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The map label for this gene is pabB [H]

Identifier: 17547352

GI number: 17547352

Start: 2834813

End: 2836693

Strand: Reverse

Name: pabB [H]

Synonym: RSc2633

Alternate gene names: 17547352

Gene position: 2836693-2834813 (Counterclockwise)

Preceding gene: 17547353

Following gene: 17547342

Centisome position: 76.33

GC content: 72.51

Gene sequence:

>1881_bases
ATGCCGTTGCCAGATGCCGGCGCGCCGTTCGCGCTGCTGGACGATGCCACCTCGGCCGGTGCGCCATGCTCGCGCTGGTA
CACCGGCTATGCCGGCGAGATCGTCCGGCCGCCGGGCACGCTGGCGGGGCTGGACGATGCGCTGCGCGCGGCCTGGGCCG
ACGGTTTGCATGCGCTGGTCCTGGCCCCGTACGAATTCGGCCGGCCGCTGGTCGGCTTGTTATCGGCCATGCCGGCGTCC
GCTCGGTTGCCCGGCCACGACGGCTGTCTGCGCGTGCTGCTGTTCCGCTCGATGCAGGTGCTGTCGGCGGCCGAGGTCGA
TGCGCTGTTCGACGCGTGGCCCGAGGCCGGTAGCGCTGCCGGCCTGTTCGACTGTGCGGCCAGCGTCGACCATGACGCCT
ATGTTCACGCCATCGCCCGCATCCAGGACTGGATTGCCGCGGGCGATACCTACGAAGTCAATTACACGTACCGCCTGCGC
ATGACGGCGTTCGGCGCGCCGGCCGCGCTGTATCGCCGCCTGCGCGCGCGCCAGCCGGTGCCGTACGGGGCGCTGATCGG
ACTGCCGGAAGGCGGGGCAATCCTGTCGTGCTCGCCGGAACTGTTCTTCTCGCACCGCGCGGGCACCCTCGTCGCGCGGC
CGATGAAGGGCACCGCGCCCGCCAGCGGCGATCCGGAAGTCGACCAGGCGCGCGCCGCCGCGCTCGCCGCCGACGAGAAG
AACCGCGCCGAAAACCTGATGATTGTCGATCTGCTGCGCAATGACCTGGGCCGGCTCGCACGGCCGGGCTCGGTGCGCGT
GCCGACGCTGTTCGAGGTGACGCCGTACGGCAGCGTGCTGCAGATGACCTCCACGGTGCAGGCGGAGATTCCGCCCGAAA
CCGGCCTGGCCGACTGCCTCGCCGCGCTGTTTCCGTGCGGCTCCATCACGGGCGCGCCCAAGCGCCGGACCATGGAGATC
ATCGACGCGCTGGAGCCGCAGCCGCGCGGCTTCTACACCGGCGCGATCGGCTGGATCGACGCGCCCAGCGGCGATCGCGC
GATGGGCGACGCATGCTTTTCCGTGGCGATCCGCACGCTGGTGCTGGGGGCGCCCGGCACCGACGGCCTGCATTCGTGCG
AGCTCGGCATCGGCTCCGGCATCGTGCACGACAGCGCCGCCGACGAGGAATACGCCGAGTGCCGGCTGAAGGCGCGCTTC
GTCACCGCGCTCGATCCGGACCTGTCGCTGTTCGAGACGATGCGGGCGACGCGCGCCGAAGGCGTGCCCTTGCTGGAGCG
GCATCTGGCGCGGCTGGCGCATTCCGCCCGTGCGTTCGGCTTCGGTTTCGACAGGGATGCGCTGGTGCGCGAGGTGGCGC
GCGCGTGCGCCGCGCTGCCGGAGGCCGGCGCCCACCGCATGCGCCTGTCGCTGCGGCACAGCGGCGCATTCAGCGTCACG
GCGGCGCCGCTGCCGCCGCTGCATGCCAGCTGGAATGCGCCGGTGCGCCTGCGCGTCGCGCCGCAGGCACGCGAGGCCGC
GCACAGCCTGCCCCATCACAAGACCAGCCTGCGCGCCGCCTATGACGCAGCCTGGCAGGCCGCGGAGCGCGAGGGCGCGT
TCGATGCCGTGTTCTTCAATGCCGACGGTACCCTGGCCGAGGGCGGCCGCAGCACGGTGCTGGTCAAGCTGGAGGGGCGG
TGGTGGACGCCGCCGCTGTCGGCCGGCGTCCTGCCGGGCGTGATGCGCGCCGTGCTGCTGGAGGACGCGCGGCCGTGGCT
CGGCGCGCCCTTGCATGAACGCGTGCTGACCCGTGCCGACGTCGTCCGCGCCGAGGCCATCGCCGTCTGCAACGCGCTAC
GCGGCGTGGTGCCCGCGCATTTCGAGCCGCCCGTCGCTTAG

Upstream 100 bases:

>100_bases
GCTCGCGGCACAGTCCGCAGGAGCAGTCGTGGCTGGACAAGGTGAAGAACTTCTTCTCCAGCTGAGCGCCGCGCTTTTGC
TGTAACCGGGGGACATCGTC

Downstream 100 bases:

>100_bases
CTTCCACCGGGTCACGCCGGGCAGGTTGATCAGCTCGCGGTCGTGGCACACCATCAGCAGCGCGCGGCCCTCGGCCGCCA
GTTCGCCGACCAGCGCGAGC

Product: PARA-aminobenzoate synthetase component I protein

Products: NA

Alternate protein names: ADC synthase; Para-aminobenzoate synthase component I [H]

Number of amino acids: Translated: 626; Mature: 625

Protein sequence:

>626_residues
MPLPDAGAPFALLDDATSAGAPCSRWYTGYAGEIVRPPGTLAGLDDALRAAWADGLHALVLAPYEFGRPLVGLLSAMPAS
ARLPGHDGCLRVLLFRSMQVLSAAEVDALFDAWPEAGSAAGLFDCAASVDHDAYVHAIARIQDWIAAGDTYEVNYTYRLR
MTAFGAPAALYRRLRARQPVPYGALIGLPEGGAILSCSPELFFSHRAGTLVARPMKGTAPASGDPEVDQARAAALAADEK
NRAENLMIVDLLRNDLGRLARPGSVRVPTLFEVTPYGSVLQMTSTVQAEIPPETGLADCLAALFPCGSITGAPKRRTMEI
IDALEPQPRGFYTGAIGWIDAPSGDRAMGDACFSVAIRTLVLGAPGTDGLHSCELGIGSGIVHDSAADEEYAECRLKARF
VTALDPDLSLFETMRATRAEGVPLLERHLARLAHSARAFGFGFDRDALVREVARACAALPEAGAHRMRLSLRHSGAFSVT
AAPLPPLHASWNAPVRLRVAPQAREAAHSLPHHKTSLRAAYDAAWQAAEREGAFDAVFFNADGTLAEGGRSTVLVKLEGR
WWTPPLSAGVLPGVMRAVLLEDARPWLGAPLHERVLTRADVVRAEAIAVCNALRGVVPAHFEPPVA

Sequences:

>Translated_626_residues
MPLPDAGAPFALLDDATSAGAPCSRWYTGYAGEIVRPPGTLAGLDDALRAAWADGLHALVLAPYEFGRPLVGLLSAMPAS
ARLPGHDGCLRVLLFRSMQVLSAAEVDALFDAWPEAGSAAGLFDCAASVDHDAYVHAIARIQDWIAAGDTYEVNYTYRLR
MTAFGAPAALYRRLRARQPVPYGALIGLPEGGAILSCSPELFFSHRAGTLVARPMKGTAPASGDPEVDQARAAALAADEK
NRAENLMIVDLLRNDLGRLARPGSVRVPTLFEVTPYGSVLQMTSTVQAEIPPETGLADCLAALFPCGSITGAPKRRTMEI
IDALEPQPRGFYTGAIGWIDAPSGDRAMGDACFSVAIRTLVLGAPGTDGLHSCELGIGSGIVHDSAADEEYAECRLKARF
VTALDPDLSLFETMRATRAEGVPLLERHLARLAHSARAFGFGFDRDALVREVARACAALPEAGAHRMRLSLRHSGAFSVT
AAPLPPLHASWNAPVRLRVAPQAREAAHSLPHHKTSLRAAYDAAWQAAEREGAFDAVFFNADGTLAEGGRSTVLVKLEGR
WWTPPLSAGVLPGVMRAVLLEDARPWLGAPLHERVLTRADVVRAEAIAVCNALRGVVPAHFEPPVA
>Mature_625_residues
PLPDAGAPFALLDDATSAGAPCSRWYTGYAGEIVRPPGTLAGLDDALRAAWADGLHALVLAPYEFGRPLVGLLSAMPASA
RLPGHDGCLRVLLFRSMQVLSAAEVDALFDAWPEAGSAAGLFDCAASVDHDAYVHAIARIQDWIAAGDTYEVNYTYRLRM
TAFGAPAALYRRLRARQPVPYGALIGLPEGGAILSCSPELFFSHRAGTLVARPMKGTAPASGDPEVDQARAAALAADEKN
RAENLMIVDLLRNDLGRLARPGSVRVPTLFEVTPYGSVLQMTSTVQAEIPPETGLADCLAALFPCGSITGAPKRRTMEII
DALEPQPRGFYTGAIGWIDAPSGDRAMGDACFSVAIRTLVLGAPGTDGLHSCELGIGSGIVHDSAADEEYAECRLKARFV
TALDPDLSLFETMRATRAEGVPLLERHLARLAHSARAFGFGFDRDALVREVARACAALPEAGAHRMRLSLRHSGAFSVTA
APLPPLHASWNAPVRLRVAPQAREAAHSLPHHKTSLRAAYDAAWQAAEREGAFDAVFFNADGTLAEGGRSTVLVKLEGRW
WTPPLSAGVLPGVMRAVLLEDARPWLGAPLHERVLTRADVVRAEAIAVCNALRGVVPAHFEPPVA

Specific function: Catalyzes the biosynthesis of 4-amino-4-deoxychorismate (ADC) from chorismate and glutamine [H]

COG id: COG0147

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component I

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate synthase component I family [H]

Homologues:

Organism=Escherichia coli, GI1788114, Length=348, Percent_Identity=38.2183908045977, Blast_Score=192, Evalue=5e-50,
Organism=Escherichia coli, GI1787518, Length=285, Percent_Identity=29.1228070175439, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1786809, Length=228, Percent_Identity=25, Blast_Score=71, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6320935, Length=273, Percent_Identity=33.3333333333333, Blast_Score=130, Evalue=5e-31,
Organism=Saccharomyces cerevisiae, GI6324361, Length=310, Percent_Identity=31.2903225806452, Blast_Score=110, Evalue=6e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005801
- InterPro:   IPR019999
- InterPro:   IPR006805
- InterPro:   IPR015890
- InterPro:   IPR005802 [H]

Pfam domain/function: PF04715 Anth_synt_I_N; PF00425 Chorismate_bind [H]

EC number: =2.6.1.85 [H]

Molecular weight: Translated: 66542; Mature: 66410

Theoretical pI: Translated: 6.37; Mature: 6.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLPDAGAPFALLDDATSAGAPCSRWYTGYAGEIVRPPGTLAGLDDALRAAWADGLHALV
CCCCCCCCCEEEECCCCCCCCCHHHCCCCCCCCEECCCCCCCCHHHHHHHHHHCCCEEEE
LAPYEFGRPLVGLLSAMPASARLPGHDGCLRVLLFRSMQVLSAAEVDALFDAWPEAGSAA
ECCHHHCCHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
GLFDCAASVDHDAYVHAIARIQDWIAAGDTYEVNYTYRLRMTAFGAPAALYRRLRARQPV
CHHHHHHCCCCHHHHHHHHHHHHHHHCCCEEEEEEEEEEEEEECCCHHHHHHHHHHCCCC
PYGALIGLPEGGAILSCSPELFFSHRAGTLVARPMKGTAPASGDPEVDQARAAALAADEK
CCCEEEECCCCCEEEEECHHHHCCCCCCCEEECCCCCCCCCCCCCCHHHHHHHHHHCCCC
NRAENLMIVDLLRNDLGRLARPGSVRVPTLFEVTPYGSVLQMTSTVQAEIPPETGLADCL
CCCCCEEHHHHHHHHHHHHCCCCCCCCCEEEEECCCCHHHHHHHHHEECCCCCCCHHHHH
AALFPCGSITGAPKRRTMEIIDALEPQPRGFYTGAIGWIDAPSGDRAMGDACFSVAIRTL
HHHCCCCCCCCCCCHHHHHHHHHCCCCCCCEEECCEEEEECCCCCCHHHHHHHHHHHHHH
VLGAPGTDGLHSCELGIGSGIVHDSAADEEYAECRLKARFVTALDPDLSLFETMRATRAE
HCCCCCCCCCCEECCCCCCCCCCCCCCCHHHHHHHHHEEEEEECCCCHHHHHHHHHHHCC
GVPLLERHLARLAHSARAFGFGFDRDALVREVARACAALPEAGAHRMRLSLRHSGAFSVT
CCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCHHEEEEEECCCCEEEE
AAPLPPLHASWNAPVRLRVAPQAREAAHSLPHHKTSLRAAYDAAWQAAEREGAFDAVFFN
ECCCCCCCCCCCCCEEEEECCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCEEEEEEC
ADGTLAEGGRSTVLVKLEGRWWTPPLSAGVLPGVMRAVLLEDARPWLGAPLHERVLTRAD
CCCCCCCCCCEEEEEEECCEEECCCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHH
VVRAEAIAVCNALRGVVPAHFEPPVA
HHHHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure 
PLPDAGAPFALLDDATSAGAPCSRWYTGYAGEIVRPPGTLAGLDDALRAAWADGLHALV
CCCCCCCCEEEECCCCCCCCCHHHCCCCCCCCEECCCCCCCCHHHHHHHHHHCCCEEEE
LAPYEFGRPLVGLLSAMPASARLPGHDGCLRVLLFRSMQVLSAAEVDALFDAWPEAGSAA
ECCHHHCCHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
GLFDCAASVDHDAYVHAIARIQDWIAAGDTYEVNYTYRLRMTAFGAPAALYRRLRARQPV
CHHHHHHCCCCHHHHHHHHHHHHHHHCCCEEEEEEEEEEEEEECCCHHHHHHHHHHCCCC
PYGALIGLPEGGAILSCSPELFFSHRAGTLVARPMKGTAPASGDPEVDQARAAALAADEK
CCCEEEECCCCCEEEEECHHHHCCCCCCCEEECCCCCCCCCCCCCCHHHHHHHHHHCCCC
NRAENLMIVDLLRNDLGRLARPGSVRVPTLFEVTPYGSVLQMTSTVQAEIPPETGLADCL
CCCCCEEHHHHHHHHHHHHCCCCCCCCCEEEEECCCCHHHHHHHHHEECCCCCCCHHHHH
AALFPCGSITGAPKRRTMEIIDALEPQPRGFYTGAIGWIDAPSGDRAMGDACFSVAIRTL
HHHCCCCCCCCCCCHHHHHHHHHCCCCCCCEEECCEEEEECCCCCCHHHHHHHHHHHHHH
VLGAPGTDGLHSCELGIGSGIVHDSAADEEYAECRLKARFVTALDPDLSLFETMRATRAE
HCCCCCCCCCCEECCCCCCCCCCCCCCCHHHHHHHHHEEEEEECCCCHHHHHHHHHHHCC
GVPLLERHLARLAHSARAFGFGFDRDALVREVARACAALPEAGAHRMRLSLRHSGAFSVT
CCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCHHEEEEEECCCCEEEE
AAPLPPLHASWNAPVRLRVAPQAREAAHSLPHHKTSLRAAYDAAWQAAEREGAFDAVFFN
ECCCCCCCCCCCCCEEEEECCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCEEEEEEC
ADGTLAEGGRSTVLVKLEGRWWTPPLSAGVLPGVMRAVLLEDARPWLGAPLHERVLTRAD
CCCCCCCCCCEEEEEEECCEEECCCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHH
VVRAEAIAVCNALRGVVPAHFEPPVA
HHHHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3057324; 2251281 [H]