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The map label for this gene is glnS

Identifier: 17545510

GI number: 17545510

Start: 834984

End: 836726

Strand: Reverse

Name: glnS

Synonym: RSc0791

Alternate gene names: 17545510

Gene position: 836726-834984 (Counterclockwise)

Preceding gene: 17545511

Following gene: 17545509

Centisome position: 22.51

GC content: 67.36

Gene sequence:

>1743_bases
ATGAGCCAAGATAACGCCACCGGCGCCGCTGCCGCCTCCACGTCCAACTTCCTGCGCCAGATCATCGATACCGACCTGGA
GCAGGGCACCTACGCCGGGCGCCAGGACACCGCCGGCCACGCCCTGCCGCCCATCATCACGCGCTTCCCGCCGGAGCCCA
ACGGTTACCTGCACATCGGCCACGCCAAGAGCATCTGGGTGAACTTCGGCCTGGCCAAGGAATACGGCGGCCGCTGCCAC
CTGCGCTTCGACGACACCAACCCGGTCAAGGAAGACACCGAGTACGTCGACTCCATCATCGACGCCGTGCACTGGCTCGG
CTACTCGTGGCAGAACGGCACCGGCGAGCACCTCTACTACGCCAGCGACTACTTCGAGCAGCTCTACGGCTTTGCCGAGG
TGCTGATCCAGCGCGGCGCCGCCTATATCGACAGCCAGAGCGCCGAGCAGATCGCCGCCAACCGTGGCGACTTCACCAGG
CCGGGCACGCCGTCGCCGTTCCGCGACCGTTCGGTGGAAGAGAACCTCGCGCTGTTCCGCGACATGCGAGCCGGCAAGTA
CCAGGACGGCCAGCACGTGCTGCGCGCCCGGATCGACATGGCCGCGCCCAACATCGTGATGCGCGATCCGGTGCTGTACC
GCATCCGCCACGCACACCACCACCGCACCGGCGACGCATGGTGCATCTACCCGATGTACGACTTCACGCATTGCATCTCC
GATGCGCTGGAGAACATCACGCATTCGCTGTGCACGCTGGAGTTCGAGAACAACCGCCCGCTGTACGACTGGGTGCTCGA
CCACCTGCGCGACGCCGGCGCGCTGCCCGCGCCGCTGCCGCACCAGTACGAATTCGCGCGCCTGCACCTCACGTACGCCA
TCACCAGCAAGCGCAAGCTGCTGCAGCTGGTGAACGAAAAGCGCGTGGACGGCTGGGACGACCCGCGCATGCCCACCCTG
GTGGGCATCCGCCGCCGCGGCTACACGCCGGAATCGATCCAGCTGTTCTGCGAGCGCGTGGGCGTCTCGAAGGCCGACAG
CTGGATCGACATGAGCATCCTGGAGGCCGCCGTGCGCGACGACCTCGATGCGCGCGCGCCGCGCTCGGTGGCGGTGCTGG
ACCCGGTCAAGCTCATCCTCGACAACGTGCCGGCGGACTTCAACGAGCCGTGCTCGGCCCCCGTGCACCCGAAGCAGCCC
GAGCTGGGCCGCCGCGAGTTCCCGCTCACGCGCGAGCTGTGGATCGAGCGCGAGGACTTCACCGAGACGCCGCCCAAGGG
CTACTTCCGCCTGTTCCCGGGCAACAAGGTGCGCCTGCGCTACGGCTACGTGATCGAATGCACGGGCTGCGACAAGGATG
CCGACGGCAACATCACCGCCGTGCACGCCAACATCATCCCGGACACCAAGAGCGGCACGCCGGGTGCGGACAGCGTCAAG
GTCAAGGGCAACATCCACTGGGTCAGCGCCGCGCATGCGCTCGAGGCCGAGGTGCGCCTGTACGATCGCCTGTTCACCGA
CCCGCAGCCGGACTCGGGCGACAAGAACTTCCTGGACGCGCTCAACCCCGACGCCAAGCGGGTCGTCACGGCCTACCTGG
AACCGACGCTGGCAACCGCCAAGCCGGAAGACCGCTTCCAGTTCGAGCGCCACGGCTACTTCGTGGCCGACCGCATCGAC
TCGCAGCCGGGCAAGCCCGTGTTCAACCGCGTGGTCGGCCTGAAGGACAGCTGGGGCAAGTAA

Upstream 100 bases:

>100_bases
CAGGCACTGGACGGCAGCCCGCGGCACGAATGAAACACGGCAACGCAGCACGAAGCGCCCGTCACGGTAAAATCGCAGGA
TTGCCGAATTTCGCCTGCCC

Downstream 100 bases:

>100_bases
GCACGGGCCCATGCTCGCCGTGGGCCCCTGACCAAGGAGGCATCATGCGTGCATGGATCTGGATGCTGGCGGGGGGGCTG
AGCACCTCCGCCCTTGCCGC

Product: glutaminyl-tRNA synthetase

Products: NA

Alternate protein names: Glutamine--tRNA ligase; GlnRS

Number of amino acids: Translated: 580; Mature: 579

Protein sequence:

>580_residues
MSQDNATGAAAASTSNFLRQIIDTDLEQGTYAGRQDTAGHALPPIITRFPPEPNGYLHIGHAKSIWVNFGLAKEYGGRCH
LRFDDTNPVKEDTEYVDSIIDAVHWLGYSWQNGTGEHLYYASDYFEQLYGFAEVLIQRGAAYIDSQSAEQIAANRGDFTR
PGTPSPFRDRSVEENLALFRDMRAGKYQDGQHVLRARIDMAAPNIVMRDPVLYRIRHAHHHRTGDAWCIYPMYDFTHCIS
DALENITHSLCTLEFENNRPLYDWVLDHLRDAGALPAPLPHQYEFARLHLTYAITSKRKLLQLVNEKRVDGWDDPRMPTL
VGIRRRGYTPESIQLFCERVGVSKADSWIDMSILEAAVRDDLDARAPRSVAVLDPVKLILDNVPADFNEPCSAPVHPKQP
ELGRREFPLTRELWIEREDFTETPPKGYFRLFPGNKVRLRYGYVIECTGCDKDADGNITAVHANIIPDTKSGTPGADSVK
VKGNIHWVSAAHALEAEVRLYDRLFTDPQPDSGDKNFLDALNPDAKRVVTAYLEPTLATAKPEDRFQFERHGYFVADRID
SQPGKPVFNRVVGLKDSWGK

Sequences:

>Translated_580_residues
MSQDNATGAAAASTSNFLRQIIDTDLEQGTYAGRQDTAGHALPPIITRFPPEPNGYLHIGHAKSIWVNFGLAKEYGGRCH
LRFDDTNPVKEDTEYVDSIIDAVHWLGYSWQNGTGEHLYYASDYFEQLYGFAEVLIQRGAAYIDSQSAEQIAANRGDFTR
PGTPSPFRDRSVEENLALFRDMRAGKYQDGQHVLRARIDMAAPNIVMRDPVLYRIRHAHHHRTGDAWCIYPMYDFTHCIS
DALENITHSLCTLEFENNRPLYDWVLDHLRDAGALPAPLPHQYEFARLHLTYAITSKRKLLQLVNEKRVDGWDDPRMPTL
VGIRRRGYTPESIQLFCERVGVSKADSWIDMSILEAAVRDDLDARAPRSVAVLDPVKLILDNVPADFNEPCSAPVHPKQP
ELGRREFPLTRELWIEREDFTETPPKGYFRLFPGNKVRLRYGYVIECTGCDKDADGNITAVHANIIPDTKSGTPGADSVK
VKGNIHWVSAAHALEAEVRLYDRLFTDPQPDSGDKNFLDALNPDAKRVVTAYLEPTLATAKPEDRFQFERHGYFVADRID
SQPGKPVFNRVVGLKDSWGK
>Mature_579_residues
SQDNATGAAAASTSNFLRQIIDTDLEQGTYAGRQDTAGHALPPIITRFPPEPNGYLHIGHAKSIWVNFGLAKEYGGRCHL
RFDDTNPVKEDTEYVDSIIDAVHWLGYSWQNGTGEHLYYASDYFEQLYGFAEVLIQRGAAYIDSQSAEQIAANRGDFTRP
GTPSPFRDRSVEENLALFRDMRAGKYQDGQHVLRARIDMAAPNIVMRDPVLYRIRHAHHHRTGDAWCIYPMYDFTHCISD
ALENITHSLCTLEFENNRPLYDWVLDHLRDAGALPAPLPHQYEFARLHLTYAITSKRKLLQLVNEKRVDGWDDPRMPTLV
GIRRRGYTPESIQLFCERVGVSKADSWIDMSILEAAVRDDLDARAPRSVAVLDPVKLILDNVPADFNEPCSAPVHPKQPE
LGRREFPLTRELWIEREDFTETPPKGYFRLFPGNKVRLRYGYVIECTGCDKDADGNITAVHANIIPDTKSGTPGADSVKV
KGNIHWVSAAHALEAEVRLYDRLFTDPQPDSGDKNFLDALNPDAKRVVTAYLEPTLATAKPEDRFQFERHGYFVADRIDS
QPGKPVFNRVVGLKDSWGK

Specific function: Unknown

COG id: COG0008

COG function: function code J; Glutamyl- and glutaminyl-tRNA synthetases

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family

Homologues:

Organism=Homo sapiens, GI4826960, Length=539, Percent_Identity=46.1966604823748, Blast_Score=434, Evalue=1e-121,
Organism=Homo sapiens, GI62241042, Length=532, Percent_Identity=34.3984962406015, Blast_Score=275, Evalue=8e-74,
Organism=Escherichia coli, GI1786895, Length=571, Percent_Identity=56.3922942206655, Blast_Score=648, Evalue=0.0,
Organism=Escherichia coli, GI1788743, Length=317, Percent_Identity=24.6056782334385, Blast_Score=79, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17543332, Length=541, Percent_Identity=42.8835489833641, Blast_Score=417, Evalue=1e-117,
Organism=Caenorhabditis elegans, GI17511007, Length=517, Percent_Identity=30.5609284332689, Blast_Score=226, Evalue=2e-59,
Organism=Saccharomyces cerevisiae, GI6324742, Length=574, Percent_Identity=41.6376306620209, Blast_Score=412, Evalue=1e-116,
Organism=Saccharomyces cerevisiae, GI6321192, Length=528, Percent_Identity=35.4166666666667, Blast_Score=290, Evalue=3e-79,
Organism=Drosophila melanogaster, GI17864488, Length=539, Percent_Identity=42.4860853432282, Blast_Score=416, Evalue=1e-116,
Organism=Drosophila melanogaster, GI24649466, Length=525, Percent_Identity=32.1904761904762, Blast_Score=252, Evalue=4e-67,

Paralogues:

None

Copy number: 520 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 1200 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): SYQ_RALSO (Q8Y199)

Other databases:

- EMBL:   AL646052
- RefSeq:   NP_518912.1
- ProteinModelPortal:   Q8Y199
- SMR:   Q8Y199
- GeneID:   1219599
- GenomeReviews:   AL646052_GR
- KEGG:   rso:RSc0791
- NMPDR:   fig|267608.1.peg.791
- HOGENOM:   HBG334108
- OMA:   RMPTIAG
- ProtClustDB:   PRK05347
- BioCyc:   RSOL267608:RSC0791-MONOMER
- BRENDA:   6.1.1.18
- GO:   GO:0005737
- HAMAP:   MF_00126
- InterPro:   IPR001412
- InterPro:   IPR004514
- InterPro:   IPR022861
- InterPro:   IPR000924
- InterPro:   IPR020061
- InterPro:   IPR020058
- InterPro:   IPR020059
- InterPro:   IPR020056
- InterPro:   IPR011035
- InterPro:   IPR014729
- Gene3D:   G3DSA:1.10.1160.10
- Gene3D:   G3DSA:2.40.240.10
- Gene3D:   G3DSA:3.40.50.620
- PANTHER:   PTHR10119:SF3
- PANTHER:   PTHR10119
- PRINTS:   PR00987
- TIGRFAMs:   TIGR00440

Pfam domain/function: PF00749 tRNA-synt_1c; PF03950 tRNA-synt_1c_C; SSF50715 Ribosomal_L25rel

EC number: =6.1.1.18

Molecular weight: Translated: 65607; Mature: 65476

Theoretical pI: Translated: 6.15; Mature: 6.15

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: BINDING 297-297

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQDNATGAAAASTSNFLRQIIDTDLEQGTYAGRQDTAGHALPPIITRFPPEPNGYLHIG
CCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHCCCCCCCCEEEEC
HAKSIWVNFGLAKEYGGRCHLRFDDTNPVKEDTEYVDSIIDAVHWLGYSWQNGTGEHLYY
CCCEEEEEECCHHHCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEE
ASDYFEQLYGFAEVLIQRGAAYIDSQSAEQIAANRGDFTRPGTPSPFRDRSVEENLALFR
HHHHHHHHHHHHHHHHHCCCHHHCCCCHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHH
DMRAGKYQDGQHVLRARIDMAAPNIVMRDPVLYRIRHAHHHRTGDAWCIYPMYDFTHCIS
HHHCCCCCCHHHHHHHHHHHCCCCEEECCCHHHHHHHHHCCCCCCEEEEEEHHHHHHHHH
DALENITHSLCTLEFENNRPLYDWVLDHLRDAGALPAPLPHQYEFARLHLTYAITSKRKL
HHHHHHHHHHEEEEECCCCCHHHHHHHHHHHCCCCCCCCCCCCEEEEEEEEEEEHHHHHH
LQLVNEKRVDGWDDPRMPTLVGIRRRGYTPESIQLFCERVGVSKADSWIDMSILEAAVRD
HHHHHHCCCCCCCCCCCCHHHHHHHCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHC
DLDARAPRSVAVLDPVKLILDNVPADFNEPCSAPVHPKQPELGRREFPLTRELWIEREDF
CCCCCCCCCEEEHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHEECCCC
TETPPKGYFRLFPGNKVRLRYGYVIECTGCDKDADGNITAVHANIIPDTKSGTPGADSVK
CCCCCCCEEEECCCCEEEEEEEEEEEEECCCCCCCCCEEEEEEEECCCCCCCCCCCCCEE
VKGNIHWVSAAHALEAEVRLYDRLFTDPQPDSGDKNFLDALNPDAKRVVTAYLEPTLATA
EECCEEEEEHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHCCCCHHHHHHHHHCCHHCCC
KPEDRFQFERHGYFVADRIDSQPGKPVFNRVVGLKDSWGK
CCHHHHHHHHCCEEEEECCCCCCCCHHHHHHHCCCCCCCC
>Mature Secondary Structure 
SQDNATGAAAASTSNFLRQIIDTDLEQGTYAGRQDTAGHALPPIITRFPPEPNGYLHIG
CCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHCCCCCCCCEEEEC
HAKSIWVNFGLAKEYGGRCHLRFDDTNPVKEDTEYVDSIIDAVHWLGYSWQNGTGEHLYY
CCCEEEEEECCHHHCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEE
ASDYFEQLYGFAEVLIQRGAAYIDSQSAEQIAANRGDFTRPGTPSPFRDRSVEENLALFR
HHHHHHHHHHHHHHHHHCCCHHHCCCCHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHH
DMRAGKYQDGQHVLRARIDMAAPNIVMRDPVLYRIRHAHHHRTGDAWCIYPMYDFTHCIS
HHHCCCCCCHHHHHHHHHHHCCCCEEECCCHHHHHHHHHCCCCCCEEEEEEHHHHHHHHH
DALENITHSLCTLEFENNRPLYDWVLDHLRDAGALPAPLPHQYEFARLHLTYAITSKRKL
HHHHHHHHHHEEEEECCCCCHHHHHHHHHHHCCCCCCCCCCCCEEEEEEEEEEEHHHHHH
LQLVNEKRVDGWDDPRMPTLVGIRRRGYTPESIQLFCERVGVSKADSWIDMSILEAAVRD
HHHHHHCCCCCCCCCCCCHHHHHHHCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHC
DLDARAPRSVAVLDPVKLILDNVPADFNEPCSAPVHPKQPELGRREFPLTRELWIEREDF
CCCCCCCCCEEEHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHEECCCC
TETPPKGYFRLFPGNKVRLRYGYVIECTGCDKDADGNITAVHANIIPDTKSGTPGADSVK
CCCCCCCEEEECCCCEEEEEEEEEEEEECCCCCCCCCEEEEEEEECCCCCCCCCCCCCEE
VKGNIHWVSAAHALEAEVRLYDRLFTDPQPDSGDKNFLDALNPDAKRVVTAYLEPTLATA
EECCEEEEEHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHCCCCHHHHHHHHHCCHHCCC
KPEDRFQFERHGYFVADRIDSQPGKPVFNRVVGLKDSWGK
CCHHHHHHHHCCEEEEECCCCCCCCHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11823852