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The map label for this gene is lysN [H]

Identifier: 17545704

GI number: 17545704

Start: 1036110

End: 1037330

Strand: Reverse

Name: lysN [H]

Synonym: RSc0985

Alternate gene names: 17545704

Gene position: 1037330-1036110 (Counterclockwise)

Preceding gene: 17545705

Following gene: 17545703

Centisome position: 27.91

GC content: 67.98

Gene sequence:

>1221_bases
GTGGGCGTCTCCACACTGAAGGACCATACCATGGACCACCCCGCCTGCACCTTCTCCCGCCGCGCGCAACAGCTGACCAG
CTCGGCGATCCGGGAAATCCTCAAGATCACCGAGCGCCCCGAGGTGATCTCGTTCGCCGGCGGCCTGCCTTCGCCGGTGA
CCTTCCCGGTCGAGGCGATCCAGGCGGCGTGCGCCCGCATGTTCGCGGACAATCCGCAGGCGTCGCTGCAGTACACCCCG
ACCGAAGGCCTGTCGATGCTGCGCGAGTGGATCGCCCAGCGCCACGGCACCACCGCGTCGCGCGTGCTGATCACCACCGG
CTCGCAACAGGGCCTGGACCTGCTGGGCAAGATCTTCATCGACCCGCAGAGCAAAGTGCTGGTCGAAACGCCGACCTACC
TCGGCGCGCTGCAGGCGTTCTCGCTGTTCGAGCCGAGCTACGCCTCGGTGCCGACCGATGAGCGCGGCCTGCTGCCCGAA
GCGCTCACGCCCGAACTCACCGCCGGCGCGCGCTTCTTCTACACCATCCCGAACTTCCAGAACCCGACCGGCCGCCGCCT
GCCGCTCGAGCGCCGCCAGGCCCTGGTGGCCCGCGCGAAAGAACTCGGCGTGCTGCTGGTCGAAGACGATCCGTACGGCG
AGCTGAGCTATACCGGCGATGCCCTGCCGTCGCTGCGCTCGCTCAATCCGGACGGCGTGGTCTACATGGGCTCGTTCTCG
AAGATCCTGGCGCCGGGCATGCGCCTGGGCTACATCATCGCCCCCGAGCCGATCCACTTCAAACTCGTGCAGGCCAAGCA
GGCATCCGACCTGCACACGCCCAGCTTCACGCAGCGCGTGGCCTACGAAGTGCTGAAGACCGGCCTGCTCGACACCCACA
TCCCGAGCATCCGCACCCTGTACGGCAAGCAGTGCGAGACGATGCTGGATGCGCTCACGCGCCACATGCCGGCCGGCGTG
CACTGGAACCGTCCGGAAGGCGGCATGTTCATCTGGGTGGAAGTGCCGGAAGGCATCGACACCATGGCGCTGCTGGAAAA
GGCGGTCGCGCGCAACGTGGCCTTCGTGCCGGGCGCGCCGTTCTACGCCAACGCACCGCGCCGCAACACCATGCGCCTGG
CCTTCGTGACGGTGTCGCCGGAGCGCATCGAACAGGGCATCACGGTGCTGGGCGAGCTGATCCGCGCCGAGATCGCCGCG
CTCACGCCCAAGGCCGCGTAA

Upstream 100 bases:

>100_bases
GCGCCGCATTTGCCGCGCCGCGCAACGGCTGCCGCGTGCCAGAGCGGGCCGTTGCCTGCTATCCTTTCCGTCTTTTGCTC
ACCAGGCGTCCGCTCAAAAG

Downstream 100 bases:

>100_bases
TTCACGCACGCGACTGACAATCACCACCGACACCAAGGAGCCGACGTCGATGCTGCGGATCTGGGGGAGACTCTCTTCGG
TCAACGTGCAGAAAGTGGTC

Product: aminotransferase

Products: NA

Alternate protein names: 2-aminoadipate aminotransferase; Alpha-aminoadipate aminotransferase; AAA-AT; AadAT [H]

Number of amino acids: Translated: 406; Mature: 405

Protein sequence:

>406_residues
MGVSTLKDHTMDHPACTFSRRAQQLTSSAIREILKITERPEVISFAGGLPSPVTFPVEAIQAACARMFADNPQASLQYTP
TEGLSMLREWIAQRHGTTASRVLITTGSQQGLDLLGKIFIDPQSKVLVETPTYLGALQAFSLFEPSYASVPTDERGLLPE
ALTPELTAGARFFYTIPNFQNPTGRRLPLERRQALVARAKELGVLLVEDDPYGELSYTGDALPSLRSLNPDGVVYMGSFS
KILAPGMRLGYIIAPEPIHFKLVQAKQASDLHTPSFTQRVAYEVLKTGLLDTHIPSIRTLYGKQCETMLDALTRHMPAGV
HWNRPEGGMFIWVEVPEGIDTMALLEKAVARNVAFVPGAPFYANAPRRNTMRLAFVTVSPERIEQGITVLGELIRAEIAA
LTPKAA

Sequences:

>Translated_406_residues
MGVSTLKDHTMDHPACTFSRRAQQLTSSAIREILKITERPEVISFAGGLPSPVTFPVEAIQAACARMFADNPQASLQYTP
TEGLSMLREWIAQRHGTTASRVLITTGSQQGLDLLGKIFIDPQSKVLVETPTYLGALQAFSLFEPSYASVPTDERGLLPE
ALTPELTAGARFFYTIPNFQNPTGRRLPLERRQALVARAKELGVLLVEDDPYGELSYTGDALPSLRSLNPDGVVYMGSFS
KILAPGMRLGYIIAPEPIHFKLVQAKQASDLHTPSFTQRVAYEVLKTGLLDTHIPSIRTLYGKQCETMLDALTRHMPAGV
HWNRPEGGMFIWVEVPEGIDTMALLEKAVARNVAFVPGAPFYANAPRRNTMRLAFVTVSPERIEQGITVLGELIRAEIAA
LTPKAA
>Mature_405_residues
GVSTLKDHTMDHPACTFSRRAQQLTSSAIREILKITERPEVISFAGGLPSPVTFPVEAIQAACARMFADNPQASLQYTPT
EGLSMLREWIAQRHGTTASRVLITTGSQQGLDLLGKIFIDPQSKVLVETPTYLGALQAFSLFEPSYASVPTDERGLLPEA
LTPELTAGARFFYTIPNFQNPTGRRLPLERRQALVARAKELGVLLVEDDPYGELSYTGDALPSLRSLNPDGVVYMGSFSK
ILAPGMRLGYIIAPEPIHFKLVQAKQASDLHTPSFTQRVAYEVLKTGLLDTHIPSIRTLYGKQCETMLDALTRHMPAGVH
WNRPEGGMFIWVEVPEGIDTMALLEKAVARNVAFVPGAPFYANAPRRNTMRLAFVTVSPERIEQGITVLGELIRAEIAAL
TPKAA

Specific function: Catalyzes the transfer of an amino group between 2- oxoadipate (2-OA) and glutamate (Glu) to yield alpha-aminodipate (AAA). It can also transaminate glutamate, leucine, and aromatic amino acids. It also conbtributes in the biosynthesis of other amino acid

COG id: COG1167

COG function: function code KE; Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI7705897, Length=411, Percent_Identity=30.1703163017032, Blast_Score=192, Evalue=4e-49,
Organism=Homo sapiens, GI33469970, Length=411, Percent_Identity=30.1703163017032, Blast_Score=192, Evalue=4e-49,
Organism=Escherichia coli, GI1787710, Length=381, Percent_Identity=30.4461942257218, Blast_Score=156, Evalue=2e-39,
Organism=Escherichia coli, GI1790797, Length=339, Percent_Identity=29.7935103244838, Blast_Score=143, Evalue=2e-35,
Organism=Escherichia coli, GI48994949, Length=403, Percent_Identity=26.302729528536, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1788722, Length=379, Percent_Identity=25.5936675461741, Blast_Score=72, Evalue=6e-14,
Organism=Saccharomyces cerevisiae, GI6321000, Length=434, Percent_Identity=26.4976958525346, Blast_Score=101, Evalue=2e-22,
Organism=Saccharomyces cerevisiae, GI6321929, Length=348, Percent_Identity=25.8620689655172, Blast_Score=82, Evalue=2e-16,
Organism=Drosophila melanogaster, GI21356535, Length=397, Percent_Identity=25.6926952141058, Blast_Score=101, Evalue=7e-22,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.39 [H]

Molecular weight: Translated: 44527; Mature: 44396

Theoretical pI: Translated: 7.25; Mature: 7.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGVSTLKDHTMDHPACTFSRRAQQLTSSAIREILKITERPEVISFAGGLPSPVTFPVEAI
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCHHHH
QAACARMFADNPQASLQYTPTEGLSMLREWIAQRHGTTASRVLITTGSQQGLDLLGKIFI
HHHHHHHHCCCCCCCEEECCHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCHHHHHHHEE
DPQSKVLVETPTYLGALQAFSLFEPSYASVPTDERGLLPEALTPELTAGARFFYTIPNFQ
CCCCCEEEECCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCC
NPTGRRLPLERRQALVARAKELGVLLVEDDPYGELSYTGDALPSLRSLNPDGVVYMGSFS
CCCCCCCCHHHHHHHHHHHHHCCEEEECCCCCCCCCCCCCCCCHHHCCCCCCEEEECCCH
KILAPGMRLGYIIAPEPIHFKLVQAKQASDLHTPSFTQRVAYEVLKTGLLDTHIPSIRTL
HHHCCCCCEEEEECCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHCCHHHCCCHHHHH
YGKQCETMLDALTRHMPAGVHWNRPEGGMFIWVEVPEGIDTMALLEKAVARNVAFVPGAP
HHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHCCEEECCCCC
FYANAPRRNTMRLAFVTVSPERIEQGITVLGELIRAEIAALTPKAA
CCCCCCCCCCEEEEEEEECHHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
GVSTLKDHTMDHPACTFSRRAQQLTSSAIREILKITERPEVISFAGGLPSPVTFPVEAI
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCHHHH
QAACARMFADNPQASLQYTPTEGLSMLREWIAQRHGTTASRVLITTGSQQGLDLLGKIFI
HHHHHHHHCCCCCCCEEECCHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCHHHHHHHEE
DPQSKVLVETPTYLGALQAFSLFEPSYASVPTDERGLLPEALTPELTAGARFFYTIPNFQ
CCCCCEEEECCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCC
NPTGRRLPLERRQALVARAKELGVLLVEDDPYGELSYTGDALPSLRSLNPDGVVYMGSFS
CCCCCCCCHHHHHHHHHHHHHCCEEEECCCCCCCCCCCCCCCCHHHCCCCCCEEEECCCH
KILAPGMRLGYIIAPEPIHFKLVQAKQASDLHTPSFTQRVAYEVLKTGLLDTHIPSIRTL
HHHCCCCCEEEEECCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHCCHHHCCCHHHHH
YGKQCETMLDALTRHMPAGVHWNRPEGGMFIWVEVPEGIDTMALLEKAVARNVAFVPGAP
HHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHCCEEECCCCC
FYANAPRRNTMRLAFVTVSPERIEQGITVLGELIRAEIAALTPKAA
CCCCCCCCCCEEEEEEEECHHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA