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The map label for this gene is tcp [H]

Identifier: 17547518

GI number: 17547518

Start: 3008339

End: 3009886

Strand: Direct

Name: tcp [H]

Synonym: RSc2799

Alternate gene names: 17547518

Gene position: 3008339-3009886 (Clockwise)

Preceding gene: 17547517

Following gene: 17547519

Centisome position: 80.95

GC content: 66.99

Gene sequence:

>1548_bases
ATGCGACAGTGGACACTCAAAGCAAAACTGCGCCTGGCGCTGGCCCTGATGTGGCTGGGCCTGATCGGCGTGGGCGTCTG
GAGTGCGATGGAAACCCGGGCCACCATGCTCGATGAGCGCAAGACGGGCCTGCAGAACCTGGTGGATGCCGCCGAGGGCA
TCGCCAAGCTGTATCACGCGAAGGCGCAGTCCGGCGCCATGGGCGAGGACGAGGCCAGGAAGACCGCCCTCGCGACGCTG
GCGTCGCTGCGCTATGGCACCACGGGCTATCTCTTCGTGGTGGATTCGCAGCTGATCCTGCAGATGCACCCGACGCTGGC
CGACATGGTCGGCAAGAGCACCGCCCAATTCAAAGACCCGACCGGCAAACCGCTCTACCCGGCCATCGTCAATGCCGCCA
AGGACAAAGGCTACGGCTTTGCCGAATACCAGGGCCGCCTGCCGGGCAGCGACACCGCCCTGCCCAAGATCGGCTACGTC
AAGCGCTTCGCCCCGTGGGACTGGAACATTTCCAGCGCCGTGTTCCTGCAGGAAGTGGAGACGGCCTACGTCCGCTCGCT
GATCGCCAACCTGATCGCCATCCTGGTGGTGGGCGGCGCGGTGACGCTGGCCATGTTCCTCATCATCCGCAATGTGCAGC
GCGGGCTGGGCGGTGAGCCGGCCTATGCCACCGAGATCGCCCGCCGAATCGCCGACGGCGACCTGGCGGTGCGCGTGCAG
ACCCGCCCGGATGACCGCAACAGCATGCTGTTCGCCATGGCCCGGATGCAGCAGCAACTGACCGGCACCATCGGCCATAT
CAAGACCTCCGCCGACTCGATCGCCAGCGCCACCCAGCAGATCGCCACCGGCAACGCCGACCTGTCGCAGCGCACGGAAG
AGCAGGCCAGCTCGCTGGAAGAAACGGCCTCCAGCATGGAAGAGCTGACCTCGATCGTGAAGCAGAACGCGGACAACGCG
CGCCAGGCGAGCACGCTGGCGGTCAACGCTTCGGACATCGCGGTCAAGGGCGGCGAGGTGGTGGGCCGCGTGGTCGATAC
CATGGCCGGCATCAACGACAGCAGCAAGAAGATCGCCGACATCATCGGCGTGATCGAGGGCATTGCATTCCAGACCAACA
TCCTGGCGCTGAACGCGGCGGTGGAAGCCGCCCGGGCCGGCGAGCAGGGTCGCGGCTTCGCGGTGGTGGCGGGCGAGGTG
CGCAGCCTGGCGCAGCGCTCGGCGGGGGCGGCCAAGGAGATCAAGGTGCTGATCTCGGACTCGGTCGGCCGGGTCGAGAA
CGGCACCACGCTGGTGGCCGAGGCCGGCACGGTGATCGACGAAGTGGTGGTGGCGGTCAAGCGCGTGACGGACATCATGG
GCGAGATCAGCGCGGCGTCGGACGAGCAGAGTTCGGGCATCGAGCAGGTCAACCAGGCCGTGAACCAGATGGACGAGGTG
ACGCAGCAGAACGCGGCACTGGTGGAAGAGGCCGCGGCCGCCGCGCTGTCGCTGGAAGAGCAGGCAACGTTGCTGCGCGA
CGCCGTGGCGTCGTTCCGTACGACCTGA

Upstream 100 bases:

>100_bases
CGTGCCCTTTGCGCCGCTCCATTAAAGAATCGCCGGGCCGCCGCCGTTACACCGGACGGGGAAACGCCCATGTGGGCAAG
ACAAGTGGAGAAAGCCCAAC

Downstream 100 bases:

>100_bases
CGCCGGCGGGCCGCCCGCTCCCAACGAGGGGAGGGGCGGTCCGCCGTTTTCGGGCACGCCGCATGGTGCTATGCTGCGCG
CCAGAGGAACCTCATCATAA

Product: methyl-accepting chemotaxis transmembrane protein

Products: NA

Alternate protein names: Citrate chemoreceptor protein [H]

Number of amino acids: Translated: 515; Mature: 515

Protein sequence:

>515_residues
MRQWTLKAKLRLALALMWLGLIGVGVWSAMETRATMLDERKTGLQNLVDAAEGIAKLYHAKAQSGAMGEDEARKTALATL
ASLRYGTTGYLFVVDSQLILQMHPTLADMVGKSTAQFKDPTGKPLYPAIVNAAKDKGYGFAEYQGRLPGSDTALPKIGYV
KRFAPWDWNISSAVFLQEVETAYVRSLIANLIAILVVGGAVTLAMFLIIRNVQRGLGGEPAYATEIARRIADGDLAVRVQ
TRPDDRNSMLFAMARMQQQLTGTIGHIKTSADSIASATQQIATGNADLSQRTEEQASSLEETASSMEELTSIVKQNADNA
RQASTLAVNASDIAVKGGEVVGRVVDTMAGINDSSKKIADIIGVIEGIAFQTNILALNAAVEAARAGEQGRGFAVVAGEV
RSLAQRSAGAAKEIKVLISDSVGRVENGTTLVAEAGTVIDEVVVAVKRVTDIMGEISAASDEQSSGIEQVNQAVNQMDEV
TQQNAALVEEAAAAALSLEEQATLLRDAVASFRTT

Sequences:

>Translated_515_residues
MRQWTLKAKLRLALALMWLGLIGVGVWSAMETRATMLDERKTGLQNLVDAAEGIAKLYHAKAQSGAMGEDEARKTALATL
ASLRYGTTGYLFVVDSQLILQMHPTLADMVGKSTAQFKDPTGKPLYPAIVNAAKDKGYGFAEYQGRLPGSDTALPKIGYV
KRFAPWDWNISSAVFLQEVETAYVRSLIANLIAILVVGGAVTLAMFLIIRNVQRGLGGEPAYATEIARRIADGDLAVRVQ
TRPDDRNSMLFAMARMQQQLTGTIGHIKTSADSIASATQQIATGNADLSQRTEEQASSLEETASSMEELTSIVKQNADNA
RQASTLAVNASDIAVKGGEVVGRVVDTMAGINDSSKKIADIIGVIEGIAFQTNILALNAAVEAARAGEQGRGFAVVAGEV
RSLAQRSAGAAKEIKVLISDSVGRVENGTTLVAEAGTVIDEVVVAVKRVTDIMGEISAASDEQSSGIEQVNQAVNQMDEV
TQQNAALVEEAAAAALSLEEQATLLRDAVASFRTT
>Mature_515_residues
MRQWTLKAKLRLALALMWLGLIGVGVWSAMETRATMLDERKTGLQNLVDAAEGIAKLYHAKAQSGAMGEDEARKTALATL
ASLRYGTTGYLFVVDSQLILQMHPTLADMVGKSTAQFKDPTGKPLYPAIVNAAKDKGYGFAEYQGRLPGSDTALPKIGYV
KRFAPWDWNISSAVFLQEVETAYVRSLIANLIAILVVGGAVTLAMFLIIRNVQRGLGGEPAYATEIARRIADGDLAVRVQ
TRPDDRNSMLFAMARMQQQLTGTIGHIKTSADSIASATQQIATGNADLSQRTEEQASSLEETASSMEELTSIVKQNADNA
RQASTLAVNASDIAVKGGEVVGRVVDTMAGINDSSKKIADIIGVIEGIAFQTNILALNAAVEAARAGEQGRGFAVVAGEV
RSLAQRSAGAAKEIKVLISDSVGRVENGTTLVAEAGTVIDEVVVAVKRVTDIMGEISAASDEQSSGIEQVNQAVNQMDEV
TQQNAALVEEAAAAALSLEEQATLLRDAVASFRTT

Specific function: Acts as a receptor for citrate and mediates taxis away from phenol. Also mediates an attractant response to metal-citrate complexes [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1788195, Length=306, Percent_Identity=62.0915032679739, Blast_Score=313, Evalue=2e-86,
Organism=Escherichia coli, GI2367378, Length=326, Percent_Identity=59.5092024539877, Blast_Score=301, Evalue=5e-83,
Organism=Escherichia coli, GI1787690, Length=343, Percent_Identity=53.6443148688047, Blast_Score=298, Evalue=4e-82,
Organism=Escherichia coli, GI1788194, Length=284, Percent_Identity=58.0985915492958, Blast_Score=283, Evalue=2e-77,
Organism=Escherichia coli, GI1789453, Length=284, Percent_Identity=40.1408450704225, Blast_Score=201, Evalue=9e-53,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR003122
- InterPro:   IPR004091
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal; PF02203 TarH [H]

EC number: NA

Molecular weight: Translated: 54630; Mature: 54630

Theoretical pI: Translated: 4.89; Mature: 4.89

Prosite motif: PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRQWTLKAKLRLALALMWLGLIGVGVWSAMETRATMLDERKTGLQNLVDAAEGIAKLYHA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KAQSGAMGEDEARKTALATLASLRYGTTGYLFVVDSQLILQMHPTLADMVGKSTAQFKDP
HHCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEECCHHHHHHCHHHHHHHCCCHHCCCCC
TGKPLYPAIVNAAKDKGYGFAEYQGRLPGSDTALPKIGYVKRFAPWDWNISSAVFLQEVE
CCCCCHHHHHHHHHCCCCCCHHHCCCCCCCCCCCCCCCHHHHCCCCCCCCHHHHHHHHHH
TAYVRSLIANLIAILVVGGAVTLAMFLIIRNVQRGLGGEPAYATEIARRIADGDLAVRVQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCEEEEEE
TRPDDRNSMLFAMARMQQQLTGTIGHIKTSADSIASATQQIATGNADLSQRTEEQASSLE
CCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
ETASSMEELTSIVKQNADNARQASTLAVNASDIAVKGGEVVGRVVDTMAGINDSSKKIAD
HHHHHHHHHHHHHHCCCCCHHHHHEEEECCCHHEECCHHHHHHHHHHHHCCCCCHHHHHH
IIGVIEGIAFQTNILALNAAVEAARAGEQGRGFAVVAGEVRSLAQRSAGAAKEIKVLISD
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHCCCCHHHHHHHHHC
SVGRVENGTTLVAEAGTVIDEVVVAVKRVTDIMGEISAASDEQSSGIEQVNQAVNQMDEV
CCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHCCHHHHHHHHHHHHHH
TQQNAALVEEAAAAALSLEEQATLLRDAVASFRTT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MRQWTLKAKLRLALALMWLGLIGVGVWSAMETRATMLDERKTGLQNLVDAAEGIAKLYHA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KAQSGAMGEDEARKTALATLASLRYGTTGYLFVVDSQLILQMHPTLADMVGKSTAQFKDP
HHCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEECCHHHHHHCHHHHHHHCCCHHCCCCC
TGKPLYPAIVNAAKDKGYGFAEYQGRLPGSDTALPKIGYVKRFAPWDWNISSAVFLQEVE
CCCCCHHHHHHHHHCCCCCCHHHCCCCCCCCCCCCCCCHHHHCCCCCCCCHHHHHHHHHH
TAYVRSLIANLIAILVVGGAVTLAMFLIIRNVQRGLGGEPAYATEIARRIADGDLAVRVQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCEEEEEE
TRPDDRNSMLFAMARMQQQLTGTIGHIKTSADSIASATQQIATGNADLSQRTEEQASSLE
CCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
ETASSMEELTSIVKQNADNARQASTLAVNASDIAVKGGEVVGRVVDTMAGINDSSKKIAD
HHHHHHHHHHHHHHCCCCCHHHHHEEEECCCHHEECCHHHHHHHHHHHHCCCCCHHHHHH
IIGVIEGIAFQTNILALNAAVEAARAGEQGRGFAVVAGEVRSLAQRSAGAAKEIKVLISD
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHCCCCHHHHHHHHHC
SVGRVENGTTLVAEAGTVIDEVVVAVKRVTDIMGEISAASDEQSSGIEQVNQAVNQMDEV
CCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHCCHHHHHHHHHHHHHH
TQQNAALVEEAAAAALSLEEQATLLRDAVASFRTT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8419927; 11677609 [H]