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The map label for this gene is pheC [H]

Identifier: 17547231

GI number: 17547231

Start: 2718791

End: 2719594

Strand: Direct

Name: pheC [H]

Synonym: RSc2512

Alternate gene names: 17547231

Gene position: 2718791-2719594 (Clockwise)

Preceding gene: 17547230

Following gene: 17547233

Centisome position: 73.16

GC content: 65.67

Gene sequence:

>804_bases
ATGTTTGTCCGCTTCATCCGCAGCACCGCCCTGCTGCTGTGCGCCTGCGTTGCCGCGCCGGCCCTGGCGCAGGCCACCAA
CCGCCTCGACGAGATCCTTGCGCGCGGCACGCTGCGCGTCGGCTCCACGGGCGACTACAAGCCCTTCAGCTACAAGACGC
CCGGCGACGGCCGCTTCATCGGCCTGGACGTGGACATGGGCGAACGGCTGGCGAAGGCCCTCGGCGTGAAGCTGGAAGTG
GTGCCGACCACGTGGTCGACGCTGATGCGCGATTTCGGCGAAGACCGCTTCGACATTGCCATGAGCGGCATCTCGGTGAC
GCTGGAACGGCAGAAGAAGGCGTTCTATTCGATCCCGTACCAGCGCGACGGCAAGACGCCGATCGCCCGCTGCGAGAACC
AGGACAAGTTCCAGACCCTGGAACAGATCGACCGGCCCGGCGTGCGGGCGGTGGTCAACCCGGGCGGCACCAACGAGAAG
TTCGCGCGCGAACACCTGAAACAGGCGCAGATCCGCGTGTATCCGGACAACGTGACGATCTTCAACGAGATCATCGCCGG
ACGCGCCGACCTGATGATGACCGATGCGGTCGAGACGCGGCTGCAGCAGAAGCTGCACCCGGAACTGTGCGCCGTGCATC
CCGACGCGCCGTTCGATTTCTCTGAGAAGGCCTACCTGCTGCCGCGCGACGTGGTGTTCAAGAACTTCGTCGATCAGTGG
CTGCGGCAGACGATGGAGAGCGGCGAGTTCGCGCGCCGCTTCGATGCCTGGCTGGCGTATCCGTGGAACGCGCCCGCCAA
GTGA

Upstream 100 bases:

>100_bases
CTGCAGTGGAACAAGGCCGCCGGCCAATCGAGCTAGCATGCGAAGGTGCGTGGCCCGGGTCGAGGCCGCGCCCGAGCCTT
TTTCATTGACGGGAGTCCCC

Downstream 100 bases:

>100_bases
ACTAAGCCGCGGCGGCCGGGACCGCCCCCGGCATCAGTGCAGCGCGGGTTGATTCCCGTGCTGCAGCGCCAGCGCATCGC
GCAGCAGCGCATCGGTCATG

Product: cyclohexadienyl dehydratase precursor signal peptide protein

Products: NA

Alternate protein names: Prephenate dehydratase; Arogenate dehydratase [H]

Number of amino acids: Translated: 267; Mature: 267

Protein sequence:

>267_residues
MFVRFIRSTALLLCACVAAPALAQATNRLDEILARGTLRVGSTGDYKPFSYKTPGDGRFIGLDVDMGERLAKALGVKLEV
VPTTWSTLMRDFGEDRFDIAMSGISVTLERQKKAFYSIPYQRDGKTPIARCENQDKFQTLEQIDRPGVRAVVNPGGTNEK
FAREHLKQAQIRVYPDNVTIFNEIIAGRADLMMTDAVETRLQQKLHPELCAVHPDAPFDFSEKAYLLPRDVVFKNFVDQW
LRQTMESGEFARRFDAWLAYPWNAPAK

Sequences:

>Translated_267_residues
MFVRFIRSTALLLCACVAAPALAQATNRLDEILARGTLRVGSTGDYKPFSYKTPGDGRFIGLDVDMGERLAKALGVKLEV
VPTTWSTLMRDFGEDRFDIAMSGISVTLERQKKAFYSIPYQRDGKTPIARCENQDKFQTLEQIDRPGVRAVVNPGGTNEK
FAREHLKQAQIRVYPDNVTIFNEIIAGRADLMMTDAVETRLQQKLHPELCAVHPDAPFDFSEKAYLLPRDVVFKNFVDQW
LRQTMESGEFARRFDAWLAYPWNAPAK
>Mature_267_residues
MFVRFIRSTALLLCACVAAPALAQATNRLDEILARGTLRVGSTGDYKPFSYKTPGDGRFIGLDVDMGERLAKALGVKLEV
VPTTWSTLMRDFGEDRFDIAMSGISVTLERQKKAFYSIPYQRDGKTPIARCENQDKFQTLEQIDRPGVRAVVNPGGTNEK
FAREHLKQAQIRVYPDNVTIFNEIIAGRADLMMTDAVETRLQQKLHPELCAVHPDAPFDFSEKAYLLPRDVVFKNFVDQW
LRQTMESGEFARRFDAWLAYPWNAPAK

Specific function: Forms alternative pathway for phenylalanine biosynthesis. Can catalyze two reactions:prephenate dehydratase and arogenate dehydratase. May have a role in chemotaxis or transport [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 3 family [H]

Homologues:

Organism=Escherichia coli, GI1788228, Length=186, Percent_Identity=29.5698924731183, Blast_Score=99, Evalue=2e-22,
Organism=Escherichia coli, GI1787031, Length=184, Percent_Identity=27.1739130434783, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1788648, Length=164, Percent_Identity=29.8780487804878, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1788649, Length=165, Percent_Identity=28.4848484848485, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI171474010, Length=197, Percent_Identity=28.9340101522843, Blast_Score=62, Evalue=3e-11,

Paralogues:

None

Copy number: 1920 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1060 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 80 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015683
- InterPro:   IPR001638
- InterPro:   IPR018313 [H]

Pfam domain/function: PF00497 SBP_bac_3 [H]

EC number: =4.2.1.51; =4.2.1.91 [H]

Molecular weight: Translated: 30242; Mature: 30242

Theoretical pI: Translated: 8.30; Mature: 8.30

Prosite motif: PS01039 SBP_BACTERIAL_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFVRFIRSTALLLCACVAAPALAQATNRLDEILARGTLRVGSTGDYKPFSYKTPGDGRFI
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEECCCCCCCCCCCCCCCCCEEE
GLDVDMGERLAKALGVKLEVVPTTWSTLMRDFGEDRFDIAMSGISVTLERQKKAFYSIPY
EEECCHHHHHHHHHCCEEEEECCCHHHHHHHHCCCHHHEEECCCEEEHHHHHHHHHCCCC
QRDGKTPIARCENQDKFQTLEQIDRPGVRAVVNPGGTNEKFAREHLKQAQIRVYPDNVTI
CCCCCCHHHHCCCCHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHHCCEEEECCCHHH
FNEIIAGRADLMMTDAVETRLQQKLHPELCAVHPDAPFDFSEKAYLLPRDVVFKNFVDQW
HHHHHHCCHHHHHHHHHHHHHHHHHCHHHEEECCCCCCCCCCCCEECHHHHHHHHHHHHH
LRQTMESGEFARRFDAWLAYPWNAPAK
HHHHHHCCHHHHHHHHHEECCCCCCCC
>Mature Secondary Structure
MFVRFIRSTALLLCACVAAPALAQATNRLDEILARGTLRVGSTGDYKPFSYKTPGDGRFI
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEECCCCCCCCCCCCCCCCCEEE
GLDVDMGERLAKALGVKLEVVPTTWSTLMRDFGEDRFDIAMSGISVTLERQKKAFYSIPY
EEECCHHHHHHHHHCCEEEEECCCHHHHHHHHCCCHHHEEECCCEEEHHHHHHHHHCCCC
QRDGKTPIARCENQDKFQTLEQIDRPGVRAVVNPGGTNEKFAREHLKQAQIRVYPDNVTI
CCCCCCHHHHCCCCHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHHCCEEEECCCHHH
FNEIIAGRADLMMTDAVETRLQQKLHPELCAVHPDAPFDFSEKAYLLPRDVVFKNFVDQW
HHHHHHCCHHHHHHHHHHHHHHHHHCHHHEEECCCCCCCCCCCCEECHHHHHHHHHHHHH
LRQTMESGEFARRFDAWLAYPWNAPAK
HHHHHHCCHHHHHHHHHEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1733946; 10984043; 8515238; 7604006 [H]