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The map label for this gene is iolB [H]

Identifier: 17545956

GI number: 17545956

Start: 1309821

End: 1310636

Strand: Reverse

Name: iolB [H]

Synonym: RSc1237

Alternate gene names: 17545956

Gene position: 1310636-1309821 (Counterclockwise)

Preceding gene: 17545957

Following gene: 17545955

Centisome position: 35.27

GC content: 68.38

Gene sequence:

>816_bases
ATGACGATCTCTCCATTGCTGGTCAAGGCGTTGCCGAAGCGCGAGATATGCAATGTCACGCCGGAATCCGCCGGCTGGAA
GCACGTCGGCTTTCGCGCGCTGCGCCTGGCGGCCGGCGACCACGAAACGGTGGAAACCGGTACGCGCGAGCTGTGCGTGG
TCGTGCTGACCGGCACGATCCGCGCCGAGGTCGACGGCACCACGTTTGAGGGCCTGGGCAAGCGCGACAGCGTGTTCGAC
GACGTGTCGCCCGATGCCCTGTACGCGCCCGGCGGCAAGACCGTCACGATCACCGCCACGCGCGACGCGGAAGTCGCGCT
CTGCACCGCGCCCTGCATCAGCGGCGACAAGGTCGTGCACCGCCTCGACGGCGAGCGGATGCGCCGCACCGTGCGCGGCA
GTGGCAGCAACACCCGCTACGTCTGCGACATCCTGATGGGCGACAACCCGGCGGCCGACCGGCTGCTCGTGGTGGAGGTG
GTGACCCCGGCCGGCCATTCCAGCAGCTATCCGCCGCACAAGCACGACAGCGCCGCCGAGCCCGGCGAAACCGTGCTGGA
GGAAACCTACTACCACCGGCTCAACCCGCCCCAGGGCTTTGCGTTCCAGCGCGTCTACACCGATGACCGCAGCCTGGACG
AAGCCTGCGCCGTCGAGAATCACGACGTCGTCATGGTGCCGCGCGGCTACCACCCGGTGGTCGCGCCGCACGGCTACAGC
CTGTATTACCTGAACGTGATGGCCGGTCCGAGCCGGGCGTGGGCCTTCCGGAACGACCCGGTCCATGAGTGGATGCTGCG
TCCGCCTTCGGACTAA

Upstream 100 bases:

>100_bases
GCTATCAATACGCGAAGAAGGGCTACGAAACGCTGCGCGCGCTGGTCGACCGGCTGGGCGCCTGACCTGCGCCGCCACCG
CTTTGCGAAAGGAGCTTTCC

Downstream 100 bases:

>100_bases
GCCTCGTATCGCTCCCGCACCAACATCAGCACCCCCTTCTTCCCACGCACGGCAACCGTGCAAGCGTGGCGAGCGAGATC
GCGCCCGCGATCTGCCATCG

Product: myo-inositol catabolism protein

Products: NA

Alternate protein names: 5DG isomerase [H]

Number of amino acids: Translated: 271; Mature: 270

Protein sequence:

>271_residues
MTISPLLVKALPKREICNVTPESAGWKHVGFRALRLAAGDHETVETGTRELCVVVLTGTIRAEVDGTTFEGLGKRDSVFD
DVSPDALYAPGGKTVTITATRDAEVALCTAPCISGDKVVHRLDGERMRRTVRGSGSNTRYVCDILMGDNPAADRLLVVEV
VTPAGHSSSYPPHKHDSAAEPGETVLEETYYHRLNPPQGFAFQRVYTDDRSLDEACAVENHDVVMVPRGYHPVVAPHGYS
LYYLNVMAGPSRAWAFRNDPVHEWMLRPPSD

Sequences:

>Translated_271_residues
MTISPLLVKALPKREICNVTPESAGWKHVGFRALRLAAGDHETVETGTRELCVVVLTGTIRAEVDGTTFEGLGKRDSVFD
DVSPDALYAPGGKTVTITATRDAEVALCTAPCISGDKVVHRLDGERMRRTVRGSGSNTRYVCDILMGDNPAADRLLVVEV
VTPAGHSSSYPPHKHDSAAEPGETVLEETYYHRLNPPQGFAFQRVYTDDRSLDEACAVENHDVVMVPRGYHPVVAPHGYS
LYYLNVMAGPSRAWAFRNDPVHEWMLRPPSD
>Mature_270_residues
TISPLLVKALPKREICNVTPESAGWKHVGFRALRLAAGDHETVETGTRELCVVVLTGTIRAEVDGTTFEGLGKRDSVFDD
VSPDALYAPGGKTVTITATRDAEVALCTAPCISGDKVVHRLDGERMRRTVRGSGSNTRYVCDILMGDNPAADRLLVVEVV
TPAGHSSSYPPHKHDSAAEPGETVLEETYYHRLNPPQGFAFQRVYTDDRSLDEACAVENHDVVMVPRGYHPVVAPHGYSL
YYLNVMAGPSRAWAFRNDPVHEWMLRPPSD

Specific function: Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate) [H]

COG id: COG3718

COG function: function code G; Uncharacterized enzyme involved in inositol metabolism

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the isomerase iolB family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011051
- InterPro:   IPR021120
- InterPro:   IPR014710 [H]

Pfam domain/function: PF04962 KduI [H]

EC number: NA

Molecular weight: Translated: 29711; Mature: 29580

Theoretical pI: Translated: 6.12; Mature: 6.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTISPLLVKALPKREICNVTPESAGWKHVGFRALRLAAGDHETVETGTRELCVVVLTGTI
CCCCHHHHHHCCCHHHCCCCCCCCCCCHHCEEEEEEECCCCHHHHCCCCEEEEEEEECEE
RAEVDGTTFEGLGKRDSVFDDVSPDALYAPGGKTVTITATRDAEVALCTAPCISGDKVVH
EEEECCCCCCCCCCCCCCCCCCCCCEEECCCCCEEEEEEECCCCEEEEECCCCCCCHHEE
RLDGERMRRTVRGSGSNTRYVCDILMGDNPAADRLLVVEVVTPAGHSSSYPPHKHDSAAE
CCCCHHHHHHHCCCCCCCEEEEEEEECCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCC
PGETVLEETYYHRLNPPQGFAFQRVYTDDRSLDEACAVENHDVVMVPRGYHPVVAPHGYS
CHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCHHHHCCCCCCEEEECCCCCCEECCCCCE
LYYLNVMAGPSRAWAFRNDPVHEWMLRPPSD
EEEEEEECCCCCEEEECCCCHHHHEECCCCC
>Mature Secondary Structure 
TISPLLVKALPKREICNVTPESAGWKHVGFRALRLAAGDHETVETGTRELCVVVLTGTI
CCCHHHHHHCCCHHHCCCCCCCCCCCHHCEEEEEEECCCCHHHHCCCCEEEEEEEECEE
RAEVDGTTFEGLGKRDSVFDDVSPDALYAPGGKTVTITATRDAEVALCTAPCISGDKVVH
EEEECCCCCCCCCCCCCCCCCCCCCEEECCCCCEEEEEEECCCCEEEEECCCCCCCHHEE
RLDGERMRRTVRGSGSNTRYVCDILMGDNPAADRLLVVEVVTPAGHSSSYPPHKHDSAAE
CCCCHHHHHHHCCCCCCCEEEEEEEECCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCC
PGETVLEETYYHRLNPPQGFAFQRVYTDDRSLDEACAVENHDVVMVPRGYHPVVAPHGYS
CHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCHHHHCCCCCCEEEECCCCCCEECCCCCE
LYYLNVMAGPSRAWAFRNDPVHEWMLRPPSD
EEEEEEECCCCCEEEECCCCHHHHEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA