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The map label for this gene is namA [H]

Identifier: 17545421

GI number: 17545421

Start: 749280

End: 750392

Strand: Direct

Name: namA [H]

Synonym: RSc0702

Alternate gene names: 17545421

Gene position: 749280-750392 (Clockwise)

Preceding gene: 17545420

Following gene: 17545428

Centisome position: 20.16

GC content: 71.88

Gene sequence:

>1113_bases
ATGAGCGCGCTCTTCCAGCCTTTTTCCCTGCGCGGGCTTCGGCTCGACAACCGCATCGTCATTTCGCCGATGTGCCAGTA
CTCGGCCGACCAGGGCCAGGCCACGGCATGGCACCAGACGCATCTGGGCGCGCTGTCGCTGTCGGGGGCGGCGCTGCTGA
TGATCGAGGCGACGGCCGTGTCGCCGGAGGGGCGCATCACGCCCGGCTGTCTCGGGTTGTGGGACGACGCCACCGAAGCG
GCGCTGGCCGGGGCGCTGGCCGCCATCCGCCCGCATGCGCAGACACCGATCGGCATCCAGATCGCGCACGCGGGGCGCAA
GGCGTCGAGCGCGCGGCCGTGGGAGGGTGGGGCACTGCTGCCGCCGGAGTCGGGCGGCTGGGAGACCATCGGCCCTTCCG
CGTTGCCGCAGCGCCCGGAGGAGCGGCCGCCGCGCACCATGACCGAGGCTGATCTCGCGCGCGTGCGCGAGGCCTTCGCC
GCCACCGCGCGGCGGGCCGTCGGCCTGGGGCTGGCCGCGATCGAACTGCACGCCGCGCACGGCTATCTGCTGCATGAATT
CCTGTCGCCCCTGGCCAACCAGCGCACCGACGCCTACGGCGGCTCGCGCGAGAACCGCATGCGCTATCCGCTGGAAGTGT
TCGAGGCGGTGCGCGCGGCGGTGCCGGATGACATTCCGGTCGGCGTGCGCGTGTCGTGCACCGACTGGGTCGAGGGCGGC
TGGACGCTGGCGGATTCCGTCGCCTTCGCGCAGGCGCTGCGCGCGCGTGGCTGCGATTGGGTGGATGCGTCGTCGGGCGG
TGTGTCGCCGCTGCAGCAGATTCCGCTGTCCAGCGGGTACCAGGTGCCGTTTGCCGACACCATCCGGCACCAGGCCGGCA
TTCCCACGATCGCGGTCGGGCTGATCAACGAGCCGCACGAGGCCGAGGCCATCCTTGCCGAAGGTCGCGCCGACCTCGTG
GCGATGGGCCGCGCCTTCCTCTACAACCCGCACTGGGCCTGGACGGCCGCAGCCGACCTGGGTGCGACGATCAAGGCGCC
GCCGCAGTACTGGCGCGCGTTTCCGCGCCACGCCAAGAACCTGTTCGGCGAGACGCATTTCGGCGCCCGATAA

Upstream 100 bases:

>100_bases
CCCACCGGGCGCGGGCGTTCTCGCGCCGTCTGCACGATCGGGCGGATTCGGCCACACTGGCGTTCCCGTTCGCCAGCGAC
CGCCAGCCGGTCCCCCGATC

Downstream 100 bases:

>100_bases
GGCGGGGCCGTCGGGTCAGGCGGCGCGCTTGCGGAACACCACGTCCCACACGCCGTGGCCCAGGCGCAGGCCGCGCTTCT
CGAACTTGGTGACGGGGCGG

Product: NADH-dependent flavin oxidoreductase

Products: NA

Alternate protein names: Xenobiotic reductase [H]

Number of amino acids: Translated: 370; Mature: 369

Protein sequence:

>370_residues
MSALFQPFSLRGLRLDNRIVISPMCQYSADQGQATAWHQTHLGALSLSGAALLMIEATAVSPEGRITPGCLGLWDDATEA
ALAGALAAIRPHAQTPIGIQIAHAGRKASSARPWEGGALLPPESGGWETIGPSALPQRPEERPPRTMTEADLARVREAFA
ATARRAVGLGLAAIELHAAHGYLLHEFLSPLANQRTDAYGGSRENRMRYPLEVFEAVRAAVPDDIPVGVRVSCTDWVEGG
WTLADSVAFAQALRARGCDWVDASSGGVSPLQQIPLSSGYQVPFADTIRHQAGIPTIAVGLINEPHEAEAILAEGRADLV
AMGRAFLYNPHWAWTAAADLGATIKAPPQYWRAFPRHAKNLFGETHFGAR

Sequences:

>Translated_370_residues
MSALFQPFSLRGLRLDNRIVISPMCQYSADQGQATAWHQTHLGALSLSGAALLMIEATAVSPEGRITPGCLGLWDDATEA
ALAGALAAIRPHAQTPIGIQIAHAGRKASSARPWEGGALLPPESGGWETIGPSALPQRPEERPPRTMTEADLARVREAFA
ATARRAVGLGLAAIELHAAHGYLLHEFLSPLANQRTDAYGGSRENRMRYPLEVFEAVRAAVPDDIPVGVRVSCTDWVEGG
WTLADSVAFAQALRARGCDWVDASSGGVSPLQQIPLSSGYQVPFADTIRHQAGIPTIAVGLINEPHEAEAILAEGRADLV
AMGRAFLYNPHWAWTAAADLGATIKAPPQYWRAFPRHAKNLFGETHFGAR
>Mature_369_residues
SALFQPFSLRGLRLDNRIVISPMCQYSADQGQATAWHQTHLGALSLSGAALLMIEATAVSPEGRITPGCLGLWDDATEAA
LAGALAAIRPHAQTPIGIQIAHAGRKASSARPWEGGALLPPESGGWETIGPSALPQRPEERPPRTMTEADLARVREAFAA
TARRAVGLGLAAIELHAAHGYLLHEFLSPLANQRTDAYGGSRENRMRYPLEVFEAVRAAVPDDIPVGVRVSCTDWVEGGW
TLADSVAFAQALRARGCDWVDASSGGVSPLQQIPLSSGYQVPFADTIRHQAGIPTIAVGLINEPHEAEAILAEGRADLVA
MGRAFLYNPHWAWTAAADLGATIKAPPQYWRAFPRHAKNLFGETHFGAR

Specific function: Catalyzes the reduction of the double bond of an array of alpha, beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes [H]

COG id: COG1902

COG function: function code C; NADH:flavin oxidoreductases, Old Yellow Enzyme family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NADH:flavin oxidoreductase/NADH oxidase family. NamA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789463, Length=336, Percent_Identity=29.4642857142857, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI1787939, Length=356, Percent_Identity=28.6516853932584, Blast_Score=96, Evalue=4e-21,
Organism=Caenorhabditis elegans, GI17564188, Length=202, Percent_Identity=31.1881188118812, Blast_Score=105, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI72001454, Length=203, Percent_Identity=32.512315270936, Blast_Score=103, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI17559802, Length=178, Percent_Identity=32.0224719101124, Blast_Score=102, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI17559804, Length=179, Percent_Identity=32.4022346368715, Blast_Score=100, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17540738, Length=200, Percent_Identity=29, Blast_Score=97, Evalue=9e-21,
Organism=Caenorhabditis elegans, GI17565138, Length=143, Percent_Identity=35.6643356643357, Blast_Score=93, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17566914, Length=290, Percent_Identity=24.4827586206897, Blast_Score=82, Evalue=5e-16,
Organism=Saccharomyces cerevisiae, GI6325086, Length=236, Percent_Identity=25.4237288135593, Blast_Score=80, Evalue=7e-16,
Organism=Saccharomyces cerevisiae, GI6321973, Length=234, Percent_Identity=25.6410256410256, Blast_Score=79, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR001155 [H]

Pfam domain/function: PF00724 Oxidored_FMN [H]

EC number: =1.6.99.1 [H]

Molecular weight: Translated: 39573; Mature: 39442

Theoretical pI: Translated: 6.65; Mature: 6.65

Prosite motif: PS00659 GLYCOSYL_HYDROL_F5

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSALFQPFSLRGLRLDNRIVISPMCQYSADQGQATAWHQTHLGALSLSGAALLMIEATAV
CCCCCCCCCCCCEEECCEEEECHHHHCCCCCCCCEEEHHHHCCEEECCCEEEEEEEEEEE
SPEGRITPGCLGLWDDATEAALAGALAAIRPHAQTPIGIQIAHAGRKASSARPWEGGALL
CCCCCCCCCEEECCCCHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCCCCCCCCCCEEC
PPESGGWETIGPSALPQRPEERPPRTMTEADLARVREAFAATARRAVGLGLAAIELHAAH
CCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCEEEEEEEHHH
GYLLHEFLSPLANQRTDAYGGSRENRMRYPLEVFEAVRAAVPDDIPVGVRVSCTDWVEGG
HHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCEEEEEHHHCCCC
WTLADSVAFAQALRARGCDWVDASSGGVSPLQQIPLSSGYQVPFADTIRHQAGIPTIAVG
CCHHHHHHHHHHHHHCCCCEEECCCCCCCHHHHCCCCCCCCCCHHHHHHHHCCCCEEEEE
LINEPHEAEAILAEGRADLVAMGRAFLYNPHWAWTAAADLGATIKAPPQYWRAFPRHAKN
CCCCCHHHHHHHHCCCHHHHHHCHHHEECCCCCEEEHHHCCCCCCCCHHHHHHHHHHHHH
LFGETHFGAR
HCCCCCCCCC
>Mature Secondary Structure 
SALFQPFSLRGLRLDNRIVISPMCQYSADQGQATAWHQTHLGALSLSGAALLMIEATAV
CCCCCCCCCCCEEECCEEEECHHHHCCCCCCCCEEEHHHHCCEEECCCEEEEEEEEEEE
SPEGRITPGCLGLWDDATEAALAGALAAIRPHAQTPIGIQIAHAGRKASSARPWEGGALL
CCCCCCCCCEEECCCCHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCCCCCCCCCCEEC
PPESGGWETIGPSALPQRPEERPPRTMTEADLARVREAFAATARRAVGLGLAAIELHAAH
CCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCEEEEEEEHHH
GYLLHEFLSPLANQRTDAYGGSRENRMRYPLEVFEAVRAAVPDDIPVGVRVSCTDWVEGG
HHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCEEEEEHHHCCCC
WTLADSVAFAQALRARGCDWVDASSGGVSPLQQIPLSSGYQVPFADTIRHQAGIPTIAVG
CCHHHHHHHHHHHHHCCCCEEECCCCCCCHHHHCCCCCCCCCCHHHHHHHHCCCCEEEEE
LINEPHEAEAILAEGRADLVAMGRAFLYNPHWAWTAAADLGATIKAPPQYWRAFPRHAKN
CCCCCHHHHHHHHCCCHHHHHHCHHHEECCCCCEEEHHHCCCCCCCCHHHHHHHHHHHHH
LFGETHFGAR
HCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA