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The map label for this gene is nagK [C]

Identifier: 17545805

GI number: 17545805

Start: 1144215

End: 1144913

Strand: Reverse

Name: nagK [C]

Synonym: RSc1086

Alternate gene names: 17545805

Gene position: 1144913-1144215 (Counterclockwise)

Preceding gene: 17545806

Following gene: 17545804

Centisome position: 30.81

GC content: 70.1

Gene sequence:

>699_bases
ATGACCTACGTCTTCACGCCCCCCGCCCTCACCGCCATTCCCGTTGCCGGCAGCAGCGAACAGTTCGCCGTGCGCCGCGT
CTACTGCGTCGGCCGCAACTATGCCGCGCATGCCCGCGAGATGGGCTTCGACCCCGACCGCGAGCCGCCGTTCTTCTTCT
GCAAGCCGGCCGATGCCATCGTGCCGGTGGCCGACGGCCAGACGCTGGCGCTGCCCTATCCCACGCAGACGCAGAACTAC
CACTACGAGGCCGAGCTGGTGGCCGTGATCGGCAAGGCCGGCGCCGACATCGCGGTGGACGATGCGCTCGACCACGTGTG
GGGCTACGCCGTCGGCCTCGACATGACCCGCCGCGACCTGCAGATGAAGATGCGCGAGATGGGCCGCCCGTGGGAGATCG
GCAAGGCCTTCGACGTCTCCGCGCCGGTCGGGCCGATCCGCCGCGCCAGCGACATCGGCCACCCGCGGCAGGCCGGCATC
TGGCTGACCGTCAACGGCGAGGCGAAGCAGCGCAGCGACGTCTCGCACCTGATCTGGTCGGTGGCCGAGACGGTGGCCTG
CCTGTCGCAGTTCTTCCGCCTGGAACCGGGCGACGTGATCTTCACCGGCACCCCGGAGGGCGTGGGTGCGGTCAAGCCCG
GCGACACCATCGCGACGGGGGTCGACGGCCTGGGTGAACTGAACGTCCGCATCGCCTGA

Upstream 100 bases:

>100_bases
GACGCGGCGTGCCGGCCGCCGCCGGCCCCGCTCACCCTTCCGATCCGATCCGATCCGATCCGATCCGATCCGAACCGACC
CGAACCGACCCGAACCGACC

Downstream 100 bases:

>100_bases
CGCCATGCAGCTCTACAGCTTCTTCAACAGCTCCACGTCGTACCGCGTGCGCATCGCGCTGGCGCTCAAGGGGCTGCCGT
ACGACTACCTGCCGGTCAAC

Product: isomerase-decarboxylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 232; Mature: 231

Protein sequence:

>232_residues
MTYVFTPPALTAIPVAGSSEQFAVRRVYCVGRNYAAHAREMGFDPDREPPFFFCKPADAIVPVADGQTLALPYPTQTQNY
HYEAELVAVIGKAGADIAVDDALDHVWGYAVGLDMTRRDLQMKMREMGRPWEIGKAFDVSAPVGPIRRASDIGHPRQAGI
WLTVNGEAKQRSDVSHLIWSVAETVACLSQFFRLEPGDVIFTGTPEGVGAVKPGDTIATGVDGLGELNVRIA

Sequences:

>Translated_232_residues
MTYVFTPPALTAIPVAGSSEQFAVRRVYCVGRNYAAHAREMGFDPDREPPFFFCKPADAIVPVADGQTLALPYPTQTQNY
HYEAELVAVIGKAGADIAVDDALDHVWGYAVGLDMTRRDLQMKMREMGRPWEIGKAFDVSAPVGPIRRASDIGHPRQAGI
WLTVNGEAKQRSDVSHLIWSVAETVACLSQFFRLEPGDVIFTGTPEGVGAVKPGDTIATGVDGLGELNVRIA
>Mature_231_residues
TYVFTPPALTAIPVAGSSEQFAVRRVYCVGRNYAAHAREMGFDPDREPPFFFCKPADAIVPVADGQTLALPYPTQTQNYH
YEAELVAVIGKAGADIAVDDALDHVWGYAVGLDMTRRDLQMKMREMGRPWEIGKAFDVSAPVGPIRRASDIGHPRQAGIW
LTVNGEAKQRSDVSHLIWSVAETVACLSQFFRLEPGDVIFTGTPEGVGAVKPGDTIATGVDGLGELNVRIA

Specific function: Unknown

COG id: COG0179

COG function: function code Q; 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAH family [H]

Homologues:

Organism=Homo sapiens, GI13654274, Length=207, Percent_Identity=39.6135265700483, Blast_Score=155, Evalue=3e-38,
Organism=Homo sapiens, GI215422413, Length=204, Percent_Identity=40.1960784313725, Blast_Score=154, Evalue=5e-38,
Organism=Homo sapiens, GI66348062, Length=200, Percent_Identity=41, Blast_Score=154, Evalue=6e-38,
Organism=Homo sapiens, GI156231349, Length=208, Percent_Identity=37.9807692307692, Blast_Score=132, Evalue=3e-31,
Organism=Homo sapiens, GI40786394, Length=208, Percent_Identity=37.5, Blast_Score=128, Evalue=4e-30,
Organism=Escherichia coli, GI1787428, Length=208, Percent_Identity=38.9423076923077, Blast_Score=144, Evalue=6e-36,
Organism=Caenorhabditis elegans, GI17557057, Length=196, Percent_Identity=37.7551020408163, Blast_Score=144, Evalue=4e-35,
Organism=Saccharomyces cerevisiae, GI6324161, Length=223, Percent_Identity=28.6995515695067, Blast_Score=117, Evalue=2e-27,
Organism=Drosophila melanogaster, GI28571789, Length=212, Percent_Identity=34.9056603773585, Blast_Score=121, Evalue=3e-28,
Organism=Drosophila melanogaster, GI28572127, Length=214, Percent_Identity=33.6448598130841, Blast_Score=110, Evalue=8e-25,
Organism=Drosophila melanogaster, GI24663695, Length=220, Percent_Identity=28.1818181818182, Blast_Score=88, Evalue=5e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002529
- InterPro:   IPR011234 [H]

Pfam domain/function: PF01557 FAA_hydrolase [H]

EC number: NA

Molecular weight: Translated: 25160; Mature: 25029

Theoretical pI: Translated: 5.08; Mature: 5.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTYVFTPPALTAIPVAGSSEQFAVRRVYCVGRNYAAHAREMGFDPDREPPFFFCKPADAI
CCEEECCCCCEEEECCCCCCCEEEEEEEEECCCHHHHHHHCCCCCCCCCCEEEECCCCCE
VPVADGQTLALPYPTQTQNYHYEAELVAVIGKAGADIAVDDALDHVWGYAVGLDMTRRDL
EEECCCCEEEECCCCCCCCEEEHEEEEEEEECCCCCEEHHHHHHHHHHHHHCCCHHHHHH
QMKMREMGRPWEIGKAFDVSAPVGPIRRASDIGHPRQAGIWLTVNGEAKQRSDVSHLIWS
HHHHHHCCCCCCCCCEEECCCCCCCHHHHHHCCCCCCCCEEEEECCCCHHHHHHHHHHHH
VAETVACLSQFFRLEPGDVIFTGTPEGVGAVKPGDTIATGVDGLGELNVRIA
HHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCCCEECCCCCCCCEEEEEC
>Mature Secondary Structure 
TYVFTPPALTAIPVAGSSEQFAVRRVYCVGRNYAAHAREMGFDPDREPPFFFCKPADAI
CEEECCCCCEEEECCCCCCCEEEEEEEEECCCHHHHHHHCCCCCCCCCCEEEECCCCCE
VPVADGQTLALPYPTQTQNYHYEAELVAVIGKAGADIAVDDALDHVWGYAVGLDMTRRDL
EEECCCCEEEECCCCCCCCEEEHEEEEEEEECCCCCEEHHHHHHHHHHHHHCCCHHHHHH
QMKMREMGRPWEIGKAFDVSAPVGPIRRASDIGHPRQAGIWLTVNGEAKQRSDVSHLIWS
HHHHHHCCCCCCCCCEEECCCCCCCHHHHHHCCCCCCCCEEEEECCCCHHHHHHHHHHHH
VAETVACLSQFFRLEPGDVIFTGTPEGVGAVKPGDTIATGVDGLGELNVRIA
HHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCCCEECCCCCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12622808 [H]