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The map label for this gene is hflK [H]

Identifier: 17545941

GI number: 17545941

Start: 1291796

End: 1293139

Strand: Direct

Name: hflK [H]

Synonym: RSc1222

Alternate gene names: 17545941

Gene position: 1291796-1293139 (Clockwise)

Preceding gene: 17545940

Following gene: 17545942

Centisome position: 34.76

GC content: 67.49

Gene sequence:

>1344_bases
TTGCCCACATCGGCGCGAGGCCTGTGGCACCGCCTGCGCGTGCTGCTTTCGCTGAACGACCCGCGTTGGGGGCGTGGCGA
TGACAACAACGCCGAGCGTGAAGACAAGGACGATCCGAAGCGCCAAAGCAAGCCGCCCCAGGATGGCCCGCCCGACCTGG
ACGAGCTGTGGCGCGACTTCAACCGCCGTCTGAACAATCTGTTCGGCCGCAAGGAAGGCGGCAACGGTAATGGCCCGACG
CCGCTGCGTCCCGGCAACGGCCGTGCGGGCTCCGGCCTGGGCGTCGGCGTGCTGCTGGCGGTGCTGGCGGTGCTGTGGCT
GGCCAGCGGCTTCTTCATCGTGCAGGAAGGCCAGACCGGCGTGATCCTGCAGTTCGGCCGCTTCAAGTATCAGGCGACCC
CGGGCATCAACTGGCGCTTGCCGTATCCGATCGAGACGCACGAGATCGTCAACCTGTCGGGCGTGCGCACGCTGGAGATC
GGCCGCACCACGCAGATCAAGGACACCAACCTGAAGGATTCGTCGATGCTCACGCAGGACGAGAACATCGTCGACGTGCG
TTTCTCGGTCCAGTACAACATCGCCGATCCGGTCGAATACCTGTTCTACAACCGTACCGATCAGCGCGGCGACGAGGAGC
TCGTGACGCAGGCGGCGGAGACGTCGGTGCGCGAGATCGTCGGCCGCAACAAGATGGACGCCGTGCTGTACGAAGGGCGC
GATGCGGTCGGCCGCAACCTGGCGGAATCGATCCAGCGCATCCTGTCGGCGTACAAGACCGGCATCCGCATCCTGAGCGT
CAACGTGCAGAGCGTGCAGCCGCCCGAGCAGGTGCAGTCGGCCTTCGATGACGTGACCAAGGCCGGGCAGGATCGCGAGC
GCGCGATCTCCGAGGGCCAGGCCTATGCCAACGACGTGGTGCCGCGCGCCAAGGGCACGGCCGCGCGCCTGGGCGAGGAG
GCGCAGGGCTACAAGGCCCGCGTGGTCGCCCGCGCGGAAGGCGATGCCGCCCGCTTCGCGTCGGTGCAGCGCGAATACGC
GAAGGCGCCGCAGGTCACGCGCGATCGCATTTACCTGGAAACGATGCAGGACATCTACGCCAACGCGACCAAGGTGCTGG
TCGACCAGAGCGGCAACGGCAACCTGCTGTACCTGCCGCTCGACAAGCTGATCGCCCAGTCGCAGACCGGCGACGCGGCG
CGTACGCAGCCGGTGCCCGGCGCGTCGCCGCAGGACAGCGGCTCGGCGCAGGGCATGCCTACGCCCTCCAATCCGTCGTC
GATGAGCGACGCCGACTCGCGCTCGCGCGAGGCGCTGCGTAATCGCGAACGCGATTCCCGTTAA

Upstream 100 bases:

>100_bases
GAGACTGATAGAATCCGCTGTTACATCCTTTGCCGTCAGACAATCAGGACAAGCCCAACCGCTCATGCCCGAGATTTCGA
CCCCGTCATCTTCCCCGGCT

Downstream 100 bases:

>100_bases
GAGGAGAGGGCTCATGAATCGTCTGATTTCCGCCCTCGTGGCGCTGGTGATTGCCCTGGCGGTCCTGTCGTCGGTGGTGT
TCGTGGTGGACCAGCGGCAG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 447; Mature: 446

Protein sequence:

>447_residues
MPTSARGLWHRLRVLLSLNDPRWGRGDDNNAEREDKDDPKRQSKPPQDGPPDLDELWRDFNRRLNNLFGRKEGGNGNGPT
PLRPGNGRAGSGLGVGVLLAVLAVLWLASGFFIVQEGQTGVILQFGRFKYQATPGINWRLPYPIETHEIVNLSGVRTLEI
GRTTQIKDTNLKDSSMLTQDENIVDVRFSVQYNIADPVEYLFYNRTDQRGDEELVTQAAETSVREIVGRNKMDAVLYEGR
DAVGRNLAESIQRILSAYKTGIRILSVNVQSVQPPEQVQSAFDDVTKAGQDRERAISEGQAYANDVVPRAKGTAARLGEE
AQGYKARVVARAEGDAARFASVQREYAKAPQVTRDRIYLETMQDIYANATKVLVDQSGNGNLLYLPLDKLIAQSQTGDAA
RTQPVPGASPQDSGSAQGMPTPSNPSSMSDADSRSREALRNRERDSR

Sequences:

>Translated_447_residues
MPTSARGLWHRLRVLLSLNDPRWGRGDDNNAEREDKDDPKRQSKPPQDGPPDLDELWRDFNRRLNNLFGRKEGGNGNGPT
PLRPGNGRAGSGLGVGVLLAVLAVLWLASGFFIVQEGQTGVILQFGRFKYQATPGINWRLPYPIETHEIVNLSGVRTLEI
GRTTQIKDTNLKDSSMLTQDENIVDVRFSVQYNIADPVEYLFYNRTDQRGDEELVTQAAETSVREIVGRNKMDAVLYEGR
DAVGRNLAESIQRILSAYKTGIRILSVNVQSVQPPEQVQSAFDDVTKAGQDRERAISEGQAYANDVVPRAKGTAARLGEE
AQGYKARVVARAEGDAARFASVQREYAKAPQVTRDRIYLETMQDIYANATKVLVDQSGNGNLLYLPLDKLIAQSQTGDAA
RTQPVPGASPQDSGSAQGMPTPSNPSSMSDADSRSREALRNRERDSR
>Mature_446_residues
PTSARGLWHRLRVLLSLNDPRWGRGDDNNAEREDKDDPKRQSKPPQDGPPDLDELWRDFNRRLNNLFGRKEGGNGNGPTP
LRPGNGRAGSGLGVGVLLAVLAVLWLASGFFIVQEGQTGVILQFGRFKYQATPGINWRLPYPIETHEIVNLSGVRTLEIG
RTTQIKDTNLKDSSMLTQDENIVDVRFSVQYNIADPVEYLFYNRTDQRGDEELVTQAAETSVREIVGRNKMDAVLYEGRD
AVGRNLAESIQRILSAYKTGIRILSVNVQSVQPPEQVQSAFDDVTKAGQDRERAISEGQAYANDVVPRAKGTAARLGEEA
QGYKARVVARAEGDAARFASVQREYAKAPQVTRDRIYLETMQDIYANATKVLVDQSGNGNLLYLPLDKLIAQSQTGDAAR
TQPVPGASPQDSGSAQGMPTPSNPSSMSDADSRSREALRNRERDSR

Specific function: HflC and HflK could encode or regulate a protease [H]

COG id: COG0330

COG function: function code O; Membrane protease subunits, stomatin/prohibitin homologs

Gene ontology:

Cell location: Membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the band 7/mec-2 family. HflK subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790616, Length=283, Percent_Identity=38.1625441696113, Blast_Score=215, Evalue=5e-57,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001107
- InterPro:   IPR010201
- InterPro:   IPR020980
- InterPro:   IPR001972 [H]

Pfam domain/function: PF01145 Band_7; PF12221 HflK_N [H]

EC number: NA

Molecular weight: Translated: 49366; Mature: 49234

Theoretical pI: Translated: 6.61; Mature: 6.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPTSARGLWHRLRVLLSLNDPRWGRGDDNNAEREDKDDPKRQSKPPQDGPPDLDELWRDF
CCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCCCCHHHHHHHH
NRRLNNLFGRKEGGNGNGPTPLRPGNGRAGSGLGVGVLLAVLAVLWLASGFFIVQEGQTG
HHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCEEEECCCCC
VILQFGRFKYQATPGINWRLPYPIETHEIVNLSGVRTLEIGRTTQIKDTNLKDSSMLTQD
EEEEECCEEEEECCCCCCEECCCCCCCCEEECCCCEEEECCCCCEECCCCCCCCHHCCCC
ENIVDVRFSVQYNIADPVEYLFYNRTDQRGDEELVTQAAETSVREIVGRNKMDAVLYEGR
CCEEEEEEEEEECCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHCCCC
DAVGRNLAESIQRILSAYKTGIRILSVNVQSVQPPEQVQSAFDDVTKAGQDRERAISEGQ
HHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCHHHHHHHHHHHHHCCCHHHHHHHHCH
AYANDVVPRAKGTAARLGEEAQGYKARVVARAEGDAARFASVQREYAKAPQVTRDRIYLE
HHHHHCCCCCCCHHHHCCCHHCCCEEEEEEECCCCHHHHHHHHHHHHHCCCHHHHHHHHH
TMQDIYANATKVLVDQSGNGNLLYLPLDKLIAQSQTGDAARTQPVPGASPQDSGSAQGMP
HHHHHHCCCEEEEEECCCCCCEEEEEHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCC
TPSNPSSMSDADSRSREALRNRERDSR
CCCCCCCCCHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
PTSARGLWHRLRVLLSLNDPRWGRGDDNNAEREDKDDPKRQSKPPQDGPPDLDELWRDF
CCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCCCCHHHHHHHH
NRRLNNLFGRKEGGNGNGPTPLRPGNGRAGSGLGVGVLLAVLAVLWLASGFFIVQEGQTG
HHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCEEEECCCCC
VILQFGRFKYQATPGINWRLPYPIETHEIVNLSGVRTLEIGRTTQIKDTNLKDSSMLTQD
EEEEECCEEEEECCCCCCEECCCCCCCCEEECCCCEEEECCCCCEECCCCCCCCHHCCCC
ENIVDVRFSVQYNIADPVEYLFYNRTDQRGDEELVTQAAETSVREIVGRNKMDAVLYEGR
CCEEEEEEEEEECCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHCCCC
DAVGRNLAESIQRILSAYKTGIRILSVNVQSVQPPEQVQSAFDDVTKAGQDRERAISEGQ
HHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCHHHHHHHHHHHHHCCCHHHHHHHHCH
AYANDVVPRAKGTAARLGEEAQGYKARVVARAEGDAARFASVQREYAKAPQVTRDRIYLE
HHHHHCCCCCCCHHHHCCCHHCCCEEEEEEECCCCHHHHHHHHHHHHHCCCHHHHHHHHH
TMQDIYANATKVLVDQSGNGNLLYLPLDKLIAQSQTGDAARTQPVPGASPQDSGSAQGMP
HHHHHHCCCEEEEEECCCCCCEEEEEHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCC
TPSNPSSMSDADSRSREALRNRERDSR
CCCCCCCCCHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]