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The map label for this gene is ywbI [H]

Identifier: 17545915

GI number: 17545915

Start: 1264744

End: 1265664

Strand: Direct

Name: ywbI [H]

Synonym: RSc1196

Alternate gene names: 17545915

Gene position: 1264744-1265664 (Clockwise)

Preceding gene: 17545913

Following gene: 17545916

Centisome position: 34.03

GC content: 71.77

Gene sequence:

>921_bases
ATGAATCTCGCTCGCTTCGATCTCGTCACGCTTGGCCTGTTTGTTGCGGTGGCCAGGCTGGGCAGCATCTCGGCCGGGGC
GCGCCAGTCGCACCTGGCGGTGGCGGCGGCGAGCAAGCGCATTTCGGACCTGGAAGCGGCCGTGGGCGCGCCGCTGCTGT
ACCGGCACGCCGCCGGCGTCGAACTGACCGAAGCCGGCCAGGCGTGCTTCCGCCATGCGGTGGGCATCCTGCAGGATGTC
GAGCGCATGGCGGGCGCGCTGTCCGACTTCGCGGCGGGCACGCGCGGGCTGGTACGGGTGTGGGCCAACACCTCGTCGAT
CACGCAGTTCCTGGCCGACGACCTGGCCGCCTTCATGCTGGCCAATCCGGCCATCCGCATCGCGCTGGAGGAACAGGACA
GCGGCGACATCGTTGCCGCGCTGCGCGAGAACCGGGCCGACCTCGGCATCTTCGCCGCCGGCACGCCATGCGAGGGCCTG
CAGTCGTTCGACTATCGCGAGGACGACCTCGCCCTGGTCACGCCGCGCGGCCACCCGCTGGCGGGCCGCAAGCAGGCGCG
CTTTGCCGAGGCCGCCGATTTCGATTTCGTCAGCCTGCCCCCGGGCACCTCGCTGGCCGCGCAGTTGCTGGAAGAAAGCC
AGCGCCTGGGCCGGCCGTTGCGTCTGCGCATCCAGGTGCGCAGCTTCGAGGCGGTCTGCCGCATGGTGGCCTCGGGGCTC
GGGGTGGGCGTGCTGCCGCGCATTGCCGCGCAGGCGCATGTCTCCAGCCTGCCGGGCGCGGGCCTCGCGCTGGTGCCGCT
GGACGACGACTGGGCGCATCGCCGCCTGCTGGTGGGCGTACGCGACCCCGATGCGCTGACCAGCTCGGCGCGCCTGCTGA
TGACGCATCTGCTCGGCAATCCCGCCGCGCTCCGACTCTGA

Upstream 100 bases:

>100_bases
CGCCATGGTAAACGGGGCGCAACGATTTGCCCGTGAAAACCGCGCCGATCGGGTCGGCCCTGTTGCATTTTTTCCCAACC
TTGCCGGATGGCTTCCAACG

Downstream 100 bases:

>100_bases
CCTTCTCCCACTTTCTCTGGCGCTTGATCACCATGCCGACACAGGTTTTGCAGGACATCCGCGTGCTCGAACTCGGGCAA
CTGATCGCCGGGCCGTTTGC

Product: DNA-binding transcriptional regulatory transcription regulator protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 306; Mature: 306

Protein sequence:

>306_residues
MNLARFDLVTLGLFVAVARLGSISAGARQSHLAVAAASKRISDLEAAVGAPLLYRHAAGVELTEAGQACFRHAVGILQDV
ERMAGALSDFAAGTRGLVRVWANTSSITQFLADDLAAFMLANPAIRIALEEQDSGDIVAALRENRADLGIFAAGTPCEGL
QSFDYREDDLALVTPRGHPLAGRKQARFAEAADFDFVSLPPGTSLAAQLLEESQRLGRPLRLRIQVRSFEAVCRMVASGL
GVGVLPRIAAQAHVSSLPGAGLALVPLDDDWAHRRLLVGVRDPDALTSSARLLMTHLLGNPAALRL

Sequences:

>Translated_306_residues
MNLARFDLVTLGLFVAVARLGSISAGARQSHLAVAAASKRISDLEAAVGAPLLYRHAAGVELTEAGQACFRHAVGILQDV
ERMAGALSDFAAGTRGLVRVWANTSSITQFLADDLAAFMLANPAIRIALEEQDSGDIVAALRENRADLGIFAAGTPCEGL
QSFDYREDDLALVTPRGHPLAGRKQARFAEAADFDFVSLPPGTSLAAQLLEESQRLGRPLRLRIQVRSFEAVCRMVASGL
GVGVLPRIAAQAHVSSLPGAGLALVPLDDDWAHRRLLVGVRDPDALTSSARLLMTHLLGNPAALRL
>Mature_306_residues
MNLARFDLVTLGLFVAVARLGSISAGARQSHLAVAAASKRISDLEAAVGAPLLYRHAAGVELTEAGQACFRHAVGILQDV
ERMAGALSDFAAGTRGLVRVWANTSSITQFLADDLAAFMLANPAIRIALEEQDSGDIVAALRENRADLGIFAAGTPCEGL
QSFDYREDDLALVTPRGHPLAGRKQARFAEAADFDFVSLPPGTSLAAQLLEESQRLGRPLRLRIQVRSFEAVCRMVASGL
GVGVLPRIAAQAHVSSLPGAGLALVPLDDDWAHRRLLVGVRDPDALTSSARLLMTHLLGNPAALRL

Specific function: Positive Regulatory Protein For The Cyn Operon. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI157672245, Length=243, Percent_Identity=27.5720164609054, Blast_Score=86, Evalue=4e-18,
Organism=Escherichia coli, GI145693105, Length=289, Percent_Identity=24.5674740484429, Blast_Score=82, Evalue=6e-17,
Organism=Escherichia coli, GI1787601, Length=261, Percent_Identity=23.7547892720307, Blast_Score=75, Evalue=6e-15,
Organism=Escherichia coli, GI1787879, Length=244, Percent_Identity=27.0491803278689, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1788297, Length=265, Percent_Identity=27.9245283018868, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1788887, Length=247, Percent_Identity=25.9109311740891, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI2367136, Length=251, Percent_Identity=23.9043824701195, Blast_Score=65, Evalue=8e-12,
Organism=Escherichia coli, GI1786401, Length=145, Percent_Identity=31.7241379310345, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 32410; Mature: 32410

Theoretical pI: Translated: 6.88; Mature: 6.88

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLARFDLVTLGLFVAVARLGSISAGARQSHLAVAAASKRISDLEAAVGAPLLYRHAAGV
CCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCC
ELTEAGQACFRHAVGILQDVERMAGALSDFAAGTRGLVRVWANTSSITQFLADDLAAFML
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHEEEECCHHHHHHHHHHHHHHHHH
ANPAIRIALEEQDSGDIVAALRENRADLGIFAAGTPCEGLQSFDYREDDLALVTPRGHPL
CCCEEEEEEECCCCCCEEHHHHHCCCCEEEEECCCCCCHHHCCCCCCCCEEEECCCCCCC
AGRKQARFAEAADFDFVSLPPGTSLAAQLLEESQRLGRPLRLRIQVRSFEAVCRMVASGL
CCCHHHHHHHHCCCCEEECCCCHHHHHHHHHHHHHCCCCEEEEEEEHHHHHHHHHHHHCC
GVGVLPRIAAQAHVSSLPGAGLALVPLDDDWAHRRLLVGVRDPDALTSSARLLMTHLLGN
CCCHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHCC
PAALRL
CCCCCC
>Mature Secondary Structure
MNLARFDLVTLGLFVAVARLGSISAGARQSHLAVAAASKRISDLEAAVGAPLLYRHAAGV
CCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCC
ELTEAGQACFRHAVGILQDVERMAGALSDFAAGTRGLVRVWANTSSITQFLADDLAAFML
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHEEEECCHHHHHHHHHHHHHHHHH
ANPAIRIALEEQDSGDIVAALRENRADLGIFAAGTPCEGLQSFDYREDDLALVTPRGHPL
CCCEEEEEEECCCCCCEEHHHHHCCCCEEEEECCCCCCHHHCCCCCCCCEEEECCCCCCC
AGRKQARFAEAADFDFVSLPPGTSLAAQLLEESQRLGRPLRLRIQVRSFEAVCRMVASGL
CCCHHHHHHHHCCCCEEECCCCHHHHHHHHHHHHHCCCCEEEEEEEHHHHHHHHHHHHCC
GVGVLPRIAAQAHVSSLPGAGLALVPLDDDWAHRRLLVGVRDPDALTSSARLLMTHLLGN
CCCHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHCC
PAALRL
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7934828; 9384377 [H]