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The map label for this gene is glpR [H]

Identifier: 17547763

GI number: 17547763

Start: 3280710

End: 3281495

Strand: Reverse

Name: glpR [H]

Synonym: RSc3044

Alternate gene names: 17547763

Gene position: 3281495-3280710 (Counterclockwise)

Preceding gene: 17547772

Following gene: 17547762

Centisome position: 88.3

GC content: 65.78

Gene sequence:

>786_bases
ATGTTCGTTTGTGTTCGTTTGATGCTTCCCCGCCACCGCCAGATCCTCGAATACGTCCGCCAGCACGGCGACGCCACCGT
CGATGCGCTTGCCCGCGTGCTCGGCGTCACCGCGCAGACCATCCGCCGCGACATTCGCCAGCTCGAAGACGAGCGGCTGC
TCGCGCGCTACCACGGCGGCGTGGGCCTGCCGTCGTCGGTCGAAAACATCGACTACGACCAGCGCCAGGTCCTGCACATC
GACGCCAAGCGCCGCATCGCCGAGGTCGTCGCCCGCCATATCGAGCCGGGCCGCTCGCTGATCATCAACATCGGCACCAC
GACGGAAGAGATCTCCAAGGCATTGGTGGGGCGCAAGGGGTTGCGCGTCATCACCAATAACCTGAACGTCGCGTCCATCC
TGTCGGGCAGCCCTGACGCGGAGGTGATCGTCGCCGGCGGCCTGGTGCGCAACCGCGATCGCGGCATCGTGGGCGAGGCC
ACCATCGATTTCATGAAGCAGTTCCGCGTCGACGTCGGCATCATCGGCGTCTCCAGCATCGACGAGGACGGCACGCTGCT
CGATTACGACTACCGCGAGGTGCGCGTCGCCCAGACCATCATCGAGCAGTCGCGTGAGGTCTGGCTCGCCGCCGACCACT
CCAAGTTCGGCCGTCGCGCGGTCGTGCGCCTGGGGCACATCTCGCAGATCGACAAGTTTTTCACCGATCTTCCGGTTCCC
GAGCCGATGGTCGAAGTCTTCCGCGCGGCCGAAGTGGAGGTCGTCGTCGCCAGCGAGGTCGGCTGA

Upstream 100 bases:

>100_bases
TGATTTGCGCGTCTTTTGTTGCGAATAGTGACGCGTTGGCGGATAGTGTAGTGAAAGGCGAAAATAAAGCAACATAGGGA
ATCGCCTGATCTGCTCACAT

Downstream 100 bases:

>100_bases
CGCTGGCAGTGCCGATGCCTTCGACTACAGTGAAATGACGGCGCACACACCCGGTGCGTCCGGCGCATTGCCTGCATCGT
CGATGCCTCTCGGGGAGAGG

Product: glycerol-3-phosphate regulon repressor transcription regulator protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 261; Mature: 261

Protein sequence:

>261_residues
MFVCVRLMLPRHRQILEYVRQHGDATVDALARVLGVTAQTIRRDIRQLEDERLLARYHGGVGLPSSVENIDYDQRQVLHI
DAKRRIAEVVARHIEPGRSLIINIGTTTEEISKALVGRKGLRVITNNLNVASILSGSPDAEVIVAGGLVRNRDRGIVGEA
TIDFMKQFRVDVGIIGVSSIDEDGTLLDYDYREVRVAQTIIEQSREVWLAADHSKFGRRAVVRLGHISQIDKFFTDLPVP
EPMVEVFRAAEVEVVVASEVG

Sequences:

>Translated_261_residues
MFVCVRLMLPRHRQILEYVRQHGDATVDALARVLGVTAQTIRRDIRQLEDERLLARYHGGVGLPSSVENIDYDQRQVLHI
DAKRRIAEVVARHIEPGRSLIINIGTTTEEISKALVGRKGLRVITNNLNVASILSGSPDAEVIVAGGLVRNRDRGIVGEA
TIDFMKQFRVDVGIIGVSSIDEDGTLLDYDYREVRVAQTIIEQSREVWLAADHSKFGRRAVVRLGHISQIDKFFTDLPVP
EPMVEVFRAAEVEVVVASEVG
>Mature_261_residues
MFVCVRLMLPRHRQILEYVRQHGDATVDALARVLGVTAQTIRRDIRQLEDERLLARYHGGVGLPSSVENIDYDQRQVLHI
DAKRRIAEVVARHIEPGRSLIINIGTTTEEISKALVGRKGLRVITNNLNVASILSGSPDAEVIVAGGLVRNRDRGIVGEA
TIDFMKQFRVDVGIIGVSSIDEDGTLLDYDYREVRVAQTIIEQSREVWLAADHSKFGRRAVVRLGHISQIDKFFTDLPVP
EPMVEVFRAAEVEVVVASEVG

Specific function: Repressor of the glycerol-3-phosphate regulon [H]

COG id: COG1349

COG function: function code KG; Transcriptional regulators of sugar metabolism

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH deoR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789829, Length=244, Percent_Identity=46.7213114754098, Blast_Score=236, Evalue=1e-63,
Organism=Escherichia coli, GI87082344, Length=250, Percent_Identity=38.8, Blast_Score=203, Evalue=1e-53,
Organism=Escherichia coli, GI1788069, Length=228, Percent_Identity=31.140350877193, Blast_Score=111, Evalue=5e-26,
Organism=Escherichia coli, GI1789519, Length=252, Percent_Identity=27.3809523809524, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI1789059, Length=256, Percent_Identity=28.515625, Blast_Score=108, Evalue=3e-25,
Organism=Escherichia coli, GI226510968, Length=253, Percent_Identity=28.8537549407115, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI1790753, Length=253, Percent_Identity=26.0869565217391, Blast_Score=97, Evalue=9e-22,
Organism=Escherichia coli, GI1787540, Length=230, Percent_Identity=27.3913043478261, Blast_Score=93, Evalue=1e-20,
Organism=Escherichia coli, GI1789170, Length=232, Percent_Identity=24.1379310344828, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI1787063, Length=231, Percent_Identity=24.2424242424242, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1790635, Length=231, Percent_Identity=26.4069264069264, Blast_Score=67, Evalue=1e-12,

Paralogues:

None

Copy number: 900 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014036
- InterPro:   IPR001034
- InterPro:   IPR018356
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00455 DeoR; PF08220 HTH_DeoR [H]

EC number: NA

Molecular weight: Translated: 29108; Mature: 29108

Theoretical pI: Translated: 6.64; Mature: 6.64

Prosite motif: PS00894 HTH_DEOR_1 ; PS51000 HTH_DEOR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFVCVRLMLPRHRQILEYVRQHGDATVDALARVLGVTAQTIRRDIRQLEDERLLARYHGG
CEEEEEECCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
VGLPSSVENIDYDQRQVLHIDAKRRIAEVVARHIEPGRSLIINIGTTTEEISKALVGRKG
CCCCCCCCCCCCCCHHEEEHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHCCCC
LRVITNNLNVASILSGSPDAEVIVAGGLVRNRDRGIVGEATIDFMKQFRVDVGIIGVSSI
CEEEECCCCEEEEECCCCCCEEEEECCEEECCCCCCCCHHHHHHHHHHHHHHEEEEECCC
DEDGTLLDYDYREVRVAQTIIEQSREVWLAADHSKFGRRAVVRLGHISQIDKFFTDLPVP
CCCCCEEECCHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCCC
EPMVEVFRAAEVEVVVASEVG
CHHHHHHHHCCEEEEEECCCC
>Mature Secondary Structure
MFVCVRLMLPRHRQILEYVRQHGDATVDALARVLGVTAQTIRRDIRQLEDERLLARYHGG
CEEEEEECCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
VGLPSSVENIDYDQRQVLHIDAKRRIAEVVARHIEPGRSLIINIGTTTEEISKALVGRKG
CCCCCCCCCCCCCCHHEEEHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHCCCC
LRVITNNLNVASILSGSPDAEVIVAGGLVRNRDRGIVGEATIDFMKQFRVDVGIIGVSSI
CEEEECCCCEEEEECCCCCCEEEEECCEEECCCCCCCCHHHHHHHHHHHHHHEEEEECCC
DEDGTLLDYDYREVRVAQTIIEQSREVWLAADHSKFGRRAVVRLGHISQIDKFFTDLPVP
CCCCCEEECCHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCCC
EPMVEVFRAAEVEVVVASEVG
CHHHHHHHHCCEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8752340; 10984043 [H]