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The map label for this gene is mrp [H]

Identifier: 17547098

GI number: 17547098

Start: 2583017

End: 2584105

Strand: Reverse

Name: mrp [H]

Synonym: RSc2379

Alternate gene names: 17547098

Gene position: 2584105-2583017 (Counterclockwise)

Preceding gene: 17547101

Following gene: 17547097

Centisome position: 69.53

GC content: 67.03

Gene sequence:

>1089_bases
TTGAGCCTGACCGTCGAACAGATCACCGAAGCCCTGCGCGGCGTGGTGGACCCCAATACCGGGCGCGACCTGGTGTCCTC
CAAGTCGGTGCGCAACGTCCGGGTCGACGGCGGCGACGTGTCGCTGGATGTCGAGCTCGGGTACCCGGCCAGGAGCCAGT
TCGAGCCGATCCGCAAGCTGGTGATCGGCGCGCTGCGCCAGGTCGGCGGCGTCGCCAATGTCAGCGTGCAGGTGTCGATG
AAGATCGTCGCGCATGCGGTGCAGCGCGGCGTGCACCTGCTGCCGAACGTGAAGAACATCATCGCGGTGGCCTCGGGCAA
GGGCGGCGTGGGCAAGTCGACCACGGCCGTGAACCTGGCGCTGGCGCTGGCCGCCGAAGGGGCCAGCGTGGGCATGCTCG
ATGCCGACATCTACGGCCCCAGCCAGCCGATGATGCTGGGCATCCAGGGGCAGCCGGAATCCACCGATGGCAAGACCATG
GAGCCGATGGAAGGCCATGGCATCCAGGCCAACTCGATCGGCTTCCTGATCGAGCAGGACAACCCGATGGTGTGGCGCGG
CCCGATGGTCACCTCCGCGCTGGAGCAGTTGCTCAAGCAGACCAACTGGCGCGACCTGGATTACCTCATCGTCGACATGC
CGCCGGGCACGGGCGACATCCAGCTCACGCTGTCGCAGAAGGTGCCCGTGACGGGCGCGGTGATCGTCACCACGCCGCAG
GACATCGCGCTGATCGACGCCAAGAAGGGGCTGAAGATGTTCGAGAAGGTGGGCATCCCCATCATCGGCGTGGTGGAGAA
CATGGCGGTCTACTGCTGCCCGAACTGCGGCCACACCGAGCACATCTTCGGCGCGGGTGGCGGCGAGAAGATGTGCGCGC
AGTACGGCGTGCCCTTCCTCGGCAGCCTGCCGCTGAACCTGTCGATCCGCGAGCAGGCGGACGCGGGCCGGCCGACCGTG
GTGGCCGATCCGGACGGTGCCATCGCCGACATCTACAGGGCGATCGCGCGGCGCGTTGCCATCACCGTCGCCGAGAAGGC
GAAGGACATGACCAGCAAGTTCCCGTCGATCGTGGTGCAGAACACCTGA

Upstream 100 bases:

>100_bases
AGCAAAACAGTACATAGAGTGGCCAGGGCGCCGCAAAGTTCATGCGTCGCAACCGTTGGGCCGTCCCTCATTCGCATTAA
AATTCTTGCTGGAGTGCAAC

Downstream 100 bases:

>100_bases
GGCCCATCGTGGATACGCCCGCCGAGCCGCTGCCGACCGAACACCCGTCCGTGCGCGTGGCGGTGGTGCTGTGCCGCCGG
CCGACGGGCAACCGCTGGCA

Product: MRP family ATP-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 362; Mature: 361

Protein sequence:

>362_residues
MSLTVEQITEALRGVVDPNTGRDLVSSKSVRNVRVDGGDVSLDVELGYPARSQFEPIRKLVIGALRQVGGVANVSVQVSM
KIVAHAVQRGVHLLPNVKNIIAVASGKGGVGKSTTAVNLALALAAEGASVGMLDADIYGPSQPMMLGIQGQPESTDGKTM
EPMEGHGIQANSIGFLIEQDNPMVWRGPMVTSALEQLLKQTNWRDLDYLIVDMPPGTGDIQLTLSQKVPVTGAVIVTTPQ
DIALIDAKKGLKMFEKVGIPIIGVVENMAVYCCPNCGHTEHIFGAGGGEKMCAQYGVPFLGSLPLNLSIREQADAGRPTV
VADPDGAIADIYRAIARRVAITVAEKAKDMTSKFPSIVVQNT

Sequences:

>Translated_362_residues
MSLTVEQITEALRGVVDPNTGRDLVSSKSVRNVRVDGGDVSLDVELGYPARSQFEPIRKLVIGALRQVGGVANVSVQVSM
KIVAHAVQRGVHLLPNVKNIIAVASGKGGVGKSTTAVNLALALAAEGASVGMLDADIYGPSQPMMLGIQGQPESTDGKTM
EPMEGHGIQANSIGFLIEQDNPMVWRGPMVTSALEQLLKQTNWRDLDYLIVDMPPGTGDIQLTLSQKVPVTGAVIVTTPQ
DIALIDAKKGLKMFEKVGIPIIGVVENMAVYCCPNCGHTEHIFGAGGGEKMCAQYGVPFLGSLPLNLSIREQADAGRPTV
VADPDGAIADIYRAIARRVAITVAEKAKDMTSKFPSIVVQNT
>Mature_361_residues
SLTVEQITEALRGVVDPNTGRDLVSSKSVRNVRVDGGDVSLDVELGYPARSQFEPIRKLVIGALRQVGGVANVSVQVSMK
IVAHAVQRGVHLLPNVKNIIAVASGKGGVGKSTTAVNLALALAAEGASVGMLDADIYGPSQPMMLGIQGQPESTDGKTME
PMEGHGIQANSIGFLIEQDNPMVWRGPMVTSALEQLLKQTNWRDLDYLIVDMPPGTGDIQLTLSQKVPVTGAVIVTTPQD
IALIDAKKGLKMFEKVGIPIIGVVENMAVYCCPNCGHTEHIFGAGGGEKMCAQYGVPFLGSLPLNLSIREQADAGRPTVV
ADPDGAIADIYRAIARRVAITVAEKAKDMTSKFPSIVVQNT

Specific function: Not Known. [C]

COG id: COG0489

COG function: function code D; ATPases involved in chromosome partitioning

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Mrp/NBP35 ATP-binding proteins family [H]

Homologues:

Organism=Homo sapiens, GI157384956, Length=245, Percent_Identity=55.9183673469388, Blast_Score=280, Evalue=2e-75,
Organism=Homo sapiens, GI118572611, Length=262, Percent_Identity=39.3129770992366, Blast_Score=186, Evalue=4e-47,
Organism=Homo sapiens, GI6912540, Length=253, Percent_Identity=39.5256916996047, Blast_Score=182, Evalue=5e-46,
Organism=Escherichia coli, GI87082045, Length=342, Percent_Identity=53.2163742690059, Blast_Score=338, Evalue=2e-94,
Organism=Caenorhabditis elegans, GI25143050, Length=257, Percent_Identity=40.8560311284047, Blast_Score=189, Evalue=3e-48,
Organism=Saccharomyces cerevisiae, GI6322188, Length=259, Percent_Identity=34.7490347490347, Blast_Score=183, Evalue=4e-47,
Organism=Saccharomyces cerevisiae, GI6321347, Length=242, Percent_Identity=41.3223140495868, Blast_Score=172, Evalue=8e-44,
Organism=Drosophila melanogaster, GI221511043, Length=250, Percent_Identity=41.2, Blast_Score=209, Evalue=3e-54,
Organism=Drosophila melanogaster, GI24667611, Length=256, Percent_Identity=41.796875, Blast_Score=192, Evalue=2e-49,
Organism=Drosophila melanogaster, GI19921440, Length=242, Percent_Identity=40.0826446280992, Blast_Score=159, Evalue=3e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019591
- InterPro:   IPR000808 [H]

Pfam domain/function: PF10609 ParA [H]

EC number: NA

Molecular weight: Translated: 38258; Mature: 38127

Theoretical pI: Translated: 6.05; Mature: 6.05

Prosite motif: PS01215 MRP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLTVEQITEALRGVVDPNTGRDLVSSKSVRNVRVDGGDVSLDVELGYPARSQFEPIRKL
CCCCHHHHHHHHHCCCCCCCCHHHHCCCCCCEEEECCCCEEEEEEECCCCHHHHHHHHHH
VIGALRQVGGVANVSVQVSMKIVAHAVQRGVHLLPNVKNIIAVASGKGGVGKSTTAVNLA
HHHHHHHHCCEEEEEEEEHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCCCCCCHHEEEE
LALAAEGASVGMLDADIYGPSQPMMLGIQGQPESTDGKTMEPMEGHGIQANSIGFLIEQD
EEEEECCCCEEEEEECCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCEEECCEEEEEECC
NPMVWRGPMVTSALEQLLKQTNWRDLDYLIVDMPPGTGDIQLTLSQKVPVTGAVIVTTPQ
CCEEEECCHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCEEEEEECCCCCEEEEEEECCC
DIALIDAKKGLKMFEKVGIPIIGVVENMAVYCCPNCGHTEHIFGAGGGEKMCAQYGVPFL
CEEEEECHHHHHHHHHCCCCEEEECCCCEEEECCCCCCCCEEEECCCCHHHHHHCCCCCC
GSLPLNLSIREQADAGRPTVVADPDGAIADIYRAIARRVAITVAEKAKDMTSKFPSIVVQ
CCCCCCEEEECCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEE
NT
CC
>Mature Secondary Structure 
SLTVEQITEALRGVVDPNTGRDLVSSKSVRNVRVDGGDVSLDVELGYPARSQFEPIRKL
CCCHHHHHHHHHCCCCCCCCHHHHCCCCCCEEEECCCCEEEEEEECCCCHHHHHHHHHH
VIGALRQVGGVANVSVQVSMKIVAHAVQRGVHLLPNVKNIIAVASGKGGVGKSTTAVNLA
HHHHHHHHCCEEEEEEEEHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCCCCCCHHEEEE
LALAAEGASVGMLDADIYGPSQPMMLGIQGQPESTDGKTMEPMEGHGIQANSIGFLIEQD
EEEEECCCCEEEEEECCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCEEECCEEEEEECC
NPMVWRGPMVTSALEQLLKQTNWRDLDYLIVDMPPGTGDIQLTLSQKVPVTGAVIVTTPQ
CCEEEECCHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCEEEEEECCCCCEEEEEEECCC
DIALIDAKKGLKMFEKVGIPIIGVVENMAVYCCPNCGHTEHIFGAGGGEKMCAQYGVPFL
CEEEEECHHHHHHHHHCCCCEEEECCCCEEEECCCCCCCCEEEECCCCHHHHHHCCCCCC
GSLPLNLSIREQADAGRPTVVADPDGAIADIYRAIARRVAITVAEKAKDMTSKFPSIVVQ
CCCCCCEEEECCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEE
NT
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]