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The map label for this gene is efp

Identifier: 17545788

GI number: 17545788

Start: 1121490

End: 1122056

Strand: Reverse

Name: efp

Synonym: RSc1069

Alternate gene names: 17545788

Gene position: 1122056-1121490 (Counterclockwise)

Preceding gene: 17545789

Following gene: 17545765

Centisome position: 30.19

GC content: 59.08

Gene sequence:

>567_bases
ATGGCCTTGAAAATCGCGCAAGAACTCCGCGCTGGTAACGTTTTCATGATCGGCAACGACCCGATGGTCGTGCTCAAGAC
CGAATACAGCCGCTCCGGCCGCAACGCCGCTGTCGTCAAGATGAAGTACAAGAACCTGCTGACCGGCGCGCCGTCGGAAT
CGGTGTTCAAGGCCGACGACAAGATGGACCAGATCATCCTCGACAAGAAGGAGTGCACCTACTCCTACTTCGCCGATCCG
ATGTACGTGTTCATGGACACCGACTACAACCAGTACGAAGTGGAAGCCGACAGCATGGGCGACGCGATCCACTACCTGGA
AGACGGCATGGCCGCCGAAGTGACCTTCTACAACGAGAAGGCCATCTCGGTCGAACTGCCGACCACGCTGGTCCGCGAAA
TCGAATACACCGAGCCGGCCGTCAAGGGCGACACCTCGTCGGGCAAGGTGCTGAAGATGGCCAAGATCAAGGGCGGCTTC
GAGATCCAGGTCCCGCTGTTCTGCAGCACCGGCGACAAGATCGAAATCGACACCCGTACGCACGAGTACCGCAGCCGCGC
CAACTGA

Upstream 100 bases:

>100_bases
CGGCCCCGGCTTTCACCTGGTTCGCGCGACCCGAGGGTATCGCGCGGTTGCATCGTTGCTCGGCACGCATCGAACCCTCT
TACTTTTCAGGAAATTAGAA

Downstream 100 bases:

>100_bases
TTCGGCGTTCTGCAAACAAAAAAGGCAGCCTGGCGCTGCCTTTTTTGTTGCCCGCGAAAAAGCGATGGAGCGGGCGATGG
CGCAGCAAGACCTCGCACCC

Product: elongation factor P

Products: NA

Alternate protein names: EF-P

Number of amino acids: Translated: 188; Mature: 187

Protein sequence:

>188_residues
MALKIAQELRAGNVFMIGNDPMVVLKTEYSRSGRNAAVVKMKYKNLLTGAPSESVFKADDKMDQIILDKKECTYSYFADP
MYVFMDTDYNQYEVEADSMGDAIHYLEDGMAAEVTFYNEKAISVELPTTLVREIEYTEPAVKGDTSSGKVLKMAKIKGGF
EIQVPLFCSTGDKIEIDTRTHEYRSRAN

Sequences:

>Translated_188_residues
MALKIAQELRAGNVFMIGNDPMVVLKTEYSRSGRNAAVVKMKYKNLLTGAPSESVFKADDKMDQIILDKKECTYSYFADP
MYVFMDTDYNQYEVEADSMGDAIHYLEDGMAAEVTFYNEKAISVELPTTLVREIEYTEPAVKGDTSSGKVLKMAKIKGGF
EIQVPLFCSTGDKIEIDTRTHEYRSRAN
>Mature_187_residues
ALKIAQELRAGNVFMIGNDPMVVLKTEYSRSGRNAAVVKMKYKNLLTGAPSESVFKADDKMDQIILDKKECTYSYFADPM
YVFMDTDYNQYEVEADSMGDAIHYLEDGMAAEVTFYNEKAISVELPTTLVREIEYTEPAVKGDTSSGKVLKMAKIKGGFE
IQVPLFCSTGDKIEIDTRTHEYRSRAN

Specific function: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing t

COG id: COG0231

COG function: function code J; Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the elongation factor P family

Homologues:

Organism=Escherichia coli, GI1790590, Length=187, Percent_Identity=33.6898395721925, Blast_Score=103, Evalue=7e-24,
Organism=Escherichia coli, GI87082061, Length=188, Percent_Identity=32.4468085106383, Blast_Score=87, Evalue=1e-18,

Paralogues:

None

Copy number: 1600 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): EFP_RALSO (Q8Y0H5)

Other databases:

- EMBL:   AL646052
- RefSeq:   NP_519190.1
- ProteinModelPortal:   Q8Y0H5
- GeneID:   1219878
- GenomeReviews:   AL646052_GR
- KEGG:   rso:RSc1069
- NMPDR:   fig|267608.1.peg.1069
- HOGENOM:   HBG303311
- OMA:   MISSNDF
- ProtClustDB:   PRK00529
- BioCyc:   RSOL267608:RSC1069-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00141
- InterPro:   IPR015365
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR020599
- InterPro:   IPR013185
- InterPro:   IPR001059
- InterPro:   IPR013852
- InterPro:   IPR011768
- InterPro:   IPR014722
- InterPro:   IPR008991
- Gene3D:   G3DSA:2.40.50.140
- Gene3D:   G3DSA:2.30.30.30
- PIRSF:   PIRSF005901
- SMART:   SM00841
- TIGRFAMs:   TIGR00038

Pfam domain/function: PF01132 EFP; PF08207 EFP_N; PF09285 Elong-fact-P_C; SSF50249 Nucleic_acid_OB; SSF50104 Transl_SH3_like

EC number: NA

Molecular weight: Translated: 21164; Mature: 21033

Theoretical pI: Translated: 4.72; Mature: 4.72

Prosite motif: PS01275 EFP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
5.3 %Met     (Translated Protein)
6.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALKIAQELRAGNVFMIGNDPMVVLKTEYSRSGRNAAVVKMKYKNLLTGAPSESVFKADD
CCEEEHHHHCCCCEEEECCCCEEEEEECCCCCCCCEEEEEEEEHHHHCCCCCCCEEECCC
KMDQIILDKKECTYSYFADPMYVFMDTDYNQYEVEADSMGDAIHYLEDGMAAEVTFYNEK
CHHHEEECCCCCCEEECCCEEEEEEECCCCEEEEECCCCCCHHHHHCCCCEEEEEEECCE
AISVELPTTLVREIEYTEPAVKGDTSSGKVLKMAKIKGGFEIQVPLFCSTGDKIEIDTRT
EEEEECCHHHHHHHHCCCCCCCCCCCCCCEEEEEECCCCEEEEEEEEECCCCEEEEECCC
HEYRSRAN
HHHHHCCC
>Mature Secondary Structure 
ALKIAQELRAGNVFMIGNDPMVVLKTEYSRSGRNAAVVKMKYKNLLTGAPSESVFKADD
CEEEHHHHCCCCEEEECCCCEEEEEECCCCCCCCEEEEEEEEHHHHCCCCCCCEEECCC
KMDQIILDKKECTYSYFADPMYVFMDTDYNQYEVEADSMGDAIHYLEDGMAAEVTFYNEK
CHHHEEECCCCCCEEECCCEEEEEEECCCCEEEEECCCCCCHHHHHCCCCEEEEEEECCE
AISVELPTTLVREIEYTEPAVKGDTSSGKVLKMAKIKGGFEIQVPLFCSTGDKIEIDTRT
EEEEECCHHHHHHHHCCCCCCCCCCCCCCEEEEEECCCCEEEEEEEEECCCCEEEEECCC
HEYRSRAN
HHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11823852