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The map label for this gene is secY [H]

Identifier: 17547718

GI number: 17547718

Start: 3229331

End: 3230677

Strand: Reverse

Name: secY [H]

Synonym: RSc2999

Alternate gene names: 17547718

Gene position: 3230677-3229331 (Counterclockwise)

Preceding gene: 17547719

Following gene: 17547717

Centisome position: 86.93

GC content: 59.99

Gene sequence:

>1347_bases
TTGGCCACGGCGAAACCTAATGTGATGGCGCAGGCCAAGAACACGGCCAAGTACGGCGATCTTCGCCGTCGGCTGGTGTT
CTTGGTCCTGGCACTGCTGGTGTACCGGATCGGCGCGCACATCCCTGTGCCTGGCATCGATCCGGACCAACTGGCGCAGC
TTTTCCAACGGCAGTCGGGTGGCATCCTCGGGATGTTCAACCTGTTCTCCGGCGGCGCGCTCTCGCGCTTCACGGTATTT
GCGCTGGGGATCATGCCGTATATCTCGGCATCGATCATCATGCAGCTGCTGACGATCGTGTTGCCGCAGCTGGAGTCGCT
GAAGAAGGAAGGGCAGGCTGGCCAGCGCAAGATTACGCAATACACGCGCTACGGTACGGTCGTCCTGGCGACTTTCCAGG
CGCTGGGCATCGCGGTGGCGCTTGAGGCGCAGCCTGGTCTGGTGCTGGACCCGGGCCTGATGTTCCGGGCGACGGCCGTG
ATCACGCTGGTGACGGGCACGATGTTCCTGATGTGGCTGGGTGAGCAGATCACCGAGCGCGGTCTGGGCAACGGCATCTC
GATCATCATCTTTGGCGGGATCGCAGCAGGGTTGCCCAACGCCATCGGCGGGCTGTTCGAACTGGTGCGCACGGGGTCGA
TGGGAATTTTCTCCGCGATTCTGGTAGTGGCGATCATTGGCGCGGTGACGTTCCTGGTGGTGTTCATCGAACGCGGCCAG
CGCAAGATCCTCGTCAACTATGCCAAGCGGCAGGTCGGTAACAAGATCTATGGCGGTCAGTCGTCGCATCTGCCGCTGAA
GTTGAACATGGCTGGGGTGATTCCGCCGATCTTCGCATCGTCGATCATTCTGTTCCCGGCCACGATCGCGGGCTGGTTCA
CTGCCGGCAACTCGACGAATCCGGTTGCACGGTTCGTCAAGGATCTGGCGTCGACGCTGTCGCCGGGCCAGCCGGTGTAC
ATCCTGCTGTATGCGGCGGCAATCATCTTCTTCTGCTTCTTCTACACCGCGCTGGTCTATAACAGCCGCGAAGTGGCGGA
TAACCTGAAGAAGAGTGGGGCGTTCATTCCGGGGATCCGCCCGGGTGAGCAAACCACGCGGTATATCGACAAGATTCTGG
TGCGTCTGACCCTGGCTGGTGCGATTTACATCACGCTGGTGTGTCTGTTGCCGGAGTTCTTGGTACTGCGCTGGAACGTG
CCGTTCTACTTCGGTGGAACGTCGCTGCTGATCATCGTGGTTGTCACGATGGACTTCATGGCGCAGGTGCAGTCGTACGT
GATGTCTCAGCAGTACGAGTCTTTGATGAAGAAGGCGAATTTCAAGGGCAACCTGACGCTCCGTTAG

Upstream 100 bases:

>100_bases
TGAAGGGCCTGGGCGCGACGGCTGGGGCGAAGGCCGCAATCGAAGCGGCTGGTGGCTCGCTGGCGTAAAGCCTGCTGTTT
GACACTGTCGGAGCATCCGT

Downstream 100 bases:

>100_bases
CTAGGGCGATCGCACGAAGCTGAAGAGACATGGCTAAAGACGACGTGATCCAGATGCAGGGCGAGGTGCAGGAAAACCTC
CCCAACGCGACGTTCCGCGT

Product: preprotein translocase subunit SecY

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 448; Mature: 447

Protein sequence:

>448_residues
MATAKPNVMAQAKNTAKYGDLRRRLVFLVLALLVYRIGAHIPVPGIDPDQLAQLFQRQSGGILGMFNLFSGGALSRFTVF
ALGIMPYISASIIMQLLTIVLPQLESLKKEGQAGQRKITQYTRYGTVVLATFQALGIAVALEAQPGLVLDPGLMFRATAV
ITLVTGTMFLMWLGEQITERGLGNGISIIIFGGIAAGLPNAIGGLFELVRTGSMGIFSAILVVAIIGAVTFLVVFIERGQ
RKILVNYAKRQVGNKIYGGQSSHLPLKLNMAGVIPPIFASSIILFPATIAGWFTAGNSTNPVARFVKDLASTLSPGQPVY
ILLYAAAIIFFCFFYTALVYNSREVADNLKKSGAFIPGIRPGEQTTRYIDKILVRLTLAGAIYITLVCLLPEFLVLRWNV
PFYFGGTSLLIIVVVTMDFMAQVQSYVMSQQYESLMKKANFKGNLTLR

Sequences:

>Translated_448_residues
MATAKPNVMAQAKNTAKYGDLRRRLVFLVLALLVYRIGAHIPVPGIDPDQLAQLFQRQSGGILGMFNLFSGGALSRFTVF
ALGIMPYISASIIMQLLTIVLPQLESLKKEGQAGQRKITQYTRYGTVVLATFQALGIAVALEAQPGLVLDPGLMFRATAV
ITLVTGTMFLMWLGEQITERGLGNGISIIIFGGIAAGLPNAIGGLFELVRTGSMGIFSAILVVAIIGAVTFLVVFIERGQ
RKILVNYAKRQVGNKIYGGQSSHLPLKLNMAGVIPPIFASSIILFPATIAGWFTAGNSTNPVARFVKDLASTLSPGQPVY
ILLYAAAIIFFCFFYTALVYNSREVADNLKKSGAFIPGIRPGEQTTRYIDKILVRLTLAGAIYITLVCLLPEFLVLRWNV
PFYFGGTSLLIIVVVTMDFMAQVQSYVMSQQYESLMKKANFKGNLTLR
>Mature_447_residues
ATAKPNVMAQAKNTAKYGDLRRRLVFLVLALLVYRIGAHIPVPGIDPDQLAQLFQRQSGGILGMFNLFSGGALSRFTVFA
LGIMPYISASIIMQLLTIVLPQLESLKKEGQAGQRKITQYTRYGTVVLATFQALGIAVALEAQPGLVLDPGLMFRATAVI
TLVTGTMFLMWLGEQITERGLGNGISIIIFGGIAAGLPNAIGGLFELVRTGSMGIFSAILVVAIIGAVTFLVVFIERGQR
KILVNYAKRQVGNKIYGGQSSHLPLKLNMAGVIPPIFASSIILFPATIAGWFTAGNSTNPVARFVKDLASTLSPGQPVYI
LLYAAAIIFFCFFYTALVYNSREVADNLKKSGAFIPGIRPGEQTTRYIDKILVRLTLAGAIYITLVCLLPEFLVLRWNVP
FYFGGTSLLIIVVVTMDFMAQVQSYVMSQQYESLMKKANFKGNLTLR

Specific function: Involved in protein export. Interacts with secA and secE to allow the translocation of proteins across the plasma membrane, by forming part of a channel [H]

COG id: COG0201

COG function: function code U; Preprotein translocase subunit SecY

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the secY/SEC61-alpha family [H]

Homologues:

Organism=Escherichia coli, GI1789696, Length=428, Percent_Identity=66.1214953271028, Blast_Score=533, Evalue=1e-152,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002208
- InterPro:   IPR023201 [H]

Pfam domain/function: PF00344 SecY [H]

EC number: NA

Molecular weight: Translated: 48713; Mature: 48582

Theoretical pI: Translated: 10.42; Mature: 10.42

Prosite motif: PS00755 SECY_1 ; PS00756 SECY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATAKPNVMAQAKNTAKYGDLRRRLVFLVLALLVYRIGAHIPVPGIDPDQLAQLFQRQSG
CCCCCCCHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCC
GILGMFNLFSGGALSRFTVFALGIMPYISASIIMQLLTIVLPQLESLKKEGQAGQRKITQ
CEEEEHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
YTRYGTVVLATFQALGIAVALEAQPGLVLDPGLMFRATAVITLVTGTMFLMWLGEQITER
HHHHHHHHHHHHHHHCEEEEEECCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GLGNGISIIIFGGIAAGLPNAIGGLFELVRTGSMGIFSAILVVAIIGAVTFLVVFIERGQ
CCCCCCEEEEECCHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCC
RKILVNYAKRQVGNKIYGGQSSHLPLKLNMAGVIPPIFASSIILFPATIAGWFTAGNSTN
HHHHHHHHHHHHCCCCCCCCCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCC
PVARFVKDLASTLSPGQPVYILLYAAAIIFFCFFYTALVYNSREVADNLKKSGAFIPGIR
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCC
PGEQTTRYIDKILVRLTLAGAIYITLVCLLPEFLVLRWNVPFYFGGTSLLIIVVVTMDFM
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCEEECCHHHHHHHHHHHHHH
AQVQSYVMSQQYESLMKKANFKGNLTLR
HHHHHHHHHHHHHHHHHHCCCCCCCEEC
>Mature Secondary Structure 
ATAKPNVMAQAKNTAKYGDLRRRLVFLVLALLVYRIGAHIPVPGIDPDQLAQLFQRQSG
CCCCCCHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCC
GILGMFNLFSGGALSRFTVFALGIMPYISASIIMQLLTIVLPQLESLKKEGQAGQRKITQ
CEEEEHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
YTRYGTVVLATFQALGIAVALEAQPGLVLDPGLMFRATAVITLVTGTMFLMWLGEQITER
HHHHHHHHHHHHHHHCEEEEEECCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GLGNGISIIIFGGIAAGLPNAIGGLFELVRTGSMGIFSAILVVAIIGAVTFLVVFIERGQ
CCCCCCEEEEECCHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCC
RKILVNYAKRQVGNKIYGGQSSHLPLKLNMAGVIPPIFASSIILFPATIAGWFTAGNSTN
HHHHHHHHHHHHCCCCCCCCCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCC
PVARFVKDLASTLSPGQPVYILLYAAAIIFFCFFYTALVYNSREVADNLKKSGAFIPGIR
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCC
PGEQTTRYIDKILVRLTLAGAIYITLVCLLPEFLVLRWNVPFYFGGTSLLIIVVVTMDFM
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCEEECCHHHHHHHHHHHHHH
AQVQSYVMSQQYESLMKKANFKGNLTLR
HHHHHHHHHHHHHHHHHHCCCCCCCEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9322765; 10952301 [H]