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The map label for this gene is dppB2 [H]

Identifier: 17546601

GI number: 17546601

Start: 2065954

End: 2066940

Strand: Direct

Name: dppB2 [H]

Synonym: RSc1882

Alternate gene names: 17546601

Gene position: 2065954-2066940 (Clockwise)

Preceding gene: 17546600

Following gene: 17546602

Centisome position: 55.59

GC content: 68.59

Gene sequence:

>987_bases
ATGACGGGCTGGCTGATCCGCCGTATCGGCCAGGCGCTGCTGGTGGTGCTGGTGATGACGGTGATCGTCTTCGTCGGCCT
GCACGCCATCGGCAACCCGGTCGACATCCTGATCGGCCAGGACGTGGACCAGGTCGACCGCGCGCGCATCATCGCCGAGC
TGGGCCTGGACAAGCCGCTGTGGCAGCAGTACCTCGCCTTCCTCAACGGCGCGCTGCACGGCAACCTCGGCAAGAGCTTC
GTCTACAACGAACCGGCCATCCAGCTGATCCTGCAGCGCCTGCCGGCCACGCTGGAGCTGGCGTTCGCGGCGCTGATCAT
CGCGGTGGCGATCGGGGTGCCGCTGGGGCTGGTCGCCGGGCTGTATCCGGGCCACCCGGTGTCGCGGCTGCTGATGACGG
GCAGCGTGGTGGGCTTTTCGCTACCGACCTTCTGGGTCGGGCTGATGCTGATCATGGCCTTCAGCGTGAGCCTGGGCTGG
CTGCCGGCCAGCGGGCGCGGCGAAACGGCCGGCTTCCTGGGCGTGCAGTGGTCGTGGCTGACGGCCGACGGGCTGCGGCA
CCTGCTGCTGCCGGCGCTCAACCTGTCGCTGTTCAAGCTGTCGCTGGTGCTGCGGCTGACCTCGGCCGGCGTGCGCGAGG
TGCTGCCGCAGGACTTCGTCAAGTTCGCGCGGGCCAAGGGGCTGTCGCCGCTGCGCGTGGTGCTGGCCCACGTGCTGCGC
AACACGCTGATCCCGCTGGTGACGGTGCTGGGGCTGGAGCTTGGCTCGACCATCGCCTTCGCGGTGGTGACGGAGAGCAT
CTTCGCGTGGCCCGGCGCGGGCAAGCTGATCCTGGACAGCATCAATACGCTGGACCGCCCGTTGATCGTCTCCTACCTGA
TCGTGGTGGTGTGCCTGTTCGTGTCGCTGAACCTGATCGTCGATGTCCTGTATCGCCTGCTCGACCCGCGCGTGCGCGCC
GCGGATGGCATGGAGGCCGCGGCATGA

Upstream 100 bases:

>100_bases
ACGCCGAGCCGGAGATCTTCGGCGACGAGTGGACGCCCGCGCCGCCGCCGCAGTCCGAGCCGGCCGCCGCGGCCGCCTCC
CCTGCCCGCGAGGCCGCGCG

Downstream 100 bases:

>100_bases
GCACGTCCCCGCAGACCGCCGCGCCCGCCCGGGCCGGCGCCGGCCCCGCGCCGCGCAGGCAGTCGCCATGGCGGCGCGTG
GCGGCGGATTTCGTGACCTC

Product: peptide ABC transporter transmembrane protein

Products: ADP; phosphate; dipeptides [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 328; Mature: 327

Protein sequence:

>328_residues
MTGWLIRRIGQALLVVLVMTVIVFVGLHAIGNPVDILIGQDVDQVDRARIIAELGLDKPLWQQYLAFLNGALHGNLGKSF
VYNEPAIQLILQRLPATLELAFAALIIAVAIGVPLGLVAGLYPGHPVSRLLMTGSVVGFSLPTFWVGLMLIMAFSVSLGW
LPASGRGETAGFLGVQWSWLTADGLRHLLLPALNLSLFKLSLVLRLTSAGVREVLPQDFVKFARAKGLSPLRVVLAHVLR
NTLIPLVTVLGLELGSTIAFAVVTESIFAWPGAGKLILDSINTLDRPLIVSYLIVVVCLFVSLNLIVDVLYRLLDPRVRA
ADGMEAAA

Sequences:

>Translated_328_residues
MTGWLIRRIGQALLVVLVMTVIVFVGLHAIGNPVDILIGQDVDQVDRARIIAELGLDKPLWQQYLAFLNGALHGNLGKSF
VYNEPAIQLILQRLPATLELAFAALIIAVAIGVPLGLVAGLYPGHPVSRLLMTGSVVGFSLPTFWVGLMLIMAFSVSLGW
LPASGRGETAGFLGVQWSWLTADGLRHLLLPALNLSLFKLSLVLRLTSAGVREVLPQDFVKFARAKGLSPLRVVLAHVLR
NTLIPLVTVLGLELGSTIAFAVVTESIFAWPGAGKLILDSINTLDRPLIVSYLIVVVCLFVSLNLIVDVLYRLLDPRVRA
ADGMEAAA
>Mature_327_residues
TGWLIRRIGQALLVVLVMTVIVFVGLHAIGNPVDILIGQDVDQVDRARIIAELGLDKPLWQQYLAFLNGALHGNLGKSFV
YNEPAIQLILQRLPATLELAFAALIIAVAIGVPLGLVAGLYPGHPVSRLLMTGSVVGFSLPTFWVGLMLIMAFSVSLGWL
PASGRGETAGFLGVQWSWLTADGLRHLLLPALNLSLFKLSLVLRLTSAGVREVLPQDFVKFARAKGLSPLRVVLAHVLRN
TLIPLVTVLGLELGSTIAFAVVTESIFAWPGAGKLILDSINTLDRPLIVSYLIVVVCLFVSLNLIVDVLYRLLDPRVRAA
DGMEAAA

Specific function: Part of the binding-protein-dependent transport system for dipeptides; probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0601

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1789965, Length=336, Percent_Identity=36.9047619047619, Blast_Score=229, Evalue=2e-61,
Organism=Escherichia coli, GI1787053, Length=320, Percent_Identity=34.6875, Blast_Score=199, Evalue=2e-52,
Organism=Escherichia coli, GI1789888, Length=330, Percent_Identity=35.7575757575758, Blast_Score=184, Evalue=5e-48,
Organism=Escherichia coli, GI1787761, Length=340, Percent_Identity=37.3529411764706, Blast_Score=163, Evalue=1e-41,
Organism=Escherichia coli, GI1787550, Length=273, Percent_Identity=31.8681318681319, Blast_Score=155, Evalue=4e-39,
Organism=Escherichia coli, GI1787497, Length=322, Percent_Identity=30.7453416149068, Blast_Score=148, Evalue=4e-37,
Organism=Escherichia coli, GI1788504, Length=285, Percent_Identity=25.2631578947368, Blast_Score=94, Evalue=9e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 35342; Mature: 35211

Theoretical pI: Translated: 9.47; Mature: 9.47

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTGWLIRRIGQALLVVLVMTVIVFVGLHAIGNPVDILIGQDVDQVDRARIIAELGLDKPL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHCCCCHH
WQQYLAFLNGALHGNLGKSFVYNEPAIQLILQRLPATLELAFAALIIAVAIGVPLGLVAG
HHHHHHHHCCHHHCCCCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHC
LYPGHPVSRLLMTGSVVGFSLPTFWVGLMLIMAFSVSLGWLPASGRGETAGFLGVQWSWL
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEEHC
TADGLRHLLLPALNLSLFKLSLVLRLTSAGVREVLPQDFVKFARAKGLSPLRVVLAHVLR
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
NTLIPLVTVLGLELGSTIAFAVVTESIFAWPGAGKLILDSINTLDRPLIVSYLIVVVCLF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHH
VSLNLIVDVLYRLLDPRVRAADGMEAAA
HHHHHHHHHHHHHHCCHHHHCCCCCCCC
>Mature Secondary Structure 
TGWLIRRIGQALLVVLVMTVIVFVGLHAIGNPVDILIGQDVDQVDRARIIAELGLDKPL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHCCCCHH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HHHHHHHHHHHHHHCCHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; dipeptides [Periplasm]; H2O [C]

Specific reaction: ATP + dipeptides [Periplasm] + H2O = ADP + phosphate + dipeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]