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The map label for this gene is lolC [H]

Identifier: 17545836

GI number: 17545836

Start: 1173762

End: 1175012

Strand: Direct

Name: lolC [H]

Synonym: RSc1117

Alternate gene names: 17545836

Gene position: 1173762-1175012 (Clockwise)

Preceding gene: 17545832

Following gene: 17545837

Centisome position: 31.58

GC content: 64.99

Gene sequence:

>1251_bases
TTGAAATTTCCATACGAATGGCAGATCGGCTGGCGTTACACGCGCGCGAGCAAGCGCGCCAGCCGCAACAGCTTCATTTC
CTTCATCTCGCTCATCTCCATGCTCGGCATCGCGCTGGGCGTGGCCGCGCTGATCGTCGTGCTGTCGGTCATGAACGGCT
TCCAGAAGGAGGTGCGCGACCGCATGCTGTCGGTGCTGTCGCACATCGAGATCATGGCGCCGGGCAGCCTGCCCGACTGG
CAGCGCACCGCGAATGAGGCGATGCAGAACAAGGAGGTCGTGGGCGCGGCGCCGTACGTGGGCGCGCAGGCCATGATCAC
GCGCGACGACGCGGTGCGCGGCGTGCTGCTGCGCGGCGTGTCGCCGGCCGACGAGCCCAAGGTGTCGGACATCGCCAAGG
ATTTCAAGTCGGGCACCATCGACGATCTCCGGCCCGGCGAATTCGGCATCGCGCTGGGCGCCGAGATGGCGCGCGGCCTG
GGCGTGCGCCAGGGCGACAAGGTCACGCTGGTGGCCCCGCAGGGCACCATCACGCCGGCGGGCGTGCTGCCGCGCCTGAA
GCAGTTCACCGTGATCGGCACGTTCGAATCCGGCCACTACGAGTTCGACAGCTCGCTCGCCCTCATCAACATGGAGGATG
CCGAGCGGCTGTTCCGGCTGACCGGCCCGACCGGCGTGCGCCTGAAGCTGGTCGATATGCAGCGCGCGCCGCAGGTGGCC
GAGGCGCTGTCGCGCACGCTGACCGGCGAGCTGTACATCCGCGACTGGTCGCGCCAGAACAAGAACTGGTTCGCCGCCGT
GCAGACCGAGAAGAAGATGATGTTCATCATCCTCACGCTGATCATCGCGGTGGCGGCGTTCAACCTGGTCTCCACGCTGG
TGATGACGGTGACCGACAAGCAGGCCGACATCGCCATCCTGCGCACGATGGGCGCGCAGCCGGGCTCCATCATGAAAATT
TTTATTGTGCAGGGTGTGGCGATCGGCTTTATTGGTACCCTTTTGGGCGTGCTGTTCGGCACGCTGATCGCTTACAACAT
CGACGTGATCGTGCCGGCCATCGAGCATCTCTTCGGCGTGCAATTCCTGCCCAAGGACATCTACTTCATCAGCGAACTGC
CCTCGGACCCCCGCGTGAACGACATCGCAACCATCGGCCTCATTTCCTTCGTGCTCGCCTCGGTGGCGACGCTGTATCCG
AGCTGGCACGCCTCGCGCGTGAACCCGGCGGAGGCGCTGCGCTATGAGTGA

Upstream 100 bases:

>100_bases
GGACAATTAGGGTGAGTTCGGGAATCATGGCCCCGAGATTGTAAACTTCCGGCTGGCTGGCGAGGGCGCCGGCTACATCA
CATCCAATGGGGACGCCCCT

Downstream 100 bases:

>100_bases
GGCCGTGATGACCGCCAACGAGACCACGCACCGCGCCGAGTGGGGTGATACCGCGGTGCTGCAGGCGCAGGGACTGGTCA
AGGCGTTCAGGCAGGGGGGG

Product: lipoprotein releasing system transmembrane

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 416; Mature: 416

Protein sequence:

>416_residues
MKFPYEWQIGWRYTRASKRASRNSFISFISLISMLGIALGVAALIVVLSVMNGFQKEVRDRMLSVLSHIEIMAPGSLPDW
QRTANEAMQNKEVVGAAPYVGAQAMITRDDAVRGVLLRGVSPADEPKVSDIAKDFKSGTIDDLRPGEFGIALGAEMARGL
GVRQGDKVTLVAPQGTITPAGVLPRLKQFTVIGTFESGHYEFDSSLALINMEDAERLFRLTGPTGVRLKLVDMQRAPQVA
EALSRTLTGELYIRDWSRQNKNWFAAVQTEKKMMFIILTLIIAVAAFNLVSTLVMTVTDKQADIAILRTMGAQPGSIMKI
FIVQGVAIGFIGTLLGVLFGTLIAYNIDVIVPAIEHLFGVQFLPKDIYFISELPSDPRVNDIATIGLISFVLASVATLYP
SWHASRVNPAEALRYE

Sequences:

>Translated_416_residues
MKFPYEWQIGWRYTRASKRASRNSFISFISLISMLGIALGVAALIVVLSVMNGFQKEVRDRMLSVLSHIEIMAPGSLPDW
QRTANEAMQNKEVVGAAPYVGAQAMITRDDAVRGVLLRGVSPADEPKVSDIAKDFKSGTIDDLRPGEFGIALGAEMARGL
GVRQGDKVTLVAPQGTITPAGVLPRLKQFTVIGTFESGHYEFDSSLALINMEDAERLFRLTGPTGVRLKLVDMQRAPQVA
EALSRTLTGELYIRDWSRQNKNWFAAVQTEKKMMFIILTLIIAVAAFNLVSTLVMTVTDKQADIAILRTMGAQPGSIMKI
FIVQGVAIGFIGTLLGVLFGTLIAYNIDVIVPAIEHLFGVQFLPKDIYFISELPSDPRVNDIATIGLISFVLASVATLYP
SWHASRVNPAEALRYE
>Mature_416_residues
MKFPYEWQIGWRYTRASKRASRNSFISFISLISMLGIALGVAALIVVLSVMNGFQKEVRDRMLSVLSHIEIMAPGSLPDW
QRTANEAMQNKEVVGAAPYVGAQAMITRDDAVRGVLLRGVSPADEPKVSDIAKDFKSGTIDDLRPGEFGIALGAEMARGL
GVRQGDKVTLVAPQGTITPAGVLPRLKQFTVIGTFESGHYEFDSSLALINMEDAERLFRLTGPTGVRLKLVDMQRAPQVA
EALSRTLTGELYIRDWSRQNKNWFAAVQTEKKMMFIILTLIIAVAAFNLVSTLVMTVTDKQADIAILRTMGAQPGSIMKI
FIVQGVAIGFIGTLLGVLFGTLIAYNIDVIVPAIEHLFGVQFLPKDIYFISELPSDPRVNDIATIGLISFVLASVATLYP
SWHASRVNPAEALRYE

Specific function: Part of an ATP-dependent transport system responsible for the release of lipoproteins targeted to the outer membrane from the inner membrane. Such a release is dependent of the sorting-signal (absence of an Asp at position 2 of the mature lipoprotein) and

COG id: COG4591

COG function: function code M; ABC-type transport system, involved in lipoprotein release, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787362, Length=416, Percent_Identity=33.8942307692308, Blast_Score=226, Evalue=3e-60,
Organism=Escherichia coli, GI1787360, Length=420, Percent_Identity=35.2380952380952, Blast_Score=201, Evalue=9e-53,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003838
- InterPro:   IPR011925 [H]

Pfam domain/function: PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 45608; Mature: 45608

Theoretical pI: Translated: 9.14; Mature: 9.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFPYEWQIGWRYTRASKRASRNSFISFISLISMLGIALGVAALIVVLSVMNGFQKEVRD
CCCCEEEECCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RMLSVLSHIEIMAPGSLPDWQRTANEAMQNKEVVGAAPYVGAQAMITRDDAVRGVLLRGV
HHHHHHHHHEEECCCCCCHHHHHHHHHHHCCCCCCCCCCCCCEEEEECHHHHHHHHHCCC
SPADEPKVSDIAKDFKSGTIDDLRPGEFGIALGAEMARGLGVRQGDKVTLVAPQGTITPA
CCCCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCHH
GVLPRLKQFTVIGTFESGHYEFDSSLALINMEDAERLFRLTGPTGVRLKLVDMQRAPQVA
HHHHHHHHEEEEEEECCCCEEECCCEEEEEHHHHHHHHHCCCCCCCEEEEECCCCCHHHH
EALSRTLTGELYIRDWSRQNKNWFAAVQTEKKMMFIILTLIIAVAAFNLVSTLVMTVTDK
HHHHHHHCCEEEEEECCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
QADIAILRTMGAQPGSIMKIFIVQGVAIGFIGTLLGVLFGTLIAYNIDVIVPAIEHLFGV
CHHHHHHHHCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
QFLPKDIYFISELPSDPRVNDIATIGLISFVLASVATLYPSWHASRVNPAEALRYE
HHCCCHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHCCC
>Mature Secondary Structure
MKFPYEWQIGWRYTRASKRASRNSFISFISLISMLGIALGVAALIVVLSVMNGFQKEVRD
CCCCEEEECCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RMLSVLSHIEIMAPGSLPDWQRTANEAMQNKEVVGAAPYVGAQAMITRDDAVRGVLLRGV
HHHHHHHHHEEECCCCCCHHHHHHHHHHHCCCCCCCCCCCCCEEEEECHHHHHHHHHCCC
SPADEPKVSDIAKDFKSGTIDDLRPGEFGIALGAEMARGLGVRQGDKVTLVAPQGTITPA
CCCCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCHH
GVLPRLKQFTVIGTFESGHYEFDSSLALINMEDAERLFRLTGPTGVRLKLVDMQRAPQVA
HHHHHHHHEEEEEEECCCCEEECCCEEEEEHHHHHHHHHCCCCCCCEEEEECCCCCHHHH
EALSRTLTGELYIRDWSRQNKNWFAAVQTEKKMMFIILTLIIAVAAFNLVSTLVMTVTDK
HHHHHHHCCEEEEEECCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
QADIAILRTMGAQPGSIMKIFIVQGVAIGFIGTLLGVLFGTLIAYNIDVIVPAIEHLFGV
CHHHHHHHHCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
QFLPKDIYFISELPSDPRVNDIATIGLISFVLASVATLYPSWHASRVNPAEALRYE
HHCCCHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10761919 [H]