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The map label for this gene is qmcA [H]

Identifier: 17546142

GI number: 17546142

Start: 1523975

End: 1524901

Strand: Direct

Name: qmcA [H]

Synonym: RSc1423

Alternate gene names: 17546142

Gene position: 1523975-1524901 (Clockwise)

Preceding gene: 17546141

Following gene: 17546144

Centisome position: 41.01

GC content: 64.94

Gene sequence:

>927_bases
ATGTTCGAGCTGGGGACTCTCGCGCTCATCGTCCTGTTTGCCGCCATCGTACTGATCGCGCAGAGCATCAAGATCGTGCC
GCAGCAGCACGCGTGGATCCTGGAGCGGCTGGGCAAGTACCACGCGACGCTGTCGCCGGGGCTCAATATCGTGCTGCCGT
TCGTCGACCGGGTGGCTTACAAGCACGTGCTCAAGGAGATCCCGCTGGATGTGCCGAGCCAGATCTGCATCACCAAGGAC
AACACGCAGCTGCAGGTCGACGGCATCCTGTACTTCCAGGTGACCGACCCGATGCGCGCTTCGTACGGCTCGAGCAACTT
CGTCATCGCCATCACGCAGCTCGCGCAGACCACGCTGCGCTCGGTGGTCGGCAAGCTGGAGCTGGATAAGACCTTCGAGG
AGCGCGAGTTCATCAACCACAGCGTGGTCAATGCGCTGGACGAGGCGGCCTCCAACTGGGGCGTGAAGGTGCTGCGCTAT
GAGATCAAGGACCTGACGCCGCCCAAGGAGATCCTGCACGCGATGCAGGCGCAGATCACCGCCGAGCGCGAGAAGCGCGC
CCTGATCGCGGCATCTGAAGGCAAGCGCCAGGAGCAGATCAACCTGGCCGCCGGCGCCCGCGAGGCCGCGATCCAGAAAT
CCGAAGGGGAGAAGCAGGCCGCCATCAACCGGGCCCAGGGCGAAGCGGCAGCCATCCTGGCGGTGGCCGAGGCCAACGCG
CAGGCGATCCAGAAGGTCGGTCACGCCATCCGCACCGAAGGCGGCATCGACGCGGTCAACCTGAAGGTGGCCGAGGAATA
CGTGTCGGCGTTCGGCAATCTGGCCAAGCAGGGCAACACGCTGATCGTGCCCGGCAACCTGGGCGACCTGAGCACGATGA
TCGCGTCGGCGCTGCAGATCGTGAAGCAGCAGCGGCCGAACGCGTAG

Upstream 100 bases:

>100_bases
GCCGGCACCGGCCACCGGCGGCGAATTCCGTATCGTCGAGGTGCGCGGCAACGTGCTGGTCGTCGCACCCAAATAGTCTT
TTCCATCGACCGGAGGTTTT

Downstream 100 bases:

>100_bases
CGATGCGATGAGGCGCGAGGCGGGTCAGGCCTTCTCGCGCATGAGCCGCGCCTTCTCGCGCTGCCAGTCGCGGTCCTTCT
CGGTCTCGCGCTTGTCGTAG

Product: transmembrane protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 308; Mature: 308

Protein sequence:

>308_residues
MFELGTLALIVLFAAIVLIAQSIKIVPQQHAWILERLGKYHATLSPGLNIVLPFVDRVAYKHVLKEIPLDVPSQICITKD
NTQLQVDGILYFQVTDPMRASYGSSNFVIAITQLAQTTLRSVVGKLELDKTFEEREFINHSVVNALDEAASNWGVKVLRY
EIKDLTPPKEILHAMQAQITAEREKRALIAASEGKRQEQINLAAGAREAAIQKSEGEKQAAINRAQGEAAAILAVAEANA
QAIQKVGHAIRTEGGIDAVNLKVAEEYVSAFGNLAKQGNTLIVPGNLGDLSTMIASALQIVKQQRPNA

Sequences:

>Translated_308_residues
MFELGTLALIVLFAAIVLIAQSIKIVPQQHAWILERLGKYHATLSPGLNIVLPFVDRVAYKHVLKEIPLDVPSQICITKD
NTQLQVDGILYFQVTDPMRASYGSSNFVIAITQLAQTTLRSVVGKLELDKTFEEREFINHSVVNALDEAASNWGVKVLRY
EIKDLTPPKEILHAMQAQITAEREKRALIAASEGKRQEQINLAAGAREAAIQKSEGEKQAAINRAQGEAAAILAVAEANA
QAIQKVGHAIRTEGGIDAVNLKVAEEYVSAFGNLAKQGNTLIVPGNLGDLSTMIASALQIVKQQRPNA
>Mature_308_residues
MFELGTLALIVLFAAIVLIAQSIKIVPQQHAWILERLGKYHATLSPGLNIVLPFVDRVAYKHVLKEIPLDVPSQICITKD
NTQLQVDGILYFQVTDPMRASYGSSNFVIAITQLAQTTLRSVVGKLELDKTFEEREFINHSVVNALDEAASNWGVKVLRY
EIKDLTPPKEILHAMQAQITAEREKRALIAASEGKRQEQINLAAGAREAAIQKSEGEKQAAINRAQGEAAAILAVAEANA
QAIQKVGHAIRTEGGIDAVNLKVAEEYVSAFGNLAKQGNTLIVPGNLGDLSTMIASALQIVKQQRPNA

Specific function: Unknown

COG id: COG0330

COG function: function code O; Membrane protease subunits, stomatin/prohibitin homologs

Gene ontology:

Cell location: Membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the band 7/mec-2 family [H]

Homologues:

Organism=Homo sapiens, GI7305503, Length=276, Percent_Identity=50.3623188405797, Blast_Score=278, Evalue=6e-75,
Organism=Homo sapiens, GI221316744, Length=197, Percent_Identity=35.5329949238579, Blast_Score=102, Evalue=6e-22,
Organism=Homo sapiens, GI21686995, Length=197, Percent_Identity=35.5329949238579, Blast_Score=101, Evalue=7e-22,
Organism=Homo sapiens, GI38016911, Length=214, Percent_Identity=35.5140186915888, Blast_Score=99, Evalue=6e-21,
Organism=Homo sapiens, GI7657615, Length=186, Percent_Identity=29.0322580645161, Blast_Score=69, Evalue=7e-12,
Organism=Escherichia coli, GI1786697, Length=295, Percent_Identity=41.0169491525424, Blast_Score=229, Evalue=2e-61,
Organism=Escherichia coli, GI1790616, Length=203, Percent_Identity=25.615763546798, Blast_Score=62, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI32564147, Length=281, Percent_Identity=47.6868327402135, Blast_Score=283, Evalue=6e-77,
Organism=Caenorhabditis elegans, GI17569493, Length=221, Percent_Identity=32.579185520362, Blast_Score=109, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI193209764, Length=221, Percent_Identity=32.579185520362, Blast_Score=108, Evalue=5e-24,
Organism=Caenorhabditis elegans, GI17569497, Length=212, Percent_Identity=32.5471698113208, Blast_Score=103, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI71987612, Length=163, Percent_Identity=31.2883435582822, Blast_Score=92, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI25153583, Length=163, Percent_Identity=31.2883435582822, Blast_Score=91, Evalue=7e-19,
Organism=Caenorhabditis elegans, GI71989948, Length=155, Percent_Identity=33.5483870967742, Blast_Score=91, Evalue=7e-19,
Organism=Caenorhabditis elegans, GI71989955, Length=155, Percent_Identity=33.5483870967742, Blast_Score=91, Evalue=7e-19,
Organism=Caenorhabditis elegans, GI193210507, Length=197, Percent_Identity=30.9644670050761, Blast_Score=90, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17570161, Length=197, Percent_Identity=30.9644670050761, Blast_Score=90, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI71987621, Length=166, Percent_Identity=30.7228915662651, Blast_Score=90, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17569499, Length=201, Percent_Identity=32.3383084577114, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI32566490, Length=170, Percent_Identity=31.7647058823529, Blast_Score=86, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17570459, Length=203, Percent_Identity=30.0492610837438, Blast_Score=82, Evalue=3e-16,
Organism=Drosophila melanogaster, GI45550506, Length=282, Percent_Identity=47.8723404255319, Blast_Score=271, Evalue=5e-73,
Organism=Drosophila melanogaster, GI45556022, Length=167, Percent_Identity=35.3293413173653, Blast_Score=106, Evalue=2e-23,
Organism=Drosophila melanogaster, GI18860517, Length=198, Percent_Identity=33.8383838383838, Blast_Score=101, Evalue=6e-22,
Organism=Drosophila melanogaster, GI62484448, Length=169, Percent_Identity=31.9526627218935, Blast_Score=83, Evalue=2e-16,
Organism=Drosophila melanogaster, GI281365664, Length=169, Percent_Identity=31.9526627218935, Blast_Score=83, Evalue=3e-16,
Organism=Drosophila melanogaster, GI62484274, Length=169, Percent_Identity=31.9526627218935, Blast_Score=83, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24657857, Length=169, Percent_Identity=31.9526627218935, Blast_Score=82, Evalue=5e-16,
Organism=Drosophila melanogaster, GI28573263, Length=194, Percent_Identity=26.2886597938144, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI281361631, Length=193, Percent_Identity=25.9067357512953, Blast_Score=79, Evalue=5e-15,
Organism=Drosophila melanogaster, GI281361633, Length=193, Percent_Identity=25.9067357512953, Blast_Score=79, Evalue=5e-15,
Organism=Drosophila melanogaster, GI21356845, Length=187, Percent_Identity=24.5989304812834, Blast_Score=79, Evalue=5e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001107
- InterPro:   IPR018080
- InterPro:   IPR001972 [H]

Pfam domain/function: PF01145 Band_7 [H]

EC number: NA

Molecular weight: Translated: 33488; Mature: 33488

Theoretical pI: Translated: 7.17; Mature: 7.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFELGTLALIVLFAAIVLIAQSIKIVPQQHAWILERLGKYHATLSPGLNIVLPFVDRVAY
CCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
KHVLKEIPLDVPSQICITKDNTQLQVDGILYFQVTDPMRASYGSSNFVIAITQLAQTTLR
HHHHHHCCCCCCCCEEEECCCCEEEEEEEEEEEECCCHHHCCCCCCEEEEHHHHHHHHHH
SVVGKLELDKTFEEREFINHSVVNALDEAASNWGVKVLRYEIKDLTPPKEILHAMQAQIT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHCCCCHHHHHHHHHHHHH
AEREKRALIAASEGKRQEQINLAAGAREAAIQKSEGEKQAAINRAQGEAAAILAVAEANA
HHHHHHEEEEECCCCCHHHHHHHHCCHHHHHHHCCCHHHHHHHHCCCCCEEEEEEHHCCH
QAIQKVGHAIRTEGGIDAVNLKVAEEYVSAFGNLAKQGNTLIVPGNLGDLSTMIASALQI
HHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHHH
VKQQRPNA
HHHHCCCC
>Mature Secondary Structure
MFELGTLALIVLFAAIVLIAQSIKIVPQQHAWILERLGKYHATLSPGLNIVLPFVDRVAY
CCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
KHVLKEIPLDVPSQICITKDNTQLQVDGILYFQVTDPMRASYGSSNFVIAITQLAQTTLR
HHHHHHCCCCCCCCEEEECCCCEEEEEEEEEEEECCCHHHCCCCCCEEEEHHHHHHHHHH
SVVGKLELDKTFEEREFINHSVVNALDEAASNWGVKVLRYEIKDLTPPKEILHAMQAQIT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHCCCCHHHHHHHHHHHHH
AEREKRALIAASEGKRQEQINLAAGAREAAIQKSEGEKQAAINRAQGEAAAILAVAEANA
HHHHHHEEEEECCCCCHHHHHHHHCCHHHHHHHCCCHHHHHHHHCCCCCEEEEEEHHCCH
QAIQKVGHAIRTEGGIDAVNLKVAEEYVSAFGNLAKQGNTLIVPGNLGDLSTMIASALQI
HHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHHH
VKQQRPNA
HHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]