGCCGATGCCGATGACACCGCCTGGA
TCGAAAACCCCGGCTACAGCGGCGCGCGCCACGCCTTCCAGGCCGCCAACCTGCGGCTGGCGCCGATCCCGGTCGATGCC
GACGGGCTCGCGCCACGGCCGGAGGACTGGCGCGACCGTCCGCCCAGGCTGATCTACATCACGCCGTCGCACCAGTACCC
GCTCGGCGCCGTGATGAGCCTGGAGCGGCGGCTGGCGCTGCTGGCCCAGGCGCGCGCGGCCGGCGCGTGGATCATCGAAG
ACGACTACGACAGCGAATTCCGTCACCAGGGCGCGCCGCTGTCCGCGGTGCAGGGATTGACCGAAGACGCGCCGGTGATC
TATCTCGGCACCTTCAGCAAGGTGATGTTCCCGGCGCTGCGGCTCGGCTTCATGGTGGTGCCGCCCGCGCTGGCGCCGGT
GTTGCGGCGCACGGCCGGCGCGCTGATGCTGCGCGGGCGGGTGGCGGAGCAGCTCGCGCTGGCGGACTTCATCGACGCCG
GGCATTTCACGCGGCACCTGCGGCGCATGCGGCGGCTGTATGCGGAGCGGCGCGACGCGTTGCAAGGCGCGCTCGAACGC
CGGCTGCGCGGCCTGCTGACCGTGTCCGGCGGGGCCGGCGGCATGCATCTGTCGGCACGGCTCGACGTGCCGGTGCGGGA
TACCGAGGTCAGCCGCGTAGGCCGAGCACACGGGCTGGTGCTGCGGCCGCTGTCGCGGTTCTGCCTGCCGGGCACCGAAG
GCCCCTACAACGGTCTGGTGCTCGGCTACGGCGCGGTGGATGCCGGGCGGATGGACCGGCTGGTCCAGCAGCTCGGGCAG
GTGATCGAGGCAGCGCTGGCGGGATGA

Upstream 100 bases:

>100_bases
TCATGGTGGGGCTCCTCTCACGGGCAATGGCATGCCTCGACGATAGGAAAACCATGGCACCATGCGTAGACCCACACGAT
GATGGATTCATGGAGCCACA

Downstream 100 bases:

>100_bases
TGCCGCCGCCGCCCAGGCAGGGAATCGTCAGTGCACCAGCTGATTGATCTCGATGATCGGCATCAGCACCGCCAGCACGA
TCAGCAGCACCACCACCCCC

Product: transcription regulator protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 488; Mature: 488

Protein sequence:

>488_residues
MDYGVLLSTYERETGREAIARMPQQHRLYACLRAAILSGKLEEGTRLLASRTLAEELGMARNSVLYAYERLASEGFVVGR
RQGTVVARVGLQQSPAATPGDAPVLSRRVARIERPGDGMDDPLPFLPGTPALGAFPLAQWRRCVERAWRSIGPAQLGYMP
VEGNAALRQAIAEYLRVSRGVRCEARQVFITDGTQNSLDLCARTLADADDTAWIENPGYSGARHAFQAANLRLAPIPVDA
DGLAPRPEDWRDRPPRLIYITPSHQYPLGAVMSLERRLALLAQARAAGAWIIEDDYDSEFRHQGAPLSAVQGLTEDAPVI
YLGTFSKVMFPALRLGFMVVPPALAPVLRRTAGALMLRGRVAEQLALADFIDAGHFTRHLRRMRRLYAERRDALQGALER
RLRGLLTVSGGAGGMHLSARLDVPVRDTEVSRVGRAHGLVLRPLSRFCLPGTEGPYNGLVLGYGAVDAGRMDRLVQQLGQ
VIEAALAG

Sequences:

>Translated_488_residues
MDYGVLLSTYERETGREAIARMPQQHRLYACLRAAILSGKLEEGTRLLASRTLAEELGMARNSVLYAYERLASEGFVVGR
RQGTVVARVGLQQSPAATPGDAPVLSRRVARIERPGDGMDDPLPFLPGTPALGAFPLAQWRRCVERAWRSIGPAQLGYMP
VEGNAALRQAIAEYLRVSRGVRCEARQVFITDGTQNSLDLCARTLADADDTAWIENPGYSGARHAFQAANLRLAPIPVDA
DGLAPRPEDWRDRPPRLIYITPSHQYPLGAVMSLERRLALLAQARAAGAWIIEDDYDSEFRHQGAPLSAVQGLTEDAPVI
YLGTFSKVMFPALRLGFMVVPPALAPVLRRTAGALMLRGRVAEQLALADFIDAGHFTRHLRRMRRLYAERRDALQGALER
RLRGLLTVSGGAGGMHLSARLDVPVRDTEVSRVGRAHGLVLRPLSRFCLPGTEGPYNGLVLGYGAVDAGRMDRLVQQLGQ
VIEAALAG
>Mature_488_residues
MDYGVLLSTYERETGREAIARMPQQHRLYACLRAAILSGKLEEGTRLLASRTLAEELGMARNSVLYAYERLASEGFVVGR
RQGTVVARVGLQQSPAATPGDAPVLSRRVARIERPGDGMDDPLPFLPGTPALGAFPLAQWRRCVERAWRSIGPAQLGYMP
VEGNAALRQAIAEYLRVSRGVRCEARQVFITDGTQNSLDLCARTLADADDTAWIENPGYSGARHAFQAANLRLAPIPVDA
DGLAPRPEDWRDRPPRLIYITPSHQYPLGAVMSLERRLALLAQARAAGAWIIEDDYDSEFRHQGAPLSAVQGLTEDAPVI
YLGTFSKVMFPALRLGFMVVPPALAPVLRRTAGALMLRGRVAEQLALADFIDAGHFTRHLRRMRRLYAERRDALQGALER
RLRGLLTVSGGAGGMHLSARLDVPVRDTEVSRVGRAHGLVLRPLSRFCLPGTEGPYNGLVLGYGAVDAGRMDRLVQQLGQ
VIEAALAG

Specific function: Could play a regulatory role in the transcription of the moc genes for rhizopine catabolism. Could also have an aminotransferase activity [H]

COG id: COG1167

COG function: function code KE; Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Homo sapiens, GI7705897, Length=317, Percent_Identity=23.6593059936909, Blast_Score=86, Evalue=1e-16,
Organism=Homo sapiens, GI33469970, Length=317, Percent_Identity=23.6593059936909, Blast_Score=86, Evalue=1e-16,
Organism=Escherichia coli, GI1787710, Length=477, Percent_Identity=27.0440251572327, Blast_Score=122, Evalue=6e-29,
Organism=Escherichia coli, GI1790797, Length=381, Percent_Identity=27.2965879265092, Blast_Score=110, Evalue=2e-25,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR000524
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00155 Aminotran_1_2; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 53334; Mature: 53334

Theoretical pI: Translated: 9.68; Mature: 9.68

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDYGVLLSTYERETGREAIARMPQQHRLYACLRAAILSGKLEEGTRLLASRTLAEELGMA
CCCCCEEHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCH
RNSVLYAYERLASEGFVVGRRQGTVVARVGLQQSPAATPGDAPVLSRRVARIERPGDGMD
HHHHHHHHHHHHCCCEEEECCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHCCCCCCCC
DPLPFLPGTPALGAFPLAQWRRCVERAWRSIGPAQLGYMPVEGNAALRQAIAEYLRVSRG
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHCCEECCCCHHHHHHHHHHHHHHCC
VRCEARQVFITDGTQNSLDLCARTLADADDTAWIENPGYSGARHAFQAANLRLAPIPVDA
CCCCCEEEEEECCCCCHHHHHHHHHCCCCCCCEECCCCCCHHHHHHHHCCEEEECCCCCC
DGLAPRPEDWRDRPPRLIYITPSHQYPLGAVMSLERRLALLAQARAAGAWIIEDDYDSEF
CCCCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCEEEEECCCCHHH
RHQGAPLSAVQGLTEDAPVIYLGTFSKVMFPALRLGFMVVPPALAPVLRRTAGALMLRGR
HHCCCCHHHHHCCCCCCCEEEECCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
VAEQLALADFIDAGHFTRHLRRMRRLYAERRDALQGALERRLRGLLTVSGGAGGMHLSAR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCEEEEEE
LDVPVRDTEVSRVGRAHGLVLRPLSRFCLPGTEGPYNGLVLGYGAVDAGRMDRLVQQLGQ
ECCCCCCHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHH
VIEAALAG
HHHHHHCC
>Mature Secondary Structure
MDYGVLLSTYERETGREAIARMPQQHRLYACLRAAILSGKLEEGTRLLASRTLAEELGMA
CCCCCEEHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCH
RNSVLYAYERLASEGFVVGRRQGTVVARVGLQQSPAATPGDAPVLSRRVARIERPGDGMD
HHHHHHHHHHHHCCCEEEECCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHCCCCCCCC
DPLPFLPGTPALGAFPLAQWRRCVERAWRSIGPAQLGYMPVEGNAALRQAIAEYLRVSRG
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHCCEECCCCHHHHHHHHHHHHHHCC
VRCEARQVFITDGTQNSLDLCARTLADADDTAWIENPGYSGARHAFQAANLRLAPIPVDA
CCCCCEEEEEECCCCCHHHHHHHHHCCCCCCCEECCCCCCHHHHHHHHCCEEEECCCCCC
DGLAPRPEDWRDRPPRLIYITPSHQYPLGAVMSLERRLALLAQARAAGAWIIEDDYDSEF
CCCCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCEEEEECCCCHHH
RHQGAPLSAVQGLTEDAPVIYLGTFSKVMFPALRLGFMVVPPALAPVLRRTAGALMLRGR
HHCCCCHHHHHCCCCCCCEEEECCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
VAEQLALADFIDAGHFTRHLRRMRRLYAERRDALQGALERRLRGLLTVSGGAGGMHLSAR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCEEEEEE
LDVPVRDTEVSRVGRAHGLVLRPLSRFCLPGTEGPYNGLVLGYGAVDAGRMDRLVQQLGQ
ECCCCCCHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHH
VIEAALAG
HHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7845353 [H]