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The map label for this gene is aceB [H]

Identifier: 17546082

GI number: 17546082

Start: 1452102

End: 1453691

Strand: Direct

Name: aceB [H]

Synonym: RSc1363

Alternate gene names: 17546082

Gene position: 1452102-1453691 (Clockwise)

Preceding gene: 17546081

Following gene: 17546083

Centisome position: 39.07

GC content: 67.11

Gene sequence:

>1590_bases
ATGACGACCATGGAGCTGACGCTGCCCCAAGGCATGGAGATCAAGGCCGAGATCCTGCCGGCCTACGAAGACATTCTGAC
CCCCGAGGCGCTGGCCCTCGTCGCCAGGCTGCACCGGGCCTTCGAGCCGCGCCGCCAGCAGCGGCTGGCCGAGCGCGCCG
AGCGCGTCAAGCGCCTCGATGCCGGCGAGCGCCCGGACTTCCTGCCCGAGACCCGGCACATCCGCGAGGGCGACTGGACC
ATCGCCCCGATCCCGCCCGCGCTGGAATGCCGCCGCGTGGAGATCACCGGCCCGGTCGAGGCCAAGATGGTCATCAACGC
GTTCAATTCGGGCGCGGACAGCTACATGACCGACTTCGAGGATTCGAACGCCCCGAGCTGGCACAACCAGATCCAGGGCC
AGGTCAACCTGAAGGCCGCCATCCGCCGCACGCTCACGCTGGAGTCGGGCGGCAAGTCGTACAAGCTCAACGACAAGATC
GCCACGCTGCAGGTGCGCCCGCGCGGCTGGCACCTCGACGAGAAGCACGTGACGGTGGACGGCCAGCGCGTCTCGGGCGG
CATCTTCGACTTCGCGCTGTTCCTCTTCCACAACGCGCGCGAACAGCTCGCGCGCGGCGCCGGTCCGTTCTTCTACCTGC
CGAAGATGGAGAGCCACCTGGAGGCGCGCCTGTGGAACGACGTCTTCATCGCCGCGCAAGACGCGCTCGGCCTGCCGCGG
GGCACCATCAAGGCCACCGTGCTGATCGAGACCATCCTCGCCGCGTTCGAGATGGACGAGATCCTGTATGAGCTGCGCGA
GCACAGCGCGGGCCTGAACGCCGGCCGCTGGGACTACATCTTCTCGTGCATCAAGAAGTTCAAGGTGGACCAGAACTTCT
GCCTGGCCGACCGCGCCCGCGTCACGATGACTTCGCCGTTCATGCGCGCCTACGCGCTGCTGCTGCTCAAGACCTGCCAC
AAGCGCAACGCACCGGCCATGGGCGGCATGAGCGCGCTGATCCCGATCAAGAACGATCCGGAGAAGAACGCCGTCGCCAT
GCAGGGCATCATCAACGACAAGAAGCGCGATGCCACCGACGGCTACGACGGCGGCTGGGTGGCGCACCCGGGCCTGGTCG
AGGCGGCCATGAAGGAATTCGTCGACGTGCTGGGCGATGCCCCCAACCAGATCGGCAAGCAGCGCCCCGACGTGAACGTG
GCCGCCGCCGACCTGCTGAACTTCCAGCCCGAGCAGCCCATCACCGAGGCCGGCCTGCGCATGAACATCAACGTCGGCAT
CCACTACCTGGGCGCCTGGCTGGCCGGCAACGGCTGCGTGCCGATCCACAACCTGATGGAAGACGCGGCCACGGCCGAGA
TCTCGCGCTCGCAGGTGTGGCAGTGGATCCGCTCGCCCAAGGGCACGCTGGAAGACGGCACCAAGGTCACGGCCGAGCTG
GTGCGCAAGCTGATCCCCGAGGAGCTGGCCAAGGTGAAGGCGGACGGCGCGGTGGGCCACTTCGATCGCGCCGCGCAGAT
CTTCGAGCAGATGTCCACGTCGGAGTCGTTCTCGGAATTCCTGACGCTGCCGCTGTACGAAGAACTCTGA

Upstream 100 bases:

>100_bases
GCAGGCCCGGCAATCCATGCGGTAGCAGGACCCCAACCCCGGCATCGGCCGACCAGGCCGGGCCCGTTCAACCCTCACCT
CATCCTCTGGAGATACCACC

Downstream 100 bases:

>100_bases
GCGCCGCTTGCCTGGCGCACGGAACGCCGGCCGGGGTGACCCGGACCGGCGTTTTTCATTTGGGCGACCGCCGCGCCATA
ATGTCGGAAATTTTCCGGAG

Product: malate synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 529; Mature: 528

Protein sequence:

>529_residues
MTTMELTLPQGMEIKAEILPAYEDILTPEALALVARLHRAFEPRRQQRLAERAERVKRLDAGERPDFLPETRHIREGDWT
IAPIPPALECRRVEITGPVEAKMVINAFNSGADSYMTDFEDSNAPSWHNQIQGQVNLKAAIRRTLTLESGGKSYKLNDKI
ATLQVRPRGWHLDEKHVTVDGQRVSGGIFDFALFLFHNAREQLARGAGPFFYLPKMESHLEARLWNDVFIAAQDALGLPR
GTIKATVLIETILAAFEMDEILYELREHSAGLNAGRWDYIFSCIKKFKVDQNFCLADRARVTMTSPFMRAYALLLLKTCH
KRNAPAMGGMSALIPIKNDPEKNAVAMQGIINDKKRDATDGYDGGWVAHPGLVEAAMKEFVDVLGDAPNQIGKQRPDVNV
AAADLLNFQPEQPITEAGLRMNINVGIHYLGAWLAGNGCVPIHNLMEDAATAEISRSQVWQWIRSPKGTLEDGTKVTAEL
VRKLIPEELAKVKADGAVGHFDRAAQIFEQMSTSESFSEFLTLPLYEEL

Sequences:

>Translated_529_residues
MTTMELTLPQGMEIKAEILPAYEDILTPEALALVARLHRAFEPRRQQRLAERAERVKRLDAGERPDFLPETRHIREGDWT
IAPIPPALECRRVEITGPVEAKMVINAFNSGADSYMTDFEDSNAPSWHNQIQGQVNLKAAIRRTLTLESGGKSYKLNDKI
ATLQVRPRGWHLDEKHVTVDGQRVSGGIFDFALFLFHNAREQLARGAGPFFYLPKMESHLEARLWNDVFIAAQDALGLPR
GTIKATVLIETILAAFEMDEILYELREHSAGLNAGRWDYIFSCIKKFKVDQNFCLADRARVTMTSPFMRAYALLLLKTCH
KRNAPAMGGMSALIPIKNDPEKNAVAMQGIINDKKRDATDGYDGGWVAHPGLVEAAMKEFVDVLGDAPNQIGKQRPDVNV
AAADLLNFQPEQPITEAGLRMNINVGIHYLGAWLAGNGCVPIHNLMEDAATAEISRSQVWQWIRSPKGTLEDGTKVTAEL
VRKLIPEELAKVKADGAVGHFDRAAQIFEQMSTSESFSEFLTLPLYEEL
>Mature_528_residues
TTMELTLPQGMEIKAEILPAYEDILTPEALALVARLHRAFEPRRQQRLAERAERVKRLDAGERPDFLPETRHIREGDWTI
APIPPALECRRVEITGPVEAKMVINAFNSGADSYMTDFEDSNAPSWHNQIQGQVNLKAAIRRTLTLESGGKSYKLNDKIA
TLQVRPRGWHLDEKHVTVDGQRVSGGIFDFALFLFHNAREQLARGAGPFFYLPKMESHLEARLWNDVFIAAQDALGLPRG
TIKATVLIETILAAFEMDEILYELREHSAGLNAGRWDYIFSCIKKFKVDQNFCLADRARVTMTSPFMRAYALLLLKTCHK
RNAPAMGGMSALIPIKNDPEKNAVAMQGIINDKKRDATDGYDGGWVAHPGLVEAAMKEFVDVLGDAPNQIGKQRPDVNVA
AADLLNFQPEQPITEAGLRMNINVGIHYLGAWLAGNGCVPIHNLMEDAATAEISRSQVWQWIRSPKGTLEDGTKVTAELV
RKLIPEELAKVKADGAVGHFDRAAQIFEQMSTSESFSEFLTLPLYEEL

Specific function: Glyoxylate bypass; second step. [C]

COG id: COG2225

COG function: function code C; Malate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the malate synthase family [H]

Homologues:

Organism=Escherichia coli, GI1790444, Length=511, Percent_Identity=50.0978473581213, Blast_Score=493, Evalue=1e-140,
Organism=Caenorhabditis elegans, GI17561814, Length=524, Percent_Identity=49.4274809160305, Blast_Score=495, Evalue=1e-140,
Organism=Caenorhabditis elegans, GI71982926, Length=420, Percent_Identity=50.2380952380952, Blast_Score=405, Evalue=1e-113,
Organism=Saccharomyces cerevisiae, GI6324212, Length=515, Percent_Identity=51.2621359223301, Blast_Score=517, Evalue=1e-147,
Organism=Saccharomyces cerevisiae, GI6322222, Length=515, Percent_Identity=50.6796116504854, Blast_Score=513, Evalue=1e-146,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011076
- InterPro:   IPR006252
- InterPro:   IPR001465
- InterPro:   IPR019830 [H]

Pfam domain/function: PF01274 Malate_synthase [H]

EC number: =2.3.3.9 [H]

Molecular weight: Translated: 59068; Mature: 58937

Theoretical pI: Translated: 6.08; Mature: 6.08

Prosite motif: PS00510 MALATE_SYNTHASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTMELTLPQGMEIKAEILPAYEDILTPEALALVARLHRAFEPRRQQRLAERAERVKRLD
CCEEEEECCCCCCCHHHHCCHHHHHCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCC
AGERPDFLPETRHIREGDWTIAPIPPALECRRVEITGPVEAKMVINAFNSGADSYMTDFE
CCCCCCCCCCCCCCCCCCEEEECCCCCCCEEEEEECCCCHHHHHHHHHCCCCHHHHHCCC
DSNAPSWHNQIQGQVNLKAAIRRTLTLESGGKSYKLNDKIATLQVRPRGWHLDEKHVTVD
CCCCCCHHHHCCCCEEHHHHHHHHHEEECCCCEEEECCCEEEEEECCCCCCCCCCEEEEC
GQRVSGGIFDFALFLFHNAREQLARGAGPFFYLPKMESHLEARLWNDVFIAAQDALGLPR
CCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEECCCHHHHHHHHHHHHHEEEEHHHCCCCC
GTIKATVLIETILAAFEMDEILYELREHSAGLNAGRWDYIFSCIKKFKVDQNFCLADRAR
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCEECCCCC
VTMTSPFMRAYALLLLKTCHKRNAPAMGGMSALIPIKNDPEKNAVAMQGIINDKKRDATD
EEECHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCCHHHHHHHHCCCCCCCCC
GYDGGWVAHPGLVEAAMKEFVDVLGDAPNQIGKQRPDVNVAAADLLNFQPEQPITEAGLR
CCCCCEECCCHHHHHHHHHHHHHHCCCHHHHCCCCCCCCHHHHHHHCCCCCCCHHHCCCE
MNINVGIHYLGAWLAGNGCVPIHNLMEDAATAEISRSQVWQWIRSPKGTLEDGTKVTAEL
EEEEECCEEHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHH
VRKLIPEELAKVKADGAVGHFDRAAQIFEQMSTSESFSEFLTLPLYEEL
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHCC
>Mature Secondary Structure 
TTMELTLPQGMEIKAEILPAYEDILTPEALALVARLHRAFEPRRQQRLAERAERVKRLD
CEEEEECCCCCCCHHHHCCHHHHHCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCC
AGERPDFLPETRHIREGDWTIAPIPPALECRRVEITGPVEAKMVINAFNSGADSYMTDFE
CCCCCCCCCCCCCCCCCCEEEECCCCCCCEEEEEECCCCHHHHHHHHHCCCCHHHHHCCC
DSNAPSWHNQIQGQVNLKAAIRRTLTLESGGKSYKLNDKIATLQVRPRGWHLDEKHVTVD
CCCCCCHHHHCCCCEEHHHHHHHHHEEECCCCEEEECCCEEEEEECCCCCCCCCCEEEEC
GQRVSGGIFDFALFLFHNAREQLARGAGPFFYLPKMESHLEARLWNDVFIAAQDALGLPR
CCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEECCCHHHHHHHHHHHHHEEEEHHHCCCCC
GTIKATVLIETILAAFEMDEILYELREHSAGLNAGRWDYIFSCIKKFKVDQNFCLADRAR
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCEECCCCC
VTMTSPFMRAYALLLLKTCHKRNAPAMGGMSALIPIKNDPEKNAVAMQGIINDKKRDATD
EEECHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCCHHHHHHHHCCCCCCCCC
GYDGGWVAHPGLVEAAMKEFVDVLGDAPNQIGKQRPDVNVAAADLLNFQPEQPITEAGLR
CCCCCEECCCHHHHHHHHHHHHHHCCCHHHHCCCCCCCCHHHHHHHCCCCCCCHHHCCCE
MNINVGIHYLGAWLAGNGCVPIHNLMEDAATAEISRSQVWQWIRSPKGTLEDGTKVTAEL
EEEEECCEEHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHH
VRKLIPEELAKVKADGAVGHFDRAAQIFEQMSTSESFSEFLTLPLYEEL
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA