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The map label for this gene is grxC [H]

Identifier: 17545074

GI number: 17545074

Start: 386644

End: 386901

Strand: Direct

Name: grxC [H]

Synonym: RSc0355

Alternate gene names: 17545074

Gene position: 386644-386901 (Clockwise)

Preceding gene: 17545073

Following gene: 17545075

Centisome position: 10.4

GC content: 65.5

Gene sequence:

>258_bases
ATGGCCCACGTCGTCATGTACAGCACGACCGTCTGCCCCTATTGCGTGGCGGCGGAGAAGCTCCTGAAGCAGCGCGGCGT
CGCGCATATCGAAAAGATCCTGATCGATCGCGAGCCCGGCAGGCGCGAAGAGATGATGACGCGCACCAACCGCCGGACCG
TGCCGCAGATCTACATCGATGACCGCCATATCGGTGGCTTCGACGACCTCTCGGCGCTCGACCGCGAAGGCGGGCTGGAG
CCGCTGCTGGCGGCCTGA

Upstream 100 bases:

>100_bases
GTTGAAGCAGGCCGGTTACAGTGAGGTCTATTCGCTCGAGGGCGGATTGGCCGCCTGGCAGCAGGCCGGCCTGCCGATCG
TCAAATAACGAGGTTTTTCC

Downstream 100 bases:

>100_bases
CGGCCCCCGCGAAAACGCCCGGCTCCGGCCGGGCGTTGTACTTTTAGGCCGGCTCCGATGGCGCCCCGCGTGCCGTCATG
TACCATACGCGTCTTGCGCG

Product: glutaredoxin 3 (GRX3) protein

Products: NA

Alternate protein names: Grx3 [H]

Number of amino acids: Translated: 85; Mature: 84

Protein sequence:

>85_residues
MAHVVMYSTTVCPYCVAAEKLLKQRGVAHIEKILIDREPGRREEMMTRTNRRTVPQIYIDDRHIGGFDDLSALDREGGLE
PLLAA

Sequences:

>Translated_85_residues
MAHVVMYSTTVCPYCVAAEKLLKQRGVAHIEKILIDREPGRREEMMTRTNRRTVPQIYIDDRHIGGFDDLSALDREGGLE
PLLAA
>Mature_84_residues
AHVVMYSTTVCPYCVAAEKLLKQRGVAHIEKILIDREPGRREEMMTRTNRRTVPQIYIDDRHIGGFDDLSALDREGGLEP
LLAA

Specific function: The disulfide bond functions as an electron carrier in the glutathione-dependent synthesis of deoxyribonucleotides by the enzyme ribonucleotide reductase. In addition, it is also involved in reducing some disulfides in a coupled system with glutathione re

COG id: COG0695

COG function: function code O; Glutaredoxin and related proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutaredoxin domain [H]

Homologues:

Organism=Escherichia coli, GI1790039, Length=83, Percent_Identity=53.0120481927711, Blast_Score=92, Evalue=8e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011767
- InterPro:   IPR002109
- InterPro:   IPR014025
- InterPro:   IPR011900
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00462 Glutaredoxin [H]

EC number: NA

Molecular weight: Translated: 9639; Mature: 9508

Theoretical pI: Translated: 6.78; Mature: 6.78

Prosite motif: PS00195 GLUTAREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
7.1 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAHVVMYSTTVCPYCVAAEKLLKQRGVAHIEKILIDREPGRREEMMTRTNRRTVPQIYID
CCEEEEECCCCCHHHHHHHHHHHHCCHHHHHHHHHCCCCCCHHHHHHHCCCCCCCEEEEC
DRHIGGFDDLSALDREGGLEPLLAA
CCCCCCCHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
AHVVMYSTTVCPYCVAAEKLLKQRGVAHIEKILIDREPGRREEMMTRTNRRTVPQIYID
CEEEEECCCCCHHHHHHHHHHHHCCHHHHHHHHHCCCCCCHHHHHHHCCCCCCCEEEEC
DRHIGGFDDLSALDREGGLEPLLAA
CCCCCCCHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]