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The map label for this gene is trpG [H]

Identifier: 17547601

GI number: 17547601

Start: 3110493

End: 3111062

Strand: Direct

Name: trpG [H]

Synonym: RSc2882

Alternate gene names: 17547601

Gene position: 3110493-3111062 (Clockwise)

Preceding gene: 17547600

Following gene: 17547602

Centisome position: 83.7

GC content: 64.56

Gene sequence:

>570_bases
ATGCTGCTGATGATCGACAACTACGACTCCTTCACCTACAACATCGTCCAGTACTTCGGCGAGCTCGGCCAGGACGTGCG
CACGGTTCGCAACGACGAGATCACGATCGAGGCGATCGAGCAATTGAACCCGGAGCGCATCTGCCTCTCGCCCGGGCCGT
GCACGCCCAAGGAAGCCGGCATTTGCCTACCGGTGCTGGAGCACTTTGCGGGGCGCATTCCCATCCTGGGCGTGTGCCTG
GGGCATCAGGCCATCGGCGATGCGTTCGGTGGCCGCGTGATCCGCGCGCAGAAGGTGATGCACGGCAAGGTCAGCACCAT
CGAGAACACCGGCGCCGGCGTGTTCGCCAACCTGCCGCGCCATTTCAAGGTGACGCGCTATCACTCGCTGGCGATCGAGC
GCGAGACGCTGCCCGACTGCCTGGAGGTGACCGCCTGGACCGAAGACGGCGAGATCATGGGCGTGCGCCACAAGACGCTG
CCGGTCGAAGGCGTGCAGTTCCACCCCGAATCGATCCTGTCGGAGCACGGCCACGCCCTGCTGGCCAATTTCCTGAAGGA
ACGCGCCTGA

Upstream 100 bases:

>100_bases
AATGGCGCGAGACCGAACACAAGGCGCGCGCCGTGCTGCGCGCCGCCGAGCAGGTCCAGGACGGCCTGGACGCCGATTTC
TGACAGGCAAGGAGCCCAAC

Downstream 100 bases:

>100_bases
TGCGCGCCCGCGCGTGCGTGGCGGCGGCGCTGGCCGTGCTGGCCGCGCCGATCGCGCTGGCCGGCACGCTGGAGGCCTGC
CGTACCGCCCCGCCCGAAGC

Product: anthranilate synthase component II

Products: NA

Alternate protein names: Anthranilate synthase component II; Glutamine amido-transferase [H]

Number of amino acids: Translated: 189; Mature: 189

Protein sequence:

>189_residues
MLLMIDNYDSFTYNIVQYFGELGQDVRTVRNDEITIEAIEQLNPERICLSPGPCTPKEAGICLPVLEHFAGRIPILGVCL
GHQAIGDAFGGRVIRAQKVMHGKVSTIENTGAGVFANLPRHFKVTRYHSLAIERETLPDCLEVTAWTEDGEIMGVRHKTL
PVEGVQFHPESILSEHGHALLANFLKERA

Sequences:

>Translated_189_residues
MLLMIDNYDSFTYNIVQYFGELGQDVRTVRNDEITIEAIEQLNPERICLSPGPCTPKEAGICLPVLEHFAGRIPILGVCL
GHQAIGDAFGGRVIRAQKVMHGKVSTIENTGAGVFANLPRHFKVTRYHSLAIERETLPDCLEVTAWTEDGEIMGVRHKTL
PVEGVQFHPESILSEHGHALLANFLKERA
>Mature_189_residues
MLLMIDNYDSFTYNIVQYFGELGQDVRTVRNDEITIEAIEQLNPERICLSPGPCTPKEAGICLPVLEHFAGRIPILGVCL
GHQAIGDAFGGRVIRAQKVMHGKVSTIENTGAGVFANLPRHFKVTRYHSLAIERETLPDCLEVTAWTEDGEIMGVRHKTL
PVEGVQFHPESILSEHGHALLANFLKERA

Specific function: Catalyzes The Biosynthesis Of 4-Amino-4-Deoxychorismate (Adc) From Chorismate And Glutamine. [C]

COG id: COG0512

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component II

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1789760, Length=185, Percent_Identity=63.7837837837838, Blast_Score=257, Evalue=4e-70,
Organism=Escherichia coli, GI1787517, Length=188, Percent_Identity=43.0851063829787, Blast_Score=140, Evalue=4e-35,
Organism=Escherichia coli, GI1786215, Length=162, Percent_Identity=27.1604938271605, Blast_Score=65, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6322638, Length=185, Percent_Identity=50.8108108108108, Blast_Score=202, Evalue=3e-53,
Organism=Saccharomyces cerevisiae, GI6324361, Length=212, Percent_Identity=37.2641509433962, Blast_Score=98, Evalue=7e-22,
Organism=Drosophila melanogaster, GI281365319, Length=119, Percent_Identity=32.7731092436975, Blast_Score=73, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006220
- InterPro:   IPR011702
- InterPro:   IPR017926
- InterPro:   IPR000991
- InterPro:   IPR006221 [H]

Pfam domain/function: PF00117 GATase [H]

EC number: =4.1.3.27 [H]

Molecular weight: Translated: 20986; Mature: 20986

Theoretical pI: Translated: 6.02; Mature: 6.02

Prosite motif: PS00442 GATASE_TYPE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLMIDNYDSFTYNIVQYFGELGQDVRTVRNDEITIEAIEQLNPERICLSPGPCTPKEAG
CEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHCCCCEEEECCCCCCCCCCC
ICLPVLEHFAGRIPILGVCLGHQAIGDAFGGRVIRAQKVMHGKVSTIENTGAGVFANLPR
CCHHHHHHHCCCCCEEEEECCHHHHHHHHCCCEEEHHHHHHCCHHEECCCCCCEEECCCC
HFKVTRYHSLAIERETLPDCLEVTAWTEDGEIMGVRHKTLPVEGVQFHPESILSEHGHAL
CEEEEEHHHHEECHHCCHHHHHHEEECCCCCEEEEEECCCCCCCCEECHHHHHHHCCHHH
LANFLKERA
HHHHHHHCC
>Mature Secondary Structure
MLLMIDNYDSFTYNIVQYFGELGQDVRTVRNDEITIEAIEQLNPERICLSPGPCTPKEAG
CEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHCCCCEEEECCCCCCCCCCC
ICLPVLEHFAGRIPILGVCLGHQAIGDAFGGRVIRAQKVMHGKVSTIENTGAGVFANLPR
CCHHHHHHHCCCCCEEEEECCHHHHHHHHCCCEEEHHHHHHCCHHEECCCCCCEEECCCC
HFKVTRYHSLAIERETLPDCLEVTAWTEDGEIMGVRHKTLPVEGVQFHPESILSEHGHAL
CEEEEEHHHHEECHHCCHHHHHHEEECCCCCEEEEEECCCCCCCCEECHHHHHHHCCHHH
LANFLKERA
HHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 6599977 [H]