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The map label for this gene is apbE [H]

Identifier: 17545330

GI number: 17545330

Start: 658277

End: 659173

Strand: Direct

Name: apbE [H]

Synonym: RSc0611

Alternate gene names: 17545330

Gene position: 658277-659173 (Clockwise)

Preceding gene: 17545329

Following gene: 17545331

Centisome position: 17.71

GC content: 73.02

Gene sequence:

>897_bases
ATGCCGTCGCCCTCAAGTAAGCTGCGCCGCGCCCGGCCGCTGCTCGGGACCCTGGTCGACATCACGGTCAGGGGCCCGGA
CGCGACCTTGCAGGCCGCGCTCGACGCGGCGTTCGCGGCCGTCGAGCGCGTGCAGCGCCTGATGAGCTTTCACGCGGAAG
ACAGCGATGTCTCCCGCATCAACGCCGCCGAGGCGGGCAGCGCGGTCTGCGTCGATGCGCAGACGTACTGCGTGCTGGAG
CGCGCTGTGGCGCTGGGCGAGCTGTCCGACGGCGTGTTCGACATCGCCACGGCGGGCGTGCTGGTGGAGCAGGGCTTTCT
GCCGCGGCACGCCGGCGCGCAGCCTCCCGCTCCGGGGGCGACCTTCCGGGATCTCATCTTGCAGGCGGACCACCGGGTGC
AATGGCGCCGCAAGGGCTGGATCGACCTGGGCGGCATCGCCAAGGGGTACGCCGTCGATTGCGCGATCGCGGCGCTGCGG
GCCCATCGCGTGGACAGCGGCATCGTCAATGCCGGCGGCGACCTGCGCTGCTTCGGCCGGGCGGAACCGATCCATGTGCG
CCGGCCGGATGCGCCGGCCACGCTGGTGCCGCTGGGGTGGCTGCACGATCTGGCCATTGCGACCTCCGGCGGCTATTTCG
CCGGCATCGAGCGCGACGGCCGGCAGATCGATCCGCTGGTCGACCCCGGCCGGCGGGCCTGCGCCGTCTGGGAGGACAGC
ATCAGCGTGGTGGCCGCCGACTGCATGACGGCGGATGCGCTGACCAAGGTGGTGCGCCTCGCGCGTCAGCGCGCGCCCGA
GATCCTCGATCGCTGCCACGCGCAGGCCGTGGTGGTCGGCGCGCAGGCCATCGGCATGTGCGGCGCGCCGCTGCTGCGCA
GGGCCGACGCGCCATGA

Upstream 100 bases:

>100_bases
GCAGATCCGCTGCGCCTGAACGAAGACATCCGCAACATCAGCGGCGCGACGCTGTCGTCGAGGCATATCACCGATGGCGT
GAAGCGGGTGCTGGCCACCT

Downstream 100 bases:

>100_bases
GTTCGCCTCCCGTACCCGTGTTGCGGCTGCCGGTGCGGCTCAGCCAGCGGCACAAGCGCTGGCTGTATGCGACCGGCGCC
GTACTGTGCTGCTCGGGCCT

Product: thiamine biosynthesis lipoprotein apbE precursor transmembrane

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 298; Mature: 297

Protein sequence:

>298_residues
MPSPSSKLRRARPLLGTLVDITVRGPDATLQAALDAAFAAVERVQRLMSFHAEDSDVSRINAAEAGSAVCVDAQTYCVLE
RAVALGELSDGVFDIATAGVLVEQGFLPRHAGAQPPAPGATFRDLILQADHRVQWRRKGWIDLGGIAKGYAVDCAIAALR
AHRVDSGIVNAGGDLRCFGRAEPIHVRRPDAPATLVPLGWLHDLAIATSGGYFAGIERDGRQIDPLVDPGRRACAVWEDS
ISVVAADCMTADALTKVVRLARQRAPEILDRCHAQAVVVGAQAIGMCGAPLLRRADAP

Sequences:

>Translated_298_residues
MPSPSSKLRRARPLLGTLVDITVRGPDATLQAALDAAFAAVERVQRLMSFHAEDSDVSRINAAEAGSAVCVDAQTYCVLE
RAVALGELSDGVFDIATAGVLVEQGFLPRHAGAQPPAPGATFRDLILQADHRVQWRRKGWIDLGGIAKGYAVDCAIAALR
AHRVDSGIVNAGGDLRCFGRAEPIHVRRPDAPATLVPLGWLHDLAIATSGGYFAGIERDGRQIDPLVDPGRRACAVWEDS
ISVVAADCMTADALTKVVRLARQRAPEILDRCHAQAVVVGAQAIGMCGAPLLRRADAP
>Mature_297_residues
PSPSSKLRRARPLLGTLVDITVRGPDATLQAALDAAFAAVERVQRLMSFHAEDSDVSRINAAEAGSAVCVDAQTYCVLER
AVALGELSDGVFDIATAGVLVEQGFLPRHAGAQPPAPGATFRDLILQADHRVQWRRKGWIDLGGIAKGYAVDCAIAALRA
HRVDSGIVNAGGDLRCFGRAEPIHVRRPDAPATLVPLGWLHDLAIATSGGYFAGIERDGRQIDPLVDPGRRACAVWEDSI
SVVAADCMTADALTKVVRLARQRAPEILDRCHAQAVVVGAQAIGMCGAPLLRRADAP

Specific function: Involved in the conversion of aminoimidazole ribotide (AIR), a purine intermediate, to the 4-amino-5-hydroxymethyl-2- methyl pyrimidine (HMP) moiety of thiamine [H]

COG id: COG1477

COG function: function code H; Membrane-associated lipoprotein involved in thiamine biosynthesis

Gene ontology:

Cell location: Cell membrane; Lipid-anchor (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ApbE family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003374 [H]

Pfam domain/function: PF02424 ApbE [H]

EC number: NA

Molecular weight: Translated: 31570; Mature: 31439

Theoretical pI: Translated: 7.13; Mature: 7.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPSPSSKLRRARPLLGTLVDITVRGPDATLQAALDAAFAAVERVQRLMSFHAEDSDVSRI
CCCCHHHHHHHHHHHEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
NAAEAGSAVCVDAQTYCVLERAVALGELSDGVFDIATAGVLVEQGFLPRHAGAQPPAPGA
HHHCCCCEEEECCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
TFRDLILQADHRVQWRRKGWIDLGGIAKGYAVDCAIAALRAHRVDSGIVNAGGDLRCFGR
HHHHHHHHCCCHHHHHHCCCEEECCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCEEEECC
AEPIHVRRPDAPATLVPLGWLHDLAIATSGGYFAGIERDGRQIDPLVDPGRRACAVWEDS
CCCEEEECCCCCCEEEEHHHHHHHHHEECCCEEEEECCCCCEECCCCCCCCCEEEEECCC
ISVVAADCMTADALTKVVRLARQRAPEILDRCHAQAVVVGAQAIGMCGAPLLRRADAP
HHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHEEEHHHHHHHCCCHHHHCCCCC
>Mature Secondary Structure 
PSPSSKLRRARPLLGTLVDITVRGPDATLQAALDAAFAAVERVQRLMSFHAEDSDVSRI
CCCHHHHHHHHHHHEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
NAAEAGSAVCVDAQTYCVLERAVALGELSDGVFDIATAGVLVEQGFLPRHAGAQPPAPGA
HHHCCCCEEEECCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
TFRDLILQADHRVQWRRKGWIDLGGIAKGYAVDCAIAALRAHRVDSGIVNAGGDLRCFGR
HHHHHHHHCCCHHHHHHCCCEEECCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCEEEECC
AEPIHVRRPDAPATLVPLGWLHDLAIATSGGYFAGIERDGRQIDPLVDPGRRACAVWEDS
CCCEEEECCCCCCEEEEHHHHHHHHHEECCCEEEEECCCCCEECCCCCCCCCEEEEECCC
ISVVAADCMTADALTKVVRLARQRAPEILDRCHAQAVVVGAQAIGMCGAPLLRRADAP
HHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHEEEHHHHHHHCCCHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9665876 [H]