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The map label for this gene is sigK [H]

Identifier: 17547080

GI number: 17547080

Start: 2564603

End: 2565244

Strand: Direct

Name: sigK [H]

Synonym: RSc2361

Alternate gene names: 17547080

Gene position: 2564603-2565244 (Clockwise)

Preceding gene: 17547077

Following gene: 17547081

Centisome position: 69.01

GC content: 73.36

Gene sequence:

>642_bases
GTGCCCAGCCTCGAACGCACCGCCGCAGACCATGCAGGGCAGGACGCCGGCCGGCCGCCCATCGCCGCCCGCGCCCCGGG
CGCGGAAGCGGACGAGCTCGCGGCCCTGCTCCAGCGCATCGGCCTGGGCGAGCGCGAGGCCCTGCGCGCCCTGTACGCGC
GCTGCGCAGCGAAACTGTTCGGGCTTGCGCTGCGTATCTTGGTCCGACGGGACTGGGCCGAGGATGTCTTGCAGGAAAGC
TTCGTCAACATCTGGCGCCACGCCGCCGACTACCGGCCGCAGCTGGCCGCGCCGATGACGTGGATGGCCACCATCGTGCG
CAACCGCGCCCTCGACTGCCTGCGCCGGCAGCGCGCCGAGCGCGTGGCGGAATCGGTGCCGCTCGACGATGCCCACGCGG
ACGCGCTGGCCGACCACGCCCCCGGCCCCGCCGACCTGGCGCTGGCCGGGCAACAGGCACGCGCCCTGGCCGAATGCCTG
AAGCGCCTCGACCCGCGGCAGCGCGAAGTGGTCTCGCTGGCCTATCTGCGTGACCTGTCGCACAGCGAACTGGCGCAGGT
GCTATCCGTGCCGCTGGGCACGGTGAAATCGTGGATGCGGCGCGGCCTGGACCGCCTGCGCGAATGCCTGGGGACGCCTT
GA

Upstream 100 bases:

>100_bases
GAAACGGATGCAGACCACGGCGCAGCCCCGGGGAATGCCCGCCCACGGGGGTGATGGTTTCTTCCTACAATGGCCACAGC
ATCCTCACGACGACCCGCCC

Downstream 100 bases:

>100_bases
TGGACCCGCGACGCCAACCCGACCTGATCGACCGGCTCGCCGCCGAATACGCGGTCGGCACGCTGCGCGCGGGCGCCCGC
CGGCGCTTCGAGCAGCTGAT

Product: RNA polymerase sigma-E factor sigma-24 homolog transcription regulator protein

Products: NA

Alternate protein names: Sigma-K factor [H]

Number of amino acids: Translated: 213; Mature: 212

Protein sequence:

>213_residues
MPSLERTAADHAGQDAGRPPIAARAPGAEADELAALLQRIGLGEREALRALYARCAAKLFGLALRILVRRDWAEDVLQES
FVNIWRHAADYRPQLAAPMTWMATIVRNRALDCLRRQRAERVAESVPLDDAHADALADHAPGPADLALAGQQARALAECL
KRLDPRQREVVSLAYLRDLSHSELAQVLSVPLGTVKSWMRRGLDRLRECLGTP

Sequences:

>Translated_213_residues
MPSLERTAADHAGQDAGRPPIAARAPGAEADELAALLQRIGLGEREALRALYARCAAKLFGLALRILVRRDWAEDVLQES
FVNIWRHAADYRPQLAAPMTWMATIVRNRALDCLRRQRAERVAESVPLDDAHADALADHAPGPADLALAGQQARALAECL
KRLDPRQREVVSLAYLRDLSHSELAQVLSVPLGTVKSWMRRGLDRLRECLGTP
>Mature_212_residues
PSLERTAADHAGQDAGRPPIAARAPGAEADELAALLQRIGLGEREALRALYARCAAKLFGLALRILVRRDWAEDVLQESF
VNIWRHAADYRPQLAAPMTWMATIVRNRALDCLRRQRAERVAESVPLDDAHADALADHAPGPADLALAGQQARALAECLK
RLDPRQREVVSLAYLRDLSHSELAQVLSVPLGTVKSWMRRGLDRLRECLGTP

Specific function: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released [H]

COG id: COG1595

COG function: function code K; DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sigma-70 factor family. ECF subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: <10 [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014284
- InterPro:   IPR007627
- InterPro:   IPR007630
- InterPro:   IPR013325
- InterPro:   IPR013324
- InterPro:   IPR011991 [H]

Pfam domain/function: PF04542 Sigma70_r2; PF04545 Sigma70_r4 [H]

EC number: NA

Molecular weight: Translated: 23489; Mature: 23358

Theoretical pI: Translated: 8.35; Mature: 8.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPSLERTAADHAGQDAGRPPIAARAPGAEADELAALLQRIGLGEREALRALYARCAAKLF
CCCHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
GLALRILVRRDWAEDVLQESFVNIWRHAADYRPQLAAPMTWMATIVRNRALDCLRRQRAE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
RVAESVPLDDAHADALADHAPGPADLALAGQQARALAECLKRLDPRQREVVSLAYLRDLS
HHHHHCCCCHHHHHHHHHCCCCCHHHHHCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHCC
HSELAQVLSVPLGTVKSWMRRGLDRLRECLGTP
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
PSLERTAADHAGQDAGRPPIAARAPGAEADELAALLQRIGLGEREALRALYARCAAKLF
CCHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
GLALRILVRRDWAEDVLQESFVNIWRHAADYRPQLAAPMTWMATIVRNRALDCLRRQRAE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
RVAESVPLDDAHADALADHAPGPADLALAGQQARALAECLKRLDPRQREVVSLAYLRDLS
HHHHHCCCCHHHHHHHHHCCCCCHHHHHCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHCC
HSELAQVLSVPLGTVKSWMRRGLDRLRECLGTP
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA