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The map label for this gene is braE [H]

Identifier: 17547158

GI number: 17547158

Start: 2644714

End: 2645850

Strand: Reverse

Name: braE [H]

Synonym: RSc2439

Alternate gene names: 17547158

Gene position: 2645850-2644714 (Counterclockwise)

Preceding gene: 17547159

Following gene: 17547157

Centisome position: 71.19

GC content: 64.29

Gene sequence:

>1137_bases
ATGACAGAAACTGCAACGGAATTCAAAGCGCCGAAGAAGACGCGCGCCGCGCTTCTCGGCTTCTTCGTCCTCGCCATCTT
CGCCCCGTTCCTCGTGGGCGCCGTCGGCGGGAACTACTGGGTACGCGTGCTGGACTTCGCACTGCTGTACATCATGCTGG
CCCTGGGCCTGAACATCGTGGTGGGTTTTGCCGGCCTGCTCGACCTGGGCTACATCGCGTTCTACGCGGTGGGCGCCTAC
ATGATGGCGCTGCTGGGCTCGCCGCACCTGACCAACCAGTTCGAGTGGATCCATCAGCTGTTCCCGAACGGGCTGCATCT
GCTGATCTGGTGGGTGATCCCGCTGGGCGCGGGGCTGGCGGCGCTGTTCGGCATCCTGCTGGGGGCGCCGACGCTCAAGC
TGCGCGGCGACTACCTCGCCATCGTGACGCTGGGCTTCGGCGAGATCATCCGCATCTTCATGAACAACCTCGACCGCCCG
GTGAACATCACCAACGGTCCGAAGGGCGTCAACCTGATCGAGCCGGTCAAGCTCTTCGGGTTCGACTTCTCGAAGCGGCA
TGACATCTTCGGCATCCACTTCGAGCCGGTGCACATGTACTACTACCTGTTCGTGCTGCTGGCGATGGGCATCATCACGG
TGTGCCTGCGCCTGCAGAATTCGCGGATCGGTCGTGCATGGGTTGCCATCCGCGAGGACGAGATCGCCGCCAAGGCCATG
GGCATCAACACCCGCAACATCAAGCTGCTGGCGTTCGCCATGGGTGCGTCGTTCGGCGGCGTGTCGGGGGCGATGTTCGC
GTCGTTCCAGGGCTTCGTGTCGCCGGAATCGTTCGTGCTGTGGGAGTCGATCTACATCCTGGCCATCGTGGTGCTGGGCG
GCATGGGCCATATCCCGGGCGTGATCCTGGGCGGCATCCTGCTGGTGGGCTTCCAGGAACTGCTGCGCGCGCTGGCCGAG
CCGATCCAGAACAAGCTGTTCGGCCACGTGATCGTGGAAGCGGAAGTGCTGCGTCAGCTGCTGTTCGGCCTGGCGATGGT
GGGGGTGATGCTGTATCGCCCCGCGGGCCTGTGGCCCTCGCCGCGCAAGGAAGACCGCCCGCAGAAGGCGCGGGTCGGTG
GTTTGTCCCGCATCTGA

Upstream 100 bases:

>100_bases
GATGTGTTCGCGTTCATTGTGCTGATTTGCGTGCTGCTGTTCCGCCCGTCCGGCATCATGGGCGAACGCGTTGCAGACCG
TGCATAAGAAGGGGAGCGCC

Downstream 100 bases:

>100_bases
TGGAGGCACGCACATGAGCAACAACAACCTCCTCTCGATCCGGGGAGTCAACAAGCGCTTCGGCGGCCTGCAGGCGCTGT
CGGACGTGAGCCTGGAGATC

Product: amino-acid transmembrane ABC transporter protein

Products: ADP; phosphate; L-valine [Cytoplasm]; ADP; L-iso-leucine [Cytoplasm]; L-leucine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 378; Mature: 377

Protein sequence:

>378_residues
MTETATEFKAPKKTRAALLGFFVLAIFAPFLVGAVGGNYWVRVLDFALLYIMLALGLNIVVGFAGLLDLGYIAFYAVGAY
MMALLGSPHLTNQFEWIHQLFPNGLHLLIWWVIPLGAGLAALFGILLGAPTLKLRGDYLAIVTLGFGEIIRIFMNNLDRP
VNITNGPKGVNLIEPVKLFGFDFSKRHDIFGIHFEPVHMYYYLFVLLAMGIITVCLRLQNSRIGRAWVAIREDEIAAKAM
GINTRNIKLLAFAMGASFGGVSGAMFASFQGFVSPESFVLWESIYILAIVVLGGMGHIPGVILGGILLVGFQELLRALAE
PIQNKLFGHVIVEAEVLRQLLFGLAMVGVMLYRPAGLWPSPRKEDRPQKARVGGLSRI

Sequences:

>Translated_378_residues
MTETATEFKAPKKTRAALLGFFVLAIFAPFLVGAVGGNYWVRVLDFALLYIMLALGLNIVVGFAGLLDLGYIAFYAVGAY
MMALLGSPHLTNQFEWIHQLFPNGLHLLIWWVIPLGAGLAALFGILLGAPTLKLRGDYLAIVTLGFGEIIRIFMNNLDRP
VNITNGPKGVNLIEPVKLFGFDFSKRHDIFGIHFEPVHMYYYLFVLLAMGIITVCLRLQNSRIGRAWVAIREDEIAAKAM
GINTRNIKLLAFAMGASFGGVSGAMFASFQGFVSPESFVLWESIYILAIVVLGGMGHIPGVILGGILLVGFQELLRALAE
PIQNKLFGHVIVEAEVLRQLLFGLAMVGVMLYRPAGLWPSPRKEDRPQKARVGGLSRI
>Mature_377_residues
TETATEFKAPKKTRAALLGFFVLAIFAPFLVGAVGGNYWVRVLDFALLYIMLALGLNIVVGFAGLLDLGYIAFYAVGAYM
MALLGSPHLTNQFEWIHQLFPNGLHLLIWWVIPLGAGLAALFGILLGAPTLKLRGDYLAIVTLGFGEIIRIFMNNLDRPV
NITNGPKGVNLIEPVKLFGFDFSKRHDIFGIHFEPVHMYYYLFVLLAMGIITVCLRLQNSRIGRAWVAIREDEIAAKAMG
INTRNIKLLAFAMGASFGGVSGAMFASFQGFVSPESFVLWESIYILAIVVLGGMGHIPGVILGGILLVGFQELLRALAEP
IQNKLFGHVIVEAEVLRQLLFGLAMVGVMLYRPAGLWPSPRKEDRPQKARVGGLSRI

Specific function: Component of the high affinity leucine, isoleucine, valine, transport system (LIV-I), which is operative without Na(+) and is specific for alanine and threonine, in addition to branched-chain amino acids [H]

COG id: COG4177

COG function: function code E; ABC-type branched-chain amino acid transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. LivHM subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789865, Length=346, Percent_Identity=40.7514450867052, Blast_Score=216, Evalue=2e-57,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001851
- InterPro:   IPR021807 [H]

Pfam domain/function: PF02653 BPD_transp_2; PF11862 DUF3382 [H]

EC number: NA

Molecular weight: Translated: 41494; Mature: 41363

Theoretical pI: Translated: 9.84; Mature: 9.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTETATEFKAPKKTRAALLGFFVLAIFAPFLVGAVGGNYWVRVLDFALLYIMLALGLNIV
CCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
VGFAGLLDLGYIAFYAVGAYMMALLGSPHLTNQFEWIHQLFPNGLHLLIWWVIPLGAGLA
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHCCHHH
ALFGILLGAPTLKLRGDYLAIVTLGFGEIIRIFMNNLDRPVNITNGPKGVNLIEPVKLFG
HHHHHHHCCCCEEECCCEEEEEEHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHC
FDFSKRHDIFGIHFEPVHMYYYLFVLLAMGIITVCLRLQNSRIGRAWVAIREDEIAAKAM
CCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHEEEEEHHHHHHHHH
GINTRNIKLLAFAMGASFGGVSGAMFASFQGFVSPESFVLWESIYILAIVVLGGMGHIPG
CCCCCCEEEEEEECCCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCHHH
VILGGILLVGFQELLRALAEPIQNKLFGHVIVEAEVLRQLLFGLAMVGVMLYRPAGLWPS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
PRKEDRPQKARVGGLSRI
CCCCCCCHHHHCCCCCCC
>Mature Secondary Structure 
TETATEFKAPKKTRAALLGFFVLAIFAPFLVGAVGGNYWVRVLDFALLYIMLALGLNIV
CCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
VGFAGLLDLGYIAFYAVGAYMMALLGSPHLTNQFEWIHQLFPNGLHLLIWWVIPLGAGLA
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHCCHHH
ALFGILLGAPTLKLRGDYLAIVTLGFGEIIRIFMNNLDRPVNITNGPKGVNLIEPVKLFG
HHHHHHHCCCCEEECCCEEEEEEHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHC
FDFSKRHDIFGIHFEPVHMYYYLFVLLAMGIITVCLRLQNSRIGRAWVAIREDEIAAKAM
CCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHEEEEEHHHHHHHHH
GINTRNIKLLAFAMGASFGGVSGAMFASFQGFVSPESFVLWESIYILAIVVLGGMGHIPG
CCCCCCEEEEEEECCCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCHHH
VILGGILLVGFQELLRALAEPIQNKLFGHVIVEAEVLRQLLFGLAMVGVMLYRPAGLWPS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
PRKEDRPQKARVGGLSRI
CCCCCCCHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; L-valine [Periplasm]; H2O; ATP; L-iso-leucine [Periplasm]; L-leucine [Periplasm] [C]

Specific reaction: ATP + L-valine [Periplasm] + H2O = ADP + phosphate + L-valine [Cytoplasm] ATP + L-iso-leucine [Periplasm] + H2O = ADP + phosphate + L-iso-leucine [Cytoplasm] ATP + L-leucine [Periplasm] + H2O = ADP + phosphate + L-leucine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2120183; 10984043 [H]