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The map label for this gene is pecS [H]

Identifier: 17547044

GI number: 17547044

Start: 2525430

End: 2525927

Strand: Direct

Name: pecS [H]

Synonym: RSc2325

Alternate gene names: 17547044

Gene position: 2525430-2525927 (Clockwise)

Preceding gene: 17547041

Following gene: 17547047

Centisome position: 67.95

GC content: 64.26

Gene sequence:

>498_bases
ATGGACCGCGCCGCACAGGCTGTCGAACAATGGAACCGCGAGCGCCCGGACCTCGATGTCAGCTCAATGCTGCTGCTCGG
GCGTCTGGGGGAAGCAGCGCTTGTCATTGCACGTGAACGCCTGAACCCGCTGTTTGCGGAGTACGGCCTGCAGCCTGGCG
AGTTCGACGTGCTCGCTACCCTGCGCCGCTGCGGCGCACCGTACGCGCTCACGCCCACCGCGCTGTACGACGCGGCGATG
ATGTCCTCGGGTGGCATGACCAACCGCATCGACCGTCTGCAACAGGCCGGCTGGGTGGAGCGCCGCCCCAATCCTGAAGA
TGGACGCGGCACCTTGGTCGCCCTGACCAATGCGGGTTTTGCGCTGATTGACGAAGCCGTCAGCGCGCATGTCAAGAACC
AGCGTGCCGTGTTGTCGGTGCTAACGGAAGTGGAGCAGCGGCAGTTGGCGAAGTTGCTGGCGAAGTTGATCGAGGGACAG
CGAGAGGAGGAAAACTAG

Upstream 100 bases:

>100_bases
AGCTCGCTTGCGTCGTACCGCTCGGTATCGCATTATCTCGGCGTAAAGATAAAAATCATTTGTCTCGACGTCAAGATAAC
TGCTACTGGAGGAAGGGAGA

Downstream 100 bases:

>100_bases
TTCGCCAGCACTCCGCGCCGAGAATGCATTGCTCAAGAGGGGTGCGAAGAAGAAGGTCCCAGTGGTTACTTGCTAAAGAG
CCAAGGCGTTGTAGCGAGCG

Product: transcription regulator protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 165; Mature: 165

Protein sequence:

>165_residues
MDRAAQAVEQWNRERPDLDVSSMLLLGRLGEAALVIARERLNPLFAEYGLQPGEFDVLATLRRCGAPYALTPTALYDAAM
MSSGGMTNRIDRLQQAGWVERRPNPEDGRGTLVALTNAGFALIDEAVSAHVKNQRAVLSVLTEVEQRQLAKLLAKLIEGQ
REEEN

Sequences:

>Translated_165_residues
MDRAAQAVEQWNRERPDLDVSSMLLLGRLGEAALVIARERLNPLFAEYGLQPGEFDVLATLRRCGAPYALTPTALYDAAM
MSSGGMTNRIDRLQQAGWVERRPNPEDGRGTLVALTNAGFALIDEAVSAHVKNQRAVLSVLTEVEQRQLAKLLAKLIEGQ
REEEN
>Mature_165_residues
MDRAAQAVEQWNRERPDLDVSSMLLLGRLGEAALVIARERLNPLFAEYGLQPGEFDVLATLRRCGAPYALTPTALYDAAM
MSSGGMTNRIDRLQQAGWVERRPNPEDGRGTLVALTNAGFALIDEAVSAHVKNQRAVLSVLTEVEQRQLAKLLAKLIEGQ
REEEN

Specific function: Negative regulator of pectinase, cellulase, blue pigment production and virulence genes. Also binds to promoter sites in the pecS-pecM intergenic region and negatively autoregulate its expression as well as that of pecM [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH marR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87081927, Length=101, Percent_Identity=36.6336633663366, Blast_Score=65, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000835
- InterPro:   IPR023187
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01047 MarR [H]

EC number: NA

Molecular weight: Translated: 18215; Mature: 18215

Theoretical pI: Translated: 4.87; Mature: 4.87

Prosite motif: PS50995 HTH_MARR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDRAAQAVEQWNRERPDLDVSSMLLLGRLGEAALVIARERLNPLFAEYGLQPGEFDVLAT
CCHHHHHHHHHCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHH
LRRCGAPYALTPTALYDAAMMSSGGMTNRIDRLQQAGWVERRPNPEDGRGTLVALTNAGF
HHHCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCCCCCEEEEEECCCCH
ALIDEAVSAHVKNQRAVLSVLTEVEQRQLAKLLAKLIEGQREEEN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MDRAAQAVEQWNRERPDLDVSSMLLLGRLGEAALVIARERLNPLFAEYGLQPGEFDVLAT
CCHHHHHHHHHCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHH
LRRCGAPYALTPTALYDAAMMSSGGMTNRIDRLQQAGWVERRPNPEDGRGTLVALTNAGF
HHHCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCCCCCEEEEEECCCCH
ALIDEAVSAHVKNQRAVLSVLTEVEQRQLAKLLAKLIEGQREEEN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8022282; 9194707 [H]