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The map label for this gene is pepV [H]

Identifier: 17546021

GI number: 17546021

Start: 1388632

End: 1390359

Strand: Direct

Name: pepV [H]

Synonym: RSc1302

Alternate gene names: 17546021

Gene position: 1388632-1390359 (Clockwise)

Preceding gene: 17546019

Following gene: 17546024

Centisome position: 37.36

GC content: 66.15

Gene sequence:

>1728_bases
ATGCAACGTACCACCTGCTCCGGTCTGTGCGCCTTGGTGTTGGGGCTGCCGCTGGCCATGGCCGCCGGTGCCGCCACGCT
CAAGAAGCCCGAGCTGGATGCGCTGGCCCTGTCAGAGCAGTCGAGCGCCGCATCGTCCGACCTGCCGGATTTTCTAGAGG
CCGCTGCCAAGGCCGATCCCGTGGTCGCCGGCAGTGTTGCCGCCTACCGGCGGCAGTCGCCGCTCACCGGCGATGATCTG
GTCAACATCGGCCGGCTGCTGGGCCTGTACAACCGCCTGCACAACCAGCAGGCGGCGATCGCCTCGATCGAGAAGATGGT
CGCGCTGCCTACGGTGCGCGACGACAGGATTCCGCAGTACGAAAGCCCCGCCATCGTTGCATTCGGCAAGCTGGTTGAAG
GCATGGCACGCGATTTCGGCCTGCGCTACCGCAATGTCGATCACCGGGTCTTCGAAATCACGCTGCCCGGCACCGGTCAG
GACGAATTCGGCATTCTGACGCACGCCGATGTGGTGCCCGCGCGTGCCGAGGAGTGGGTGCTGGACGACGGTACGCGGCT
CGATCCGTTCAAGGTGACGCGTGTTGGCAACCTGCTGTATGGGCGCGGCACCATCGACGACAAGGGGTCGGTTGCCGCCG
CGCTGTATGCGATGAAGACCGTCAAGGACAGCGGTGTGCCGCTCGCGCGGACGATCCGGCTCATGATCGACACCACTGAG
GAAACCGGTGGCGACGGCATGAAGTACTACCGCGAGCGCACCCGGCTGCCCGCGTACAACATCGTGCTCGACAGCAAGTA
TCCCGCCGTGGTGGCCGAGAAGGGCTCGGGTGCGCTGAAAGTGGCGTTCCCCGCGTTGCCGGTGGACATGAGCCGTCTCG
CTATCGTGGCGATGACGGGCGCCGCTTCGGCCAACGCCGTGCCCCAGACCGCCACCGTAACGCTCAAGGGCGGTGACCTG
GGCACAGCGGCTGCCGCATTGGAGGCGAAGCGCGATGCCTTCGTCCGCGGCCTCGCCGCGCAAGGCGCGTTCTCCATTGA
TGTCACGCGCAGCGCAGACAGTGTCATCGTCAAGGTGACCGGTGCGTCCGCGCACGGCTCACGGCCGGAGGAGGGCGTCA
ACCCGCTGCCGCGCCTGGTGCTGTTCCTGCGCGCGGCCGGCCTCGACCTGGCCGACAACGCTTATGCCCATGCCGTGCGC
TACCTGACCGATCTGTACGGGACGGACTACCTTGGCAATCCGATGGGTGTCGCCTACAAGGACGACTTCATGGGGCCGCT
GACGATGTCGCCCAATGCGATCGGCGACAGGAACGGCCGCGTCGAAGTGGCCGTCAACGTGCGCATGCCACGCGGCAAGA
CGCCCGATGCCCTGCGCGGTGAGATTGCCGGCAGGATCAACGCCTGGGCCGGCGCCAGCCGCATCGCTGTGGAGATCAGC
CACGATCAGGGCAACTGGATGGCGCGCGACCCGAAGGGCGCATGGCTTGCAACGCTACTGAACATCTATGGCGAGACCAC
CGGCCTGGATGCCAGGCCGGTGCCGACGGCTGGCAGCACCGCGGCCAAGCTGATGCCCAATGCCATCAACTTCGGGCCGG
CCATGCCGGGTAAGAAGCACACGGCGCACAACGCCAAGGAGTACAAGGAAGTGCCGGATCTCGACCTGGACATGCAGATG
TTCACCGAGATGCTGGTCCGTATCGGCAGCCTGCCGGCGATGCAATAA

Upstream 100 bases:

>100_bases
TCAAGCATAGCCTGCCGTCCCGCATTGCCGCTCCGAGGATGCGCGGGCTGGGCATCCCGCCTATGATGCTGCCTTCGCTC
GCTTTCAGGGAACCGTTTCG

Downstream 100 bases:

>100_bases
GCGTCGGCCCGGCGCCACGAGGTCATCTGTGCAAGTCGTTCACTGCTGAACGCGCAGGCACCGGGCAAGCGACACCATAG
GTACGTGGGTGGCAGGGGCG

Product: hypothetical protein

Products: NA

Alternate protein names: Beta-Ala-His dipeptidase; Peptidase V [H]

Number of amino acids: Translated: 575; Mature: 575

Protein sequence:

>575_residues
MQRTTCSGLCALVLGLPLAMAAGAATLKKPELDALALSEQSSAASSDLPDFLEAAAKADPVVAGSVAAYRRQSPLTGDDL
VNIGRLLGLYNRLHNQQAAIASIEKMVALPTVRDDRIPQYESPAIVAFGKLVEGMARDFGLRYRNVDHRVFEITLPGTGQ
DEFGILTHADVVPARAEEWVLDDGTRLDPFKVTRVGNLLYGRGTIDDKGSVAAALYAMKTVKDSGVPLARTIRLMIDTTE
ETGGDGMKYYRERTRLPAYNIVLDSKYPAVVAEKGSGALKVAFPALPVDMSRLAIVAMTGAASANAVPQTATVTLKGGDL
GTAAAALEAKRDAFVRGLAAQGAFSIDVTRSADSVIVKVTGASAHGSRPEEGVNPLPRLVLFLRAAGLDLADNAYAHAVR
YLTDLYGTDYLGNPMGVAYKDDFMGPLTMSPNAIGDRNGRVEVAVNVRMPRGKTPDALRGEIAGRINAWAGASRIAVEIS
HDQGNWMARDPKGAWLATLLNIYGETTGLDARPVPTAGSTAAKLMPNAINFGPAMPGKKHTAHNAKEYKEVPDLDLDMQM
FTEMLVRIGSLPAMQ

Sequences:

>Translated_575_residues
MQRTTCSGLCALVLGLPLAMAAGAATLKKPELDALALSEQSSAASSDLPDFLEAAAKADPVVAGSVAAYRRQSPLTGDDL
VNIGRLLGLYNRLHNQQAAIASIEKMVALPTVRDDRIPQYESPAIVAFGKLVEGMARDFGLRYRNVDHRVFEITLPGTGQ
DEFGILTHADVVPARAEEWVLDDGTRLDPFKVTRVGNLLYGRGTIDDKGSVAAALYAMKTVKDSGVPLARTIRLMIDTTE
ETGGDGMKYYRERTRLPAYNIVLDSKYPAVVAEKGSGALKVAFPALPVDMSRLAIVAMTGAASANAVPQTATVTLKGGDL
GTAAAALEAKRDAFVRGLAAQGAFSIDVTRSADSVIVKVTGASAHGSRPEEGVNPLPRLVLFLRAAGLDLADNAYAHAVR
YLTDLYGTDYLGNPMGVAYKDDFMGPLTMSPNAIGDRNGRVEVAVNVRMPRGKTPDALRGEIAGRINAWAGASRIAVEIS
HDQGNWMARDPKGAWLATLLNIYGETTGLDARPVPTAGSTAAKLMPNAINFGPAMPGKKHTAHNAKEYKEVPDLDLDMQM
FTEMLVRIGSLPAMQ
>Mature_575_residues
MQRTTCSGLCALVLGLPLAMAAGAATLKKPELDALALSEQSSAASSDLPDFLEAAAKADPVVAGSVAAYRRQSPLTGDDL
VNIGRLLGLYNRLHNQQAAIASIEKMVALPTVRDDRIPQYESPAIVAFGKLVEGMARDFGLRYRNVDHRVFEITLPGTGQ
DEFGILTHADVVPARAEEWVLDDGTRLDPFKVTRVGNLLYGRGTIDDKGSVAAALYAMKTVKDSGVPLARTIRLMIDTTE
ETGGDGMKYYRERTRLPAYNIVLDSKYPAVVAEKGSGALKVAFPALPVDMSRLAIVAMTGAASANAVPQTATVTLKGGDL
GTAAAALEAKRDAFVRGLAAQGAFSIDVTRSADSVIVKVTGASAHGSRPEEGVNPLPRLVLFLRAAGLDLADNAYAHAVR
YLTDLYGTDYLGNPMGVAYKDDFMGPLTMSPNAIGDRNGRVEVAVNVRMPRGKTPDALRGEIAGRINAWAGASRIAVEIS
HDQGNWMARDPKGAWLATLLNIYGETTGLDARPVPTAGSTAAKLMPNAINFGPAMPGKKHTAHNAKEYKEVPDLDLDMQM
FTEMLVRIGSLPAMQ

Specific function: Is a relatively unspecific dipeptidase cleaving a variety of dipeptides, notably those with an N-terminal beta-Ala or D-Ala residue, e.g. carnosine (beta-Ala-His). To a lesser extent, also shows aminopeptidase activity, since it is able to catalyze the re

COG id: COG0624

COG function: function code E; Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M20A family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001261
- InterPro:   IPR011291
- InterPro:   IPR010964
- InterPro:   IPR002933
- InterPro:   IPR011650 [H]

Pfam domain/function: PF01546 Peptidase_M20 [H]

EC number: 3.4.13.3

Molecular weight: Translated: 61157; Mature: 61157

Theoretical pI: Translated: 6.97; Mature: 6.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQRTTCSGLCALVLGLPLAMAAGAATLKKPELDALALSEQSSAASSDLPDFLEAAAKADP
CCCCCHHHHHHHHHHHHHHHHCCCHHCCCCCCCCEEECCCCCCCCCCCHHHHHHHHCCCC
VVAGSVAAYRRQSPLTGDDLVNIGRLLGLYNRLHNQQAAIASIEKMVALPTVRDDRIPQY
CEECHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCCCCCCCCC
ESPAIVAFGKLVEGMARDFGLRYRNVDHRVFEITLPGTGQDEFGILTHADVVPARAEEWV
CCCHHHHHHHHHHHHHHHHCCEEECCCCEEEEEEECCCCCCCCCEEEECCCCCCCCCCEE
LDDGTRLDPFKVTRVGNLLYGRGTIDDKGSVAAALYAMKTVKDSGVPLARTIRLMIDTTE
ECCCCCCCCEEEEEECCEEEECCCCCCCCCHHHHHHHHHHHCCCCCCHHHEEEEEEECCC
ETGGDGMKYYRERTRLPAYNIVLDSKYPAVVAEKGSGALKVAFPALPVDMSRLAIVAMTG
CCCCCHHHHHHHHHCCCEEEEEECCCCCEEEEECCCCEEEEEECCCCCCCCCEEEEEEEC
AASANAVPQTATVTLKGGDLGTAAAALEAKRDAFVRGLAAQGAFSIDVTRSADSVIVKVT
CCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCEEEEEEE
GASAHGSRPEEGVNPLPRLVLFLRAAGLDLADNAYAHAVRYLTDLYGTDYLGNPMGVAYK
CCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCEEC
DDFMGPLTMSPNAIGDRNGRVEVAVNVRMPRGKTPDALRGEIAGRINAWAGASRIAVEIS
CCCCCCEECCCCCCCCCCCEEEEEEEEECCCCCCCHHHHHHHHCCEECCCCCCEEEEEEE
HDQGNWMARDPKGAWLATLLNIYGETTGLDARPVPTAGSTAAKLMPNAINFGPAMPGKKH
CCCCCEEEECCCCHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHCCCCCCCCCCCCCCCC
TAHNAKEYKEVPDLDLDMQMFTEMLVRIGSLPAMQ
CCCCHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MQRTTCSGLCALVLGLPLAMAAGAATLKKPELDALALSEQSSAASSDLPDFLEAAAKADP
CCCCCHHHHHHHHHHHHHHHHCCCHHCCCCCCCCEEECCCCCCCCCCCHHHHHHHHCCCC
VVAGSVAAYRRQSPLTGDDLVNIGRLLGLYNRLHNQQAAIASIEKMVALPTVRDDRIPQY
CEECHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCCCCCCCCC
ESPAIVAFGKLVEGMARDFGLRYRNVDHRVFEITLPGTGQDEFGILTHADVVPARAEEWV
CCCHHHHHHHHHHHHHHHHCCEEECCCCEEEEEEECCCCCCCCCEEEECCCCCCCCCCEE
LDDGTRLDPFKVTRVGNLLYGRGTIDDKGSVAAALYAMKTVKDSGVPLARTIRLMIDTTE
ECCCCCCCCEEEEEECCEEEECCCCCCCCCHHHHHHHHHHHCCCCCCHHHEEEEEEECCC
ETGGDGMKYYRERTRLPAYNIVLDSKYPAVVAEKGSGALKVAFPALPVDMSRLAIVAMTG
CCCCCHHHHHHHHHCCCEEEEEECCCCCEEEEECCCCEEEEEECCCCCCCCCEEEEEEEC
AASANAVPQTATVTLKGGDLGTAAAALEAKRDAFVRGLAAQGAFSIDVTRSADSVIVKVT
CCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCEEEEEEE
GASAHGSRPEEGVNPLPRLVLFLRAAGLDLADNAYAHAVRYLTDLYGTDYLGNPMGVAYK
CCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCEEC
DDFMGPLTMSPNAIGDRNGRVEVAVNVRMPRGKTPDALRGEIAGRINAWAGASRIAVEIS
CCCCCCEECCCCCCCCCCCEEEEEEEEECCCCCCCHHHHHHHHCCEECCCCCCEEEEEEE
HDQGNWMARDPKGAWLATLLNIYGETTGLDARPVPTAGSTAAKLMPNAINFGPAMPGKKH
CCCCCEEEECCCCHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHCCCCCCCCCCCCCCCC
TAHNAKEYKEVPDLDLDMQMFTEMLVRIGSLPAMQ
CCCCHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7528082 [H]