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The map label for this gene is rsgA

Identifier: 17545659

GI number: 17545659

Start: 988640

End: 989596

Strand: Reverse

Name: rsgA

Synonym: RSc0940

Alternate gene names: 17545659

Gene position: 989596-988640 (Counterclockwise)

Preceding gene: 17545660

Following gene: 17545658

Centisome position: 26.63

GC content: 68.13

Gene sequence:

>957_bases
ATGACGCGCGGCAAACCGGGCCGCGCGGGTCACGACAGGCGGCACGCCAGCACCGGCGAACATGGGCTGGTGATCGCCGC
GCATGGCCGTCATTACCTCGTCGAGCGGAAAGGCGGCGGCCTGCTGCAATGCTTTCCGCGCGGCAAGCGCAGCGAATGCG
CGGTCGGCGATCGCGTCATCTTCGAGGCCACCGCCGTCGACCAGGGCGTGGTGGTACGCGTGGAGGAACGCCGCAACCTG
CTGCACCGATCAGACCAGTTCAAGTCCAAGCAGCTGGCCGCCAATATCGATCAGGTCCTGATCATGCTCGGCACCGAGCC
GGGCTTTTCCGAAGACCTGCTCGGCCGCGCGCTGGTGGCGGCGGAGTCGCTGGGCATCACCCCGCTGATCCTGCTCAACA
AGATCGACCTGACCGCGCGGCTCGAGACGGCCCGGGCGCGATTGGCACTGTATCGCGCGCTCGGCTACGCGGTCGTGGAA
CTGTCGGTGCACGCCGCCCCCGAGGCGGCGCACGCCGTGCTGGCGGCGCACGTGGCGGGGCGCTCCTCGATCCTGATCGG
GCAGTCCGGCATGGGCAAGTCGTCTCTGCTGAACCTGCTGATTCCGGGTGTGGACGCGCAGACCCGCGAGATCTCGGAAA
AGCTCGACTCCGGCAAGCACACCACGACCTTCACGCGGCTCTATCACCTGCCCTCCGGCTGGGGCCACGGCGGCACGCTG
ATCGACTCGCCCGGCTTCCAGGAATTCGGCCTGCACCACCTGACCGAAGGCATGCTGGAGCGCGCCTTCCCCGAATTCCG
CCCGCGCCTGACCGAATGCCGCTTTTACAACTGCCGCCACCTGCAGGAGCCCGGCTGTGGCATCCTGGGGGCGATGGCCG
AGGGCAAGATCGATCCGCGCCGCCACGCACTGTACGCGCAGCTGCTGCACGAATCGGAGCAACAGAAGCCCTGGTGA

Upstream 100 bases:

>100_bases
ACAATGCTTCGACCCTGACGCCCGACCCGGTCTACTCGGCGTTCTACTACTCCCACCCCACCGCGTCGCAGCGCGTGGCA
CGACTGGTGCAGGCTGCCGC

Downstream 100 bases:

>100_bases
CCCAACCGGGAGGAGGACAGATCGATGAAACTGCTGGTCAGCAGTCCATCGCTCGGCCTGGCGGCACACTGGCAGAACGT
GCTGGCCGCAGCCGGCATCC

Product: ribosome-associated GTPase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 318; Mature: 317

Protein sequence:

>318_residues
MTRGKPGRAGHDRRHASTGEHGLVIAAHGRHYLVERKGGGLLQCFPRGKRSECAVGDRVIFEATAVDQGVVVRVEERRNL
LHRSDQFKSKQLAANIDQVLIMLGTEPGFSEDLLGRALVAAESLGITPLILLNKIDLTARLETARARLALYRALGYAVVE
LSVHAAPEAAHAVLAAHVAGRSSILIGQSGMGKSSLLNLLIPGVDAQTREISEKLDSGKHTTTFTRLYHLPSGWGHGGTL
IDSPGFQEFGLHHLTEGMLERAFPEFRPRLTECRFYNCRHLQEPGCGILGAMAEGKIDPRRHALYAQLLHESEQQKPW

Sequences:

>Translated_318_residues
MTRGKPGRAGHDRRHASTGEHGLVIAAHGRHYLVERKGGGLLQCFPRGKRSECAVGDRVIFEATAVDQGVVVRVEERRNL
LHRSDQFKSKQLAANIDQVLIMLGTEPGFSEDLLGRALVAAESLGITPLILLNKIDLTARLETARARLALYRALGYAVVE
LSVHAAPEAAHAVLAAHVAGRSSILIGQSGMGKSSLLNLLIPGVDAQTREISEKLDSGKHTTTFTRLYHLPSGWGHGGTL
IDSPGFQEFGLHHLTEGMLERAFPEFRPRLTECRFYNCRHLQEPGCGILGAMAEGKIDPRRHALYAQLLHESEQQKPW
>Mature_317_residues
TRGKPGRAGHDRRHASTGEHGLVIAAHGRHYLVERKGGGLLQCFPRGKRSECAVGDRVIFEATAVDQGVVVRVEERRNLL
HRSDQFKSKQLAANIDQVLIMLGTEPGFSEDLLGRALVAAESLGITPLILLNKIDLTARLETARARLALYRALGYAVVEL
SVHAAPEAAHAVLAAHVAGRSSILIGQSGMGKSSLLNLLIPGVDAQTREISEKLDSGKHTTTFTRLYHLPSGWGHGGTLI
DSPGFQEFGLHHLTEGMLERAFPEFRPRLTECRFYNCRHLQEPGCGILGAMAEGKIDPRRHALYAQLLHESEQQKPW

Specific function: May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover

COG id: COG1162

COG function: function code R; Predicted GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 engC GTPase domain

Homologues:

Organism=Escherichia coli, GI87082381, Length=308, Percent_Identity=39.6103896103896, Blast_Score=191, Evalue=4e-50,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RSGA_RALSO (Q8Y0V3)

Other databases:

- EMBL:   AL646052
- RefSeq:   NP_519061.1
- ProteinModelPortal:   Q8Y0V3
- SMR:   Q8Y0V3
- GeneID:   1219748
- GenomeReviews:   AL646052_GR
- KEGG:   rso:RSc0940
- NMPDR:   fig|267608.1.peg.940
- HOGENOM:   HBG652450
- OMA:   FRDCKHL
- ProtClustDB:   PRK00098
- BioCyc:   RSOL267608:RSC0940-MONOMER
- HAMAP:   MF_01820
- InterPro:   IPR010914
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR004881
- Gene3D:   G3DSA:2.40.50.140
- TIGRFAMs:   TIGR00157

Pfam domain/function: PF03193 DUF258; SSF50249 Nucleic_acid_OB

EC number: NA

Molecular weight: Translated: 34854; Mature: 34723

Theoretical pI: Translated: 8.98; Mature: 8.98

Prosite motif: PS50936 ENGC_GTPASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRGKPGRAGHDRRHASTGEHGLVIAAHGRHYLVERKGGGLLQCFPRGKRSECAVGDRVI
CCCCCCCCCCCCCCCCCCCCCCEEEEECCCEEEEEECCCCEEEECCCCCCCCCCCCCEEE
FEATAVDQGVVVRVEERRNLLHRSDQFKSKQLAANIDQVLIMLGTEPGFSEDLLGRALVA
EEEEECCCCEEEEEHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCHHHHHHHHHH
AESLGITPLILLNKIDLTARLETARARLALYRALGYAVVELSVHAAPEAAHAVLAAHVAG
HHHCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCHHHHHHHHHHHCC
RSSILIGQSGMGKSSLLNLLIPGVDAQTREISEKLDSGKHTTTFTRLYHLPSGWGHGGTL
CCEEEEECCCCCHHHHHHHHCCCCCHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCCCCE
IDSPGFQEFGLHHLTEGMLERAFPEFRPRLTECRFYNCRHLQEPGCGILGAMAEGKIDPR
ECCCCCHHHHHHHHHHHHHHHHCHHHCCCHHHHEEECCCCCCCCCCCEEEHHHCCCCCHH
RHALYAQLLHESEQQKPW
HHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TRGKPGRAGHDRRHASTGEHGLVIAAHGRHYLVERKGGGLLQCFPRGKRSECAVGDRVI
CCCCCCCCCCCCCCCCCCCCCEEEEECCCEEEEEECCCCEEEECCCCCCCCCCCCCEEE
FEATAVDQGVVVRVEERRNLLHRSDQFKSKQLAANIDQVLIMLGTEPGFSEDLLGRALVA
EEEEECCCCEEEEEHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCHHHHHHHHHH
AESLGITPLILLNKIDLTARLETARARLALYRALGYAVVELSVHAAPEAAHAVLAAHVAG
HHHCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCHHHHHHHHHHHCC
RSSILIGQSGMGKSSLLNLLIPGVDAQTREISEKLDSGKHTTTFTRLYHLPSGWGHGGTL
CCEEEEECCCCCHHHHHHHHCCCCCHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCCCCE
IDSPGFQEFGLHHLTEGMLERAFPEFRPRLTECRFYNCRHLQEPGCGILGAMAEGKIDPR
ECCCCCHHHHHHHHHHHHHHHHCHHHCCCHHHHEEECCCCCCCCCCCEEEHHHCCCCCHH
RHALYAQLLHESEQQKPW
HHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: GTP [C]

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11823852