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The map label for this gene is nemR [H]

Identifier: 17545920

GI number: 17545920

Start: 1269808

End: 1270437

Strand: Direct

Name: nemR [H]

Synonym: RSc1201

Alternate gene names: 17545920

Gene position: 1269808-1270437 (Clockwise)

Preceding gene: 17545919

Following gene: 17545921

Centisome position: 34.17

GC content: 67.78

Gene sequence:

>630_bases
ATGAGCAAGCACCCCGAACCCGTCACCGCCGAGGGCACCGAAGCCCGGCACGACACCCGCGACCGCATCCTGGACGCGGG
GGCCGAGCTGATCCTCGGACGGGGCTTCTCGGCGGTCGGCCTGGCCGAGATCCTTGGCCGCGCGCAGGTGCCCAAGGGCT
CGTTCTATTACTACTTCGATTCCAAGGAAAACTTCGGCGTCGCATTGCTGGAGCGGTATTTTCAGGATTACGAGGCCGGC
GTCGTTAGCCTGTTCAACGACACGCGCATGACGGCGCGTGAACGGCTGATTCGCTACTTCGCCGCCTGGATCGACCTGCA
CGAGCGCAGCGCCTGCGAGGTTACCTGCCTGGCGGTCAAGCTGTCGGGCGAGGTCTCCGATCTGTCGGAGCCGATGCGCA
AGGTGCTGTCGGCCGGCATGACGCGCATGGTCGAGCGTATCGCCGCGGCCGTGGAGGCGGGCGTGGCGGACGGTTCGCTC
GCGCCGGTGGCCGATCCGCGCGGGCTGGCCGAAGGGCTGTACGCGATGTGGATGGGCGGGGCGCTGCTGGCCAAGGCGCA
CCGGTCGACCGCGCCGTTCCACGGCTGCGTCGCACAGACCGAAGGGTTGCTGGCCAAGCCGAATCATTGA

Upstream 100 bases:

>100_bases
AGCCGAAGACCGGCGAAACCGAAAAACTGTAAGTCACATCGACCCTGCCACGCACAGGGTCATGCAACTAGACGGTCGGT
CTACTATAATCCGTTCCATC

Downstream 100 bases:

>100_bases
GCGCACATGACACCATGCCGGCGAGGCACGTTCCTCGCCTTTCTTTTGGTCCGGTTATAGACGACCGGTCTAATACTTGA
ACTGGATGTTCCAGTCTCTC

Product: transcription regulator protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 209; Mature: 208

Protein sequence:

>209_residues
MSKHPEPVTAEGTEARHDTRDRILDAGAELILGRGFSAVGLAEILGRAQVPKGSFYYYFDSKENFGVALLERYFQDYEAG
VVSLFNDTRMTARERLIRYFAAWIDLHERSACEVTCLAVKLSGEVSDLSEPMRKVLSAGMTRMVERIAAAVEAGVADGSL
APVADPRGLAEGLYAMWMGGALLAKAHRSTAPFHGCVAQTEGLLAKPNH

Sequences:

>Translated_209_residues
MSKHPEPVTAEGTEARHDTRDRILDAGAELILGRGFSAVGLAEILGRAQVPKGSFYYYFDSKENFGVALLERYFQDYEAG
VVSLFNDTRMTARERLIRYFAAWIDLHERSACEVTCLAVKLSGEVSDLSEPMRKVLSAGMTRMVERIAAAVEAGVADGSL
APVADPRGLAEGLYAMWMGGALLAKAHRSTAPFHGCVAQTEGLLAKPNH
>Mature_208_residues
SKHPEPVTAEGTEARHDTRDRILDAGAELILGRGFSAVGLAEILGRAQVPKGSFYYYFDSKENFGVALLERYFQDYEAGV
VSLFNDTRMTARERLIRYFAAWIDLHERSACEVTCLAVKLSGEVSDLSEPMRKVLSAGMTRMVERIAAAVEAGVADGSLA
PVADPRGLAEGLYAMWMGGALLAKAHRSTAPFHGCVAQTEGLLAKPNH

Specific function: Represses the transcription of the nemRA operon by binding to the nemR box [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH tetR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI145693141, Length=207, Percent_Identity=38.1642512077295, Blast_Score=150, Evalue=4e-38,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009057
- InterPro:   IPR015893
- InterPro:   IPR011075
- InterPro:   IPR001647 [H]

Pfam domain/function: PF00440 TetR_N [H]

EC number: NA

Molecular weight: Translated: 22720; Mature: 22589

Theoretical pI: Translated: 6.25; Mature: 6.25

Prosite motif: PS50977 HTH_TETR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKHPEPVTAEGTEARHDTRDRILDAGAELILGRGFSAVGLAEILGRAQVPKGSFYYYFD
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCEEEEEC
SKENFGVALLERYFQDYEAGVVSLFNDTRMTARERLIRYFAAWIDLHERSACEVTCLAVK
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEE
LSGEVSDLSEPMRKVLSAGMTRMVERIAAAVEAGVADGSLAPVADPRGLAEGLYAMWMGG
ECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHH
ALLAKAHRSTAPFHGCVAQTEGLLAKPNH
HHHHHHHHCCCCHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
SKHPEPVTAEGTEARHDTRDRILDAGAELILGRGFSAVGLAEILGRAQVPKGSFYYYFD
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCEEEEEC
SKENFGVALLERYFQDYEAGVVSLFNDTRMTARERLIRYFAAWIDLHERSACEVTCLAVK
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEE
LSGEVSDLSEPMRKVLSAGMTRMVERIAAAVEAGVADGSLAPVADPRGLAEGLYAMWMGG
ECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHH
ALLAKAHRSTAPFHGCVAQTEGLLAKPNH
HHHHHHHHCCCCHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]