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The map label for this gene is sodB [H]

Identifier: 17547245

GI number: 17547245

Start: 2733298

End: 2733876

Strand: Reverse

Name: sodB [H]

Synonym: RSc2526

Alternate gene names: 17547245

Gene position: 2733876-2733298 (Counterclockwise)

Preceding gene: 17547246

Following gene: 17547241

Centisome position: 73.56

GC content: 63.56

Gene sequence:

>579_bases
ATGGCCCACACGCTCCCCCCGCTGCCGTACGCACTCGACGCCCTGGCGCCGCACATCTCCAAGGAAACCCTGGAGTTCCA
CTACGGCAAGCACCACCAGACCTACGTCACGAACCTGAACAACCTGATCCCGGGGACCGAGTTCGAGAACCTGAGCCTGG
AAGACATCGTCAAGAAGTCCTCGGGCGGCCTCTTCAACAACGCCGCGCAGGTGTGGAACCACACGTTCTACTGGAACGGC
CTGAAGCCCAACGGCGGCGGTGCTCCGGCCGGCGCGCTGGCTGACGCCATCAACGCCAAGTGGGGCAGCTTCGACAAGTT
CAAGGAAGAGTTCACCAAGGTCGCCATTGGCACCTTCGGCTCGGGCTGGGCCTGGCTGGTGAAGAAGGCGGACGGCTCGC
TGGACCTGGTGTCCACCTCCAATGCCGCCACGCCGCTGACGACGGACGCCAAGCCGCTGCTGACCTGCGACGTGTGGGAA
CACGCCTACTACATCGACTATCGCAACGCCCGTCCGAAGTACGTCGAGGCGTTCTGGAGCCTGGTCAACTGGGATTTCGT
CGCGAGCAACTTCGCCTGA

Upstream 100 bases:

>100_bases
TCGCGGGTATTCCGGTGATTCGGCGTGCGGTTTGCGCCGGTTTTGCATCTCTCCTACAATCTTCGCTCCCAACCCACGCA
ACCCACAGAAGGGAAGAACA

Downstream 100 bases:

>100_bases
GTCCCGGCTGTAGCGGGACCCTTCCGTTTGGAAAAACCAAGCGGGGTGTCGCGCTAAAGTCCAGAAAGCGCAATTAGAGC
AAGGCCCTCCATGAACGGAG

Product: superoxide dismutase [Fe] protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 192; Mature: 191

Protein sequence:

>192_residues
MAHTLPPLPYALDALAPHISKETLEFHYGKHHQTYVTNLNNLIPGTEFENLSLEDIVKKSSGGLFNNAAQVWNHTFYWNG
LKPNGGGAPAGALADAINAKWGSFDKFKEEFTKVAIGTFGSGWAWLVKKADGSLDLVSTSNAATPLTTDAKPLLTCDVWE
HAYYIDYRNARPKYVEAFWSLVNWDFVASNFA

Sequences:

>Translated_192_residues
MAHTLPPLPYALDALAPHISKETLEFHYGKHHQTYVTNLNNLIPGTEFENLSLEDIVKKSSGGLFNNAAQVWNHTFYWNG
LKPNGGGAPAGALADAINAKWGSFDKFKEEFTKVAIGTFGSGWAWLVKKADGSLDLVSTSNAATPLTTDAKPLLTCDVWE
HAYYIDYRNARPKYVEAFWSLVNWDFVASNFA
>Mature_191_residues
AHTLPPLPYALDALAPHISKETLEFHYGKHHQTYVTNLNNLIPGTEFENLSLEDIVKKSSGGLFNNAAQVWNHTFYWNGL
KPNGGGAPAGALADAINAKWGSFDKFKEEFTKVAIGTFGSGWAWLVKKADGSLDLVSTSNAATPLTTDAKPLLTCDVWEH
AYYIDYRNARPKYVEAFWSLVNWDFVASNFA

Specific function: Destroys radicals which are normally produced within the cells and which are toxic to biological systems [H]

COG id: COG0605

COG function: function code P; Superoxide dismutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron/manganese superoxide dismutase family [H]

Homologues:

Organism=Homo sapiens, GI67782307, Length=200, Percent_Identity=42.5, Blast_Score=162, Evalue=1e-40,
Organism=Homo sapiens, GI67782305, Length=200, Percent_Identity=42.5, Blast_Score=162, Evalue=1e-40,
Organism=Homo sapiens, GI67782309, Length=192, Percent_Identity=36.9791666666667, Blast_Score=124, Evalue=4e-29,
Organism=Escherichia coli, GI1787946, Length=192, Percent_Identity=72.3958333333333, Blast_Score=293, Evalue=4e-81,
Organism=Escherichia coli, GI1790342, Length=206, Percent_Identity=47.0873786407767, Blast_Score=177, Evalue=3e-46,
Organism=Caenorhabditis elegans, GI17506561, Length=200, Percent_Identity=38, Blast_Score=137, Evalue=3e-33,
Organism=Caenorhabditis elegans, GI17569479, Length=199, Percent_Identity=37.6884422110553, Blast_Score=134, Evalue=4e-32,
Organism=Saccharomyces cerevisiae, GI6321796, Length=209, Percent_Identity=37.799043062201, Blast_Score=125, Evalue=5e-30,
Organism=Drosophila melanogaster, GI17136812, Length=195, Percent_Identity=43.0769230769231, Blast_Score=152, Evalue=1e-37,

Paralogues:

None

Copy number: 2020 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 20 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). 900 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001189
- InterPro:   IPR019833
- InterPro:   IPR019832
- InterPro:   IPR019831 [H]

Pfam domain/function: PF02777 Sod_Fe_C; PF00081 Sod_Fe_N [H]

EC number: =1.15.1.1 [H]

Molecular weight: Translated: 21269; Mature: 21138

Theoretical pI: Translated: 6.39; Mature: 6.39

Prosite motif: PS00088 SOD_MN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
0.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAHTLPPLPYALDALAPHISKETLEFHYGKHHQTYVTNLNNLIPGTEFENLSLEDIVKKS
CCCCCCCCCHHHHHHHHHCCHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHH
SGGLFNNAAQVWNHTFYWNGLKPNGGGAPAGALADAINAKWGSFDKFKEEFTKVAIGTFG
CCCCCHHHHHHHCCEEEECCCCCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCC
SGWAWLVKKADGSLDLVSTSNAATPLTTDAKPLLTCDVWEHAYYIDYRNARPKYVEAFWS
CCEEEEEEECCCCEEEEECCCCCCCCCCCCCCEEEEEECCCEEEEEECCCCHHHHHHHHH
LVNWDFVASNFA
HHHHHHHHCCCC
>Mature Secondary Structure 
AHTLPPLPYALDALAPHISKETLEFHYGKHHQTYVTNLNNLIPGTEFENLSLEDIVKKS
CCCCCCCCHHHHHHHHHCCHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHH
SGGLFNNAAQVWNHTFYWNGLKPNGGGAPAGALADAINAKWGSFDKFKEEFTKVAIGTFG
CCCCCHHHHHHHCCEEEECCCCCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCC
SGWAWLVKKADGSLDLVSTSNAATPLTTDAKPLLTCDVWEHAYYIDYRNARPKYVEAFWS
CCEEEEEEECCCCEEEEECCCCCCCCCCCCCCEEEEEECCCEEEEEECCCCHHHHHHHHH
LVNWDFVASNFA
HHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8181762; 12910271 [H]