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The map label for this gene is hflC [H]

Identifier: 17545942

GI number: 17545942

Start: 1293153

End: 1294067

Strand: Direct

Name: hflC [H]

Synonym: RSc1223

Alternate gene names: 17545942

Gene position: 1293153-1294067 (Clockwise)

Preceding gene: 17545941

Following gene: 17545943

Centisome position: 34.8

GC content: 65.36

Gene sequence:

>915_bases
ATGAATCGTCTGATTTCCGCCCTCGTGGCGCTGGTGATTGCCCTGGCGGTCCTGTCGTCGGTGGTGTTCGTGGTGGACCA
GCGGCAGTACGCCGTGGTGTTCGCCTTCGGTGAGATCAAGCAGGTCATCAAGGAGCCGGGGCTGCACTTCAAGCTGCCGC
CGCCGCTGCAGAACGTGATCTTCATGGACAAGCGCCTGATGACCATCGACGTGGCTGGTGCCGACCGCTTCATCACGGCC
GAGAAGAAGAACCTGCTGGTCGACTGGTTCGTCAAATGGCGGGTTTCCGATCCGCGCCTGTTCTACGTGAGCTTCAAGGG
CGACAACCGCCTCGCGCAGGACAGCATGACGCAGAAGATCAACTCCATCGCTCGCGACGAATTCGCGCGCCGCACCGTCT
CCGACGTGGTCTCGACCGACCGCGAGGCGGTGATGCAGAGCATCCTCAAGGGCGTGCAGGAATACGGCAGGTCGGTTGGC
GTCGACATCATCGACGTGCGTCTCAAGCGCGTCGATCTGCTGGCCAGCGTGACCGAGTCTGTCTACCGCCGCATGGAGGC
CGAGCGAAAGCGCGTGGCCAACGAACTGCGCTCGACCGGCGCCGCCGAAGGCGAGAAGATCCGCGCCGACGCCGACCGCC
AGCGCGAGGTGGTGCTGGCCGATGCCTACCGCGAAGCCCAGAAGATCAAGGGTGAGGGCGATGCCCGCGCCGCCGACATC
TATGCCGACGCGTTCGGCCGCGATCCGCAGTTTGCCGCGTTCTGGCGCAGCATGGAGGCGTATCGCGCGTCGTTCCGCGA
CCGCAAGGACGTGATGGTGCTGCAGCCCGGCAGCGATTTCTTCAAGTTCATGCGCGGCCCCAACGGCGGCGGCCAGTCCG
TCGCACCGGCTGCCCAGGCTGGGCGCCATCGCTAG

Upstream 100 bases:

>100_bases
CCTACGCCCTCCAATCCGTCGTCGATGAGCGACGCCGACTCGCGCTCGCGCGAGGCGCTGCGTAATCGCGAACGCGATTC
CCGTTAAGAGGAGAGGGCTC

Downstream 100 bases:

>100_bases
TAGAATTGCGTCGCTGATCGACTCGCGGCGAACAGACCCCGGCTTGCCGGGGTTTTGTTCGTCCGCAAACCGCGTTTCAT
GGTTCATGGAAGATTCACTC

Product: serine protease transmembrane protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 304; Mature: 304

Protein sequence:

>304_residues
MNRLISALVALVIALAVLSSVVFVVDQRQYAVVFAFGEIKQVIKEPGLHFKLPPPLQNVIFMDKRLMTIDVAGADRFITA
EKKNLLVDWFVKWRVSDPRLFYVSFKGDNRLAQDSMTQKINSIARDEFARRTVSDVVSTDREAVMQSILKGVQEYGRSVG
VDIIDVRLKRVDLLASVTESVYRRMEAERKRVANELRSTGAAEGEKIRADADRQREVVLADAYREAQKIKGEGDARAADI
YADAFGRDPQFAAFWRSMEAYRASFRDRKDVMVLQPGSDFFKFMRGPNGGGQSVAPAAQAGRHR

Sequences:

>Translated_304_residues
MNRLISALVALVIALAVLSSVVFVVDQRQYAVVFAFGEIKQVIKEPGLHFKLPPPLQNVIFMDKRLMTIDVAGADRFITA
EKKNLLVDWFVKWRVSDPRLFYVSFKGDNRLAQDSMTQKINSIARDEFARRTVSDVVSTDREAVMQSILKGVQEYGRSVG
VDIIDVRLKRVDLLASVTESVYRRMEAERKRVANELRSTGAAEGEKIRADADRQREVVLADAYREAQKIKGEGDARAADI
YADAFGRDPQFAAFWRSMEAYRASFRDRKDVMVLQPGSDFFKFMRGPNGGGQSVAPAAQAGRHR
>Mature_304_residues
MNRLISALVALVIALAVLSSVVFVVDQRQYAVVFAFGEIKQVIKEPGLHFKLPPPLQNVIFMDKRLMTIDVAGADRFITA
EKKNLLVDWFVKWRVSDPRLFYVSFKGDNRLAQDSMTQKINSIARDEFARRTVSDVVSTDREAVMQSILKGVQEYGRSVG
VDIIDVRLKRVDLLASVTESVYRRMEAERKRVANELRSTGAAEGEKIRADADRQREVVLADAYREAQKIKGEGDARAADI
YADAFGRDPQFAAFWRSMEAYRASFRDRKDVMVLQPGSDFFKFMRGPNGGGQSVAPAAQAGRHR

Specific function: HflC and HflK could encode or regulate a protease [H]

COG id: COG0330

COG function: function code O; Membrane protease subunits, stomatin/prohibitin homologs

Gene ontology:

Cell location: Membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the band 7/mec-2 family. HflC subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790617, Length=313, Percent_Identity=36.4217252396166, Blast_Score=190, Evalue=8e-50,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001107
- InterPro:   IPR010200
- InterPro:   IPR001972 [H]

Pfam domain/function: PF01145 Band_7 [H]

EC number: 3.4.-.-

Molecular weight: Translated: 34241; Mature: 34241

Theoretical pI: Translated: 10.25; Mature: 10.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRLISALVALVIALAVLSSVVFVVDQRQYAVVFAFGEIKQVIKEPGLHFKLPPPLQNVI
CHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEHHHHHHHHHCCCCEEECCCCHHHHH
FMDKRLMTIDVAGADRFITAEKKNLLVDWFVKWRVSDPRLFYVSFKGDNRLAQDSMTQKI
HHCCEEEEEEECCCCCEEECCCCCCEEEEEEEEEECCCEEEEEEECCCCCHHHHHHHHHH
NSIARDEFARRTVSDVVSTDREAVMQSILKGVQEYGRSVGVDIIDVRLKRVDLLASVTES
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
VYRRMEAERKRVANELRSTGAAEGEKIRADADRQREVVLADAYREAQKIKGEGDARAADI
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHH
YADAFGRDPQFAAFWRSMEAYRASFRDRKDVMVLQPGSDFFKFMRGPNGGGQSVAPAAQA
HHHHCCCCCHHHHHHHHHHHHHHHHCCCCCEEEECCCHHHHHHHCCCCCCCCCCCCHHHC
GRHR
CCCC
>Mature Secondary Structure
MNRLISALVALVIALAVLSSVVFVVDQRQYAVVFAFGEIKQVIKEPGLHFKLPPPLQNVI
CHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEHHHHHHHHHCCCCEEECCCCHHHHH
FMDKRLMTIDVAGADRFITAEKKNLLVDWFVKWRVSDPRLFYVSFKGDNRLAQDSMTQKI
HHCCEEEEEEECCCCCEEECCCCCCEEEEEEEEEECCCEEEEEEECCCCCHHHHHHHHHH
NSIARDEFARRTVSDVVSTDREAVMQSILKGVQEYGRSVGVDIIDVRLKRVDLLASVTES
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
VYRRMEAERKRVANELRSTGAAEGEKIRADADRQREVVLADAYREAQKIKGEGDARAADI
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHH
YADAFGRDPQFAAFWRSMEAYRASFRDRKDVMVLQPGSDFFKFMRGPNGGGQSVAPAAQA
HHHHCCCCCHHHHHHHHHHHHHHHHCCCCCEEEECCCHHHHHHHCCCCCCCCCCCCHHHC
GRHR
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]