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The map label for this gene is alsB [H]

Identifier: 17545736

GI number: 17545736

Start: 1070954

End: 1071913

Strand: Reverse

Name: alsB [H]

Synonym: RSc1017

Alternate gene names: 17545736

Gene position: 1071913-1070954 (Counterclockwise)

Preceding gene: 17545746

Following gene: 17545735

Centisome position: 28.84

GC content: 68.44

Gene sequence:

>960_bases
ATGGATTCCAGCCGACGCCGCGCCCTGCGACTCAGCGCGGGCTCCGCACTCGCCCTTGCCTTGCCCTTTCCGTTCGCCGC
GTCGCGTGCCGCCAACCGGCCGCCCAAGATCGCGCTGGTGATGAAATCGCTGGCCAACGAGTTCTTCCTGACCATGGAGA
ACGGGGCGCGGGCCCACCAGAAGACGCACGCATCGGAATACACGCTGCTGGCCAACGGCATCCGCGACGAAACCGACACC
GGCGGGCAGATCCGCCTGATCGAGCAGATGATCGTGGCGCGCGTCGATGCGCTGGTGCTGGCGCCGGCCGACTCGAAGGC
GCTGGTGCCGGTGGTCAGGAAGGCGGTCGATGCAGGCATCCTGGTCGTCAACATCGACAACCGGCTCGACCCGGAAACGC
TCAGAGACAAGGGCCTGAACGTGCCGTTCGTCGGCCCCGACAACCGCAAGGGCGCACGCCTGGTGGGCGAGTTCGTCGCC
AAGTCGCTCAAGCCGGGCGATGCGATCGGCATCATCGAGGGCATCCCGACCACCACCAACGCCCAGCAGCGCACGGCGGG
CTTCCGGGATGCCGCGCAGGGCGCGGGGCTCAGAATCGTCAGCGTGCAATCGGGCGAGTGGGAAATCGACAAGGGCAACA
AGGTGGCCGCCGCGATGCTGCGCGCCCAGCCCGACATCAAGGCCCTGCTGTGCGGCAACGACAACATGGCGATCGGCGCG
GTATCGGCCGTGCGCGCCGCGGGCAAGACCGGCAGGGTCCTGATCGGCGGCTATGACGACATTGCCGCCATCAAGGCCAT
GCTGGCCGACGGCCGCGTCGCGGCGACCGCCGACCAGCACGCCGGCCAGCAAGCGGTGTACGGCATCCAGACCGCGCTCA
AGGCCCTAGCGGCGAAAACACCGCAGGCGCAGCTGGGCGGGGTGATCGAAACACCGGTCAACCTGGTCACCCGCACCTGA

Upstream 100 bases:

>100_bases
ACGTTTGCGAGCGACGCGGCGCGATTGCCCTTTATGATGTCGGGACAACGACGACCGCGCCTCACCCCCTGCCCAGACAG
GCACTCCTGGAGGAGACACC

Downstream 100 bases:

>100_bases
ACCGGGCCTGCCAGCCGCCGCCAGCAATGCCCGCCATGACCACCGTCCCTGCACCGCGCACACCGCTGCTGCGGGCGTCC
GCCCTCAGCAAGCACTACGC

Product: sugar-binding periplasmic (PBP) ABC transporter protein

Products: ADP; phosphate; ribose [Cytoplasm]; D-allose [Cytoplasm] [C]

Alternate protein names: ALBP [H]

Number of amino acids: Translated: 319; Mature: 319

Protein sequence:

>319_residues
MDSSRRRALRLSAGSALALALPFPFAASRAANRPPKIALVMKSLANEFFLTMENGARAHQKTHASEYTLLANGIRDETDT
GGQIRLIEQMIVARVDALVLAPADSKALVPVVRKAVDAGILVVNIDNRLDPETLRDKGLNVPFVGPDNRKGARLVGEFVA
KSLKPGDAIGIIEGIPTTTNAQQRTAGFRDAAQGAGLRIVSVQSGEWEIDKGNKVAAAMLRAQPDIKALLCGNDNMAIGA
VSAVRAAGKTGRVLIGGYDDIAAIKAMLADGRVAATADQHAGQQAVYGIQTALKALAAKTPQAQLGGVIETPVNLVTRT

Sequences:

>Translated_319_residues
MDSSRRRALRLSAGSALALALPFPFAASRAANRPPKIALVMKSLANEFFLTMENGARAHQKTHASEYTLLANGIRDETDT
GGQIRLIEQMIVARVDALVLAPADSKALVPVVRKAVDAGILVVNIDNRLDPETLRDKGLNVPFVGPDNRKGARLVGEFVA
KSLKPGDAIGIIEGIPTTTNAQQRTAGFRDAAQGAGLRIVSVQSGEWEIDKGNKVAAAMLRAQPDIKALLCGNDNMAIGA
VSAVRAAGKTGRVLIGGYDDIAAIKAMLADGRVAATADQHAGQQAVYGIQTALKALAAKTPQAQLGGVIETPVNLVTRT
>Mature_319_residues
MDSSRRRALRLSAGSALALALPFPFAASRAANRPPKIALVMKSLANEFFLTMENGARAHQKTHASEYTLLANGIRDETDT
GGQIRLIEQMIVARVDALVLAPADSKALVPVVRKAVDAGILVVNIDNRLDPETLRDKGLNVPFVGPDNRKGARLVGEFVA
KSLKPGDAIGIIEGIPTTTNAQQRTAGFRDAAQGAGLRIVSVQSGEWEIDKGNKVAAAMLRAQPDIKALLCGNDNMAIGA
VSAVRAAGKTGRVLIGGYDDIAAIKAMLADGRVAATADQHAGQQAVYGIQTALKALAAKTPQAQLGGVIETPVNLVTRT

Specific function: Part of the binding-protein-dependent transport system AlsBAC for D-allose [H]

COG id: COG1879

COG function: function code G; ABC-type sugar transport system, periplasmic component

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 2 family [H]

Homologues:

Organism=Escherichia coli, GI1790526, Length=296, Percent_Identity=31.0810810810811, Blast_Score=122, Evalue=3e-29,
Organism=Escherichia coli, GI1790192, Length=293, Percent_Identity=29.0102389078498, Blast_Score=111, Evalue=8e-26,
Organism=Escherichia coli, GI1790674, Length=204, Percent_Identity=29.9019607843137, Blast_Score=84, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001761 [H]

Pfam domain/function: PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 33437; Mature: 33437

Theoretical pI: Translated: 10.43; Mature: 10.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDSSRRRALRLSAGSALALALPFPFAASRAANRPPKIALVMKSLANEFFLTMENGARAHQ
CCCCCCEEEEECCCCEEEEEECCCHHHHHCCCCCCHHHHHHHHHHHHEEEEECCCCHHHH
KTHASEYTLLANGIRDETDTGGQIRLIEQMIVARVDALVLAPADSKALVPVVRKAVDAGI
HHCCCCEEEEECCCCCCCCCCCEEHHHHHHHHHHHCEEEECCCCCCHHHHHHHHHHCCCE
LVVNIDNRLDPETLRDKGLNVPFVGPDNRKGARLVGEFVAKSLKPGDAIGIIEGIPTTTN
EEEEECCCCCHHHHHHCCCCCCEECCCCCCHHHHHHHHHHHHCCCCCCEEEEECCCCCCC
AQQRTAGFRDAAQGAGLRIVSVQSGEWEIDKGNKVAAAMLRAQPDIKALLCGNDNMAIGA
CHHHHCCCHHHHCCCCEEEEEECCCCEEECCCCHHHHHHHHCCCCCEEEEECCCCCEEHH
VSAVRAAGKTGRVLIGGYDDIAAIKAMLADGRVAATADQHAGQQAVYGIQTALKALAAKT
HHHHHHCCCCCEEEEECCHHHHHHHHHHHCCCEEECCHHHCCHHHHHHHHHHHHHHHCCC
PQAQLGGVIETPVNLVTRT
CHHHHCCCHHCCHHHHCCC
>Mature Secondary Structure
MDSSRRRALRLSAGSALALALPFPFAASRAANRPPKIALVMKSLANEFFLTMENGARAHQ
CCCCCCEEEEECCCCEEEEEECCCHHHHHCCCCCCHHHHHHHHHHHHEEEEECCCCHHHH
KTHASEYTLLANGIRDETDTGGQIRLIEQMIVARVDALVLAPADSKALVPVVRKAVDAGI
HHCCCCEEEEECCCCCCCCCCCEEHHHHHHHHHHHCEEEECCCCCCHHHHHHHHHHCCCE
LVVNIDNRLDPETLRDKGLNVPFVGPDNRKGARLVGEFVAKSLKPGDAIGIIEGIPTTTN
EEEEECCCCCHHHHHHCCCCCCEECCCCCCHHHHHHHHHHHHCCCCCCEEEEECCCCCCC
AQQRTAGFRDAAQGAGLRIVSVQSGEWEIDKGNKVAAAMLRAQPDIKALLCGNDNMAIGA
CHHHHCCCHHHHCCCCEEEEEECCCCEEECCCCHHHHHHHHCCCCCEEEEECCCCCEEHH
VSAVRAAGKTGRVLIGGYDDIAAIKAMLADGRVAATADQHAGQQAVYGIQTALKALAAKT
HHHHHHCCCCCEEEEECCHHHHHHHHHHHCCCEEECCHHHCCHHHHHHHHHHHHHHHCCC
PQAQLGGVIETPVNLVTRT
CHHHHCCCHHCCHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; H2O; ribose [Periplasm]; D-allose [Periplasm]; ATP [C]

Specific reaction: ATP + H2O + ribose [Periplasm] = ADP + phosphate + ribose [Cytoplasm] D-allose [Periplasm] + ATP + H2O = D-allose [Cytoplasm] + ADP + phosphate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7610040; 9278503; 8576032; 9401019; 10064713 [H]