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The map label for this gene is prpC [H]

Identifier: 17546877

GI number: 17546877

Start: 2341247

End: 2342161

Strand: Direct

Name: prpC [H]

Synonym: RSc2158

Alternate gene names: 17546877

Gene position: 2341247-2342161 (Clockwise)

Preceding gene: 17546876

Following gene: 17546878

Centisome position: 63.0

GC content: 66.01

Gene sequence:

>915_bases
ATGCGATTCTCGGTTTATCAAGAAAGCAAGAAAGGCTCGCGCCGCGTCAACCAGGACCGCATGGGGTACTGCTTCACGCG
CGATGCCATGATGATGGTGCTGTGCGACGGTCTGGGCGGACACTCCCTGGGCGAAGTGGCGGCCCAGCAGGCGCTGCAGA
CCATGGCGCGCCAGTTCCAGCGCCACGCGCGCCCGATGATCCGCAATCCGCACGACTTCCTGCACGAGAGCATCATGCTC
GCGCACCGGGAGATTCACCGCTACGCCGAAACCAACGGCCTGCCGGATGCGCCGCGCACCACCATCGTCTGTGTGCTGGC
CCAGCGCGGCTCGCTGCACTGGGCGCATGCCGGCGATTCGCGCATGTACCTGATGCGCAAGGGCGAGCTGGTGACGCGCA
CGCGCGATCACTCCAAGATCGAGAACCTACTGCAGCAGGAACGGGTGCTGCCGATGCAGGTCGCGAACCACCCCGAGCGC
AACAAGATCTACAACTGCCTGGGCTCGCCCAACCTGCCGCTGATCGACATCGGCGGCCCGACCAGCCTGGAGCCGGGCGA
CGTCGCCCTGCTGTGCTCCGACGGTCTGTGGGGCAGCGTGGCGGAAGACGAACTGGTCGACACCTGCACCAGCTTCTCGG
TCACGCAGGCGATCCCGGAGCTGATCGCCCGCGCGCTGCGCAATGCCGGCGACACCGCCGACAACACCACCGCCATCGCC
ATGATGTGGGAGCTGGACGCGACGACGACCACGCAGGATTCGGTGCAGACCGACACCCTGCCGCTGAACGCCTTCACCAC
CTCCATCCTGGACGCGCCAAAGAGCGAGTCGGGGCTGATGTCGGAAGAGGAGATCGAGCGCTCCATCGCCGAGATCCGCG
CCGCCATCGACAAGACCACCAATCTGACGCGCTGA

Upstream 100 bases:

>100_bases
ACTAAGGCCCGGCCTCGGAGTATGATTTTCAAACGATGCGGCATCGGCGGAGTCCCAGCCGGCCGCGTTGCTTCCCTTTA
CCGAATTCTCTGAAGCCGCA

Downstream 100 bases:

>100_bases
GCGTCCGCCCGCCCCCTTCCCGCCGGCCCGCCCTGCCGAACGCAGCGCGGGCCGGTATCATGTCGGGTTATCCGTTTTCC
TGCGAGACACCCACATGCGA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 304; Mature: 304

Protein sequence:

>304_residues
MRFSVYQESKKGSRRVNQDRMGYCFTRDAMMMVLCDGLGGHSLGEVAAQQALQTMARQFQRHARPMIRNPHDFLHESIML
AHREIHRYAETNGLPDAPRTTIVCVLAQRGSLHWAHAGDSRMYLMRKGELVTRTRDHSKIENLLQQERVLPMQVANHPER
NKIYNCLGSPNLPLIDIGGPTSLEPGDVALLCSDGLWGSVAEDELVDTCTSFSVTQAIPELIARALRNAGDTADNTTAIA
MMWELDATTTTQDSVQTDTLPLNAFTTSILDAPKSESGLMSEEEIERSIAEIRAAIDKTTNLTR

Sequences:

>Translated_304_residues
MRFSVYQESKKGSRRVNQDRMGYCFTRDAMMMVLCDGLGGHSLGEVAAQQALQTMARQFQRHARPMIRNPHDFLHESIML
AHREIHRYAETNGLPDAPRTTIVCVLAQRGSLHWAHAGDSRMYLMRKGELVTRTRDHSKIENLLQQERVLPMQVANHPER
NKIYNCLGSPNLPLIDIGGPTSLEPGDVALLCSDGLWGSVAEDELVDTCTSFSVTQAIPELIARALRNAGDTADNTTAIA
MMWELDATTTTQDSVQTDTLPLNAFTTSILDAPKSESGLMSEEEIERSIAEIRAAIDKTTNLTR
>Mature_304_residues
MRFSVYQESKKGSRRVNQDRMGYCFTRDAMMMVLCDGLGGHSLGEVAAQQALQTMARQFQRHARPMIRNPHDFLHESIML
AHREIHRYAETNGLPDAPRTTIVCVLAQRGSLHWAHAGDSRMYLMRKGELVTRTRDHSKIENLLQQERVLPMQVANHPER
NKIYNCLGSPNLPLIDIGGPTSLEPGDVALLCSDGLWGSVAEDELVDTCTSFSVTQAIPELIARALRNAGDTADNTTAIA
MMWELDATTTTQDSVQTDTLPLNAFTTSILDAPKSESGLMSEEEIERSIAEIRAAIDKTTNLTR

Specific function: Protein phosphatase that dephosphorylates prkC and fusA (elongation factor G). PrpC and prkC are cotranscribed, which suggests that they form a functional couple in vivo, prpC's primary role being possibly to counter the action of prkC. May be involved in

COG id: COG0631

COG function: function code T; Serine/threonine protein phosphatase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PP2C-like domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015655
- InterPro:   IPR001932
- InterPro:   IPR014045 [H]

Pfam domain/function: PF00481 PP2C [H]

EC number: =3.1.3.16 [H]

Molecular weight: Translated: 33823; Mature: 33823

Theoretical pI: Translated: 6.00; Mature: 6.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
6.6 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
6.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRFSVYQESKKGSRRVNQDRMGYCFTRDAMMMVLCDGLGGHSLGEVAAQQALQTMARQFQ
CCCCCHHHHHHHHHHCCHHHCCEEEHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHH
RHARPMIRNPHDFLHESIMLAHREIHRYAETNGLPDAPRTTIVCVLAQRGSLHWAHAGDS
HHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEECCCCEEEEECCCC
RMYLMRKGELVTRTRDHSKIENLLQQERVLPMQVANHPERNKIYNCLGSPNLPLIDIGGP
EEEEEECCCHHHCCCCHHHHHHHHHHHCCCHHHHHCCCCHHHHHHHCCCCCCCEEECCCC
TSLEPGDVALLCSDGLWGSVAEDELVDTCTSFSVTQAIPELIARALRNAGDTADNTTAIA
CCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEE
MMWELDATTTTQDSVQTDTLPLNAFTTSILDAPKSESGLMSEEEIERSIAEIRAAIDKTT
EEEECCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHC
NLTR
CCCC
>Mature Secondary Structure
MRFSVYQESKKGSRRVNQDRMGYCFTRDAMMMVLCDGLGGHSLGEVAAQQALQTMARQFQ
CCCCCHHHHHHHHHHCCHHHCCEEEHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHH
RHARPMIRNPHDFLHESIMLAHREIHRYAETNGLPDAPRTTIVCVLAQRGSLHWAHAGDS
HHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEECCCCEEEEECCCC
RMYLMRKGELVTRTRDHSKIENLLQQERVLPMQVANHPERNKIYNCLGSPNLPLIDIGGP
EEEEEECCCHHHCCCCHHHHHHHHHHHCCCHHHHHCCCCHHHHHHHCCCCCCCEEECCCC
TSLEPGDVALLCSDGLWGSVAEDELVDTCTSFSVTQAIPELIARALRNAGDTADNTTAIA
CCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEE
MMWELDATTTTQDSVQTDTLPLNAFTTSILDAPKSESGLMSEEEIERSIAEIRAAIDKTT
EEEECCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHC
NLTR
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9534248; 9384377 [H]