Click here to switch to the map view.

The map label for this gene is fpr [H]

Identifier: 17546024

GI number: 17546024

Start: 1392131

End: 1392907

Strand: Direct

Name: fpr [H]

Synonym: RSc1305

Alternate gene names: 17546024

Gene position: 1392131-1392907 (Clockwise)

Preceding gene: 17546021

Following gene: 17546025

Centisome position: 37.46

GC content: 61.78

Gene sequence:

>777_bases
ATGTCCGCTTTCAATCAAGAGACCGTTCTGAGCGTCCATCACTGGAACGAATCGCTGTTCAGCTTCCGTACCACGCGCGA
CAAAGCCTTGCGCTTCCATAACGGCCACTTTGTCATGCTGGGCCTGGAAGTCGAGGGCAAGCCGCTGATGCGTGCCTACA
GTATCGCCAGCCCCAACTACGAAGAACACCTGGAGTTCTTCAGCATCAAGGTGCAGAACGGCCCGCTGACGTCGCGCCTG
CAGCACCTGAAGGTCGGTGACACCGTGCTGGTCAGCCGCAAGCCGGTCGGCACGCTGGTGCTGGACGACCTGCTGCCCGG
CAAGAACCTCTACCTGTTCGGCACCGGCACCGGCCTGGCGCCGTTCATGAGCATCATCCAGGATCCCGAAACCTACGAGC
GCTTCGAGAAGGTCGTGCTGCTGCACGGCGTGCGCCAGGTCAGCGAACTGGCCTATGCCGATTTCATCACCAGCGAGCTG
CCGAACAACGAATTCTTCGGCGACCAGGTTCGCGAGAAGCTGATCTACTACCCGACCGTCACTCGCGAGCCCTTCCGCAA
CATGGGCCGCCTGACGGATCTGGCCGATAGCGGCAAGCTGTTCGACGACATTGGCCTTGCGCCGCTGGACCCGGCGGTGG
ATCGCGCCATGATCTGCGGCAGCCCCGCCATGCTGGAAGACACCTGCAAGCTGCTGGATGCGCGCGGCTTCAAGATTTCG
TCGCGCATGGGCGAGGCAGGCGACTATGTGATCGAGCGCGCCTTCGTCGAGAAGTAA

Upstream 100 bases:

>100_bases
GCTTATGTGCAATCCATGCAGGCGCGGTAAGAGGGAATCGCATAAAATCAAGGCCTTGACCGCATTTTGCACCGCCGCAA
GGCTGTACCCGAACGTCACC

Downstream 100 bases:

>100_bases
CGCGGGTTTGCTTGCCAACAGGACGCCGGCCCTTGCGCCGGCGTTTTTCATTTGGCGCGAAAGCGCGGCGGGCGGATACA
ATGCGCCGCGTCACAATTTC

Product: ferredoxin--NADP reductase

Products: NA

Alternate protein names: FNR; Protein X [H]

Number of amino acids: Translated: 258; Mature: 257

Protein sequence:

>258_residues
MSAFNQETVLSVHHWNESLFSFRTTRDKALRFHNGHFVMLGLEVEGKPLMRAYSIASPNYEEHLEFFSIKVQNGPLTSRL
QHLKVGDTVLVSRKPVGTLVLDDLLPGKNLYLFGTGTGLAPFMSIIQDPETYERFEKVVLLHGVRQVSELAYADFITSEL
PNNEFFGDQVREKLIYYPTVTREPFRNMGRLTDLADSGKLFDDIGLAPLDPAVDRAMICGSPAMLEDTCKLLDARGFKIS
SRMGEAGDYVIERAFVEK

Sequences:

>Translated_258_residues
MSAFNQETVLSVHHWNESLFSFRTTRDKALRFHNGHFVMLGLEVEGKPLMRAYSIASPNYEEHLEFFSIKVQNGPLTSRL
QHLKVGDTVLVSRKPVGTLVLDDLLPGKNLYLFGTGTGLAPFMSIIQDPETYERFEKVVLLHGVRQVSELAYADFITSEL
PNNEFFGDQVREKLIYYPTVTREPFRNMGRLTDLADSGKLFDDIGLAPLDPAVDRAMICGSPAMLEDTCKLLDARGFKIS
SRMGEAGDYVIERAFVEK
>Mature_257_residues
SAFNQETVLSVHHWNESLFSFRTTRDKALRFHNGHFVMLGLEVEGKPLMRAYSIASPNYEEHLEFFSIKVQNGPLTSRLQ
HLKVGDTVLVSRKPVGTLVLDDLLPGKNLYLFGTGTGLAPFMSIIQDPETYERFEKVVLLHGVRQVSELAYADFITSELP
NNEFFGDQVREKLIYYPTVTREPFRNMGRLTDLADSGKLFDDIGLAPLDPAVDRAMICGSPAMLEDTCKLLDARGFKISS
RMGEAGDYVIERAFVEK

Specific function: Transports Electrons Between Flavodoxin Or Ferredoxin And NADPH. Involved In The Reductive Activation Of Cobalamin- Independent Methionine Synthase, Pyruvate Formate Lyase And Anaerobic Ribonucleotide Reductase. Also Protects Against Superoxide Radicals

COG id: COG1018

COG function: function code C; Flavodoxin reductases (ferredoxin-NADPH reductases) family 1

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding FR-type domain [H]

Homologues:

Organism=Escherichia coli, GI1790359, Length=234, Percent_Identity=34.6153846153846, Blast_Score=130, Evalue=1e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017927
- InterPro:   IPR001709
- InterPro:   IPR008333
- InterPro:   IPR001433
- InterPro:   IPR017938 [H]

Pfam domain/function: PF00970 FAD_binding_6; PF00175 NAD_binding_1 [H]

EC number: =1.18.1.2 [H]

Molecular weight: Translated: 29100; Mature: 28968

Theoretical pI: Translated: 5.63; Mature: 5.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAFNQETVLSVHHWNESLFSFRTTRDKALRFHNGHFVMLGLEVEGKPLMRAYSIASPNY
CCCCCCCCEEEEECCCHHHHHHHHCHHHHEEEECCEEEEEEEEECCCCHHHEEECCCCCH
EEHLEFFSIKVQNGPLTSRLQHLKVGDTVLVSRKPVGTLVLDDLLPGKNLYLFGTGTGLA
HHHEEEEEEEECCCCHHHHHHHHCCCCEEEEECCCCCHHHHHHCCCCCCEEEEECCCCHH
PFMSIIQDPETYERFEKVVLLHGVRQVSELAYADFITSELPNNEFFGDQVREKLIYYPTV
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHEEECCCC
TREPFRNMGRLTDLADSGKLFDDIGLAPLDPAVDRAMICGSPAMLEDTCKLLDARGFKIS
CHHHHHHHHHHHHHCCCCCHHHHCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHCCCCEEH
SRMGEAGDYVIERAFVEK
HHCCCCHHHHHHHHHHCC
>Mature Secondary Structure 
SAFNQETVLSVHHWNESLFSFRTTRDKALRFHNGHFVMLGLEVEGKPLMRAYSIASPNY
CCCCCCCEEEEECCCHHHHHHHHCHHHHEEEECCEEEEEEEEECCCCHHHEEECCCCCH
EEHLEFFSIKVQNGPLTSRLQHLKVGDTVLVSRKPVGTLVLDDLLPGKNLYLFGTGTGLA
HHHEEEEEEEECCCCHHHHHHHHCCCCEEEEECCCCCHHHHHHCCCCCCEEEEECCCCHH
PFMSIIQDPETYERFEKVVLLHGVRQVSELAYADFITSELPNNEFFGDQVREKLIYYPTV
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHEEECCCC
TREPFRNMGRLTDLADSGKLFDDIGLAPLDPAVDRAMICGSPAMLEDTCKLLDARGFKIS
CHHHHHHHHHHHHHCCCCCHHHHCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHCCCCEEH
SRMGEAGDYVIERAFVEK
HHCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7673160; 8034707; 9865948 [H]