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The map label for this gene is mlaC [H]

Identifier: 17547677

GI number: 17547677

Start: 3186526

End: 3187161

Strand: Reverse

Name: mlaC [H]

Synonym: RSc2958

Alternate gene names: 17547677

Gene position: 3187161-3186526 (Counterclockwise)

Preceding gene: 17547678

Following gene: 17547676

Centisome position: 85.76

GC content: 63.21

Gene sequence:

>636_bases
ATGTTCAAGAAACTCCTCCACTCCCTGTTTGCCGGCCTGACCTTCATGGCCGCCGTGGCTGCGGTGCCCGCACACGCGCA
GGAGGCCGATGCCCAGACCACCGTCAAGACGGCCGTGGACGACGTGCTCGCCACCATCAAGGGCGATTCGGATCTGCGCA
GCGGCAACATGCAAAAGGTCTTCCAGCTGGTCGATCAGAAGATCGTGCCGCGCGCGGATTTCAAGCGCACCACGCAAATT
GCGATGGGCCGCTTCTGGAGCCAGGCCACGCCGGAGCAGCAGCAGCAGATCCAGGACGGCTTCAAGACGCTGCTGGTCCG
TACCTACGCGGGTGCGCTGGCGAACGTGCGTAACCAGACGGTGTCGTACAAGCCGTTCCGCGCCGCAGCGGACGACACCG
ACGTGGTGGTGCGCTCGACGGTCAACAACAACGGCGAGCCGGTGGCCCTGGACTACCGCATGGAAAAGTCCGCGAACGGC
TGGAAGGTCTATGACATCAACATCAGCGGGCTGTGGCTGTCGGAAACCTACAAGAACCAGTTTGCCGAGGTCATCAGCAA
GCGCGGCGGCGTGAGCGGTCTGGTGCAGTTCCTGGACGAGCGCAATGCCCAACTGGCGAAGGGGCCGGCAAAGTAA

Upstream 100 bases:

>100_bases
TCCCCGTCGAACTTGGCCGGGAGCGCCCGGTTCTAACCGCCAGCAAGATCGCAGCGGCGATGCTGTTTGTGGACCAGAAA
TCACAATAGAAGGACGCGAT

Downstream 100 bases:

>100_bases
GCCGATCTCCGGTAGAATCCACACAGCGGTCGATTGCGGCCGCTGTTTCTTTTTCTGCTCCCGCCCATGCTGACCCTGTC
CGGCCCGCTGACTCACCGCG

Product: signal peptide protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 211; Mature: 211

Protein sequence:

>211_residues
MFKKLLHSLFAGLTFMAAVAAVPAHAQEADAQTTVKTAVDDVLATIKGDSDLRSGNMQKVFQLVDQKIVPRADFKRTTQI
AMGRFWSQATPEQQQQIQDGFKTLLVRTYAGALANVRNQTVSYKPFRAAADDTDVVVRSTVNNNGEPVALDYRMEKSANG
WKVYDINISGLWLSETYKNQFAEVISKRGGVSGLVQFLDERNAQLAKGPAK

Sequences:

>Translated_211_residues
MFKKLLHSLFAGLTFMAAVAAVPAHAQEADAQTTVKTAVDDVLATIKGDSDLRSGNMQKVFQLVDQKIVPRADFKRTTQI
AMGRFWSQATPEQQQQIQDGFKTLLVRTYAGALANVRNQTVSYKPFRAAADDTDVVVRSTVNNNGEPVALDYRMEKSANG
WKVYDINISGLWLSETYKNQFAEVISKRGGVSGLVQFLDERNAQLAKGPAK
>Mature_211_residues
MFKKLLHSLFAGLTFMAAVAAVPAHAQEADAQTTVKTAVDDVLATIKGDSDLRSGNMQKVFQLVDQKIVPRADFKRTTQI
AMGRFWSQATPEQQQQIQDGFKTLLVRTYAGALANVRNQTVSYKPFRAAADDTDVVVRSTVNNNGEPVALDYRMEKSANG
WKVYDINISGLWLSETYKNQFAEVISKRGGVSGLVQFLDERNAQLAKGPAK

Specific function: Actively prevents phospholipid accumulation at the cell surface. Probably maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane. May transfer phospholipid across the peripl

COG id: COG2854

COG function: function code Q; ABC-type transport system involved in resistance to organic solvents, auxiliary component

Gene ontology:

Cell location: Periplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mlaC/ttg2D family [H]

Homologues:

Organism=Escherichia coli, GI1789583, Length=198, Percent_Identity=25.7575757575758, Blast_Score=71, Evalue=6e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023094
- InterPro:   IPR008869 [H]

Pfam domain/function: PF05494 Tol_Tol_Ttg2 [H]

EC number: NA

Molecular weight: Translated: 23273; Mature: 23273

Theoretical pI: Translated: 9.96; Mature: 9.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFKKLLHSLFAGLTFMAAVAAVPAHAQEADAQTTVKTAVDDVLATIKGDSDLRSGNMQKV
CHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHH
FQLVDQKIVPRADFKRTTQIAMGRFWSQATPEQQQQIQDGFKTLLVRTYAGALANVRNQT
HHHHHHHCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
VSYKPFRAAADDTDVVVRSTVNNNGEPVALDYRMEKSANGWKVYDINISGLWLSETYKNQ
CCCCCCCCCCCCCCEEEEECCCCCCCEEEEEEEECCCCCCCEEEEEEECEEEHHHHHHHH
FAEVISKRGGVSGLVQFLDERNAQLAKGPAK
HHHHHHHCCCHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MFKKLLHSLFAGLTFMAAVAAVPAHAQEADAQTTVKTAVDDVLATIKGDSDLRSGNMQKV
CHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHH
FQLVDQKIVPRADFKRTTQIAMGRFWSQATPEQQQQIQDGFKTLLVRTYAGALANVRNQT
HHHHHHHCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
VSYKPFRAAADDTDVVVRSTVNNNGEPVALDYRMEKSANGWKVYDINISGLWLSETYKNQ
CCCCCCCCCCCCCCEEEEECCCCCCCEEEEEEEECCCCCCCEEEEEEECEEEHHHHHHHH
FAEVISKRGGVSGLVQFLDERNAQLAKGPAK
HHHHHHHCCCHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]