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The map label for this gene is dapB

Identifier: 17547464

GI number: 17547464

Start: 2956139

End: 2956930

Strand: Reverse

Name: dapB

Synonym: RSc2745

Alternate gene names: 17547464

Gene position: 2956930-2956139 (Counterclockwise)

Preceding gene: 17547465

Following gene: 17547463

Centisome position: 79.56

GC content: 67.42

Gene sequence:

>792_bases
ATGAAAATCGCGATTGCAGGGGCCTCGGGCCGCATGGGCCAGATGTTGATCGACACCGTTCTGCGCACGCCCGGCGTGAC
GCTGGCTGCCGCGCTGGACCGCGCGGGCAGCGATGCCGTGGGCCAGGATGCCGGCGCCAGGCTGGGCAAGGCCACGGGCG
TGATCGTGACCGATGACCTGCGCACCGGCCTGTCCCAGGCCGATGTGCTGATCGACTTCACCCGTCCGGAGGCGACGCTG
GCGCACCTGGAGATCGCGCGCGAACTCGGTGTCGGCGTGGTCATCGGCACCACCGGCTTCACCGCCGAGCAGAAAGCGAG
CTTCAAGGACTATGGCGCCACCATCGGCGTGGTGTGGGCGCCGAACATGAGCGTGGGTGTGAATGCCACCTTCAAGCTGA
TCGAAGTGGCCGCCAAGATTCTGGCGCAGGGCTATGACGTCGAGATCGTCGAGGCCCACCACAAGCACAAGATCGACGCG
CCGTCCGGCACCGCGCTGAAGATGGGCGAGATCGTGGCCGAGGCGCAGGGTACGACGCTGGCCGAGCGCGCGGTTTACGC
GCGCGAGGGTGAGACCGGCCCGCGCATGAACGGCACCATCGGCTTTGCCACCGTGCGTGGCGGCGATATTGTCGGCGACC
ACACCGTGCTGTTCGTCGGCGAGGGCGAGCGCATCGAGATCACGCACCGCTCCAATTCCCGCCAGTCGTACGCCGAGGGC
GCGGTACGCGCCGCCTGCTTCCTGGCGGGCAAGAAAGGGCTGTTCGACATGAACGACGTGCTCGGCCTGTAA

Upstream 100 bases:

>100_bases
CAGCGCGGCCTGCGGGCAGCATGACCACCAGCGAGCGGCGGACCGGTTCCGCCGCTCGTCCGTTGTACCGACCGTTTTTT
CTTTTCTCGTTCCGATCCAC

Downstream 100 bases:

>100_bases
GCCGGGCGAGTGCGCCGGCCGGGCGGTCCGTCGCCTGTCCGCGCGGTGCGCCATGCTCCGGTCCGGGGGCATGGCGACGG
TATAATCGGGCCTTTTCCGT

Product: dihydrodipicolinate reductase

Products: NA

Alternate protein names: DHPR

Number of amino acids: Translated: 263; Mature: 263

Protein sequence:

>263_residues
MKIAIAGASGRMGQMLIDTVLRTPGVTLAAALDRAGSDAVGQDAGARLGKATGVIVTDDLRTGLSQADVLIDFTRPEATL
AHLEIARELGVGVVIGTTGFTAEQKASFKDYGATIGVVWAPNMSVGVNATFKLIEVAAKILAQGYDVEIVEAHHKHKIDA
PSGTALKMGEIVAEAQGTTLAERAVYAREGETGPRMNGTIGFATVRGGDIVGDHTVLFVGEGERIEITHRSNSRQSYAEG
AVRAACFLAGKKGLFDMNDVLGL

Sequences:

>Translated_263_residues
MKIAIAGASGRMGQMLIDTVLRTPGVTLAAALDRAGSDAVGQDAGARLGKATGVIVTDDLRTGLSQADVLIDFTRPEATL
AHLEIARELGVGVVIGTTGFTAEQKASFKDYGATIGVVWAPNMSVGVNATFKLIEVAAKILAQGYDVEIVEAHHKHKIDA
PSGTALKMGEIVAEAQGTTLAERAVYAREGETGPRMNGTIGFATVRGGDIVGDHTVLFVGEGERIEITHRSNSRQSYAEG
AVRAACFLAGKKGLFDMNDVLGL
>Mature_263_residues
MKIAIAGASGRMGQMLIDTVLRTPGVTLAAALDRAGSDAVGQDAGARLGKATGVIVTDDLRTGLSQADVLIDFTRPEATL
AHLEIARELGVGVVIGTTGFTAEQKASFKDYGATIGVVWAPNMSVGVNATFKLIEVAAKILAQGYDVEIVEAHHKHKIDA
PSGTALKMGEIVAEAQGTTLAERAVYAREGETGPRMNGTIGFATVRGGDIVGDHTVLFVGEGERIEITHRSNSRQSYAEG
AVRAACFLAGKKGLFDMNDVLGL

Specific function: Biosynthesis of diaminopimelate and lysine from aspartate semialdehyde; second step. [C]

COG id: COG0289

COG function: function code E; Dihydrodipicolinate reductase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dihydrodipicolinate reductase family

Homologues:

Organism=Escherichia coli, GI1786214, Length=265, Percent_Identity=55.8490566037736, Blast_Score=267, Evalue=6e-73,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DAPB_RALSO (Q8XVT2)

Other databases:

- EMBL:   AL646052
- RefSeq:   NP_520866.1
- ProteinModelPortal:   Q8XVT2
- SMR:   Q8XVT2
- GeneID:   1221592
- GenomeReviews:   AL646052_GR
- KEGG:   rso:RSc2745
- NMPDR:   fig|267608.1.peg.2745
- HOGENOM:   HBG594002
- OMA:   GRMGKTL
- ProtClustDB:   PRK00048
- BioCyc:   RSOL267608:RSC2745-MONOMER
- BRENDA:   1.3.1.26
- GO:   GO:0005737
- GO:   GO:0005488
- HAMAP:   MF_00102
- InterPro:   IPR022663
- InterPro:   IPR000846
- InterPro:   IPR022664
- InterPro:   IPR011770
- InterPro:   IPR016040
- Gene3D:   G3DSA:3.40.50.720
- PANTHER:   PTHR20836
- TIGRFAMs:   TIGR00036

Pfam domain/function: PF05173 DapB_C; PF01113 DapB_N

EC number: =1.3.1.26

Molecular weight: Translated: 27420; Mature: 27420

Theoretical pI: Translated: 5.96; Mature: 5.96

Prosite motif: PS01298 DAPB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIAIAGASGRMGQMLIDTVLRTPGVTLAAALDRAGSDAVGQDAGARLGKATGVIVTDDL
CEEEEECCCCCCHHHHHHHHHHCCCCEEEHHHCCCCCCCCCCCCCCCCCCCCEEEEECHH
RTGLSQADVLIDFTRPEATLAHLEIARELGVGVVIGTTGFTAEQKASFKDYGATIGVVWA
HCCCCCCEEEEEECCCCHHHHHHHHHHHCCCEEEEECCCCCCHHHCCHHHCCCEEEEEEC
PNMSVGVNATFKLIEVAAKILAQGYDVEIVEAHHKHKIDAPSGTALKMGEIVAEAQGTTL
CCCCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCEEEHHHHHHHCCCCHH
AERAVYAREGETGPRMNGTIGFATVRGGDIVGDHTVLFVGEGERIEITHRSNSRQSYAEG
HHHHHHHCCCCCCCCCCCEEEEEEEECCCEECCCEEEEEECCCEEEEEECCCCCHHHHHH
AVRAACFLAGKKGLFDMNDVLGL
HHHHHHEEECCCCCCCHHHHHCC
>Mature Secondary Structure
MKIAIAGASGRMGQMLIDTVLRTPGVTLAAALDRAGSDAVGQDAGARLGKATGVIVTDDL
CEEEEECCCCCCHHHHHHHHHHCCCCEEEHHHCCCCCCCCCCCCCCCCCCCCEEEEECHH
RTGLSQADVLIDFTRPEATLAHLEIARELGVGVVIGTTGFTAEQKASFKDYGATIGVVWA
HCCCCCCEEEEEECCCCHHHHHHHHHHHCCCEEEEECCCCCCHHHCCHHHCCCEEEEEEC
PNMSVGVNATFKLIEVAAKILAQGYDVEIVEAHHKHKIDAPSGTALKMGEIVAEAQGTTL
CCCCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCEEEHHHHHHHCCCCHH
AERAVYAREGETGPRMNGTIGFATVRGGDIVGDHTVLFVGEGERIEITHRSNSRQSYAEG
HHHHHHHCCCCCCCCCCCEEEEEEEECCCEECCCEEEEEECCCEEEEEECCCCCHHHHHH
AVRAACFLAGKKGLFDMNDVLGL
HHHHHHEEECCCCCCCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11823852