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The map label for this gene is tpm [H]

Identifier: 17545181

GI number: 17545181

Start: 493457

End: 494086

Strand: Direct

Name: tpm [H]

Synonym: RSc0462

Alternate gene names: 17545181

Gene position: 493457-494086 (Clockwise)

Preceding gene: 17545180

Following gene: 17545182

Centisome position: 13.28

GC content: 73.33

Gene sequence:

>630_bases
ATGGCCCAACCGCCCGTCTTCACCACCCGCGATGCCGCCGCCCCCGCGTTCTGGGACGAGCGCTTCAGCCGCGACCACAT
GCCTTGGGACGCGCACGGCGTGCCGCCGGCCTTCCGCCAGTTCTGCGAAGCGCAGCCCGCGCCGCTCTCCACGCTGATCC
CCGGCTGCGGCAGCGCCTACGAGGCGGGCTGGCTGGCCGAGCGCGGCTGGCCCGTCGCCGCCATCGACTTCGCGCCGAGT
GCGGTGGCCTCCGCACAGGCCGTGCTGGGGCCGCATGCTGGCGTGGTCGAACTGGCCGATTTTTTCCGGTTCACGCCGCG
CCAGCCGGTGCAATGGATCTACGAGCGCGCCTTCCTGTGCGCGATGCCGCGCCGGCTGTGGGCGGATTACGCCACGCAGG
TCGCGCGGCTGCTGCCGCCCGGCGGGTTGCTGGCCGGGTTCTTCGTGGTGGTCGACGGCCGGGCCGCCGCGCCTAGCGGG
CCGCCGTTCGAGATCACGGCGCAGGAGCAGGAGGCGCTGCTGTCGCCGGCCTTCGAGCGGATTGCCGATGCGCTGGTCCC
CGAGAACGAATCGATACCCGTGTTCGCCGGGCGCGAGCGTTGGCAGGTCTGGCGCCGCCGCGCCGACTGA

Upstream 100 bases:

>100_bases
GCGGCGCTGCTGTTCATCGGCGGCTTTGCGGTCGGCATCATTGCCACGCATGTGCTGGCGTGGCTGGCCCGCCACTGACC
GCCGACCGACTCTGACCCGC

Downstream 100 bases:

>100_bases
CTCCGGCGCCTTTAGCGCCACAGGGGCACGCCCGGGGCAGGGCACGGTGTTGGTGCTGAGCAACATGGCCGATCACCCGG
AAAAAGCCTGCGGACGCCTG

Product: hypothetical protein

Products: NA

Alternate protein names: Thiopurine methyltransferase [H]

Number of amino acids: Translated: 209; Mature: 208

Protein sequence:

>209_residues
MAQPPVFTTRDAAAPAFWDERFSRDHMPWDAHGVPPAFRQFCEAQPAPLSTLIPGCGSAYEAGWLAERGWPVAAIDFAPS
AVASAQAVLGPHAGVVELADFFRFTPRQPVQWIYERAFLCAMPRRLWADYATQVARLLPPGGLLAGFFVVVDGRAAAPSG
PPFEITAQEQEALLSPAFERIADALVPENESIPVFAGRERWQVWRRRAD

Sequences:

>Translated_209_residues
MAQPPVFTTRDAAAPAFWDERFSRDHMPWDAHGVPPAFRQFCEAQPAPLSTLIPGCGSAYEAGWLAERGWPVAAIDFAPS
AVASAQAVLGPHAGVVELADFFRFTPRQPVQWIYERAFLCAMPRRLWADYATQVARLLPPGGLLAGFFVVVDGRAAAPSG
PPFEITAQEQEALLSPAFERIADALVPENESIPVFAGRERWQVWRRRAD
>Mature_208_residues
AQPPVFTTRDAAAPAFWDERFSRDHMPWDAHGVPPAFRQFCEAQPAPLSTLIPGCGSAYEAGWLAERGWPVAAIDFAPSA
VASAQAVLGPHAGVVELADFFRFTPRQPVQWIYERAFLCAMPRRLWADYATQVARLLPPGGLLAGFFVVVDGRAAAPSGP
PFEITAQEQEALLSPAFERIADALVPENESIPVFAGRERWQVWRRRAD

Specific function: Unknown

COG id: COG0500

COG function: function code QR; SAM-dependent methyltransferases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. TPMT family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022474
- InterPro:   IPR008854
- InterPro:   IPR016822 [H]

Pfam domain/function: PF05724 TPMT [H]

EC number: =2.1.1.67 [H]

Molecular weight: Translated: 23014; Mature: 22883

Theoretical pI: Translated: 5.03; Mature: 5.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQPPVFTTRDAAAPAFWDERFSRDHMPWDAHGVPPAFRQFCEAQPAPLSTLIPGCGSAY
CCCCCCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCHHHHHHHCCCCCCHHHHCCCCCCCH
EAGWLAERGWPVAAIDFAPSAVASAQAVLGPHAGVVELADFFRFTPRQPVQWIYERAFLC
HCCCHHCCCCCEEEECCCCHHHHHHHHHHCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHH
AMPRRLWADYATQVARLLPPGGLLAGFFVVVDGRAAAPSGPPFEITAQEQEALLSPAFER
HHHHHHHHHHHHHHHHHCCCCHHHEEEHHEECCCCCCCCCCCEEEECHHHHHHHHHHHHH
IADALVPENESIPVFAGRERWQVWRRRAD
HHHHHCCCCCCCCEEECHHHHHHHHHCCC
>Mature Secondary Structure 
AQPPVFTTRDAAAPAFWDERFSRDHMPWDAHGVPPAFRQFCEAQPAPLSTLIPGCGSAY
CCCCCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCHHHHHHHCCCCCCHHHHCCCCCCCH
EAGWLAERGWPVAAIDFAPSAVASAQAVLGPHAGVVELADFFRFTPRQPVQWIYERAFLC
HCCCHHCCCCCEEEECCCCHHHHHHHHHHCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHH
AMPRRLWADYATQVARLLPPGGLLAGFFVVVDGRAAAPSGPPFEITAQEQEALLSPAFER
HHHHHHHHHHHHHHHHHCCCCHHHEEEHHEECCCCCCCCCCCEEEECHHHHHHHHHHHHH
IADALVPENESIPVFAGRERWQVWRRRAD
HHHHHCCCCCCCCEEECHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA