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The map label for this gene is manA [H]

Identifier: 17547777

GI number: 17547777

Start: 3294747

End: 3295979

Strand: Direct

Name: manA [H]

Synonym: RSc3058

Alternate gene names: 17547777

Gene position: 3294747-3295979 (Clockwise)

Preceding gene: 17547773

Following gene: 17547778

Centisome position: 88.65

GC content: 71.29

Gene sequence:

>1233_bases
ATGCTTCCATCGTTCTCGACGTCCGTCCTACCTGGCACCATCGAACTGCCCGACGCGGCTGCCGCGCTGGAGGCGTTCGC
CCGCCATTACGACGATGTCCTACTGCCGATGTGGCTCGGTCCGGGCTGGAACGCGCAGGCCGGCCTGTGCTACGAGGCGC
TGGTCGCCGAGGGCGACCGCCTGGTGCCGGCCACCACGTCGCGCTACCGCGCCATGGCGTGCGCCCGGCAGCTGTACACG
TTCGCCCGCGCAAGCGTGCTGTCCAAGCGGCATGCCGCGGTCTGCGCCGAGCGCGCCGCGGCGCTGTGCCATGCGCTGGA
CACGCGCTTCCGCGACACGATCCACGGCGGCTGGCTGTTCGCCATCGACAGCGCGCTGGCGCCGCAGGACACCACCAAGG
ACCTGTACACGCACGCCTTCGTGCTGTTCGCCGCCGCGCACTGGCTAGCCGTGAGCGACGATCCGCGCGCCGCGGCGCTG
ATGGAAGAGGCGCATGACGTCGTCTCCCGCCGCTTTGCGCGCGAGGGCGCCATGCCGCTGCCGGTGGCCGCCATGGACGC
GGCCTTCGCCGCGCCGCTGGCCGGCGTCGAGCAGAACCCGGTGATGCACCTGACCGAGGCCTACCTGGCCGCGGCCGCCC
TGCCCGATGCGCCCGCCTGGGCCGAGGCCGGCGTGCACGCGCTGGCCGAAGGCATGGCCGCGCGCTTCATCGATGCGCGC
ACCGGCTGCATCGCCGAACTGCCGGTCGACCAGGCCGACACGGACAACCGCATCGAACCCGGTCACCAGTTCGAATGGTT
TTACCTGGTGCGCGCGCACGCCGACGTGTTCACCCGCTCCGAGCCCGGCCGGCAGCTGGCCGACACGCTGGGCCGCGCGG
TCGACACCGCCTGCCGCCTGGGCGTGGACGCCAAGACCCAGGGCGTCTGCCTGTCGCTGGAACTGGATGGCGGCATGCGC
GACGCCAGCCAGCGCATCTGGGCACAGACCGAATATGGTCGCGCGCTGTCGCTGTGCAGCGAAACCCACGGCACGCTGCT
GGCCAGCACGCTGTCGCTGTGGTCGGCGCGCTTCCTCCATGAGCGTGGCTGGCATGAGGTGATCGACGCGACGGGCCGGC
GCCTGCGCGACGACATGCCCTCCAGCACGCCATACCACATCACGACTTTCTACGAGGCGGTCCGCGCTGCACTGGCGGCC
CGCCCGACTGTTGTACCCCAAGCTGTTGAGTGA

Upstream 100 bases:

>100_bases
TATTGAAATTGGGCCGCGTAGCGTCCCCCCGCCAGTTGGCGCACAATCTAGGCCCGCCGGCGCTGTATCGCCGGCTTTCG
CCATGACAGTCCCGGCGCAC

Downstream 100 bases:

>100_bases
GACATCCATGCATACCCACAACCCCAACGAATCCAAGGCCCGTTCCATCTTCCGGGTGGTCAGCGGTAACTTCCTGGAGA
TGTACGACTTCATGGTCTAC

Product: mannose-6-phosphate isomerase

Products: NA

Alternate protein names: Phosphohexomutase; Phosphomannose isomerase; PMI [H]

Number of amino acids: Translated: 410; Mature: 410

Protein sequence:

>410_residues
MLPSFSTSVLPGTIELPDAAAALEAFARHYDDVLLPMWLGPGWNAQAGLCYEALVAEGDRLVPATTSRYRAMACARQLYT
FARASVLSKRHAAVCAERAAALCHALDTRFRDTIHGGWLFAIDSALAPQDTTKDLYTHAFVLFAAAHWLAVSDDPRAAAL
MEEAHDVVSRRFAREGAMPLPVAAMDAAFAAPLAGVEQNPVMHLTEAYLAAAALPDAPAWAEAGVHALAEGMAARFIDAR
TGCIAELPVDQADTDNRIEPGHQFEWFYLVRAHADVFTRSEPGRQLADTLGRAVDTACRLGVDAKTQGVCLSLELDGGMR
DASQRIWAQTEYGRALSLCSETHGTLLASTLSLWSARFLHERGWHEVIDATGRRLRDDMPSSTPYHITTFYEAVRAALAA
RPTVVPQAVE

Sequences:

>Translated_410_residues
MLPSFSTSVLPGTIELPDAAAALEAFARHYDDVLLPMWLGPGWNAQAGLCYEALVAEGDRLVPATTSRYRAMACARQLYT
FARASVLSKRHAAVCAERAAALCHALDTRFRDTIHGGWLFAIDSALAPQDTTKDLYTHAFVLFAAAHWLAVSDDPRAAAL
MEEAHDVVSRRFAREGAMPLPVAAMDAAFAAPLAGVEQNPVMHLTEAYLAAAALPDAPAWAEAGVHALAEGMAARFIDAR
TGCIAELPVDQADTDNRIEPGHQFEWFYLVRAHADVFTRSEPGRQLADTLGRAVDTACRLGVDAKTQGVCLSLELDGGMR
DASQRIWAQTEYGRALSLCSETHGTLLASTLSLWSARFLHERGWHEVIDATGRRLRDDMPSSTPYHITTFYEAVRAALAA
RPTVVPQAVE
>Mature_410_residues
MLPSFSTSVLPGTIELPDAAAALEAFARHYDDVLLPMWLGPGWNAQAGLCYEALVAEGDRLVPATTSRYRAMACARQLYT
FARASVLSKRHAAVCAERAAALCHALDTRFRDTIHGGWLFAIDSALAPQDTTKDLYTHAFVLFAAAHWLAVSDDPRAAAL
MEEAHDVVSRRFAREGAMPLPVAAMDAAFAAPLAGVEQNPVMHLTEAYLAAAALPDAPAWAEAGVHALAEGMAARFIDAR
TGCIAELPVDQADTDNRIEPGHQFEWFYLVRAHADVFTRSEPGRQLADTLGRAVDTACRLGVDAKTQGVCLSLELDGGMR
DASQRIWAQTEYGRALSLCSETHGTLLASTLSLWSARFLHERGWHEVIDATGRRLRDDMPSSTPYHITTFYEAVRAALAA
RPTVVPQAVE

Specific function: Unknown

COG id: COG2942

COG function: function code G; N-acyl-D-glucosamine 2-epimerase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the N-acylglucosamine 2-epimerase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008928
- InterPro:   IPR012341
- InterPro:   IPR010819 [H]

Pfam domain/function: PF07221 GlcNAc_2-epim [H]

EC number: =5.3.1.8 [H]

Molecular weight: Translated: 44481; Mature: 44481

Theoretical pI: Translated: 5.53; Mature: 5.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLPSFSTSVLPGTIELPDAAAALEAFARHYDDVLLPMWLGPGWNAQAGLCYEALVAEGDR
CCCCCCCCCCCCCEECCHHHHHHHHHHHHHCCEEEEEEECCCCCCCCCHHHHHHHHCCCE
LVPATTSRYRAMACARQLYTFARASVLSKRHAAVCAERAAALCHALDTRFRDTIHGGWLF
ECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEE
AIDSALAPQDTTKDLYTHAFVLFAAAHWLAVSDDPRAAALMEEAHDVVSRRFAREGAMPL
EECCCCCCCCCHHHHHHHHHHHHHHHHHHEECCCCHHHHHHHHHHHHHHHHHHHCCCCCC
PVAAMDAAFAAPLAGVEQNPVMHLTEAYLAAAALPDAPAWAEAGVHALAEGMAARFIDAR
CHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHC
TGCIAELPVDQADTDNRIEPGHQFEWFYLVRAHADVFTRSEPGRQLADTLGRAVDTACRL
CCCEEECCCCCCCCCCCCCCCCCEEEEEEEEEHHHHHCCCCCCHHHHHHHHHHHHHHHHC
GVDAKTQGVCLSLELDGGMRDASQRIWAQTEYGRALSLCSETHGTLLASTLSLWSARFLH
CCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ERGWHEVIDATGRRLRDDMPSSTPYHITTFYEAVRAALAARPTVVPQAVE
HCCHHHHHHHHHHHHHHCCCCCCCEEHHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MLPSFSTSVLPGTIELPDAAAALEAFARHYDDVLLPMWLGPGWNAQAGLCYEALVAEGDR
CCCCCCCCCCCCCEECCHHHHHHHHHHHHHCCEEEEEEECCCCCCCCCHHHHHHHHCCCE
LVPATTSRYRAMACARQLYTFARASVLSKRHAAVCAERAAALCHALDTRFRDTIHGGWLF
ECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEE
AIDSALAPQDTTKDLYTHAFVLFAAAHWLAVSDDPRAAALMEEAHDVVSRRFAREGAMPL
EECCCCCCCCCHHHHHHHHHHHHHHHHHHEECCCCHHHHHHHHHHHHHHHHHHHCCCCCC
PVAAMDAAFAAPLAGVEQNPVMHLTEAYLAAAALPDAPAWAEAGVHALAEGMAARFIDAR
CHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHC
TGCIAELPVDQADTDNRIEPGHQFEWFYLVRAHADVFTRSEPGRQLADTLGRAVDTACRL
CCCEEECCCCCCCCCCCCCCCCCEEEEEEEEEHHHHHCCCCCCHHHHHHHHHHHHHHHHC
GVDAKTQGVCLSLELDGGMRDASQRIWAQTEYGRALSLCSETHGTLLASTLSLWSARFLH
CCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ERGWHEVIDATGRRLRDDMPSSTPYHITTFYEAVRAALAARPTVVPQAVE
HCCHHHHHHHHHHHHHHCCCCCCCEEHHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1452036; 11481430 [H]