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The map label for this gene is corC [H]

Identifier: 17545247

GI number: 17545247

Start: 566799

End: 567695

Strand: Reverse

Name: corC [H]

Synonym: RSc0528

Alternate gene names: 17545247

Gene position: 567695-566799 (Counterclockwise)

Preceding gene: 17545248

Following gene: 17545246

Centisome position: 15.28

GC content: 66.78

Gene sequence:

>897_bases
ATGAATGATCCGTATCCCAGTCCGAAGCCAGCCGACAAACCCCGCTCGCTGCTGGAACGCCTGACCGATCTCATCTCGCC
CGAGCCCGAGTCGCGGGCCGAGCTGCTGGAAATCCTCCAAGACGCGCACGCGCGCAACCTGATCGATGCCGACTCCCTGT
CGATGATCGAAGGGGTCTTCCAGGTCTCCGACCTGTGCGCGCGCGACATCATGATCCCCCGCGCGCAGATGGACGCGATC
AACATCGCCGACGCGCCCGCCGAATTCATCCCCTTCGTCCAGCAGGCCGCGCATTCGCGCTTCCCCGTCTACGAGGGCAG
CCGCGACAACATCATCGGCATCCTGCTGGCCAAGGACCTGCTGCGCTACTACACGGACGAAGGCTTCGACGTGCGCGACA
TGCTGCGCCCGGCCGTGTTCATTCCCGAATCCAAGCGGCTGAACGTGCTGCTGCGCGACTTCCGCGTCAACCGCAACCAC
ATCGCCATCGTCGTCGATGAATACGGCGGCGTGGCCGGCCTGATCACCATCGAAGACGTGCTGGAGCAGATCGTCGGCGA
CATCGAGGACGAATACGATTTCGACCAGGAGGAAGACAACATCCTCCCCACCGCCGACGGCCACATGCGCGTGCGCGGGC
TGACCGAGATCAGCCAGTTCAACGAAGCCTTCGGCACGCACTTCTCCGACGAGGACGTCGACACCGTCGGCGGCCTGCTC
GCCAACCACCTGGGCCGCGTGCCGCACCGGGGCGAGAAGATCGTGCTGGGCACGCTGCAGTTCGACGTGCTGCGCGCCGA
TGCGCGCCAGGTGCAGGTGCTGCTGGTGCGCCACCTCGCCGCACCCGCGCCGGGCGCCGCCGCCCCGGCCGACCCGTCCC
GCTCCAACCCCGCCTGA

Upstream 100 bases:

>100_bases
GGAGCAACCGCCCGCGCCGCCGCACGGCGCCGGGCCGTCATCGGGAGGGCCTGCCTTTTGGTGTATGCTGGGCTGATGTG
TAACAACGCGCCTTCGCGCC

Downstream 100 bases:

>100_bases
TCGCCTGAGTTCGTTTTCCGTGCGCGCTTTGTTCTCCTCTCCTGCCGCCGACACCGCTGGCCAGCAGGAAGCCCTGGCCG
TGCCGCTTGCCCGGCTGCGC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 298; Mature: 298

Protein sequence:

>298_residues
MNDPYPSPKPADKPRSLLERLTDLISPEPESRAELLEILQDAHARNLIDADSLSMIEGVFQVSDLCARDIMIPRAQMDAI
NIADAPAEFIPFVQQAAHSRFPVYEGSRDNIIGILLAKDLLRYYTDEGFDVRDMLRPAVFIPESKRLNVLLRDFRVNRNH
IAIVVDEYGGVAGLITIEDVLEQIVGDIEDEYDFDQEEDNILPTADGHMRVRGLTEISQFNEAFGTHFSDEDVDTVGGLL
ANHLGRVPHRGEKIVLGTLQFDVLRADARQVQVLLVRHLAAPAPGAAAPADPSRSNPA

Sequences:

>Translated_298_residues
MNDPYPSPKPADKPRSLLERLTDLISPEPESRAELLEILQDAHARNLIDADSLSMIEGVFQVSDLCARDIMIPRAQMDAI
NIADAPAEFIPFVQQAAHSRFPVYEGSRDNIIGILLAKDLLRYYTDEGFDVRDMLRPAVFIPESKRLNVLLRDFRVNRNH
IAIVVDEYGGVAGLITIEDVLEQIVGDIEDEYDFDQEEDNILPTADGHMRVRGLTEISQFNEAFGTHFSDEDVDTVGGLL
ANHLGRVPHRGEKIVLGTLQFDVLRADARQVQVLLVRHLAAPAPGAAAPADPSRSNPA
>Mature_298_residues
MNDPYPSPKPADKPRSLLERLTDLISPEPESRAELLEILQDAHARNLIDADSLSMIEGVFQVSDLCARDIMIPRAQMDAI
NIADAPAEFIPFVQQAAHSRFPVYEGSRDNIIGILLAKDLLRYYTDEGFDVRDMLRPAVFIPESKRLNVLLRDFRVNRNH
IAIVVDEYGGVAGLITIEDVLEQIVGDIEDEYDFDQEEDNILPTADGHMRVRGLTEISQFNEAFGTHFSDEDVDTVGGLL
ANHLGRVPHRGEKIVLGTLQFDVLRADARQVQVLLVRHLAAPAPGAAAPADPSRSNPA

Specific function: Plays a role in the transport of magnesium and cobalt ions [H]

COG id: COG4535

COG function: function code P; Putative Mg2+ and Co2+ transporter CorC

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains [H]

Homologues:

Organism=Homo sapiens, GI310128564, Length=209, Percent_Identity=31.5789473684211, Blast_Score=117, Evalue=2e-26,
Organism=Homo sapiens, GI40068053, Length=179, Percent_Identity=27.9329608938547, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI40068055, Length=179, Percent_Identity=27.9329608938547, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI94681046, Length=178, Percent_Identity=29.2134831460674, Blast_Score=72, Evalue=7e-13,
Organism=Escherichia coli, GI1786879, Length=253, Percent_Identity=47.4308300395257, Blast_Score=209, Evalue=2e-55,
Organism=Escherichia coli, GI145693175, Length=265, Percent_Identity=29.4339622641509, Blast_Score=122, Evalue=3e-29,
Organism=Escherichia coli, GI87082033, Length=243, Percent_Identity=26.7489711934156, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1788119, Length=224, Percent_Identity=33.4821428571429, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1790664, Length=249, Percent_Identity=24.8995983935743, Blast_Score=73, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR000644
- InterPro:   IPR005170 [H]

Pfam domain/function: PF00571 CBS; PF03471 CorC_HlyC [H]

EC number: NA

Molecular weight: Translated: 33064; Mature: 33064

Theoretical pI: Translated: 4.37; Mature: 4.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNDPYPSPKPADKPRSLLERLTDLISPEPESRAELLEILQDAHARNLIDADSLSMIEGVF
CCCCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
QVSDLCARDIMIPRAQMDAINIADAPAEFIPFVQQAAHSRFPVYEGSRDNIIGILLAKDL
HHHHHHHHHHCCCCHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCEEHHHHHHHH
LRYYTDEGFDVRDMLRPAVFIPESKRLNVLLRDFRVNRNHIAIVVDEYGGVAGLITIEDV
HHHHCCCCCCHHHHHCCCEECCCCCHHHHHHHHHCCCCCEEEEEEECCCCEEEEEEHHHH
LEQIVGDIEDEYDFDQEEDNILPTADGHMRVRGLTEISQFNEAFGTHFSDEDVDTVGGLL
HHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHCCCCCCCHHHHHHHHH
ANHLGRVPHRGEKIVLGTLQFDVLRADARQVQVLLVRHLAAPAPGAAAPADPSRSNPA
HHHHCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MNDPYPSPKPADKPRSLLERLTDLISPEPESRAELLEILQDAHARNLIDADSLSMIEGVF
CCCCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
QVSDLCARDIMIPRAQMDAINIADAPAEFIPFVQQAAHSRFPVYEGSRDNIIGILLAKDL
HHHHHHHHHHCCCCHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCEEHHHHHHHH
LRYYTDEGFDVRDMLRPAVFIPESKRLNVLLRDFRVNRNHIAIVVDEYGGVAGLITIEDV
HHHHCCCCCCHHHHHCCCEECCCCCHHHHHHHHHCCCCCEEEEEEECCCCEEEEEEHHHH
LEQIVGDIEDEYDFDQEEDNILPTADGHMRVRGLTEISQFNEAFGTHFSDEDVDTVGGLL
HHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHCCCCCCCHHHHHHHHH
ANHLGRVPHRGEKIVLGTLQFDVLRADARQVQVLLVRHLAAPAPGAAAPADPSRSNPA
HHHHCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]