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The map label for this gene is mraY [H]

Identifier: 17547566

GI number: 17547566

Start: 3063381

End: 3064550

Strand: Reverse

Name: mraY [H]

Synonym: RSc2847

Alternate gene names: 17547566

Gene position: 3064550-3063381 (Counterclockwise)

Preceding gene: 17547567

Following gene: 161621732

Centisome position: 82.46

GC content: 64.53

Gene sequence:

>1170_bases
ATGTTATTGGCATTGGCGCAGTGGCTGCAGAACGACTTCGGCTTCCTGCGCGTCTTCAACTATCTGACGTTCCGGGCCGT
GATGGCATCCCTCACGGCGCTGGTGATCGGCCTCGGCTTCGGGCCATGGGTGATCCGTCGCCTGACCGAGCTCAAGGTCG
GCCAGGCCGTGCGCAGCTATGGCCCGCAGACCCACCTAGTCAAGGCCGGCACACCCACCATGGGCGGCGTGCTGGTGCTG
ATCGGCATTGCCGTCTCCACGCTGCTGTGGTGCGACTGGGGCAACCGCTTCATCTGGATCGTGCTGCTGGTCACACTCGG
CTATGGGACGATCGGCTGGGTGGACGACTACCGCAAGGTGGTCCACCGCGACCCGAAGGGCATGTCCTCGCGCGAGAAGT
TCTTCTGGCAGACGGTGATCGGCCTGTTCGCCGCCGCCTATCTGGCGTTCTCCGTGTCCGAGACCAGCAACATGCGCGTG
CTGGAGCTGTTCCTGGACTGGGTGCGCAGTGGCCTGTCGCTGAGCCTGCCAGCCAAGTCGCACCTGATCGTGCCGTTCTT
CAAGGAGCTCAGTTATCCGCTGGGCGTGTTCGGCTTCATCGTGCTGACCTACCTCGTCATCGTCGGCTCCAGCAACGCGG
TGAACCTGACCGACGGCCTGGACGGCCTGGTCATCATGCCGGTGGTGCTGGTGGGCAGCGCACTGGGCATCTTCGCCTAT
GTGATGGGCAGCGCGGTCTACAGCAAGTACCTGCTGTTCCCGCACATCCCGGGCGCGGGCGAACTGCTGATTTTCTGCTC
GGCGATGGCCGGTGCCGGCCTGGCCTTCCTGTGGTTCAACGCCCATCCGGCCCAGGTGTTCATGGGCGACGTCGGCGCGC
TGGCGCTGGGCGGGGCGCTCGGCACCGTCGCGGTGATCGTGCGGCAGGAGATCGTGCTGTTCATCATGGGCGGCGTGTTC
GTGGCCGAAACCATTTCGGTGATGCTGCAGGTGACCTGGTTCAAGTTCACCAAGCGGCGCTACGGCGAGGGCCGGCGGCT
GTTCCGCATGGCCCCGCTGCACCACCATTTCGAGCTGTCCGGCTGGAAGGAAACGCAGGTCGTCGTGCGTTTCTGGATCA
TCACCATGATGCTGGTGCTGATCGGCCTGTCGACGCTGAAGCTGCGGTGA

Upstream 100 bases:

>100_bases
GCATTGTCGATGCGCTGGTCTTGAAAGACCCGGCAGCCGACTCGCAAGGGGCGCCGGGGACGACGCACACACAACAGACG
CACTAAGGGATGTAGCACCC

Downstream 100 bases:

>100_bases
GGATGCGGACATGACCGAACCGATCCGCGCTCCCGAAGACACGCTGCCGACGCCGCCGGCCGCCGGGGACGCGCTCATCG
CCGGCGCCATTGCTGCGACC

Product: phospho-N-acetylmuramoyl-pentapeptide- transferase

Products: NA

Alternate protein names: UDP-MurNAc-pentapeptide phosphotransferase [H]

Number of amino acids: Translated: 389; Mature: 389

Protein sequence:

>389_residues
MLLALAQWLQNDFGFLRVFNYLTFRAVMASLTALVIGLGFGPWVIRRLTELKVGQAVRSYGPQTHLVKAGTPTMGGVLVL
IGIAVSTLLWCDWGNRFIWIVLLVTLGYGTIGWVDDYRKVVHRDPKGMSSREKFFWQTVIGLFAAAYLAFSVSETSNMRV
LELFLDWVRSGLSLSLPAKSHLIVPFFKELSYPLGVFGFIVLTYLVIVGSSNAVNLTDGLDGLVIMPVVLVGSALGIFAY
VMGSAVYSKYLLFPHIPGAGELLIFCSAMAGAGLAFLWFNAHPAQVFMGDVGALALGGALGTVAVIVRQEIVLFIMGGVF
VAETISVMLQVTWFKFTKRRYGEGRRLFRMAPLHHHFELSGWKETQVVVRFWIITMMLVLIGLSTLKLR

Sequences:

>Translated_389_residues
MLLALAQWLQNDFGFLRVFNYLTFRAVMASLTALVIGLGFGPWVIRRLTELKVGQAVRSYGPQTHLVKAGTPTMGGVLVL
IGIAVSTLLWCDWGNRFIWIVLLVTLGYGTIGWVDDYRKVVHRDPKGMSSREKFFWQTVIGLFAAAYLAFSVSETSNMRV
LELFLDWVRSGLSLSLPAKSHLIVPFFKELSYPLGVFGFIVLTYLVIVGSSNAVNLTDGLDGLVIMPVVLVGSALGIFAY
VMGSAVYSKYLLFPHIPGAGELLIFCSAMAGAGLAFLWFNAHPAQVFMGDVGALALGGALGTVAVIVRQEIVLFIMGGVF
VAETISVMLQVTWFKFTKRRYGEGRRLFRMAPLHHHFELSGWKETQVVVRFWIITMMLVLIGLSTLKLR
>Mature_389_residues
MLLALAQWLQNDFGFLRVFNYLTFRAVMASLTALVIGLGFGPWVIRRLTELKVGQAVRSYGPQTHLVKAGTPTMGGVLVL
IGIAVSTLLWCDWGNRFIWIVLLVTLGYGTIGWVDDYRKVVHRDPKGMSSREKFFWQTVIGLFAAAYLAFSVSETSNMRV
LELFLDWVRSGLSLSLPAKSHLIVPFFKELSYPLGVFGFIVLTYLVIVGSSNAVNLTDGLDGLVIMPVVLVGSALGIFAY
VMGSAVYSKYLLFPHIPGAGELLIFCSAMAGAGLAFLWFNAHPAQVFMGDVGALALGGALGTVAVIVRQEIVLFIMGGVF
VAETISVMLQVTWFKFTKRRYGEGRRLFRMAPLHHHFELSGWKETQVVVRFWIITMMLVLIGLSTLKLR

Specific function: First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan [H]

COG id: COG0472

COG function: function code M; UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 4 family. MraY subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786275, Length=389, Percent_Identity=52.6992287917738, Blast_Score=369, Evalue=1e-103,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000715
- InterPro:   IPR003524
- InterPro:   IPR018480 [H]

Pfam domain/function: PF00953 Glycos_transf_4; PF10555 MraY_sig1 [H]

EC number: =2.7.8.13 [H]

Molecular weight: Translated: 43028; Mature: 43028

Theoretical pI: Translated: 10.15; Mature: 10.15

Prosite motif: PS01347 MRAY_1 ; PS01348 MRAY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCCHHHHHHHHHHHHHHHHHHCHHHHCCC
>Mature Secondary Structure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CCCHHHHHHHHHHHHHHHHHHCHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA