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The map label for this gene is holC [H]

Identifier: 17547133

GI number: 17547133

Start: 2618962

End: 2619390

Strand: Reverse

Name: holC [H]

Synonym: RSc2414

Alternate gene names: 17547133

Gene position: 2619390-2618962 (Counterclockwise)

Preceding gene: 17547134

Following gene: 17547132

Centisome position: 70.48

GC content: 68.07

Gene sequence:

>429_bases
ATGACCCGTGTCGATTTCCATAGCAACGTGCCCGGCAAGCTGGCTTATGCCTGCCGCCTGGTGCGCAAGGCCTACGGCGC
GGGCCAGAAGGTGATCGTGGTGGGGAACCGCGCAGCGCTGGAGGCCTTTGACGCCCAGTTGTGGACCTTCAGCCAGCTCG
ACTTCCTGCCGCACTGCGGGCTGCGGCATCGGCTCGCCGCGCAGACGCCGATTCTGCTGGCCGATGCCTCCGAGCCGCTG
GACGACGCGCCCCATCACGACATTCTCGTCAACCTGTCGGATGCCACGCCGCCGCTGTTCGCGCGGTTCGCGCGCCTGAT
CGAAATCGTCGGCGACGACGAGGCCGAGCGCGCCGCCGCCCGCGACCGCTTCCGCTTCTATCGCGACCGCGGCTATCCGA
TCCAACATCACGACGTGGGGCGCGCATGA

Upstream 100 bases:

>100_bases
AGCGGCGCGGCCAAGGGCGCCACCGGCCGCCCGGTGCCGCTGCTCACGCGCTTCCTGATGGATCGCGCCGGCTGATGCGC
TGACCGGAGCAGGCCCGCCC

Downstream 100 bases:

>100_bases
CTCCCGATGGCCGTAATCCCGGACCCAACGCGGACAACAACATCCCCGTCCTGACGGAGATCGTCGAGCTCGAGACGCAG
GTGCCGGCGCAAGCGCCGCC

Product: DNA polymerase III subunit chi

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 142; Mature: 141

Protein sequence:

>142_residues
MTRVDFHSNVPGKLAYACRLVRKAYGAGQKVIVVGNRAALEAFDAQLWTFSQLDFLPHCGLRHRLAAQTPILLADASEPL
DDAPHHDILVNLSDATPPLFARFARLIEIVGDDEAERAAARDRFRFYRDRGYPIQHHDVGRA

Sequences:

>Translated_142_residues
MTRVDFHSNVPGKLAYACRLVRKAYGAGQKVIVVGNRAALEAFDAQLWTFSQLDFLPHCGLRHRLAAQTPILLADASEPL
DDAPHHDILVNLSDATPPLFARFARLIEIVGDDEAERAAARDRFRFYRDRGYPIQHHDVGRA
>Mature_141_residues
TRVDFHSNVPGKLAYACRLVRKAYGAGQKVIVVGNRAALEAFDAQLWTFSQLDFLPHCGLRHRLAAQTPILLADASEPLD
DAPHHDILVNLSDATPPLFARFARLIEIVGDDEAERAAARDRFRFYRDRGYPIQHHDVGRA

Specific function: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity [H]

COG id: COG2927

COG function: function code L; DNA polymerase III, chi subunit

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007459 [H]

Pfam domain/function: PF04364 DNA_pol3_chi [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 15931; Mature: 15800

Theoretical pI: Translated: 7.71; Mature: 7.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRVDFHSNVPGKLAYACRLVRKAYGAGQKVIVVGNRAALEAFDAQLWTFSQLDFLPHCG
CCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHHHCCCCCCC
LRHRLAAQTPILLADASEPLDDAPHHDILVNLSDATPPLFARFARLIEIVGDDEAERAAA
CHHHHHCCCCEEEECCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHCCCHHHHHHH
RDRFRFYRDRGYPIQHHDVGRA
HHHHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure 
TRVDFHSNVPGKLAYACRLVRKAYGAGQKVIVVGNRAALEAFDAQLWTFSQLDFLPHCG
CCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHHHCCCCCCC
LRHRLAAQTPILLADASEPLDDAPHHDILVNLSDATPPLFARFARLIEIVGDDEAERAAA
CHHHHHCCCCEEEECCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHCCCHHHHHHH
RDRFRFYRDRGYPIQHHDVGRA
HHHHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9864319; 10984043 [H]