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The map label for this gene is potC [H]

Identifier: 17546450

GI number: 17546450

Start: 1852043

End: 1852861

Strand: Reverse

Name: potC [H]

Synonym: RSc1731

Alternate gene names: 17546450

Gene position: 1852861-1852043 (Counterclockwise)

Preceding gene: 17546451

Following gene: 17546448

Centisome position: 49.86

GC content: 67.4

Gene sequence:

>819_bases
ATGTTCGCCCCGCACACCTCGCTCATCGAGCGCATCTGGTACTTCGCGCTGCGCGGCCTGGCCGTGCTGACGCTGCTCTA
CCTGGTGCTGCCGGTGCTGGTGATCGTGCCGCTGTCGTTCTCGTCGAGCACCTTCCTCGCCTACCCGATCCCCAGCTACT
CGCTGCGCTGGTACCAGAACCTGGTCAGCTCCGAAGAATGGCGCATGGCCGCCAAGAACAGCTTCATCGTGGCGCCCGCC
GCCACGCTGGTAGCGACCGTGTTCGGCACGCTGGCCGCCATCGGCCTGAACAAGGCGGAATTCCGCGGCAAGGCGCTGCT
GATGGCGATCCTGGTCTCGCCGATGATCGTGCCGGTGGTGGTGGTCGGGGTCGGCATGTACCTGTTCTTCGCGCCGCTCG
GGCTGGCCAACACCTACACCGGCCTGATCCTGGCGCACGCGGCGCTCGGCGTGCCCTTCGTGGTGACGACGGTGCTGGCG
ACGCTGCAGGGCTTCAACCACAACCTCGTGCGCGCCAGCCTGTCGCTGGGCGCCAACCCGGTCATGACGTTCTTCCGCAT
CACCCTGCCGGTGATCGCGCCGGGCGTGATTTCCGGGGCGCTGTTCGCTTTCGCGACCTCGTTCGACGAAGTGGTGGTCA
CACTGTTCCTCGCCGGCGCCGACCAGGTCACGCTGCCGCGCCAGATGTTCACCGGCATCCGCGAGAACATCTCGCCGACC
ATCGCCGCGCTCGCCACCATCCTGATCGTGTTCTCCACCTGCCTGCTGCTGACCTTCGAATGGCTGCGCGGCCGGGCCGC
GGCCAAGGCGGTGGCCTGA

Upstream 100 bases:

>100_bases
GGCGGCCACGCTGGTGCTGTACGGCGTCTACGGCCGCTTCACGCGCGCCAAGGCCAACGCGCGCTGAAGAAAGGAGCCGA
TCATGAAATTCGCCAGGCCG

Downstream 100 bases:

>100_bases
ACGCGCCACCGCCGCCGGCGTCGGGCCGGTCTGAAGGGCCTGAAGGGCCTAGAGGAACATCCCGCCCGACGCCTCGATCC
GCTGCGCGTTGATCCAGCGG

Product: transmembrane ABC transporter protein

Products: Phosphate; putrescine [Cytoplasm]; ADP; spermidine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 272; Mature: 272

Protein sequence:

>272_residues
MFAPHTSLIERIWYFALRGLAVLTLLYLVLPVLVIVPLSFSSSTFLAYPIPSYSLRWYQNLVSSEEWRMAAKNSFIVAPA
ATLVATVFGTLAAIGLNKAEFRGKALLMAILVSPMIVPVVVVGVGMYLFFAPLGLANTYTGLILAHAALGVPFVVTTVLA
TLQGFNHNLVRASLSLGANPVMTFFRITLPVIAPGVISGALFAFATSFDEVVVTLFLAGADQVTLPRQMFTGIRENISPT
IAALATILIVFSTCLLLTFEWLRGRAAAKAVA

Sequences:

>Translated_272_residues
MFAPHTSLIERIWYFALRGLAVLTLLYLVLPVLVIVPLSFSSSTFLAYPIPSYSLRWYQNLVSSEEWRMAAKNSFIVAPA
ATLVATVFGTLAAIGLNKAEFRGKALLMAILVSPMIVPVVVVGVGMYLFFAPLGLANTYTGLILAHAALGVPFVVTTVLA
TLQGFNHNLVRASLSLGANPVMTFFRITLPVIAPGVISGALFAFATSFDEVVVTLFLAGADQVTLPRQMFTGIRENISPT
IAALATILIVFSTCLLLTFEWLRGRAAAKAVA
>Mature_272_residues
MFAPHTSLIERIWYFALRGLAVLTLLYLVLPVLVIVPLSFSSSTFLAYPIPSYSLRWYQNLVSSEEWRMAAKNSFIVAPA
ATLVATVFGTLAAIGLNKAEFRGKALLMAILVSPMIVPVVVVGVGMYLFFAPLGLANTYTGLILAHAALGVPFVVTTVLA
TLQGFNHNLVRASLSLGANPVMTFFRITLPVIAPGVISGALFAFATSFDEVVVTLFLAGADQVTLPRQMFTGIRENISPT
IAALATILIVFSTCLLLTFEWLRGRAAAKAVA

Specific function: Required for the activity of the bacterial periplasmic transport system of putrescine and spermidine [H]

COG id: COG1177

COG function: function code E; ABC-type spermidine/putrescine transport system, permease component II

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787368, Length=219, Percent_Identity=31.9634703196347, Blast_Score=121, Evalue=5e-29,
Organism=Escherichia coli, GI1787081, Length=234, Percent_Identity=31.6239316239316, Blast_Score=102, Evalue=4e-23,
Organism=Escherichia coli, GI1787714, Length=240, Percent_Identity=31.25, Blast_Score=93, Evalue=1e-20,
Organism=Escherichia coli, GI1788764, Length=207, Percent_Identity=28.0193236714976, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1786980, Length=222, Percent_Identity=32.8828828828829, Blast_Score=65, Evalue=7e-12,
Organism=Escherichia coli, GI1787080, Length=132, Percent_Identity=27.2727272727273, Blast_Score=61, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 29212; Mature: 29212

Theoretical pI: Translated: 10.07; Mature: 10.07

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFAPHTSLIERIWYFALRGLAVLTLLYLVLPVLVIVPLSFSSSTFLAYPIPSYSLRWYQN
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCHHHHHHHH
LVSSEEWRMAAKNSFIVAPAATLVATVFGTLAAIGLNKAEFRGKALLMAILVSPMIVPVV
HHCCHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
VVGVGMYLFFAPLGLANTYTGLILAHAALGVPFVVTTVLATLQGFNHNLVRASLSLGANP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCHHHHHHHHCCCHH
VMTFFRITLPVIAPGVISGALFAFATSFDEVVVTLFLAGADQVTLPRQMFTGIRENISPT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCHH
IAALATILIVFSTCLLLTFEWLRGRAAAKAVA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MFAPHTSLIERIWYFALRGLAVLTLLYLVLPVLVIVPLSFSSSTFLAYPIPSYSLRWYQN
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCHHHHHHHH
LVSSEEWRMAAKNSFIVAPAATLVATVFGTLAAIGLNKAEFRGKALLMAILVSPMIVPVV
HHCCHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
VVGVGMYLFFAPLGLANTYTGLILAHAALGVPFVVTTVLATLQGFNHNLVRASLSLGANP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCHHHHHHHHCCCHH
VMTFFRITLPVIAPGVISGALFAFATSFDEVVVTLFLAGADQVTLPRQMFTGIRENISPT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCHH
IAALATILIVFSTCLLLTFEWLRGRAAAKAVA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Putrescine [Periplasm]; H2O; ATP; spermidine [Periplasm] [C]

Specific reaction: ATP + putrescine [Periplasm] + H2O = ADP + phosphate + putrescine [Cytoplasm] ATP + spermidine [Periplasm] + H2O = ADP + phosphate + spermidine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]